Abstract: The invention provides methods for predicting the efficacy of eribulin, an analog thereof, or a pharmaceutically acceptable salt thereof (e.g., eribulin mesylate), in the treatment of a subject suffering from breast cancer by determining the level of particular biomarkers in a sample derived from the subject.

Abstract: A rope grab for a vertical fall protection system is provided. The rope grab includes a housing with an elongated member passage. The elongated member passage is configured to receive an elongated member. A locking cam is pivotally coupled to the housing and selectively engages an elongated member received in the elongated member passage. A cam spring is coupled between the housing and the locking cam to provide a relatively slight biasing force on the locking cam in a direction towards an elongated member received in the elongated member passage. A locking arm, pivotally coupled to the housing, has a first end that is configured to be coupled to a safety harness of a user and a second end that selectively engages the locking cam to lock the locking cam on an elongated member in the elongated member passage during a fall event.

Abstract: A nose support assembly for a spectacle frame, includes two nose support elements (3), known as nose pads, and, for each nose pad, a mounting element (2) for the nose pad, known as the nose pad holder. Each nose pad (3) and the corresponding nose pad holder (2) have connecting elements (1) for connecting one to the other, the connecting elements being designed to allow the nose pad (3) to move angularly with respect to the nose pad holder (2). A frame equipped with such a nose support assembly is also described.

Abstract: The present document describes a device and method for synchronizing a motion signal corresponding to a media content with a media signal for the media content, the motion signal being for controlling a motion feedback system. The method comprises: receiving a portion of the media signal; obtaining a fingerprint corresponding to the received portion of the media signal; from reference fingerprints associated with time positions of at least one reference media content, identifying a reference time position of the media content corresponding to the obtained fingerprint; obtaining the motion signal associated with the identified reference time position of the media content; and outputting the motion signal synchronized with the media signal using the identified reference time position of the media content for controlling the motion feedback system.

Abstract: A composition includes: a continuous liquid phase including an acrylic monomer and an epoxy monomer; and a dispersed nanoparticulate including ZrO2 modified with an acrylic silane; and wherein the composition is transparent to visible light when coated on a lens. In addition, a method including the steps of: mixing an acrylic silane and a methanol-based ZrO2 sol to create a methanol-based silane-modified ZrO2 sol; then mixing at least an acrylic monomer, an epoxy monomer, and the methanol-based silane-modified ZrO2 sol to obtain the composition. The composition can be adapted for coating and curing onto another substrate, such as an ophthalmic lens.

Abstract: Method for the manufacture of an optical article comprising the following steps: —providing a substrate having two main faces and bearing —OH functions on at least one of its faces, —successively exposing in this order one face of the substrate bearing —OH functions to at least 3 distinct materials named M1, M2, M3 and optionally material M4 in a vacuum chamber under conditions resulting in the deposit of those materials on the surface of the substrate, and wherein: —M1 is a substituted silane comprising at least one function X1 directly bonded to a Si atom of the substituted silane, wherein the Si—X1 group is capable of forming a covalent bond with a OH group of the substrate, X1 being preferably a hydrolysable group (such a —NH2 group) or a —OH group directly bonded to the silicon atom and comprising at least one fluorine containing group, —M2 is a substituted silane of number average molecular weight inferior or equal to 900 g/mol comprising at least one function X2 directly bonded to a silicon atom of sai

Abstract: The invention relates to a ready-to-drink proteinaceous beverage having a pH of 3-7.5 and a G? from 0.01 Pa to 10 kPa at 20° C., said beverage comprising: •0.1-10 wt. % of vegetable protein; •0.01-2.0 wt. of amorphous cellulose microfibrils originating from defibrillated primary cell wall material, said amorphous cellulose microfibrils having a length of at least 0.5 ?m, a thickness of less than 50 nm, and having an average degree of crystallinity of less than 50%; •0-20 wt. % fat; and •at least 78 wt. % of water, wherein the beverages contains no dairy protein. This proteinaceous beverage combines excellent mouthfeel characteristics with high stability and desirable rheological properties.

Abstract: The present invention is directed to six membered heteroaryl benzamide compounds of formula (I), which are tropomyosin-related kinase (Trk) family protein pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.

Abstract: A vehicle seat includes a pair of side frames and a load sensor. The load sensor is provided at a lower portion of the side frame or below the side frame. The vehicle seat further includes a supporting member which is connected to the side frame and which supports a seated person. The supporting member includes a seat portion which receives a weight of a seated person. The seat portion is provided below the load sensor.

Abstract: The invention relates to a connection device B for mechanically linking a wiper blade A to a windscreen wiper drive arm C, C? of a motor vehicle, said connection device (B) includes a connector 2 designed to be rigidly attached to the wiper blade A and an adaptor 3 designed to connect the connector 2 to an end part 5, 5? of the drive arm C, C?, in which the connector 2 includes at least one hole 24 of circular section through which the axis of rotation Y between the wiper blade A and the drive arm C, C? passes, the hole 24 in the connector being delimited by at least one flank 23 of the connector 2 and the adaptor 3 having at least one through-seat 40, 40? into which at least a portion of the flank 23 extends.

Abstract: Provided is an audio system in which an audio signal to be heard can be automatically set to an appropriate volume or sound quality. The audio system is provided with: a mobile terminal device provided with a microphone unit that collects surrounding sound waves, and a transmission unit that, on the basis of the sound waves collected by the microphone unit, sets the volume or sound quality of an audio signal to be amplified by an audio device, and transmits the set audio signal volume or sound quality information to the audio device; and an audio device provided with an amplification unit that amplifies the audio signal, a control unit that adjusts the audio signal volume or sound quality by means of the amplifier, and a receiving unit that receives the audio signal volume or sound quality setting information from the mobile terminal device.

Abstract: A web-page or customer interface, that enables a business to increase their customer satisfaction levels, etc. based on the business' improved capability to predict the wants and needs of their customers as a result of it using such an interface to assess the personalities of their customers, includes: (a) personality traits (b) images, including animated, to which are assigned ranked personality traits based on the psychological content of the respective images, (c) an image viewer adapted to present to a customer these images so as to identify with which of these images the customer elects to be associated, (d) personality types into which a customer is categorized, and wherein each of these personality types is differentiated by the specific set of personality traits associated with it, and (e) an algorithm adapted to categorize one into a personality types.

Abstract: A method of determining at least one behavioral parameter of a wearer for designing an ophthalmic eyeglass lens includes: a) acquiring a first data set from a first representation of the head of the wearer in three dimensions; b) determining the relative position in space of at least three particular points of the head based on the data set; c) acquiring a second data set from a second representation of the head in a natural posture, including at least one image of each of the three particular points; d) identifying the image of each of the particular points from step b) on the representation of step c); e) deducing information relating to the position and/or to the orientation of the head of the wearer during the determination of the second representation from this identification; and f) determining the behavioural parameter of the wearer based on the information from step e).

Abstract: A packaging block that includes a body section having a aperture defined therein. A hinge defines a first portion of the body section and a second portion of the body section. The first portion is rotatably coupled to the second portion via the hinge. A plurality of selectively removable sections are removably coupled to the body section. The aperture receives at least a portion of an article to facilitate securement of the article during packaging and transport.

Abstract: This disclosure provides a system and method for limiting a swing angle of a jib crane, the jib crane having a jib rotatably mounted to a mast. The device can have a collar having a collar height and a collar width, the collar being configured to be fit to the mast at a stop height. The device can also have one or more stopping tabs enagagable with the collar and configured to be positioned on the collar at one or more points about a circumference of the mast. The stop height can place the one or more stopping tabs in a position coincident with the jib to interfere with the swing angle of the jib. The method can use the device to limit the angle through which the jibe crane can swing unimpeded.

Abstract: An optical semiconductor device comprises, on a substrate, a fin of diamond-cubic semiconductor material and, at the base of the fin, a slab of that semiconductor material, in a diamond-hexagonal structure, that extends over the full width of the fin, the slab being configured as an optically active material. This semiconductor material can contain silicon. A method for manufacturing the optical semiconductor device comprises annealing the sidewalls of the fin, thereby inducing a stress gradient along the width of the fin.

Abstract: In one aspect, fabricating a superconductive integrated circuit with a Josephson junction includes applying oxygen or nitrogen to at least part of a structure formed from an outer superconductive layer to passivate an artifact, if any, left from removing the portion of the outer superconductive layer. In another aspect, a first superconductive layer is deposited, a second superconductive layer is deposited on the first superconductive layer, an oxide layer is formed on the first superconductive layer, a dielectric layer is deposited on the oxide layer, a portion of the dielectric layer is removed, a first portion of the oxide layer is removed, a second oxide portion is formed in place of the first portion of the oxide layer, and a third superconductive layer is deposited on the dielectric layer and the second oxide portion.

Abstract: The AC-DC power booster includes an electromagnetic interference (EMI) filter circuit that is included to convert alternating current (AC) power from among applied AC power and direct current (DC) power, to DC power to be output; a power factor correction (PFC) circuit that is connected to the EMI filter circuit and stabilizes an output voltage; and a switching mode power supply (SMPS) circuit that is connected to the PFC circuit and is capable of generating AC and DC power at the same time; a maximum power point tracking (MPPT) circuit that applies the voltage output from the SMPS circuit between a drain and a source of a switching device; a battery that is charged by receiving power from a solar light energy source connected to the MPPT circuit; and an inverter that operates an AC home appliance with the power received in the battery.

Abstract: The present system and method relate to a system for performing a multiplication. The system is arranged for receiving a first data value, and comprises means for calculating at run time a set of instructions for performing a multiplication using the first data value, storage means for storing the set of instructions calculated at run time, multiplication means arranged for receiving a second data value and at least one instruction from the stored set of instructions and arranged for performing multiplication of the first and the second data values using the at least one instruction.