Abstract: A press-type dispensing container that includes an outer case that includes a hollow tube portion and a compressible region; and an inner member including a support portion that is configured to support a personal care product, wherein the inner component is contained within the outer case and is configured to migrate towards the shaft portion when the compressible region of the outer case is compressed by a user is presented.

Abstract: The invention relates to a compound which inhibits the importation of chloride into neurons or a compound which improve the outflow of chloride from neurons for use in the treatment of autism in a baby or a fetus in need thereof.

Abstract: In one aspect, the invention relates to compounds having the formula: where R1, R2a, R2b, R3-R6, a, b, Z, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.

Abstract: The present invention relates to a multi-compartment water soluble laundry detergent capsule formed from water-soluble polyvinyl alcohol film and a method of preparing a component of the capsule wherein the capsule comprises: i) a first compartment for holding solid material comprising HEDP sequestrant or a salt thereof; and ii) a second compartment for holding liquid material comprising an aqueous liquid laundry detergent comprising: surfactant, enzymes and hydrotrope wherein: a) the HEDP is present in the capsule in the form of loose packed granules and comprises at least 25% by weight of the solid material in the first compartment; and b) wherein the HEDP further comprises 1.5% by weight or less of fines particles with a particle of less than 180 microns and 3.0% by weight or less of fines particles with a particle size of less than 355 microns.

Abstract: The invention relates to a wiper device (10) for cleaning vehicle windows, with a wiper arm (11) and with a wiper blade (12) able to be fastened on the wiper arm (11), with a cleaning device (25), having at least one spray nozzle (44, 45), for spraying a washing fluid, wherein the at least one spray nozzle (44, 45) is arranged in the region of the free end of the wiper arm (11) and is connected directly therewith, and with a fastening device (35) for connecting the wiper blade (12) with the wiper arm (11), wherein the wiper arm (11) has a mount (28), having an at least substantially U-shaped cross section, with two parallel side wails (17, 18) for the fastening device (35) of the wiper blade (12), and wherein the cleaning device (25) is constructed on a component (27) which is separate from the fastening device (35) for the wiper blade (12).

Abstract: An integrated dehumidification method that combines boundary layer control with mainstream disturbance enhanced heat exchange comprises heat transfer enhancement units; within each unit, a periodic vortex is formed along a extending direction of the flow channel by setting a boundary layer flow control device adjacent to a boundary layer, thus realizing cleaning of the cold and hot side walls, as a result it destroys the boundary layer blocking heat transfer, and helps to rapidly transfer a cold and heat energy generated on the cold and hot side walls to a flow mainstream channel; a mainstream disturbance device is set on the flow mainstream channel to form an axial vortex at the back of the device to cooperate with a stream emanating from the boundary layer, thus rapidly transferring the cold and heat energy from the boundary layer to a whole field to form an even temperature field.

Abstract: The invention relates to a wiper device (100) for cleaning vehicle windows, with a wiper arm (10; 10a-10d) and a wiper blade (1) able to be fastened to the wiper arm (10; 10a-10d), with a cleaning arrangement (40; 40a-40d) having at least one first spray nozzle (42, 43) for spraying a washing fluid, wherein the cleaning arrangement (40; 40a-40d) is connected directly with the wiper arm (10; 10a-10d), and with a fastening arrangement (2) for connecting the wiper blade (1) with the wiper arm (10; 10a-10d), wherein the cleaning arrangement (40; 40a-40d) is constructed as a separate component from the fastening arrangement (2) for the wiper blade (1).

Abstract: The invention relates to a wiper device (100) for cleaning vehicle windows, with a wiper arm (10a-10d) and a wiper blade (1) able to be fastened to the wiper arm (10a-10d), with a cleaning arrangement (40a-40d) having at least one first spray nozzle (42, 43) for spraying a washing fluid, wherein the cleaning arrangement (40a-40d) is connected directly with the wiper arm (10a-10d), and with a fastening arrangement (2) for connecting the wiper blade (1) with the wiper arm (10a-10d), wherein the wiper arm (10a-10d) has a mount (21), having an at least substantially U-shaped cross-section, with two parallel side walls (19, 20), and wherein the cleaning arrangement (40a-40d) is constructed as a separate component from the fastening arrangement (2) for the wiper blade (1).

Abstract: The invention relates to a wiper device (100) for cleaning vehicle windows, with a wiper arm (10) and with a wiper blade (1), which is fastened on the wiper arm (10) by means of a fastening arrangement (2), and with a cleaning arrangement (40), which has at least one spray nozzle (42, 43, 47, 48) for a cleaning fluid, wherein the cleaning arrangement (40) is directly connected with the wiper arm (10), and wherein the fastening arrangement (2) is constructed as a separate element from the cleaning arrangement (40). It is provided according to the invention that the cleaning arrangement (40) is constructed to hold the fastening arrangement (2) for the wiper blade (1), and that on the fastening arrangement (2) and the cleaning arrangement (40) first and second guide means (65, 66), cooperating with one another, are provided, which guide the fastening arrangement (2) on mounting on the cleaning arrangement (40) between an initial position (80) and a final position (81).

Abstract: The invention relates to a wiper arm (10; 10a-10d) for cleaning a vehicle window, with a carrier element (11), which is able to be connected at a first end region at least indirectly with a drive shaft and at another end region with a wiper blade (1), and with an additional element (30) connected with the carrier element (11), which additional element (30) extends in longitudinal direction of the wiper arm. It is provided according to the invention that the additional element (30) has at least one air guide section (166, 167), extending in longitudinal direction of the wiper arm (10; 10a-10d), which at least one air guide section (166, 167) projects beyond the underside (168) of the carrier element (11) on the side facing the vehicle window.

Abstract: The present invention relates to a method for endotoxin removal from a sample comprising the following steps: combining the sample comprising one or more target molecule(s) with a chromatography media comprising beads having an inner porous core functionalized with ligands capable of binding endotoxin and an outer porous layer without functional groups and a pore size small enough to exclude the target molecule from the inner core; and collecting the sample from the media, wherein the sample comprises an endotoxin level which is at least 75% less, preferably 90% less, than before the removal and the yield of the target molecule is at least 75%.

Abstract: The invention relates to a wiper arm head (14) for a wiper arm rod (11), with a first end region (178), which has an opening (15) for receiving a drive shaft, and a second end region (179) for the pivotable fastening of the wiper arm rod (11), and with means for directing at least one hose (31, 32) carrying a cleaning fluid. It is provided according to the invention that the means has a feedthrough (181, 182), which leads the hose (31, 32) from an upper side (187) in the direction of an underside (188) of the wiper arm head (14).

Abstract: The invention relates to a cleaning arrangement (40) for the cleaning of vehicle windows, wherein the cleaning arrangement (40) has a base body (131) with at least one spray opening (42, 43), wherein the base body (131) is able to be connected to a wiper arm (10), and wherein the base body (131) has a supply connection (51) for a cleaning fluid, which supply connection (51) is hydraulically connected to the spray opening (42, 43) via a connecting duct (121). According to the invention, it is provided that a feed connection (141) branches off from the connecting duct (121), which feed connection (141) opens in a connecting chamber (140) of the base body (131), and that the connecting chamber (140) is able to be closed by means of a closure cap (95).

Abstract: The invention relates to a wiper device (100) for vehicle windows, with a wiper arm (10) and with a wiper blade (1), which is fastened pivotably on the wiper arm (10) by means of a fastening arrangement (2), and with a cleaning arrangement (40), which has at least one spray nozzle (42, 43) for a cleaning fluid, whereby the cleaning arrangement (40) is arranged at least partially within the wiper arm (10). It is provided according to the invention that the fastening arrangement (2) of the wiper blade (1) is arranged at least partially within the cleaning arrangement (40), and that the cleaning arrangement (40) has at least one recess (118, 119) for the at least partial receiving of a part (116) of the fastening arrangement (2) which is movable in relation to the cleaning arrangement (40) on pivoting.

Abstract: The invention relates to a cleaning arrangement (40; 40a-40d) for cleaning a vehicle window, with a wiper arm (10; 10a-10d) and with at least one hose (31, 32), fastened to the wiper arm (10; 10a-10d), for a cleaning fluid. It is provided according to the invention that the hose (31, 32) is connected by a form-fitting fastening, secure with regard to rotation angle, at least indirectly to the wiper arm (10; 10a-10d).

Abstract: This invention relates to method of diagnosing the presence and/or severity of a liver pathology and/or of monitoring the effectiveness of a curative treatment against a liver pathology in an individual, leading to a score, comprising the combination, of at least one blood test and of at least one data issued from a physical method of diagnosing liver fibrosis, said data being selected from the group consisting of medical imaging data and clinical measurements, said combination being performed through a mathematical function. This invention also relates to a method wherein the combination through a mathematical function, of at least one blood test and of at least one data issued from a physical method of diagnosing liver fibrosis, is performed at least twice and the at least two resulting scores are combined in an algorithm based on the diagnostic reliable intervals.

Abstract: An example holder apparatus includes a body portion and a gate portion. The body portion includes a first sidewall and a second sidewall that opposes the first sidewall to form a channel therebetween. The gate portion is, at least in use, physically coupled to the second sidewall of the body portion and movable between an open configuration and a closed configuration. The gate portion includes a cross-channel member that, when the gate portion is in the closed configuration, extends across an entire width of the channel to physically engage a channel-facing surface of the first sidewall or a portion of an object held between the cross-channel member and the channel-facing surface of the first sidewall. An example kit for a holder apparatus includes a body portion and a gate portion. The gate portion is selectively physically coupleable to the body portion via a snap fit.

Abstract: A connector comprises a base, a gate, and a locking mechanism. The base forms an opening. The gate is slidably operatively connected to the base and spans the opening. The locking member has an engaging position and a releasing position. The engaging position secures the gate to the base, and the releasing position allows the gate to be moved relative to the base.

Abstract: A device for measuring the objective ocular refraction of a patient for a plurality of visual ranges, which includes a variable proximity optical sight system capable of selectively generating a first target and a second target and an image-capturing device having an optical measurement axis intended for being aligned with a line of sight of the patient, the image-capturing device being capable of capturing a first ocular refraction image when the first target is activated and a second ocular refraction image when the second target is activated. The image-capturing device and the optical sight system are arranged such that the optical measurement axis and the optical sight axis are arranged such that the optical measurement axis and the optical sight axis are contained in a single plane and the optical measurement axis is tilted at an angle alpha between +5 degrees and +85 degrees relative to the horizontal.

Abstract: The invention, which relates to a miniaturizable plasma thruster, consists of: —igniting the plasma by microhollow cathode discharge close to the outlet and inside the means for injecting the propellant gas, said injection means being magnetic and comprising a tip at the downstream end thereof; —bringing the electrons of the magnetized plasma into gyromagnetic rotation, at the outlet end of said injection means; —sustaining the plasma by means of Electron Cyclotron Resonance (ECR), said injection means being metal and being used as an antenna for electromagnetic (EM) emission, the volume of ECR plasma at the outlet of said injection means being used as a resonant cavity of the EM wave; —accelerating the plasma in a magnetic nozzle by diamagnetic force, the ejected plasma being electrically neutral.