Abstract: The present invention relates to an antimicrobial composition, more particularly to a method and a composition to prevent or treat malodour, especially body malodor. This is achieved through a composition that comprises alkyl substituted dihydroxy benzene in combination with thymol or terpineol. The composition is also seen to have anti-acne benefits.
Abstract: An apparatus for monitoring a user's health and/or sleep and/or the efficacy of a treatment (e.g. a sleep treatment or other type of health treatment) can include use of a wearable electronic device. The device can include an array of sensors for collecting user data. The user data can be used by the device to evaluate criteria related to the user's health to monitor efficacy of a treatment. In addition, or alternatively, the collected data can be transmitted to a central server and/or input/output device for evaluating different criteria for monitoring the user's health and/or sleep as well as the efficacy of a treatment being provided to the user.
Type:
Application
Filed:
March 25, 2021
Publication date:
May 18, 2023
Applicant:
Eisai R&D Management Co., Ltd.
Inventors:
Rajeev NARAYANAN, Tushar D. PATEL, Alexander SCOTT, Mitsuo KOSAKA, David LEVIN
Abstract: The invention is directed to a stable, high polyol containing wash composition. More particularly, the invention is directed to a wash composition comprising polyol, surfactant and a gelling agent whereby the wash composition is air pocket free, has excellent moisturizing capabilities, a viscosity of 40,000 cps or less, and a slope from ?0.5 to 0.0. The isotropic composition has an oil-like appearance.
Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
Abstract: The invention relates to a varnished banknote comprising from 0.0015 to 2.5 wt. % of a lactam; and to the use of a lactam to either impart anti-biofilm properties to a banknote or to inhibit biofilm growth on a banknote substrate.
Abstract: Provided herein are vaccines including coronavirus antigens and E6020, as well as methods of mitigation of coronavirus infection by administering those vaccines.
Type:
Application
Filed:
April 6, 2021
Publication date:
May 18, 2023
Applicants:
Eisai R&D Management Co., Ltd., Variation Biotechnologies Inc.
Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
Abstract: The invention relates to a cosmetic active ingredient comprising at least one extract of Avena strigosa and at least one extract of Ononis spinosa. The invention also relates to a composition including it, a method for obtaining it and the use of this cosmetic active ingredient, in particular for its anti-graying effect on the hair.
Abstract: The mechanical timepiece regulator of the invention comprises a flexure bearing oscillator and a double detent escapement, the oscillator comprising a balance wheel (1) connected to an elastic suspension (2a, 2b) arranged to guide and apply a restoring force to the balance wheel (1) in a plane of oscillation. The escapement comprises an escape wheel (3) and an anchor (4) integrated into the balance wheel (1) and having two arms (5, 6) arranged to receive alternately the impulses of the escape wheel (3). The escapement furthermore comprises two detents (7, 8) alternately locking the escape wheel (3) between two impulses and interacting with the arms (5, 6) of the anchor to release the escape wheel (3) before each impulse, without direct interaction between the anchor and the escape wheel.
Type:
Grant
Filed:
January 24, 2020
Date of Patent:
May 16, 2023
Assignee:
CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT
Inventors:
Gregory Musy, Olivier Laesser, François Barrot
Abstract: The present invention relates to the identification of proteins of the WNT signaling pathway as therapeutic targets of pigmentation disorder and as biomarkers of pigmentation status. The invention in particular relates to products and methods for treating a hypopigmentation disorder. The invention also relates to products and methods for detecting, diagnosing, staging or monitoring the course of hypopigmentation disorder and is particularly suited for human subjects.
Type:
Grant
Filed:
December 9, 2020
Date of Patent:
May 16, 2023
Assignees:
INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Côte d'Azur, CHU de Nice
Abstract: A method, device, and system is described herein for pushing a rotary drill bit. Pushing the rotary drill bit can include receiving a target direction in a formation to push the rotary drill bit while drilling a wellbore in a formation. Pushing the rotary drill bit can also include opening, at a first rotational position of a rotary bit pushing device disposed proximate to the rotary drill bit within the wellbore, a first inlet port of a first flow regulator. Pushing the rotary drill bit can further include closing, after the first rotational position of the rotary bit pushing device, the first inlet port. Pushing the rotary drill bit can also include sending, to a second flow regulator of the rotary bit pushing device, a second quantity of drilling fluid.
Abstract: A ripple diaphragm circulator includes a body inside which there is an internal chamber comprising an inlet opening and an outlet opening for fluid; and a flexible diaphragm placed in the chamber so as to be able to ripple there. The circulator further includes an actuating mechanism including at least one motor and a mechanical linking part linking the motor to the first edge of the diaphragm so as to move it in a reciprocating motion. The circulator also includes a device for detecting at least one value representative of a movement of the diaphragm, a power supply unit delivering an electrical power supply signal to the motor according to a detection signal.
Type:
Grant
Filed:
December 5, 2018
Date of Patent:
May 16, 2023
Assignee:
AMS R&D SAS
Inventors:
Guy Delaisse, Jean-Baptiste Drevet, Harold Guillemin
Abstract: The present invention relates to the field of inflammation-associated disorders or conditions, more particularly to gut inflammation. Provided herein are means and methods to diagnose and treat or reduce the severity of inflammation-associated disorders or conditions in a subject in need thereof.
Inventors:
Jeroen Raes, Gwen Falony, Mireia Valles-Colomer, Lindsay Devolder, Severine Vermeire, Sara Vieira-Silva, João Guedelha Sabino, Marie D'Hooghe, Jacques De Keyser
Abstract: The invention relates to a gear motor (1) for a motor vehicle wiper system including an electric motor (2) including a rotor (20) and a rotation shaft (22) fixed to the rotor, a reduction gear mechanism (3) including a worm/worm wheel system, a device for generating an axial load configured to offset axial play of the rotation shaft (22), including a retaining wedge (6) mounted in a sliding manner in a radial direction of said rotation shaft (22), said retaining wedge (6) exerting an axial load on the outer race of a ball bearing (5) configured to guide the rotation shaft. According to the invention, said retaining wedge (6) is arranged in an intermediate position between the seat (40) of the bearing support (4) and the worm (30) directly adjacent to the worm wheel (31), said axial load (Fa) exerted by the retaining wedge (6) on the outer race (51) of the ball bearing (5) being in the direction away from the worm (30).
Abstract: The invention provides two crystalline freebase forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester. The invention also provides pharmaceutical compositions comprising the crystalline freebase or prepared using the crystalline freebases; processes and intermediates for preparing the crystalline freebases; and methods of using the crystalline freebases to treat a pulmonary disorder.
Abstract: The present invention relates to a composition comprising a plurality of particles, wherein said particles comprise: 30 to 95 wt. % polyethylene glycol, wherein the polyethylene glycol has a weight average molecular weight from 4000 to 12000; 0.1 to 60 wt. % secondary carrier, wherein the secondary carrier is provided in the form of particles, the particles having a volume average particle size of 35 to 75 ?m; and 0.1 to 30 wt. % perfume materials. The present invention also relates to a method of producing the particles and use of particles the particles.
Type:
Application
Filed:
February 25, 2021
Publication date:
May 11, 2023
Applicant:
Conopco, Inc., d/b/a UNILEVER
Inventors:
Stephen Thomas KENINGLEY, Andrew Peter ROSE
Abstract: A method for attaching a plastic barrel configured to guide an output shaft of a mechanical device to a housing for the mechanical device is disclosed. The housing includes a chimney delimited by an upper edge and a base, the chimney being arranged to partially surround the output shaft, the plastic barrel having a lateral protuberance. The method involves at least the following steps: inserting a first end of the plastic barrel into the chimney of the housing until the lateral protuberance axially abuts against the upper edge of the chimney, and at least partially deforming the first end of the plastic barrel in order to form an axial counter-abutment.