Patents Assigned to Cytori Therapeutics, Inc.
  • Publication number: 20130108592
    Abstract: Aspects of the present invention relate to the field of medicine, specifically, the effect of adipose tissue and its components on modulating inflammation.
    Type: Application
    Filed: December 19, 2012
    Publication date: May 2, 2013
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventor: CYTORI THERAPEUTICS, INC.
  • Patent number: 8404229
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients, including patients with renal conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic renal benefit.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: March 26, 2013
    Assignee: Cytori Therapeutics, Inc.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Publication number: 20130060338
    Abstract: The present invention relates to a device comprising a cell carrier portion containing regenerative cells, e.g., stem and progenitor cells, and a cell carrier containment portion. The device is useful for the treatment of bone related disorders, including spinal fusion related disorders and long bone or flat bone related defects. The device may be used in conjunction with disclosed automated systems and methods for separating and concentrating regenerative cells.
    Type: Application
    Filed: August 29, 2012
    Publication date: March 7, 2013
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: Marc H. Hedrick, John K. Fraser, Susan Lynn Riley, Joseph W. Tai
  • Patent number: 8337834
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: December 25, 2012
    Assignee: Cytori Therapeutics, Inc.
    Inventors: John K. Fraser, Marc H. Hedrick
  • Publication number: 20120315257
    Abstract: Cells present in adipose tissue are used to treat patients, including patients with PVD and related diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Application
    Filed: August 16, 2012
    Publication date: December 13, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Publication number: 20120308536
    Abstract: Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of cells comprising disaggregated adipose-derived stem cells, mixing the concentrated population of adipose-derived cells comprising disaggregated adipose-derived cells with a portion of unprocessed, intact, non-disaggregated adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.
    Type: Application
    Filed: August 17, 2012
    Publication date: December 6, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: Marc H. Hedrick, John K. Fraser
  • Publication number: 20120308518
    Abstract: Cells present in adipose tissue are used to stroke and stroke related diseases and disorders in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Application
    Filed: August 15, 2012
    Publication date: December 6, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: John K. Fraser, Marc H. Hedrick, Brian M. Strem
  • Publication number: 20120264200
    Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
    Type: Application
    Filed: April 20, 2012
    Publication date: October 18, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Rhonda Elizabeth Schreiber, Isabella Wulur
  • Publication number: 20120259289
    Abstract: Embodiments disclosed herein relate to syringe systems for delivering and removing materials, instrument kits that include the syringe systems provided herein, and methods of using the syringe systems and kits provided herein.
    Type: Application
    Filed: April 18, 2012
    Publication date: October 11, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: Bobby L. Byrnes, Robert K. Shanahan, Douglas Arm, Jonathan Costabile, Jose F. Curiel
  • Publication number: 20120221253
    Abstract: A method and apparatus for billing entities for use of a medical device, which relates to the processing of regenerative cells to facilitate at least one of hard and soft tissue formation, are described. When an operator uses the medical device, a corresponding charge is determined. Billing for usage of the medical device is performed on a periodic or per-use basis. Communication over a network facilitates remote management and servicing of the medical device. Support is provided for automatic ordering of supplies consumed by the medical device.
    Type: Application
    Filed: May 9, 2012
    Publication date: August 30, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: Marc H. Hedrick, Christopher Calhoun
  • Patent number: 8246947
    Abstract: Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of cells comprising disaggregated adipose-derived stem cells, mixing the concentrated population of adipose-derived cells comprising disaggregated adipose-derived cells with a portion of unprocessed, intact, non-disaggregated adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.
    Type: Grant
    Filed: January 26, 2010
    Date of Patent: August 21, 2012
    Assignee: Cytori Therapeutics, Inc.
    Inventors: Marc H. Hedrick, John K. Fraser
  • Publication number: 20120121556
    Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Application
    Filed: January 27, 2012
    Publication date: May 17, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Patent number: 8163276
    Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: April 24, 2012
    Assignee: Cytori Therapeutics, Inc.
    Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Schreiber, Isabella Wulur
  • Publication number: 20120093783
    Abstract: Aspects of the present invention relate to the field of medicine, specifically, the effect of adipose tissue and its components on modulating inflammation.
    Type: Application
    Filed: October 21, 2011
    Publication date: April 19, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: Kai Pinkernell, Zheng Feng
  • Publication number: 20120058093
    Abstract: Cells present in adipose tissue are used to treat patients, including patients with PVD and related diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Patent number: 8119121
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: February 21, 2012
    Assignee: Cytori Therapeutics, Inc.
    Inventors: John K. Fraser, Marc H. Hedrick
  • Patent number: 8105580
    Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: January 31, 2012
    Assignee: Cytori Therapeutics, Inc.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Publication number: 20110294203
    Abstract: A cell cluster from which unwanted components are removed by efficiently washing the cell cluster is collected. Provided is a cell washing method including a centrifuging step (S1) of collecting a cell suspension in a centrifuge container having a washing fluid discharge port opposing a bottom part and centrifugally separating cells at the bottom part by rotating in such a manner that the bottom part faces outward in the radial direction; a supernatant ejecting step (S2) of ejecting a supernatant centrifugally separated in the centrifuging step (S1); and a washing step (S3) of discharging the washing fluid from the discharge port while rotating the centrifuge container while ejecting the supernatant in the supernatant ejecting step (S2).
    Type: Application
    Filed: June 17, 2011
    Publication date: December 1, 2011
    Applicants: CYTORI THERAPEUTICS, INC., OLYMPUS CORPORATION
    Inventors: Hiroki TSUCHIDA, Chisato KARASAWA, Kazuhiro YOSHIDA, Robert K. SHANAHAN, Lucas V. FORNACE
  • Publication number: 20110230328
    Abstract: A cell suspension that contains a cell group from which unwanted components have been removed by efficiently washing the cell group is recovered. A centrifuge container (1) includes a cylindrical container main body (2) that accommodates a cell suspension and is rotated with a bottom portion (2a) being directed radially outward; a supernatant suction tube (4) that has a first opening (4a) at a position in the depth direction of the container main body (2) and that suctions a supernatant obtained by centrifuging the cell suspension, in the radial direction of the container main body (2); and a washing-fluid discharge tube (3) that have a second opening (3a) at a position in the depth direction of the container main body (2) and that discharge a washing fluid in the axial direction toward the bottom portion (2a) of the container main body (2).
    Type: Application
    Filed: March 21, 2011
    Publication date: September 22, 2011
    Applicants: OLYMPUS CORPORATION, CYTORI THERAPEUTICS, INC.
    Inventors: Aki KINOSHITA, Douglas M. ARM, Robert K. SHANAHAN, Lucas V. FORNACE
  • Publication number: 20110158968
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
    Type: Application
    Filed: March 7, 2011
    Publication date: June 30, 2011
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: John K. Fraser, Marc H. Hedrick