Abstract: A cosmetic method of reducing perspiration comprising the topical application of a composition comprising a non-pore blocking antiperspirant agent of general formula (I): Ar—CHaCHa—X wherein Ar is an aryl group, a is 1 or 2, and X is a sub-structure of formula CH(OH)—Y or CO.Z, wherein Y is a C1-C10 hydroxyalkyl group and Z is a C1-C10 hydroxyalkyl group or a C1-C10 oxyalkyl group.

Abstract: In one aspect, the invention relates to a compound of the structure: or a pharmaceutically acceptable salt thereof, and a crystalline form of this compound, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this compound; methods of using this compound; and processes for preparing this compound.

Abstract: A cooler cabinet comprises: a storage compartment (130) for food or beverage products (130); a dispensing mechanism (143) for dispensing the food or beverage products (144) from the storage compartment without opening the storage compartment to ambient air; a water-retaining material (120) outside the storage compartment but in contact with it; an air channel (111) in contact with the water-retaining material; and means (114) for moving air through the air channel such that the air increases the rate of evaporation of water from the water-retaining material. It thereby withdraws heat from the water-retaining material and causes cooling of the interior of the cabinet, including the food or beverage products.

Abstract: A module for mounting within a ceiling panel assembly. The module includes an upper mounting frame that includes a main body portion that defines a central opening, a lower mounting frame that is at least partially received in the central opening of the upper mounting frame, and a latch assembly. The main body portion of the upper mounting frame includes a flange extending outwardly therefrom. The lower mounting frame is pivotable with respect to the upper mounting frame between a first position and a second position. The latch assembly is associated with a first end of the upper mounting frame and the lower mounting frame. When the latch assembly is released the lower mounting frame pivots from the first position to the second position.

Abstract: The invention relates to a multibeam source for a multibeam antenna, the source comprising a plurality of identical basic sources, such that the basic sources are combined into identical subnetworks around a central basic source, each subnetwork forming a beam, and such that two adjacent subnetworks comprise at least one common basic source, wherein the source includes: a supply and polarization stage for supplying power to the central basic sources and polarizing the electromagnetic field at the accesses of the central basic sources; and a stage for distributing the power from the central basic sources among the basic sources of the corresponding subnetwork and those common to a plurality of subnetworks according to a predetermined amplitude law.

Abstract: The present invention provides a cationic lipid which can be used for nucleic acid delivery to a cytoplasm and which is possible to solve the problem of physical stability of a lipid complex. This cationic lipid is a compound represented by the general formula (3) or a pharmaceutically acceptable salt thereof: wherein, L is an alkyl having 7-12 carbon atoms or an alkenyl having 7-12 carbon atoms, R is an alkyl having 1-2 carbon atoms, and n1 and n2 are independently an integer of 1-3.

Abstract: Herein disclosed is a method of generating products from microorganisms, comprising super-saturating a liquid medium with a gas consumable by the microorganisms in a high shear device operating at a shear rate of greater than 1,000,000 s?1 to produce a gas-super-saturated (GSS) medium, wherein the GSS medium maintains a GSS level for at least 10 minutes; feeding the GSS medium to microorganisms; allowing the microorganisms to grow by consuming the gas and generate products via photosynthesis or chemosynthesis; and recovering the products. In an embodiment, the microorganisms are genetically modified. In an embodiment, the microorganisms include bacteria, protozoa, algae, or fungi, or a combination thereof. In an embodiment, the gas consumable by the microorganisms is selected from the group consisting of carbon dioxide, nitrogen, air, oxygen, methane, and combinations thereof. A suitable system is also discussed in this disclosure.

Abstract: A problem graph having one or more odd cycles is embedded in a quantum processor. The quantum processor includes a plurality of qubits and coupling devices, each coupling device operable to provide controllable communicative coupling between a respective pair of the plurality of qubits to form an interconnected topology. Embedding may, for example, be realized by mapping each vertex of the problem graph to a respective single qubit; mapping each edge of the problem graph to a respective single coupling device, where for pairs of qubits, each qubit of the pair is mapped to a respective pair of vertices. The problem graph may include one or more sub-graphs, one or more of the sub-graphs being a bipartite K3,3 graph.

Abstract: In one aspect, the invention relates to compounds having the formula: where X, Ra, Rb, R2, and R7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.

Abstract: The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.

Abstract: Systems and methods formulate problems for solving by a quantum processor using hardware graph decomposition. A decomposition of a primal graph may be built in a first stage based on a hardware specific graph, and refined in a second stage by, for example, removing vertices from the decomposition. The hardware specific graph may be a graph that is specific to a piece of hardware, for instance a quantum processor comprising a plurality of qubits and couplers operable to communicatively couple pairs of qubits.

Abstract: Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4?-(morpholinomethyl)-[1,1?-biphenyl]-3-carboxamide hydrobromide. Also provided herein is a particular polymorph form of this compound.

Abstract: In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.

Abstract: The invention relates to an arrangement (20) for determining the angular position of a shaft (11) of an electric motor (10), in particular of a shaft (11) of a windscreen wiper motor (100), with a magnet element arrangement, connected with the shaft (11), and several magnetic field sensors (26, 27, 28), wherein the angular position of the shaft (11) is inferred from the different signals of the magnetic field sensors (26, 27, 28). Provision is made, according to the invention, for the magnet element arrangement to comprise at least one magnet element, preferably several separate magnet elements (21, 22, 23), which are arranged one behind the other in the longitudinal direction of the shaft (11), and for the magnetic field sensors (26, 27, 28) to be arranged on a printed circuit board (30) which is arranged at a slight distance from the shaft (11), such that the magnetic fields of the magnet elements (21, 22, 23) are able to be determined by the magnetic field sensors (26, 27, 28).

Abstract: An anhydrous antiperspirant aerosol composition comprising a particulate antiperspirant active system, suspending agent, carrier oil, and liquefied propellant gas, characterised in that the particulate antiperspirant active system comprises an aluminium sesquichlorohyrate of formula AI2OH4.4CI1.6 to AI2OH4.9CI1.1 activated with a water soluble calcium salt.

Abstract: The present invention relates to a method for treating a Leber congenital amaurosis in a patient harbouring the mutation c.2991+1655 A>G in the CEP290 gene, comprising the step of administering to said patient at least one antisense oligonucleotide complementary to nucleic acid sequence that is necessary for preventing splicing of the cryptic exon inserted into the mutant c.

Abstract: Packaging container having a chamber wherein the chamber comprises a plurality of corresponding products (1) sized such that a number of such products essentially completely fills the chamber, the packaging comprising at least one removable portion (4, 6) dimensioned such that the at least one removable portion (4, 6) can be removed from the packaging, rearranged to adopt an expanded form and placed within the chamber, having the effect of reducing the volume of the chamber available for the products (1) by n times the volume of a contained product (1), where n is an integer, whilst retaining the feature that a number of such products (1) essentially completely fills the chamber.

Abstract: A novel miniaturized and highly automated method for the controlled printing of large arrays of nano- to femtoliter droplets is presented by actively transporting mother droplets over hydrophilic-in-hydrophobic micropatches. The proposed technology consists of single plate or double-plate devices where mother droplets can be actuated and hydrophilic-in-hydrophobic micropatches on one or both plates of the device where nano- to femtoliter droplets are printed. Due to the selective wettability of the more wettable hydrophilic micropatches in a hydrophobic matrix, large nano- to femtoliter droplet arrays are created when mother droplets are transported over these arrays. The parent droplets can be moved by different droplet actuation principles, for example, by using the principle of electrowetting-on-dielectric droplet actuation. We propose another method that uses two plates that are placed on top of each other while being separated by a spacer.

Abstract: A light emitting apparatus is provided. The light emitting apparatus includes a light source which emits laser light. A first light guide, which is flexible, extends from the light source for guiding the laser light emitted by the light source. A second light guide, which has a fixed shape, is connected to the first light guide for guiding the laser light emitted by the light source. A body holds the second light guide and sends out, to an outside of the body, light based on the laser light guided by the first light guide and the second light guide.