Patents Assigned to D
  • Device for heating a system for distributing windscreen-washer liquid of a motor vehicle, hydraulic coupling including such a device and associated assembly method
    Patent number: 10988117
    Abstract: A heating device for a system for distributing windshield washer fluid of a motor vehicle. The heating device may include a sleeve comprising two flow channels for distributing the windshield washer fluid, the two flow channels being parallel to one another. The heating device may include at least two heating conductors embedded in a mass of the sleeve. The heating device may include a current regulator controlling the current flowing in the heating conductors as a function of a temperature of said heating conductors.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: April 27, 2021
    Assignee: Valeo Systèmes d'Essuyage
    Inventors: Geoffrey Bayard, Nadia Berthon
  • Systems and methods for fabrication of superconducting integrated circuits
    Patent number: 10991755
    Abstract: Various techniques and apparatus permit fabrication of superconductive circuits and structures, for instance Josephson junctions, which may, for example be useful in quantum computers. For instance, a low magnetic flux noise trilayer structure may be fabricated having a dielectric structure or layer interposed between two elements or layers capable of superconducting. A superconducting via may directly overlie a Josephson junction. A structure, for instance a Josephson junction, may be carried on a planarized dielectric layer. A fin may be employed to remove heat from the structure. A via capable of superconducting may have a width that is less than about 1 micrometer. The structure may be coupled to a resistor, for example by vias and/or a strap connector.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: April 27, 2021
    Assignee: D-WAVE SYSTEMS INC.
    Inventors: Eric Ladizinsky, Geordie Rose, Jeremy P. Hilton, Eugene Dantsker, Byong Hyop Oh
  • Fiber optic shelving system
    Patent number: 10989856
    Abstract: A fiber optic shelving system includes a shelf including a plurality of holes, a plurality of fiber optic filaments, each of the plurality of fiber optic filaments having a first end and a second end, and the first end being coupled to one of the plurality of holes, a first camera configured to capture an image of the terminal surfaces of the plurality of fiber optic filaments, and a second camera configured to capture an image of a side of one or more products on the shelf. The fiber optic shelving system identifies, among the plurality of holes, a set of holes that are blocked from light based on the captured image of terminal surfaces of the second ends of the plurality of fiber optic filaments, and determines a number of products on the shelf based on the identified set of holes blocked from light and the captured image of the side of one or more products on the shelf.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: April 27, 2021
    Assignee: SUNRISE R&D HOLDINGS, LLC
    Inventors: John Christopher Goss, Gregory Daniel Noble, Kevin Michael Roa, Douglas Steven Meiser
  • Cosmetic agent formed by galactomannans obtained from and cross-linked sulphated galactans obtained from
    Patent number: 10987297
    Abstract: A cosmetic or dermocosmetic agent consisting of galactomannans with molecular masses in a range from 1 to 150 kDa obtained from Caesalpinia spinose and cross-linked sulfated galactans with molar masses in a range from 1 to 150 kDa obtained from Kappaphycus alvarezii. Non-therapeutic cosmetic methods in which the agent is applied on the skin in order to tens the skin and/or to form a film on the skin.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: April 27, 2021
    Assignee: SOCIETE INDUSTRIELLE LIMOUSINE D'APPLICATION BIOLOGIQUE
    Inventor: Jean Paufique
  • Hybrid type rotorcraft having a horizontal stabilizer and two fins arranged on the horizontal stabilizer
    Patent number: 10988235
    Abstract: A hybrid type rotorcraft having a main rotor, at least two propulsion elements each mounted on respective half-wings arranged symmetrically on either side of an anteroposterior midplane XOZ, a horizontal stabilizer arranged in a rear zone of the rotorcraft on either side of the anteroposterior midplane XOZ, and two fins arranged respectively on either side of the anteroposterior midplane XOZ, each of the two fins comprising a respective left/right bottom fin airfoil arranged below the horizontal stabilizer and a respective left/right top fin airfoil arranged above the horizontal stabilizer.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: April 27, 2021
    Assignees: AIRBUS HELICOPTERS, ONERA (OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES)
    Inventors: Raphael Fukari, Remy Huot, Paul Eglin, Jean-Paul Pinacho, Caroline Lienard, Itham Salah El Din
  • Pyrimidine compound as JAK kinase inhibitor
    Patent number: 10988470
    Abstract: The invention provides a compound of formula (I): or a pharmaceutically-acceptable salt thereof, that is an inhibitor of JAK kinases. The invention also provides pharmaceutical compositions comprising such compound, a crystalline form, methods of using such compound to treat inflammatory skin diseases and other diseases, and processes and intermediates useful for preparing such compound.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: April 27, 2021
    Assignee: Theravance Biopharma R&D IP, LLC
    Inventors: Jennifer Kozak, Ryan Hudson, Robert Murray McKinnell, Gary E. L. Brandt
  • Di-substituted maleic amide linker for antibody drug conjugating and preparation method and use thereof
    Patent number: 10987430
    Abstract: Provided in the present invention are a di-substituted maleic amide linker conjugated to an antibody and a preparation method and use thereof. In particular, the present invention conjugates a strongly cytotoxic active substance to a biomacromolecule through a class of new linkers. The class of linkers can selectively act simultaneously with disulphide chains, so as to greatly improve the substance homogeneity of a conjugate. The conjugate prepared by the linker of the present invention has a high inhibitory activity on a cell strain expressing the corresponding antigen. Also provided is a method for preparing the above-mentioned conjugate and the use.
    Type: Grant
    Filed: November 24, 2017
    Date of Patent: April 27, 2021
    Assignees: Mabwell (Shanghai) Bioscience Co., Ltd., Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd.
    Inventors: Jingkang Shen, Tao Meng, Lanping Ma, Xin Wang, Hongli Peng, Yongliang Zhang, Ting Yu, Lin Chen, Zhiyan Du, Ying Wang
  • FOOT FOR HOUSEHOLD APPLIANCE, AND HOUSEHOLD APPLIANCE
    Publication number: 20210116065
    Abstract: A foot for a household appliance includes a hydraulic plate, a sheath connected with the hydraulic plate, an adjustable foot arranged in the sheath and axially moveable relative to the sheath, and a device for communicating the flow of a hydraulic medium between at least two feet of the household appliance. An accommodating chamber is formed by the hydraulic plate, the sheath and the adjustable foot; the hydraulic medium is arranged in the accommodating chamber, and the hydraulic medium is compressed or expanded along with the change of pressure to drive the adjustable foot to move axially in the sheath for leveling. A control device for turning on/off the flow of the hydraulic medium is provided on the communicating device, a better leveling support effect is achieved by controlling the on/off of the communicating device.
    Type: Application
    Filed: March 23, 2018
    Publication date: April 22, 2021
    Applicants: QINGDAO HAIER WASHING MACHINE CO., LTD., QINGDAO HAIER SMART TECHNOLOGY R&D CO., LTD.
    Inventor: Zhiqiang ZHAO
  • WASHING BARREL OF A WASHING MACHINE, AND WASHING MACHINE
    Publication number: 20210115615
    Abstract: A washing barrel of a washing machine is rotatably installed within a cabinet of the washing machine as a structure for containing clothes and washing water. The washing barrel includes a drainage channel arranged on an outer side of the washing barrel for allowing water to be drained downwards, and an internal face of at least one side, away from the washing barrel, of the drainage channel gradually deviates away from a central axis of the washing barrel from top to bottom. The washing machine comprises the cabinet, the washing barrel, a mounting plate installed below a bottom of the washing barrel and configured to support the washing barrel, and the mounting plate is connected with the cabinet via a damping part.
    Type: Application
    Filed: April 27, 2018
    Publication date: April 22, 2021
    Applicants: QINGDAO HAIER WASHING MACHINE CO., LTD., QINGDAO HAIER SMART TECHNOLOGY R&D CO., LTD.
    Inventors: Xinghui HAO, Chunfeng LAO, Sheng XU, Yanfen LV, Di WU, Yimin LI
  • LAUNDRY METHOD
    Publication number: 20210115356
    Abstract: Method for softening knitted cotton, wherein knitted cotton is treated with an ancillary laundry composition comprising: a. Soil release polymer b. Silicone c. less than 4 w.t.% surfactant; and d. Water wherein the method comprises delivering the ancillary laundry composition into the wash or rise stage and comprises the steps of: a. Pouring a laundry product into a washing receptacle, a washing machine drawer, or a dosing shuttle b. Pouring the ancillary laundry composition on top of the laundry product. Use of the method for softening knitted cotton.
    Type: Application
    Filed: February 19, 2019
    Publication date: April 22, 2021
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Martin Charles CROSSMAN, Jonathan OSLER
  • TRIAZOLO[4,5-D] PYRAMIDINE DERIVATIVES AND THEIR USE AS PURINE RECEPTOR ANTAGONISTS
    Publication number: 20210115054
    Abstract: Compounds of formula (I) that are capable of acting as purine receptor antagonists, pharmaceutical compositions including the compounds, and methods of making the compounds, are disclosed. The compounds and compositions can be used in treating or preventing disorders related to purine receptor hyperfunctioning.
    Type: Application
    Filed: November 3, 2020
    Publication date: April 22, 2021
    Applicant: Vernalis (R&D) Limited
    Inventors: Samantha Jane Bamford, Roger John Gillespie, Richard Simon Todd
  • Securable Sampling Port for an Insulated Container
    Publication number: 20210114784
    Abstract: Apparatus and installation methods for sampling ports are disclosed. Sampling ports include a port housing and a lid assembly. The lid assembly is configured to sealably close against the port housing. Additionally, the lid assembly can be secured, such as with a lock, to the port housing. In one aspect, the port housing includes a sample mount arrangement configured to receive a sampling assembly. The sample mount arrangement defines a sampling channel and the port housing defines a sampling opening and a first securing mount. The lid assembly includes a latch arrangement and defines a second securing mount.
    Type: Application
    Filed: September 10, 2020
    Publication date: April 22, 2021
    Applicant: Quality Management Incorporated, d/b/a Qualitru Sampling Systems
    Inventor: Mark Jordan Schwab
  • COMBINATION THERAPIES FOR THE TREATMENT OF BREAST CANCER
    Publication number: 20210113537
    Abstract: Provided herein is a combination therapy useful for the treatment breast cancer. The combination comprises an ER-alpha inhibitor and a CDK 4/6 inhibitor.
    Type: Application
    Filed: March 16, 2018
    Publication date: April 22, 2021
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Craig D. KARR, Manav KORPAL, Nathalie RIOUX, Peter Gerard SMITH
  • CONTINUOUS, SOLVENT-FREE AND NON-ENZYMATIC PEPTIDE SYNTHESIS BY REACTIVE EXTRUSION
    Publication number: 20210115085
    Abstract: A continuous, solvent-free and non-enzymatic method for synthesizing a compound of formula (I): Ra-POLYPEP-Rc (I) wherein: POLYPEP is a poly-amino acid compound, Ra and Rc are as specified, the method including the steps of: a) feeding an extrusion reactor with (1) a compound of formula (II) Ra-PEPNt-Rg (II) wherein; PEPNt is a mono- or a poly-amino acid compound, Ra and Rg are as specified, and (2) a compound of formula (III) H-PEPCt-Rc (III) wherein: PEPCt is a mono- or a poly-amino acid compound, and Rc is as defined in the absence of any solvent, so that the compound of formula (II) and the compound of formula (III) react together for generating a compound of formula (I), and b) collecting the compound of formula (I) from the extrusion reactor.
    Type: Application
    Filed: February 12, 2019
    Publication date: April 22, 2021
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, ECOLE DES MINES D'ALES, ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS
    Inventors: Yves YEBOUE, Benjamin GALLARD, Nicolas LE MOIGNE, Frédéric LAMATY, Jean MARTINEZ, Thomas-Xavier METRO
  • METHODS OF MANUFACTURING A PHOTOVOLTAIC MODULE
    Publication number: 20210119073
    Abstract: Method of manufacturing a photovoltaic module comprising at least a first layer and a second layer affixed to each other by means of an encapsulant, said method comprising a lamination step wherein the encapsulant material comprises a silane-modified polyolefin having a melting point below 90° C., pigment particles and an additive comprising a cross-linking catalyst; and wherein in said lamination step heat and pressure are applied to the module, said heat being applied at a temperature between 60° C. and 125° C.
    Type: Application
    Filed: April 12, 2019
    Publication date: April 22, 2021
    Applicant: CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DÉVELOPPMENT
    Inventors: Hengyu LI, Jordi ESCARRE PALOU, Karin SÖDERSTRÖM, Xavier BULLIARD, Laure-Emmanuelle PERRET-AEBI, Christophe BALLIF
  • Optical system
    Patent number: 10983006
    Abstract: The present invention relates to an optical system including at least one objective lens (2) for receiving light from an object (1), an array of image forming elements (4) for generating multiple images of the object on an image sensor plane (SP) and a filter (F). The optical system is configured to form a real image of the filter on the array of image forming elements to filter the multiple images of the object, the filter being arranged with respect to the at least one objective lens so that a real image of the filter is formed on the array of image forming elements, and wherein the optical system is configured to be telecentric in the image plane of the filter.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: April 20, 2021
    Assignee: CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA—RECHERCHE ET DÉVELOPPEMENT
    Inventors: Ross Stanley, Amina Chebira, Liza Andrea Dunbar
  • 5-(pyridin-3-yl)oxazole allosteric modulators of the M4 muscarinic acetylcholine receptor
    Patent number: 10981902
    Abstract: The present invention is directed to 5-(pyridine-3-yl)oxaxole compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: April 20, 2021
    Assignees: Merck Sharp & Dohme Corp., Merck MSD (R&D) China Co., LTD.
    Inventors: Jianming Bao, Timothy J. Henderson, Chunsing Li, Michael Man-Chu Lo, Robert D. Mazzola, Jr., Meng Na, Michael T. Rudd, David M. Tellers, Ling Tong
  • Telescopic cleaning device
    Patent number: 10981545
    Abstract: A telescopic cleaning device is intended for projecting at least one cleaning and/or drying fluid onto a glass surface to be cleaned of a motor vehicle, such as an optical surface of an optical sensor of an optical detection system. The cleaning device includes at least one fluid distribution element, rendered movable, along an axis of elongation (X) and at the end of a movable piston between a retracted first position and an extended second position for cleaning and/or drying. The fluid distribution element comprises a distribution bar (4) inside which a fluid distribution channel (56) extends and the distribution bar is equipped with a heating device (60) integrated at least in part into the distribution bar in order to heat the fluid passing through said distribution channel.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: April 20, 2021
    Assignee: Valeo Systèmes d'Essuyage
    Inventors: Philippe Picot, Jordan Vieille, Sébastien Rollet, Grégory Kolanowski, Giuseppe Grasso, Xavier Bousset, Maxime Baudouin
  • Proteins of the WNT signaling pathway and uses thereof in the diagnostic and treatment of hypopigmentation disorders
    Patent number: 10983134
    Abstract: The present invention relates to the identification of proteins of the WNT signaling pathway as therapeutic targets of pigmentation disorder and as biomarkers of pigmentation status. The invention in particular relates to products and methods for treating a hypopigmentation disorder. The invention also relates to products and methods for detecting, diagnosing, staging or monitoring the course of hypopigmentation disorder and is particularly suited for human subjects.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: April 20, 2021
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ CÔTE D'AZUR, CHU DE NICE
    Inventors: Thierry Passeron, Florence Joly
  • Use of coconut water as extraction solvent
    Patent number: 10981084
    Abstract: The present invention relates to the use of coconut water as extraction solvent, to extraction methods using coconut water and extracts obtained by extraction with coconut water.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: April 20, 2021
    Assignees: BASF Beauty Care Solutions France SAS, Universite d'Avignon et des Pays du Vaucluse
    Inventors: Caroline Makerri, Philippe Moser, Farid Chemat, Sandrine Perino