Abstract: An animal cleaning tool for cleaning and maintaining a hygiene of an animal is provided. An animal cleaning tool includes a top housing portion and a bottom plate surface, the bottom plate surface having a set of brushing elements that are spaced apart and protrude outwardly from the bottom plate. The top housing portion includes an air supply conduit and a cleaning agent supply conduit adapted to be disposed within an interior of the top housing portion of the animal cleaning tool, whereby the air supply conduit is configured to distribute air and the cleaning agent supply conduit is configured to distribute cleaning agent. A method for using an animal cleaning tool is provided that includes dispensing the cleaning agent as an atomized spray of particles onto a surface of the animal using the animal cleaning tool.

Abstract: A flooring system for a vehicle having a corrugated floor comprises a plurality of flooring panels supported at their undersides by two or more registration members having locating members and other features for aligning the flooring panels vertically, laterally, and longitudinally. The flooring panels each have at least one longitudinally aligned load-bearing structure, such as in integrated track or a universal channel configured to receive a flanged track, filler material, or both. The registration members may have depending support members configured to engage in the valleys of the corrugated vehicle floor.

Abstract: The present invention relates to a composition in the form of an oil-in-water emulsion, preferably a mayonnaise-type emulsion, containing ground white or yellow mustard seed. This way the amount of oil in the emulsion can be reduced, while keeping the structure of full-fat mayo, without using large amounts of thickeners or water-structurants. Moreover the invention relates to the use of ground white or yellow mustard seed as an ingredient of the emulsion to reduce the concentration of oil in the emulsion.

Abstract: The disclosure relates to a method for verifying a printed pattern. In an example embodiment, the method includes defining sectors of at least a portion of the features in the reference pattern, determining a contour of the printed pattern, and superimposing the contour of the printed pattern on the reference pattern. The method also includes determining surface areas of sectors of the printed pattern that correspond to the sectors of the reference pattern and calculating one or more parameters as a function of at least one of the surface areas, the parameters being related to a single sector or to multiple sectors. The method additionally includes evaluating the parameters with respect to a reference value.

Abstract: The inventors have observed that aqueous mustard seed extract appears to be cytotoxic to fibroblast cells. The cytotoxicity of the aqueous mustard seed extract appears to abate when the extract is heat treated at 120° C. for 15 minutes. The heat treated aqueous mustard seed extract when combined with exogenous myrosinase is not cytotoxic but can induce a modest increase in HO-1 content in cultured fibroblasts and thus would be expected to be useful in a topical composition for treating/preventing itchy skin, particularly the scalp. This invention thus relates to the provision of a topical composition for treating/preventing itchy skin, particularly the scalp.

Abstract: The invention relates to bars which provide specific combinations and amounts of nonionic polymer, polyol, short chain fatty acid and solid particles. These specific combinations provide both improved sensory and improved fragrance delivery.

Abstract: A wiper blade for cleaning a vehicle windscreen having a carrier element configured to hold a wiper rubber is disclosed. A wiper blade adapter, fixed to the carrier element, is configured to detachably connect the wiper blade to a wiper arm. The wiper arm includes a wiper arm adapter disposed on the wiper arm that is oriented along a longitudinal extension of the wiper arm in an assembly direction. The wiper blade adapter includes a first adapter section attached to the carrier element, a second adapter section configured to directly connect to the wiper arm adapter, and indirectly connect to the wiper arm via the wiper arm adapter, a joint that articulates the first adapter section and the second adapter section, and an electrical connecting element having an electrical contact configured to reversibly establish an electrical connection between a heating element and a current supply disposed on the wiper arm.

Abstract: Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with various aspects of cancer. Panels or signature sets of proteins useful in the detection, diagnosis and treatment of cancers as well as monitoring therapeutic progress in a cancer patient are provided herein along with methods for their detection and for their use in targeting imaging and/or therapeutic agents to the tumors via binding to the specified proteins. The proteins were identified using proteomics analyses of tissue samples taken from cancer patients. In certain aspects the proteins are particularly useful in colon cancer patients.

Abstract: The present invention relates to extruded soap bars having improved transparency. Specifically, by balancing the amounts of C16 (palmitic acid) and C18 (stearic acid) fatty acids to have a ratio in the final bar of 1, substantially improved transparency is unexpectedly obtained.

Abstract: The present invention provides a neural stem cell having increased passage ability and a method for manufacturing a neural stem cell having increased passage ability. A neural stem cell in which the N-type calcium channel gene is knocked out or the influx of Ca2+ via the N-type calcium channel is substantially absent can be passaged for at least 4 generations and maintains the differentiation potential into a nerve cell even after passage for 4 generations.

Abstract: A pull handle (1) for a lock of a vehicle door or lift gate featuring a pull handle housing (1a) having a bearing part (2) and a handle part (3) connected so as to swivel around a swivel axis between non-actuated and actuated positions. An actuation mechanism (4) mounted in the pull handle housing (1a) and can be actuated by the handle part (3). A coupling element (56) mounted in the pull handle housing (1a) couples with external lock elements. A locking mechanism (5) locks and unlocks the actuation mechanism (4). The coupling element is displaceable in the bearing part along an actuation axis (209), perpendicular to the swivel axis, and connected to the handle part (3) for linear movement in the actuation direction (204) parallel to the actuation axis (209).

Abstract: The present invention relates to compound of formula I, II, III, or IV, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof, Formulas (I), (II), (III) and (IV) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are as defined in the claim 1 or as described in detail in the description of the invention, and to the use of said compounds to treat or prevent proliferative disorders and their use to manufacture a medicine to treat or prevent proliferative disorders, particularly cancer such as leukemia. The present invention also relates to pharmaceutical compositions of said compounds and the use of said pharmaceutical compositions to treat or prevent proliferative disorders. The present invention further relates to the use of said compounds as biologically active ingredients, more specifically as medicaments for the treatment of proliferative disorders and pathologic conditions such as, but not limited to, cancer such as leukemia.

Abstract: A safety rail for a flatbed trailer including a track that is engaged adjacent an edge of the flatbed trailer and a plurality of post holder assemblies engaged with the track. The post holder assemblies are selectively movable along the track between an operational position and a storage position. When the safety rail is in the operational position, the post holder assemblies are spaced a distance apart from each other and, when in the storage position, the post holder assemblies are in tongue-and-groove interlocking engagement with each other. A post is engaged with each of the post holder assemblies and a cable is threaded through an aperture in each of the posts. The post holder assemblies include one or more wheels which engage the track and roll therealong as the safety rail is moved between the operational and storage positions.

Abstract: The present invention relates to the amyloid beta peptide (A?) and more specifically to antibodies binding to A? protofibrils and their use in therapy and/or prophylactic treatment of Alzheimer's disease and other disorders associated with A? protein aggregation. Further the invention may relate to diagnosis of such diseases as well as monitoring of disease progression by use of the antibodies of the invention. Further, the invention may relate to veterinary use of the antibodies of the invention.

Abstract: The present invention provides a salt of (S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[4,3-c]quinolin-4(5H)-one and an acid selected from the group consisting of hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid, malonic acid, maleic acid, tartaric acid, methanesulfonic acid, benzenesulfonic acid and toluenesulfonic acid; or a crystal thereof with a potential to be used as drug substance in pharmaceuticals.

Abstract: A sintered product made from a starting batch containing 5 to 50% zircon and having the following average chemical composition, in weight percentages on the basis of the oxides and for a total of 100%: silica and zirconia, the zirconia content (ZrO2) being at least 64%, at least 0.2% of a dopant selected from V2O5, Nb2O5, Ta2O5, and mixtures thereof, optionally, a stabilizer selected from Y2O3, MgO, CaO, CeO2, and mixtures thereof, at a content of 6% or less, “other oxides” at a content of 6.7% or less.

Abstract: The present invention relates to a melanoma antigen peptide comprising the amino acids sequence selected in the group consisting of SEQ ID NO: 1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4 or SEQ ID NO:5 or a function-conservative variant thereof. Moreover the invention also relates to a melanoma antigen peptide according to the invention for use in the prevention or the treatment of melanoma in patient.

Abstract: A class D amplifier receives and amplifies a differential analog signal which is then differentially integrated. Two pulse width modulators generate pulse signals corresponding to the differentially integrated analog signal and two power units generate output pulse signals. The outputs the power units are coupled to input terminals of integrators via a resistor feedback network. An analog output unit converts the pulse signals to an output analog signal. The differential integration circuitry implements a soft transition between mute/un-mute. In mute, the integrator output is fixed. During the soft transition, the PWM outputs change slowly from a fixed 50% duty cycle to a final value to ensure that no pop noise is present in the output as a result of mode change.

Abstract: The invention discloses a method of separating a biomolecule from at least one other component in a liquid, comprising a step of contacting said liquid with a separation matrix comprising a solid support and polymer chains bound to said solid support. The polymer chains comprise units derived from a first monomer of structure CH2?CH-L-X, where L is a covalent bond or an alkyl ether or hydroxysubstituted alkyl ether chain comprising 2-6 carbon atoms, and X is a sulfonate or phosphonate group.

Abstract: A system for the optical reading of markings printed on an ophthalmic lens (2), includes an image capture device (26), a light source (15) and a support (18, 31) which are configured so that, when the lens is received by the support with a masking element (39) which covers the markings, the source illuminates the lens while rendering the markings visible to the device; and a mobile element on which the source is fixed and which admits a retracted position where it is distanced from the support and a working position where it surrounds at least partially the support and the source looks at the support and these latter are configured so that the source illuminates a rim (34) of the lens so that the light penetrates into its mass (35) and reaches the masking element (33) through the lens.