Patents Assigned to Cytori Therapeutics, Inc.
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Publication number: 20130108592Abstract: Aspects of the present invention relate to the field of medicine, specifically, the effect of adipose tissue and its components on modulating inflammation.Type: ApplicationFiled: December 19, 2012Publication date: May 2, 2013Applicant: CYTORI THERAPEUTICS, INC.Inventor: CYTORI THERAPEUTICS, INC.
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Patent number: 8404229Abstract: Cells present in processed lipoaspirate tissue are used to treat patients, including patients with renal conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic renal benefit.Type: GrantFiled: July 1, 2004Date of Patent: March 26, 2013Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Publication number: 20130060338Abstract: The present invention relates to a device comprising a cell carrier portion containing regenerative cells, e.g., stem and progenitor cells, and a cell carrier containment portion. The device is useful for the treatment of bone related disorders, including spinal fusion related disorders and long bone or flat bone related defects. The device may be used in conjunction with disclosed automated systems and methods for separating and concentrating regenerative cells.Type: ApplicationFiled: August 29, 2012Publication date: March 7, 2013Applicant: CYTORI THERAPEUTICS, INC.Inventors: Marc H. Hedrick, John K. Fraser, Susan Lynn Riley, Joseph W. Tai
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Patent number: 8337834Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: March 7, 2011Date of Patent: December 25, 2012Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Publication number: 20120315257Abstract: Cells present in adipose tissue are used to treat patients, including patients with PVD and related diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: ApplicationFiled: August 16, 2012Publication date: December 13, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Publication number: 20120308536Abstract: Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of cells comprising disaggregated adipose-derived stem cells, mixing the concentrated population of adipose-derived cells comprising disaggregated adipose-derived cells with a portion of unprocessed, intact, non-disaggregated adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.Type: ApplicationFiled: August 17, 2012Publication date: December 6, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: Marc H. Hedrick, John K. Fraser
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Publication number: 20120308518Abstract: Cells present in adipose tissue are used to stroke and stroke related diseases and disorders in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: ApplicationFiled: August 15, 2012Publication date: December 6, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick, Brian M. Strem
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Publication number: 20120264200Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.Type: ApplicationFiled: April 20, 2012Publication date: October 18, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Rhonda Elizabeth Schreiber, Isabella Wulur
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Publication number: 20120259289Abstract: Embodiments disclosed herein relate to syringe systems for delivering and removing materials, instrument kits that include the syringe systems provided herein, and methods of using the syringe systems and kits provided herein.Type: ApplicationFiled: April 18, 2012Publication date: October 11, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: Bobby L. Byrnes, Robert K. Shanahan, Douglas Arm, Jonathan Costabile, Jose F. Curiel
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Publication number: 20120221253Abstract: A method and apparatus for billing entities for use of a medical device, which relates to the processing of regenerative cells to facilitate at least one of hard and soft tissue formation, are described. When an operator uses the medical device, a corresponding charge is determined. Billing for usage of the medical device is performed on a periodic or per-use basis. Communication over a network facilitates remote management and servicing of the medical device. Support is provided for automatic ordering of supplies consumed by the medical device.Type: ApplicationFiled: May 9, 2012Publication date: August 30, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: Marc H. Hedrick, Christopher Calhoun
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Patent number: 8246947Abstract: Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of cells comprising disaggregated adipose-derived stem cells, mixing the concentrated population of adipose-derived cells comprising disaggregated adipose-derived cells with a portion of unprocessed, intact, non-disaggregated adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.Type: GrantFiled: January 26, 2010Date of Patent: August 21, 2012Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser
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Publication number: 20120121556Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: ApplicationFiled: January 27, 2012Publication date: May 17, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Patent number: 8163276Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.Type: GrantFiled: September 4, 2009Date of Patent: April 24, 2012Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Schreiber, Isabella Wulur
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Publication number: 20120093783Abstract: Aspects of the present invention relate to the field of medicine, specifically, the effect of adipose tissue and its components on modulating inflammation.Type: ApplicationFiled: October 21, 2011Publication date: April 19, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: Kai Pinkernell, Zheng Feng
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Publication number: 20120058093Abstract: Cells present in adipose tissue are used to treat patients, including patients with PVD and related diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: ApplicationFiled: November 14, 2011Publication date: March 8, 2012Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Patent number: 8119121Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: July 7, 2003Date of Patent: February 21, 2012Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Patent number: 8105580Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: GrantFiled: July 1, 2004Date of Patent: January 31, 2012Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Publication number: 20110294203Abstract: A cell cluster from which unwanted components are removed by efficiently washing the cell cluster is collected. Provided is a cell washing method including a centrifuging step (S1) of collecting a cell suspension in a centrifuge container having a washing fluid discharge port opposing a bottom part and centrifugally separating cells at the bottom part by rotating in such a manner that the bottom part faces outward in the radial direction; a supernatant ejecting step (S2) of ejecting a supernatant centrifugally separated in the centrifuging step (S1); and a washing step (S3) of discharging the washing fluid from the discharge port while rotating the centrifuge container while ejecting the supernatant in the supernatant ejecting step (S2).Type: ApplicationFiled: June 17, 2011Publication date: December 1, 2011Applicants: CYTORI THERAPEUTICS, INC., OLYMPUS CORPORATIONInventors: Hiroki TSUCHIDA, Chisato KARASAWA, Kazuhiro YOSHIDA, Robert K. SHANAHAN, Lucas V. FORNACE
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Publication number: 20110230328Abstract: A cell suspension that contains a cell group from which unwanted components have been removed by efficiently washing the cell group is recovered. A centrifuge container (1) includes a cylindrical container main body (2) that accommodates a cell suspension and is rotated with a bottom portion (2a) being directed radially outward; a supernatant suction tube (4) that has a first opening (4a) at a position in the depth direction of the container main body (2) and that suctions a supernatant obtained by centrifuging the cell suspension, in the radial direction of the container main body (2); and a washing-fluid discharge tube (3) that have a second opening (3a) at a position in the depth direction of the container main body (2) and that discharge a washing fluid in the axial direction toward the bottom portion (2a) of the container main body (2).Type: ApplicationFiled: March 21, 2011Publication date: September 22, 2011Applicants: OLYMPUS CORPORATION, CYTORI THERAPEUTICS, INC.Inventors: Aki KINOSHITA, Douglas M. ARM, Robert K. SHANAHAN, Lucas V. FORNACE
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Publication number: 20110158968Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: ApplicationFiled: March 7, 2011Publication date: June 30, 2011Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick