Abstract: A monument assembly configured to be positioned interior of an aircraft that includes a galley module, a first lavatory module and a second lavatory module. The module is positioned between the first and second lavatory modules, and the first lavatory module and the galley module share a first inboard dividing wall that includes at least a first non-vertical wall section.

Abstract: A radial cylinder hydraulic motor includes oscillating cylinders, in proximity to the outer skirt to the crown or star of cylinder-piston groups; the pistons of the said groups slide on a crankshaft or eccentric shaft, or on interposed organs concentric to it, and create alternate motion in the oscillating cylinders. A respective surface of oscillation for each cylinder of the said groups, in proximity to the outer skirt, is constituted by a portion of cylindrical surface with axial direction parallel to the axis of rotation of the crankshaft or eccentric shaft and positioned in the part of skirt including the diametral plane of lying of the said crown or star of radial cylinders.

Abstract: According to one aspect, the invention relates to an optic fiber amplifier having a high Brillouin threshold, and including: an amplification optic fiber (16) comprising a core and a sheath and suitable for amplifying a signal beam travelling in said core; means for coupling the signal beam in an input end of said amplification optic fiber; means for coupling a pump laser beam for pumping said amplification optic fiber; a structure (330, 340) including a deformable portion around which at least one portion of said amplification optic fiber is wound in the shape of turns, said turns being in contact with a surface of said deformable portion, wherein the friction of said optic fiber on said surface resulting, during the deformation of said deformable portion, in an elongation of said amplification optic fiber according to an elongation profile that varies from one turn to the other.

Abstract: Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of APOA1 or ABCA1. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of APOA1 or ABCA1. Methods for modulating expression of APOA1 or ABCA1 using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of APOA1 or ABCA1.

Abstract: The present invention relates to compounds of formula (I) or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein X1, X2, X3, X4, X5, W1, W2, W3, and W4 are as described. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. In one aspect, the invention relates to selective HDAC3 inhibitors useful for protecting ?-cells and improving insulin resistance. The selective HDAC3 inhibitors are also useful for promoting cognitive function and enhancing learning and memory formation.

Abstract: A third-party application, executing at a mobile device, may be provided with information describing congestion levels in a network, such as a cellular wireless network through which the mobile device connects. In one implementation, the third-party application may select, based on the information describing the congestion levels, a data flow, from a number of data flows, to use when communicating with a destination device, each of the data flows being associated with different quality of service (QoS) parameters and being associated with different charging rates. The mobile device may communicate, through a proxy server, and using the selected data flow, with the destination device. The communication with the destination device may be implemented using sponsored data that is not charged to an account associated with an owner of the mobile device.

Abstract: The invention relates to a method for obtaining a plant in which a homologous recombination event has occurred, preferably resulting in targeting gene insertion in the genome of said plant, by regeneration of the plant from in vitro culture.

Abstract: A server is configured to establish connections for secure element communication sessions. The server receives a request from a device to establish a first secure connection, and establishes the first secure connection with the device in response to the received request. The server sends a request to a Trusted Service Manager (TSM). The sent request instructs the TSM to establish a second secure connection between the TSM and a secure memory. The server receives an authentication request from the TSM to establish the second secure connection, and forwards the authentication request to the device over the first secure connection.

Abstract: The invention is directed to compounds having the formula: wherein: Ar, r, R2-3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

Abstract: A wiper device for cleaning a vehicle window is disclosed. The wiper device has a wiper arm fastened in a torque-proof manner to a wiper shaft via an articulation piece, the wiper arm being arranged pivotably on the articulation piece in a pivot axis, a wiper blade arranged on the wiper arm, and a washing device for the wiper blade, which contains a feed for a washing fluid, wherein the feed runs in the longitudinal axis of the wiper shaft and leads to the wiper blade in a direction running substantially perpendicularly to the longitudinal axis.

Abstract: The present invention relates to a concentrate food composition comprising water, salt and pectin for preparing a bouillon, a soup, a sauce, a gravy or a seasoned dish. The aim of the present invention is to provide a concentrate food composition in the form of a gel at room temperature and which is shape-stable at high-salt levels, while the increase in viscosity upon cooling of the diluted concentrate food composition is very low. It has been found that a concentrate food composition in the form of a stable gel can be obtained when the concentrate comprises water, sodium salt comminuted plant material, pectin and calcium salt, wherein part of said pectin is bound to said comminuted plant material, and part of said pectin is not bound to said comminuted plant material (free pectin) and said free pectin and said bound pectin are present in a ratio of from 0.2 to 200.

Abstract: The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, tautomers, stereoisomers, solvates, hydrates, polymorphs, and compositions thereof. Also provided are methods and kits involving the inventive compounds for treating proliferative diseases (e.g., cancers (e.g., breast cancer, prostate cancer, lung cancer, and ovarian cancer), benign neoplasms, angiogenesis, inflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound of the invention may enhance the anti-tumor immune response by inhibiting or eliminating the immune suppression mediated by immune suppressor myeloid cells (MDSCs), inducing apoptosis, and/or inhibit or down-regulate proteins (e.g., epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER), X-linked inhibitor of apoptosis protein (XIAP), and heat shock protein 90 (Hsp90)) in the subject.

Abstract: A packet gateway in a mobile network generates a unique identifier related to a mobile device owner and inserts the unique identifier into a data request. A merchant website receives and forwards the unique identifier to a customer information mediation server. The customer information mediation server utilizes the unique identifier to retrieve information related to the mobile device owner and provides the retrieved information to the merchant website. The merchant website, in turn, provides portions of the retrieved information to the mobile device as part of the response to the data request. The provided portions of the retrieved information may be included as pre-populated fields, for example in a check-out form of a web page. The mobile device owner may then complete the check-out or other transaction without entering any, or entering only limited, information related to the owner.

Abstract: A method of preparing a beverage in a brewing device is provided, the device comprising an infusion chamber (10) with a bottom rim (12) which defines an opening; a capsule holder (20) for receiving a capsule (30), the capsule holder comprising a sidewall (24) having an upper rim (23), a filter (25) and an openable and closable passage (29) on the opposite side of the filter from the upper rim; the method comprising the steps of: inserting a capsule (30) containing infusible beverage material into the capsule holder (20); connecting the upper rim (23) of the capsule holder (20) to the bottom rim (12) of the infusion chamber (10); introducing liquid into the capsule (30) and releasing the beverage material from the capsule so that the liquid and beverage material mix and flow into the infusion chamber (10) so as to brew the beverage; and then after brewing has taken place, opening the passage (29) to allow the beverage to flow from the infusion chamber (10) through the filter (25) and out through the passage.

Abstract: The invention relates to conjugates in which a sterol is functionalized by an ether bond with a water-soluble polymer to which a guiding ligand is bound. These conjugates improve the physico-chemical and delivery properties of their carrying vesicles, making these more stable, homogeneous and effective. A method for their preparation, a pharmaceutical composition containing said liposomes, and their therapeutic use are described as well.

Abstract: A transmission line transformer (TLT) and a device for delivering serial digital signals at relatively high rates which comprises four such TLTs is provided. Each TLT has a primary and secondary coils winded at the same direction around a common core. Each of the primary and secondary coils comprises two segments of wires. The four segments of wires are grouped to a bundle which is axially twisted, wherein this twisting is characterized by a predefined number of full rotations relative to the axis of the bundle per a unit length, measured along this axis.

Abstract: A new variety of Floribunda rose suitable for garden decoration, having flowers of peachy pink coloration.

Abstract: The invention provides methods and compounds for the treatment of neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, ALS (Amyotrophic Lateral Sclerosis), traumatic brain injury, ischemic brain injury or a stroke. In one aspect the compounds are HDAC1 activators. Exemplary HDAC1 activators include metal chelators, iron chelators, deferoxamin, flavonoids, compounds comprising a catechol moity, ginkgetin K, Chembridge 5104434, sciadopilysin, tetrahydrogamboic acid, TAM-11, LY 235959, CGS 19755, SK&F 97541, etidronic acid, levonordefrin, methyldopa, ampicillin trihydrate, D-aspartic acid, gamma-D-glutamylaminomethylsulfonic acid, phenazopyridine to hydrochloride, oxalamine citrate salt, podophyllotoxin, SK&F 97541, (+?)-4-amino-3-(5-chloro-2-thienyl)-butanoic acid, (RS)-(tetrazol-5-yl) glycine, R(+)-SKF-81297, gambogic acid, and derivatives thereof.

Abstract: A latch has a displaceable latching element in a housing for engagement with a separate striker arm to be latched behind an engagement shoulder of the latching element. The housing mounts a cylinder lock to receive a key from the front. A rotor is mounted on the rear of cylinder lock and rotation of the key rotation the rotor to drive a locking element to engage and lock the latching element. The rotor may also be axial displaceable against spring biasing responsive to a rear unit pushing element whereby unlocking from a rear cylinder lock may rotate the rotor to unlock and pushing causes the latching element to be displaced against its biasing to release the striker arm. Embodiments include a gravity biased and manually opened latch and a spring biased self-locking embodiment.

Abstract: The present invention provides a solution formulation for inhalation comprising: a liquid phase; an active ingredient containing a carboxylic ester in which the oxygen atom is covalently bound to a quaternary nitrogen-containing heterocycle, dissolved in the liquid phase; and a magnesium or calcium salt, dissolved in the liquid phase. The formulation is particularly suited to pMDIs and nebulisers.