Abstract: A cryopreservation device for storing reproductive biological material is provided. The device comprises an elongate first member includes an elongate first member extending between a distal end and a proximal end, a first bulge portion disposed around a circumference of the first member, and a trough defined within the first member, the trough being configured to receive a reproductive biological sample thereon. A second member includes a second member with a lumen defined therethrough. The second member is configured to slide over the first member and the inner diameter of the second member is similar to an outer diameter of the bulge portion to form a seal between the first and second members.

Abstract: This invention relates to pharmaceutical compounds and nutritional supplements that are acetylated derivatives of naturally occurring amino acids and acetylated derivatives of peptides derived from naturally occurring amino acids containing hydroxyl groups. They are as useful as anti-platelet drugs, and as nutritional supplements.

Abstract: The present document describes a CPU platform interface method and device for synchronizing a stream of motion codes with a video stream. The method and device use the video stream time stamps and movie identity information from the software movie player along with the CPU time clock to fill a queue of motion code frames and determine when the frames will be sent as a motion stream to one or more actuators of a motion platform.

Abstract: The present disclosure relates to a device comprising a mono-crystalline substrate, the mono-crystalline substrate having at least one recessed region which exposes predetermined crystallographic planes of the mono-crystalline substrate, the at least one recessed region further having a recess width and comprising a filling material and an embedded nanochannel, wherein the width, the shape, and the depth of the embedded nanochannel is determined by the recess width of the at least one recessed region and by the growth rate of the growth front of the filling material in a direction perpendicular to the exposed predetermined crystallographic planes. The present disclosure is also related to a method for manufacturing a nanochannel device.

Abstract: The present invention relates to aqueous liquid compositions in which surfactant system is specifically selected so that it cleanses well, but is mild and adequately foaming. Further the composition tolerate relatively large amounts of emollient (to help mildness) while, surprisingly, showing better stability.

Abstract: The invention relates to a wound dressing and methods of preparation and use thereof for promoting healing of a wound bed. In particular, the wound dressing is advantageous for application to a debrided wound bed. The wound dressing comprises an open conduit polymeric foam matrix, and a hydrophilic polymer which is disposed in dry form on the inner surfaces of the conduits within the matrix.

Abstract: The inventive technology, in embodiments, may be described as a socket adaptor featuring automatic conformance to a tube (e.g., the inner surfaces of the end of a tube) upon the application of weight to the adaptor (e.g., to a plunger thereof), thereby allowing the secure connection of one tube to another tube in fast, effective manner.

Abstract: An apparatus and method for determining an analyte concentration of a sample, such as a tissue sample. The apparatus may comprise an emitter, close proximity detectors laterally located less than about 2 mm away from the emitter, and far away detectors laterally located greater than about 0.5 cm away from the emitter. A plurality of wavelengths may be sent from the emitter to the sample, reflected off of the sample, and received by the detectors. The reflectance value measured by the close proximity detectors may be used to calculate one or more scattering coefficients. The reflectance value measured by the far away detectors may be compared with a reflectance value calculated using the scattering coefficients in a numerical inversion of a diffusion model to determine the analyte concentration of the sample.

Abstract: It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).

Abstract: An optical component (10) comprises at least one transparent set of cells (15) juxtaposed parallel to a surface of the component, each cell having a size and a geometry that are different from those of its neighbors forming a network of cells with random distribution and random geometry, parallel to the surface of the component. Each cell is hermetically sealed and contains at least one substance with optical property. The invention also comprises a method of producing such an optical component and its use in the fabrication of an optical element. The optical element can in particular be a spectacle lens.

Abstract: Improved topical gel compositions, such as those containing brimonidine, for the treatment of skin disorders are described. The gel compositions contain carbomer and methylparaben, and are substantially free of methylparaben crystalline particles after an extended period of storage.

Abstract: Device for energy absorption in particular for an automotive vehicle seat upon impact, said device comprising a first element substantially in the form of a plate with a hole and a second element inserted in the hole, said first element comprising a series of cutouts that are successive along a deformation direction and define a series of yokes between each other extending along a direction of elongation transversal to the direction of deformation, said yokes having each a length along the direction of elongation, said length increases strictly from one yoke to the next according to the distance of the yokes in relation to the second element and the yokes having an overall concavity turned towards the second element.

Abstract: A method of assessing the performance of a radio transmitting means of, or intended for use in, a user terminal of a mobile telecommunications network, the transmitting means having a plurality of correction factors that are adjustable for improving the performance of the transmitting means and whose values together define a point in a correction space, the method comprising allocating values to the factors to specify a point in the space, measuring the performance of the transmitting means to determine as an error distance the distance of said point from an optimum point in said space that gives best performance of the transmitting means in terms of said factors and using said distance in the identification of said optimum point. Corresponding program code and apparatus is also envisaged.

Abstract: Sealing systems for high pressure applications that provide electrical isolation between joined elements as well as enhanced resistance to leakage of media during a fire. High pressure sealing is accomplished using a metallic core to which an electrically isolating material is bonded on either or both sides. Sealing is achieved through a dielectric sealing element, such as a spring-loaded polytetrafluoroethylene (PTFE) ring. Flanges of the joint may be bolted together with the seal interposed therebetween, and the flanges bolted together. In the event of a fire, heat may be generated that is at a high enough temperature to burn away the isolating material and PTFE ring. Systems of various embodiments provide a metal core backup seal and a compression limiter, which, respectively, prevent the media from leaking from the joint and maintain bolt load at the flanges.

Abstract: A method for handover of User Entity (UE) by a source Base Station (BS) is provided. The method includes determining whether to handover the UE using an X2 interface, transmitting a handover request message to a target BS, the handover request message including Closed Subscriber Group (CSG) information of the target BS, and receiving a handover request acknowledgement message from the target BS, wherein the determining of whether to handover the UE using the X2 interface includes, if there is the X2 interface between the source BS and the target BS, and if the target BS does not support a CSG or the target BS supports a same CSG supported by the source BS, determining to perform the handover of the UE using the X2 interface, and obtaining the CSG information of the target BS through an X2 interface set up procedure.

Abstract: In this disclosure, a method is described wherein the method comprises mixing a therapeutic gas or a therapeutic liquid or a combination thereof and a liquid carrier in a high shear device to produce a dispersion; and administering the produced dispersion intravenously to a patient; wherein the produced dispersion contains nanobubbles of the therapeutic gas or droplets of the therapeutic liquid with a mean diameter of less than about 1.5 ?m. In this disclosure, a system is also described wherein the system comprises a therapeutic gas source or a therapeutic liquid source or a combination thereof, a liquid carrier source; a high shear device (HSD) having an inlet, an outlet, at least one rotor, and at least one stator separated by a shear gap; and a pump configured to control the flow rate and residence time of a fluid passing through the high shear device.

Abstract: Methods and devices are provided for activating brown adipose tissue (BAT). Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss. In one embodiment, a medical device is provided that activates BAT by electrically stimulating nerves that activate the BAT and/or electrically stimulating brown adipocytes directly, thereby increasing thermogenesis in the BAT and inducing weight loss through energy expenditure.

Abstract: Herein disclosed is a method of removing at least one component from a feed by subjecting the feed to high shear in the presence of carbon dioxide to produce a high shear-treated product and separating the at least one component from the high shear-treated product to produce a component-reduced product. Also disclosed is a method of removing asphaltenes from asphaltenic oil by subjecting the asphaltenic oil to a shear rate of at least 10,000 s?1 in the presence of carbon dioxide to produce a high shear-treated product and separating asphaltenes from the high shear-treated product to produce an asphaltene-reduced product oil. Systems are also provided for carrying out the methods.

Abstract: In this disclosure, methods and systems for drug delivery utilizing high shear are disclosed. In an embodiment, a method comprises (1) subjecting a therapeutic fluid containing a drug to high shear; and (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug in nano-size. In an embodiment, a method comprises (1) subjecting a drug carrier and a therapeutic fluid containing a drug to high shear; and (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug carrier loaded with the drug. In an embodiment, a method comprises (1) applying high shear to a drug carrier and a therapeutic fluid containing a drug; (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug-loaded carrier; and (3) modifying the drug-loaded carrier with a targeting moiety to obtain a modified drug-loaded carrier.