Patents Assigned to Danmarks Tekniske Universitet
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Publication number: 20180305709Abstract: A method for producing individual or libraries of tri- to pentadecaketide-derived aromatic compounds of interest by heterologous expression of polyketide synthase and aromatase/cyclase in a recombinant host cell.Type: ApplicationFiled: June 10, 2016Publication date: October 25, 2018Applicants: DANMARKS TEKNISKE UNIVERSITET, KØBENHAVNS UNIVERSITET, KØBENHAVNS UNIVERSITETInventors: Rasmus John Normand FRANDSEN, Uffe Hasbro MORTENSEN, Hilde Cornelijne COUMOU, Rubini Maya KANNANGARA, Bjørn MADSEN, Majse NAFISI, Johan ANDERSEN-RANBERG, Kenneth Thermann KONGSTAD, Finn Thyge OKKELS, Paiman KHORSAND-JAMAL, Dan STÆRK, Birger Lindberg MØLLER
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Patent number: 10100290Abstract: An isolated glycosyltransferase (GT) polypeptide capable of: (I): conjugating glucose to flavokermesic acid (FK); and/or (II): conjugating glucose to kermesic acid (KA) and use of this GT to e.g. make Carminic acid.Type: GrantFiled: December 18, 2014Date of Patent: October 16, 2018Assignees: Københavns Universitet, Danmarks Tekniske UniversitetInventors: Rubini Maya Kannangara, Mads Bennedsen, Bjørn Madsen, Kim Binderup, Ulf Thrane, Rasmus John Normand Frandsen, Uffe Hasbro Mortensen, Birger Lindberg Møller, Finn Thyge Okkels
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Patent number: 10088428Abstract: A surface refractive index acquisition system for characterization of a sample is provided. The system comprises a grating device configured to receive the sample, and first and second grating regions. First and second grating periods are selected to provide optical resonances for light respectively in first and second wavelength bands. A light source is configured to illuminate part of the first and second grating regions simultaneously. An imaging system is configured to image light from the grating device and comprises an optical element focusing light in a transverse direction and being invariant in an orthogonal transverse direction, the optical element being oriented such that the longitudinal direction of the grating device is oriented to coincide with the invariant direction of the optical element, and an imaging spectrometer comprising an entrance slit having a longitudinal direction oriented to coincide with the invariant direction of the optical element.Type: GrantFiled: May 8, 2015Date of Patent: October 2, 2018Assignee: Danmarks Tekniske UniversitetInventors: Anders Kristensen, Christoph Vannahme, Martin Dufva
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Patent number: 10081801Abstract: The invention provides a mutant enzyme having trans-sialidase activity (EC 3.2.1.18), characterized by an enhanced trans-sialidase:sialidase ratio when compared to its parent sialidase enzyme. Further the enzyme may be used in a method for trans-sialylating mono- and oligo-saccharides, including galacto-oligosaccharides (GOS), fructo-oligosaccharides (FOS), malto-oligosaccharides (MOS), isomalto-oligosaccarides (IMO), lactulose, melibiose, maltose, glycosyl sucrose, lactosucrose and fucose. Trans-sialidated mono- and oligo-saccharides, produced with the mutant enzyme, are useful in preparing infant formula, a prebiotic nutritional supplement, and a food supplement.Type: GrantFiled: April 11, 2014Date of Patent: September 25, 2018Assignee: DANMARKS TEKNISKE UNIVERSITETInventors: Jørn Dalgaard Mikkelsen, Carsten Jers, Malwina Michalak, Kasper Planeta Kepp, Dorte Møller Larsen
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Patent number: 10064960Abstract: The present invention relates to novel formulations comprising a plurality of nano-sized solid particles and a gel-forming system, useful, e.g. for imaging of the body of a mammal. Also described are kits comprising such formulations and imaging methods utilizing such formulations or kits.Type: GrantFiled: November 26, 2012Date of Patent: September 4, 2018Assignee: DANMARKS TEKNISKE UNIVERSITETInventors: Rasmus Irming Jolck, Morten Albrechtsen, Lise Norkjaer Bjerg, Thomas Lars Andresen
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Patent number: 10053717Abstract: The invention described materials and methods for producing oxidized 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R-MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.Type: GrantFiled: January 30, 2015Date of Patent: August 21, 2018Assignees: University of Copenhagen, Danmarks Tekniske Universitet, Evolva SAInventors: Björn Hamberger, Birger Lindberg Møller, Eirini Pateraki, Johan Andersen-Ranberg, Niels Bjerg Jensen
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Patent number: 10024892Abstract: The present invention relates to a method for assessment of a power system and an early warning system for a power system, the method being based on aperiodic small signal instabilities. The power system has a plurality of generators comprising one or more synchronous machines and is represented by a plurality of nodes of power injection, injecting power into a network having a plurality of nodes and branches. The method for assessment of the power system comprises determining a present state of the power system, calculating system Thevenin impedances from each node of power injection in the power system on the basis of the determined present state of the power system, calculating injection impedances from each node of power injection in the power system on the basis of the determined present state of the power system, determining a stability boundary for each generator based on the calculated system Thevenin impedances and the calculated injection impedances.Type: GrantFiled: May 30, 2012Date of Patent: July 17, 2018Assignee: DANMARKS TEKNISKE UNIVERSITETInventor: Hjörtur Jóhannsson
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Patent number: 10027237Abstract: Resonant power converters and inverters include a self-oscillating feedback loop coupled from a switch output to a control input of a switching network comprising one or more semiconductor switches. The self-oscillating feedback loop sets a switching frequency of the power converter and comprises a first intrinsic switch capacitance coupled between a switch output and a control input of the switching network and a first inductor. The first inductor is coupled in-between a first bias voltage source and the control input of the switching network and has a substantially fixed inductance. The first bias voltage source is configured to generate an adjustable bias voltage applied to the first inductor. The output voltage of the power converter is controlled in a flexible and rapid manner by controlling the adjustable bias voltage.Type: GrantFiled: June 16, 2017Date of Patent: July 17, 2018Assignee: Danmarks Tekniske UniversitetInventors: Mickey P. Madsen, Jeppe Amsdorf Pedersen
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Patent number: 10022703Abstract: The disclosure concerns an improved method of preparation of nanoparticular vanadium oxide/anatase titania catalysts having a narrow particle size distribution. In particular, the disclosure concerns preparation of nanoparticular vanadium oxide/anatase titania catalyst precursors comprising combustible crystallization seeds upon which the catalyst metal oxide is coprecipitated with the carrier metal oxide, which crystallization seeds are removed by combustion in a final calcining step.Type: GrantFiled: April 11, 2014Date of Patent: July 17, 2018Assignee: DANMARKS TEKNISKE UNIVERSITETInventors: Steffen Buus Kristensen, Andreas Jonas Kunov-Kruse, Anders Riisager, Rasmus Fehrmann
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Patent number: 10020747Abstract: The present invention relates to a resonant DC-DC power converter assembly comprising a first resonant DC-DC power converter and a second resonant DC-DC power converter having identical circuit topologies. A first inductor of the first resonant DC-DC power converter and a second inductor of the second resonant DC-DC power converter are configured for magnetically coupling the first and second resonant DC-DC power converters to each other to forcing substantially 180 degrees phase shift, or forcing substantially 0 degree phase shift, between corresponding resonant voltage waveforms of the first and second resonant DC-DC power converters. The first and second inductors are corresponding components of the first and second resonant DC-DC power converters.Type: GrantFiled: April 14, 2015Date of Patent: July 10, 2018Assignee: DANMARKS TEKNISKE UNIVERSITETInventor: Mickey P. Madsen
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Patent number: 10014952Abstract: The present disclosure relates to a method for decoding a combined AM/FM encoded signal, comprising the steps of: combining said encoded optical signal with light from a local oscillator configured with a local oscillator frequency; converting the combined local oscillator and encoded optical signal into one or more electrical signals by means of at least one opto-electrical converter having a predefined frequency bandwidth, thereby providing an amplified and encoded electrical signal having one or more encoded signal current(s), where one type of states have a higher oscillation frequency than other type of states; rectifying the encoded signal current(s), thereby obtaining an encoded power spectrum, wherein said power spectrum has different states, such as “0”-states and “1”-states, with different power levels such that they can be discriminated, said local oscillator frequency is defined by a positive local oscillator frequency-offset from the frequency of one of the states in said encoded optical signal,Type: GrantFiled: February 6, 2015Date of Patent: July 3, 2018Assignee: DANMARKS TEKNISKE UNIVERSITETInventors: Jesper Bevensee Jensen, Bo Pedersen, Roberto Rodes Lopez
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Patent number: 10005067Abstract: The invention contributes to a cost effective way to solve the problem of trace ammonia removal from a hydrogen and nitrogen containing gas. The set of catalysts of the invention selectively oxidized ammonia in ppm concentration even in gas mixtures containing hydrogen gas in concentrations of three orders of magnitude higher than the concentration of ammonia.Type: GrantFiled: May 26, 2015Date of Patent: June 26, 2018Assignee: Danmarks Tekniske UniversitetInventors: Debasish Chakraborty, Ib Chorkendorff, Jakob Lind Olsen, Hugo José Lopes Silva, Morten Godtfred Nielsen
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Publication number: 20180159430Abstract: The three-port direct current converter comprising: at least one input direct current source; at least one storage battery; a primary side circuit; a secondary side circuit; a first single magnetic component shared by the primary side circuit and the secondary side circuit, wherein the primary side circuit comprises a connection between the at least one input direct current source and the at least one storage battery, the primary side circuit configured for operating as a buck converter; a second magnetic component serially coupled to the first single magnetic component, wherein the first and second magnetic components are configured to perform a voltage step-up, wherein the secondary side circuit comprises a connection between the at least one storage battery and at least one load, the secondary side configured for operating as a tapped boost converter; wherein the three-port direct current converter is configured to operate in two mutually exclusive power flow configurations.Type: ApplicationFiled: April 25, 2016Publication date: June 7, 2018Applicant: DANMARKS TEKNISKE UNIVERSITETInventor: Maria Del Carmen Mira Albert
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Patent number: 9991805Abstract: The present invention relates to a resonant DC-DC power converter comprising an input side circuit comprising a positive and a negative input terminal for receipt of an input voltage or current and an output side circuit comprising positive and negative output terminals for supply of a converter output voltage and connection to a converter load. The resonant DC-DC power converter further comprises a rectification circuit connected between an output of a resonant network and the output side circuit. The resonant network is configured for alternatingly being charged from the input voltage or current and discharged through the rectification circuit by a first controllable switch arrangement in accordance with a first switch control signal.Type: GrantFiled: February 26, 2015Date of Patent: June 5, 2018Assignee: Danmarks Tekniske UniversitetInventors: Mickey P. Madsen, Milovan Kovacevic
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Patent number: 9983125Abstract: The present invention relates to a system for detecting terahertz radiation, a camera device, and a method for detecting terahertz radiation.Type: GrantFiled: August 29, 2014Date of Patent: May 29, 2018Assignee: Danmarks Tekniske UniversitetInventors: Krzysztof Iwaszczuk, Peter Uhd Jepsen
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Patent number: 9921315Abstract: Disclosed is a semiconductor radiation detector for detecting X-ray and/or gamma-ray radiation. The detector comprises a converter element for converting incident X-ray and gamma-ray photons into electron-hole pairs, at least one cathode, a plurality of detector electrodes arranged with a pitch (P) along a first axis, a plurality of drift electrodes, a readout circuitry being configured to read out signals from the plurality of detector electrodes; and a processing unit connected to the readout circuitry and being configured to detect an event in the converter element. The readout circuitry is further configured to read out signals from the plurality of drift electrodes, and the processing unit is further configured to estimate a location of the event along the first axis by processing signals obtained from both the detector electrodes and the drift electrodes, the location of the event along said first axis is estimated with a precision being greater than the pitch (P).Type: GrantFiled: November 26, 2014Date of Patent: March 20, 2018Assignee: Danmarks Tekniske UniversitetInventors: Irfan Kuvvetli, Carl Budtz-Jørgensen
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Patent number: 9878309Abstract: The present invention relates to a bimetallic catalyst for ammonia oxidation, a method for producing a bimetallic catalyst for ammonia oxidation and a method for tuning the catalytic activity of a transition metal. By depositing an overlayer of less catalytic active metal onto a more catalytic active metal, the total catalytic activity is enhanced.Type: GrantFiled: October 30, 2014Date of Patent: January 30, 2018Assignee: Danmarks Tekniske UniversitetInventors: Christian Nagstrup Conradsen, Sine Ellemann Olesen, Debasish Chakraborty, Ib Chorkendorff
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Patent number: 9869652Abstract: Disclosed herein is a biosensor for detection of a target substance in a sample with impedance spectroscopy, the biosensor comprising 1) a first non-conducting substrate comprising a primary substrate surface; 2) a conducting polymer electrode layer comprising one or more conducting polymers layers, the conducting polymer electrode layer comprising a primary electrode surface and a secondary electrode surface, wherein the secondary electrode surface covers part of the primary substrate surface; 3) a probe layer bonded to part of the primary electrode surface; and 4) a second non-conducting substrate comprising a secondary substrate surface, wherein the secondary substrate surface of the second substrate and the primary substrate surface of the first substrate are interconnected such that the electrode layer and the probe layer are confined within an area defined by the first substrate and the second substrate; wherein the electrode layer comprises at least a first electrode pair, the first electrode pair compType: GrantFiled: September 7, 2012Date of Patent: January 16, 2018Assignee: DANMARKS TEKNISKE UNIVERSITETInventors: Noemi Rozlosnik, Johannes Dapra
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Publication number: 20180010157Abstract: The present invention generally relates to the microbiological industry, and specifically to the production of L-serine or L-serine derivatives using genetically modified bacteria. The present invention provides genetically modified microorganisms, such as bacteria, wherein the expression of genes encoding for enzymes involved in the degradation of L-serine is attenuated, such as by inactivation, which makes them particularly suitable for the production of L-serine at higher yield. The present invention also provides means by which the microorganism, and more particularly a bacterium, can be made tolerant towards higher concentrations of serine. The present invention also provides methods for the production of L-serine or L-serine derivative using such genetically modified microorganisms.Type: ApplicationFiled: January 27, 2016Publication date: January 11, 2018Applicant: Danmarks Tekniske UniversitetInventors: Hemanshu Mundhada, Alex Toftgaard Nielsen
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Patent number: RE46937Abstract: The present invention relates to an apparatus comprising a diode laser (10) providing radiation in a first wavelength interval, a radiation conversion unit (12) having an input and an output, the radiation converter configured to receive the radiation in the first wavelength interval from the diode laser at the input, the radiation conversion unit configured to convert the radiation in the first wavelength interval to radiation in a second wavelength interval and the output configured to output the converted radiation, the second wavelength interval having one endpoint outside the first wavelength interval.Type: GrantFiled: March 8, 2016Date of Patent: July 3, 2018Assignee: DANMARKS TEKNISKE UNIVERSITETInventors: Ole Bjarlin Jensen, Peter Eskil Andersen, Paul Michael Petersen