Abstract: A mechanism for adjusting the position of a knife on a rotary cutterhead mounted for rotation about a central axis comprises at least three dynamics positioning points for allowing a user to adjust the knife axially, radially and tangentially with respect to the central axis of the cutterhead.
Abstract: A process for the manufacture of a refractory block including more than 80% zirconia, in percentage by weight based on the oxides. The process includes the following successive stages: melting, under reducing conditions, of a charge including more than 50% zircon, in percentage by weight, such as to reduce the zircon and obtain a molten material, application of oxidizing conditions to the molten material, casting of the molten material, and cooling until at least partial solidification of the molten material in the form of a block. Also, the process can include heat treatment of the block.
Type:
Grant
Filed:
October 9, 2018
Date of Patent:
April 25, 2023
Assignee:
SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN
Abstract: A suspension mat for a vehicle seat comprises a spring element, and a guiding support for at least one electrical cable. The guiding support is molded onto the spring element.
Abstract: The invention provides compounds of formula (I): where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds and methods of using such compounds to treat respiratory diseases.
Type:
Grant
Filed:
February 4, 2021
Date of Patent:
April 25, 2023
Assignee:
THERAVANCE BIOPHARMA R&D IP, LLC
Inventors:
Daniel D. Long, Cameron Smith, Corbin Thompson
Abstract: Antiballistic armour plate includes a ceramic body including a hard material, provided, on its inner face, with a back energy-dissipating coating. The ceramic body is monolithic. The constituent material of the ceramic body includes grains of ceramic material having a Vickers hardness that is higher than 15 GPa, and a matrix binding the grains, the matrix including a silicon nitride phase and/or a silicon oxynitride phase, the matrix representing between 5 and 40% by weight of the constituent material of the ceramic body. The maximum equivalent diameter of the grains of ceramic material is smaller than or equal to 800 micrometres. The constituent material of the ceramic body has an open porosity that is higher than 5% and lower than 14%. The metallic silicon content in the material, expressed per mm of thickness of the body, is lower than 0.5% by weight.
Type:
Grant
Filed:
July 7, 2017
Date of Patent:
April 25, 2023
Assignee:
SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN
Abstract: Systems, and method and computer readable media that store instructions for slowing or stopping a progress, towards a target, of a drone controlled by a remote control unit.
Abstract: A cutting tool includes a base having a table surface. The table surface has a circular turntable and a cutting platform connected with respect to the circular turntable. The cutting platform is rotatable about an axis of the circular turntable. At least one connector releasably locks the cutting platform to the turntable at a number of positions about the axis. A blade housing and blade are suspended above the cutting platform. A handle is attached to the cutting tool to raise and lower the blade. The handle is rotatably supported by a cam integrated with the blade housing.
Abstract: A cleansing composition comprising a sulfate surfactant; a fatty acid soap; a silver compound; a thickening agent; and a nitrate. A pH of the cleansing composition is 5 to 10. Another cleansing composition comprising a sulfate surfactant; a silver compound; a thickening agent; a nitrate; and a preservative. A pH of this cleansing composition is 4 to 5.5.
Type:
Application
Filed:
April 29, 2021
Publication date:
April 20, 2023
Applicant:
CONOPCO, INC., D/B/A UNILEVER
Inventors:
Joseph Oreste CARNALI, Prem CHANDAR, Connor Patrick WALSH
Abstract: A cutting tool includes a base with a table surface and a cutting platform. The cutting platform is suspended above the table surface and includes a blade housing. The blade housing includes a blade holder with a linear blade. The blade holder is slidably connected through the base housing. A housing column is configured on the base of the cutting tool. A handle raises and lowers the blade. A guide rail is pivotally connected to the table surface by at least one releasable guide rail connector. The guide rail is releasably locked with respect to the blade at a plurality of angles.
Abstract: A cutting tool includes a base with a table surface and a cutting platform. The cutting platform is suspended above the table surface and includes a blade housing. The blade housing includes a blade holder with a linear blade. The blade holder is slidably connected through the base housing. A housing is configured on the base of the cutting tool. The housing includes a housing platform and a housing cover, which are supported by two housing side pieces. A handle raises and lowers the blade. A guide rail is pivotally connected to the table surface by at least one releasable guide rail connector. The guide rail is releasably locked with respect to the blade at a plurality of angles.
Abstract: A rifle has a fixed main body, including a barrel, a receiver with an upper opening, and a breech element. A trigger group is at least partially housed in the receiver, including a trigger, a hammer device operable by the trigger, and a safety member positionable in a shooting position, disengaged from the hammer device and in a safety position, engaged with and blocking the hammer device. A carriage assembly with a shutter group is positioned on the receiver at the upper opening and axially movable by the user between an advanced shooting configuration and a retracted rearming configuration. The carriage assembly includes a safety group controllable by the user, with the carriage assembly in the advanced configuration, in a ready-to-shoot configuration, in which it is disengaged from the safety member, and a safety configuration, in which it engages and keeps the safety member in the safety position.
Abstract: The present invention is in the field of personal care compositions, in particular compositions comprising antiperspirant actives. The present invention more particularly relates to compositions which do not contain the conventional and well established metal based actives, yet exhibit similar efficacy. This is achieved through use of a combination of a film forming polymer, a specific solvent and a particulate filler.
Abstract: A rifle has a fixed main body, including a barrel, a receiver with an upper opening, a breech element, and a trigger assembly at least partly accommodated in the receiver. The rifle has a slide assembly including a shutter group positioned on the receiver at the upper opening and axially movable by the user between an advanced shooting configuration and a retracted rearming configuration, and vice versa. The rifle includes a recoil group at least partially accommodated in the receiver, for cooperating with the slide assembly having a thrust device with a thrust lever, which is rotationally movable and a thrust spring, which performs torsional action on the thrust lever. The thrust lever extends between a lever upper end and a lever lower end. The lever upper end is suitable engageable with the advancing slide assembly to push it into the advanced configuration.
Abstract: A firearm, such as a rifle, has a trigger group operable by the user in order to control the shooting action. The trigger group includes a trigger and an adjustment device for adjusting the intensity needed to operate the trigger. The adjustment device includes a rod (151) movable by the trigger extending between a trigger end and a free end. A command member engaged with the rod is positionable in a predefined operating axial position. The rod slidably engages with the command member. A thrust spring acts on the rod between the engagement end and the command member. Elastic action of the thrust spring on the trigger is a function of the axial operating position of the command member.
Abstract: Provided herein are methods of treating cancer (e.g., melanoma or RCC), which comprise administering to a human patient in need thereof: (a) a PD-1 antagonist; (b) a CTLA4 antagonist; and (c) lenvatinib represented by Formula (I), or a pharmaceutically acceptable salt thereof. Also provided are kits containing such agents and uses of therapeutic combinations of such agents for the treatment of cancer.
Abstract: A mobile device has a display, a memory, an antenna, a transceiver connected to the antenna for communicating voice and data through a wireless communication system, at least one processor, and executable instructions stored in the memory.
Abstract: A system for producing a hydrocarbon by high-temperature Fischer-Tropsch synthesis is described. The system includes a Fischer-Tropsch synthesis unit, a reaction water separation unit, and a catalyst reduction unit. The catalyst reduction unit uses a gas containing the tail gas of the synthesis unit as a reducing gas and a small amount of synthesis gas for adjusting the hydrogen to carbon ratio, to react with the Fischer-Tropsch synthesis catalyst. After the reduction reaction, the reacted gas is cooled to room temperature, and enters a gas-liquid separator to obtain a gas phase and a liquid phase. The gas phase flows to a cryogenic separation unit to recover gaseous hydrocarbons. The liquid phase is separated into reaction water and Fischer-Tropsch oil products. The reduced catalyst is sent to the Fischer-Tropsch synthesis unit.
Abstract: An anode, in particular an anode for the use in aluminium electrolysis cells, includes an anode body with a first stub hole for the insertion of a stub for the connection with a voltage source. The anode includes at least a first aluminium core and a second aluminium core that are arranged inside the anode body for the connection with the voltage source. A first distance between the first aluminium core and the bottom of the anode is different from a second distance between the second aluminium core and the bottom of the anode.
Abstract: The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the invention. The present invention further relates to, but is not limited to, methods for treating disorders associated with SHP2 deregulation with the compounds ad compositions of the invention.
Type:
Grant
Filed:
October 24, 2017
Date of Patent:
April 18, 2023
Assignees:
D. E. Shaw Research, LLC, Relay Therapeutics, Inc.
Inventors:
Fabrizio Giordanetto, Jack Benjamin Greisman, Paul Maragakis, Alexander M. Taylor, Lucian V. Dipietro, Elizabeth H. Kelley, André Lescarbeau, Mark Andrew Murcko, Levi Charles Thomas Pierce, Kelley C. Shortsleeves, W. Patrick Walters, Sathesh Bhat, Eric Therrien, Markus Kristofer Dahlgren
Abstract: A device includes a circular buffer, which, in operation, is organized into a plurality of subsets of buffers, and control circuitry coupled to the circular buffer. The control circuitry, in operation, receives a memory load command to load a set of data into the circular buffer. The memory load command has an offset parameter indicating a data offset and a subset parameter indicating a subset of the plurality of subsets into which the circular buffer is organized. The control circuitry responds to the command by identifying a set of buffer addresses of the circular buffer based on a value of the offset parameter and a value of the subset parameter, and loading the set of data into the circular buffer using the identified set of buffer addresses.