Abstract: An analgesic and a delivery agent are combined in a pharmaceutical composition such that, on introduction into the nasal cavity of a patient to be treated, the analgesic may be delivered to the bloodstream to produce within 30 minutes a therapeutic plasma concentration, Cther, of 0.2 ng/ml or greater which is maintained for a duration Tmaint of at least 2 hours. The analgesic may be an opioid analgesic or a non-steroidal anti-inflammatory drug.

Abstract: A method for manufacturing a member for purifying exhaust gas for an automobile exhaust line, including an enclosure, an exhaust gas purification unit arranged in the enclosure, and at least one element for supporting the unit. The method includes the following steps: obtaining a first quantity representative of a mass (Mb) of the exhaust gas purification unit; using at least the first quantity obtained, determining an installation density (dmounted) of the or each support element; determining at least one diameter (Denclosure) of the enclosure as a function of the determined installation density (dmounted) ; assembling the enclosure, the support element(s) and the gas purification unit, so as to obtain the diameter that was determined for the enclosure and the installation density (dmounted) that was determined for the support element(s).

Abstract: A light emitting device generates a broadband light beam in response to an excitation light beam. The light emitting device includes a matrix in which is provided a plurality of fluorescent components of different types. Each type of fluorescent component has an absorption spectrum and an emission spectrum respectively differing from absorption and emission spectra of other types of fluorescent components. The matrix and the types, concentration and positioning of the fluorescent components are selected to output the broadband light beam in response to the excitation light beam. The types of fluorescent components may include fluorescent compounds, quantum dots or a combination thereof. The light-emitting device above may be used as a fluorescent standard, or incorporated into a light source. Scattering elements may also be incorporated in the matrix.

Abstract: Embodiments of the present invention provide steam oven drain valve systems and methods for draining steam ovens and associated water lines on aircraft and other passenger transport vehicles.

Abstract: The invention provides dry powder pharmaceutical formulations comprising an ascorbic acid derivative that demonstrate good inhalation performance and dry powder inhalers containing them.

Abstract: The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N?,N?-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE The invention further relates to methods for preventing, treating or managing TACE-related diseases or disorders in mammals comprising administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of said lipophilic diesters of the chelating agent BAPTA.

Abstract: The present invention provides a polynucleotide which consists of a partial sequence of a polynucleotide encoding the amino acid sequence as shown in SEQ ID NO:2, wherein the former polynucleotide encodes a polypeptide consisting of a partial amino acid sequence of SEQ ID NO:2 whose N-terminus starts between positions 564 and 621 of SEQ ID NO:2.

Abstract: A cosmetic composition is provided which includes from 1 to 5% of a water-insoluble UVA organic sunscreen agent having a ?max between 330 and 380 nm and a photo protective enhancing agent including a monomeric organic amide, imide or nitrile of molecular weight no higher than 500 and having a dielectric constant ranging from 6 to 20, and a carrier which includes a crystalline gel structurant system.

Abstract: A compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group or the like which may be substituted with a C1-6 alkyl group, Ar2 represents a phenyl group or the like which may be substituted with a C1-6 alkoxy group, X1 represents a double bond or the like and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, is effective as a therapeutic or prophylactic agent for a disease caused by A?.

Abstract: A method includes the following steps: a first shell (12) is immobilized in a first shell carrier (6); a second shell (29) is immobilized in a second shell carrier (27); the first shell carrier (6) is oriented in such a way that a useful moulding surface of the first shell (12) faces upwards and forms the base of a vessel; a pre-determined quantity of polymerizable material is placed in the vessel; the first shell carrier (6) and the second shell carrier (27) are moved into a pre-determined relative position wherein the first shell (12) and the second shell (29) are in a pre-determined moulding position, by at least partially arranging the second shell (29) in the vessel, at a distance from the edges thereof. The inventive device includes a structure for positioning the shell carriers.

Abstract: A system for generating two-dimensional views of a three-dimensional model is provided. The system includes an active building model system generating one or more user-selected two-dimensional views of a three-dimensional building model. A floor plan view location system receives user control data and places a two-dimensional floor plan view in a user-selected location of a viewing window. An elevation view location system receives user control data and places a two-dimensional elevation view in a user-selected location of the viewing window.

Abstract: An electrolytic capacitor (1) includes a first electrode (2) and a second electrode (3) each including carbon and an aqueous electrolyte (4) situated at the interface of the two electrodes. The carbon surface of the first electrode (2) has an atomic degree of functionalization which is at least twice that of the carbon surface of the second electrode (3).

Abstract: Methods for improving the accuracy of characterizing unmonitored paths or virtual meters in a utility system. The hierarchical arrangement of IEDs in the utility system is determined. Measured quantities of a characteristic of the utility being monitored are received and error-adjusted using statistical or absolute methods. The statistical method accounts for the mean and standard deviation associated with error measurements of the subject IED, and the absolute method uses the absolute value of the error measurement, expressed as a percentage, to produce ranges of measured quantities within an error tolerance. The differences between the error-adjusted quantities are analyzed to determine whether an unmonitored path exists, and if so, whether the virtual meter is consuming or supplying the utility. The order in which IEDs are read is determined so that a parent and its children are read in sequence to increase synchronicity of the received data and the virtual meter evaluation.

Abstract: It is an object of the present invention to establish a method of establishing a cell with a remarkably high hERG channel expression level for use in predicting adverse effects based on hERG channel inhibition in research and development of drugs, and to thereby establish a highly sensitive and high throughput evaluation method. By inserting a hERG gene into a retrovirus vector plasmid or lentivirus vector plasmid to thereby prepare a virus vector, concentrating the vector by ultracentrifugation if necessary, transferring the hERG gene into cells and expressing hERG channels therein, it has become possible to secure an expression level effective in measurements using a fully automated high throughput patch clamp system or dyes.

Abstract: The present document describes an actuated chair for inducing motion with respect to the ground as a function of motion signals synchronized with a video output of a feature length movie. The chair comprises a seat base, and an actuating base for receiving the motion signals. The actuating base comprises three link members, namely a first link member, a second link member and a third link member. Each link member has one translational degree of freedom and two rotational degrees of freedom. The first link member and the second link member are attached to the seat base closer to the rear edge than the third link member. The actuating base further comprises three linear actuators for inducing motion to the seat base. The actuators are fixed to the frame and each actuator is respectively connected to the seat base using a respective one of the three link members.

Abstract: A system and method for controlling the flow of fluid for an inflatable body support 30 system, such as a mattress, having multiple, inflatable chambers. Each inflatable chamber can be selectively and independently inflated and deflated to vary the pressure exerted from the mattress surface to selected areas of a human body, thereby preventing the formation of decubitus ulcers. The system includes a valve assembly that includes a plurality of solenoid valves to direct air at a pressure of less than 1 pound per square inch into each chamber and a separate vent valve all operable by a controller to regulate the level of inflation of each inflatable chamber.

Abstract: A flexible amperage flag that indicates an amperage rating of a trip unit in a circuit breaker. The flag is molded with a housing of the trip unit so that it remains with the trip unit even when installed into a different circuit breaker. The flag includes an attachment member secured to a wall of the trip unit and a flexible leg integral with the attachment member. A top surface member indicates the amperage rating and protrudes through an auxiliary cover of the circuit breaker so as to be visible through the panelboard into which the circuit breaker is installed and is connected to the top surface member. During a circuit interruption, the pressure created by the exploding gas forces the auxiliary cover away from the trip unit, creating stress on the flag. The flexible leg permits the flag to move with the auxiliary cover and return to its original form without breaking.

Abstract: Novel inverse latices based on fatty alcohol ethers of formula R1—O—R2 (I) in which R1 and R2 represent, independently from one another, a linear or branched alkyl radical comprising from 5 to 18 carbon atoms; and cosmetic, dermocosmetic, dermopharmaceutical or pharmaceutical compositions comprising them.

Abstract: A method is presented for forming mono-crystalline germanium or silicon germanium in a trench. In an embodiment, the method comprises providing a substrate comprising at least one active region that is adjacent to two insulating regions, forming in the active region a trench having a width of less than 100 nm, and forming in the trench a fill layer at a temperature of less than 450° C. that comprises germanium or silicon germanium and substantially fills the trench. The method further comprises heating the fill layer to a temperature sufficient to substantially melt the fill layer and allowing re-crystallization of the substantially melted fill layer, thereby forming mono-crystalline germanium or silicon germanium in the trench. In an embodiment, the method further comprises forming a mono-crystalline germanium or silicon germanium fin by removing at least a portion of the insulating regions. The mono-crystalline fin may be comprised in a fin field-effect-transistor (finFET).

Abstract: Multiple substrates that carry quantum devices are coupled to provide quantum mechanical communicators therebetween, for example, using superconducting interconnects, vias, solder and/or magnetic flux. Such may advantageously reduce a footprint of a device such as a quantum processor.