Patents Assigned to DEVELOPMENT FOUNDATION
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Publication number: 20090124506Abstract: A method of implementation of a P-system in membrane computing comprising: placing three mutually immiscible liquids into a container, such that a first of said liquids provides a barrier between the second and third liquids; providing an initial substrate to at least one of said second and third liquids; and applying a transport rule for said first liquid to allow transport of substrate between said second and said third liquid.Type: ApplicationFiled: November 3, 2008Publication date: May 14, 2009Applicant: Technion Research & Development Foundation Ltd.Inventor: Ehud Keinan
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Publication number: 20090117149Abstract: Methods and compositions concerning mutant flaviviruses with reduced virulence. In some embodiments the invention concerns nucleotide sequences that encode mutant flaviviral proteins. Viruses comprising mutant NS1 and NS4B genes display reduced virulence are provided. In further aspects of the invention, flavivirus vaccine compositions such as West Nile virus vaccines are provided. In another embodiment the invention provides methods for vaccination against flavivirus infection.Type: ApplicationFiled: July 14, 2006Publication date: May 7, 2009Applicant: Research Development FoundationInventors: Jason A. Wicker, Melissa C. Whiteman, Alan D.T. Barrett
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Patent number: 7527999Abstract: A Cd1-xZnxS film material, with a high value of thermal coefficient of resistance, in the range of 1.5% to 3.7%. The Cd1-xZnxS material has excellent characteristics for use in a microbolometer-type uncooled infrared sensor. The film material can be deposited on microbolometer membranes or any other wafer for different applications. The film material can be deposited using the MOCVD technique, thermal evaporation or a different technique to form the film material over the wafer. The Cd1-xZnxS properties can be modified controlling certain deposition parameters and different annealing techniques. The process is performed at temperature compatible with CMOS technology.Type: GrantFiled: December 6, 2005Date of Patent: May 5, 2009Assignee: Technion Research & Development Foundation Ltd.Inventors: Sara Stolyarova, Yehuda Sinai, Moshe Weinstein, Avi Shai, Yael Nemirovsky
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Publication number: 20090112499Abstract: The device for jitter measurement and a method thereof are provided. The device for jitter measure includes a signal retrieving module, a signal amplifying module, an edge detecting module, and a time-to-digital converting module. The signal retrieving module receives a signal-under-test, and retrieves a first pulse signal having a pulse width equal to a period of the signal-under-test. The signal amplifying module amplifies the pulse width of the first pulse signal and thereby generates a second pulse signal. The edge detecting module detects a rising edge and a falling edge of the second pulse signal, and generates a first indication signal and a second indication signal according to the respective detected results. The time-to-digital converting module converts the pulse width of the second pulse signal existed in time domain to a digital signal according to the first indication signal and the second indication signal.Type: ApplicationFiled: May 8, 2008Publication date: April 30, 2009Applicants: HIMAX TECHNOLOGIES LIMITED, NCKU RESEARCH & DEVELOPMENT FOUNDATIONInventors: An-Sheng Chao, Soon-Jyh Chang, Chih-Haur Huang, Kuo-Chan Huang, Shih-Ming Luo
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Publication number: 20090109280Abstract: A method of remotely viewing a video from a selected viewpoint selected by the viewer from a continuous segment, including, recording a video of a subject using at least one depth video camera that records a video comprising a sequence of picture frames and additionally records a depth value for each pixel of the picture frames, recording a video of the subject using at least one standard video camera positioned to record a video at a viewpoint that differs from the viewpoint of the depth video camera, rendering a depth hull that defines a three dimensional outline of the subject being recorded using the depth values recorded by the depth video cameras, providing the recorded video from one or more cameras positioned on either side of the selected viewpoint, incorporating the recorded video from the one or more cameras onto the rendered depth hull to render a viewable video from the selected viewpoint; and displaying the rendered viewable video to the viewer.Type: ApplicationFiled: October 31, 2007Publication date: April 30, 2009Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.Inventors: Craig GOTSMAN, Alexander BOGOMJAKOV
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Publication number: 20090110285Abstract: The subject matter discloses a method and apparatus for re-sampling a sequence of images in order to improve its resolution, fill-in missing pixels, or de-interlace it. The method operates locally in the images to be processed, comparing pixel values of pixels surrounding the target pixel to pixel values of substantially the same locations in neighboring images. The comparison results in assigning a weight value for each area compared with the area containing the reviewed pixel. The pixel value of the reviewed pixel is updated as a function of multiplying pixel values of the areas by the weight assigned to each area. In another embodiment, areas within the same image are compared to areas containing the reviewed pixel. The subject matter also discloses two possible penalty functions for improving the resolution of images.Type: ApplicationFiled: July 24, 2008Publication date: April 30, 2009Applicant: Technion Research and Development Foundation LtdInventors: Michael ELAD, Matan Protter
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Patent number: 7520666Abstract: A system and method for detecting structural damage in a layered structure, the method compromising: providing an array of optical fibers attached to the layered structure; providing a laser source for emitting light into the optical fibers; providing a thermal imaging device; transferring laser light beam through each of the optical fibers of the array; acquiring at least one thermal image of an external surface of the layered structure; and detecting existence of one or more hot spots on the external surface indicative of a location of damage in the layered structure.Type: GrantFiled: December 7, 2006Date of Patent: April 21, 2009Assignee: Technion Research and Development Foundation Ltd.Inventors: Pavel Pevzner, Tanchum Weller, Avraham Berkovits
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Patent number: 7521209Abstract: Cleavage site for the protease furin is inserted between domains of a membrane glycoprotein. Upon cleavage by furin in the trans-Golgi network, the protein is separated into individual membrane-free domain that retains its native conformation. This protocol can be used to produce virus membrane protein domains for structural analysis and for trials as vaccines.Type: GrantFiled: February 21, 2007Date of Patent: April 21, 2009Assignee: Research Development FoundationInventor: Dennis T. Brown
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Patent number: 7519487Abstract: The alternating current potential drop ACPD technique is used to monitor surface cracks in electrical conductors. At high frequencies, the current flows in a superficial skin layer. Two distinct solutions are currently available for the thin and thick skin cases. However, there is no general solution that bridges these two modes in a seamless fashion. A numerical model is used to analyze the ACPD of a surface crack with uniform depth. A general solution is given that bridges the thin and thick skin solutions, which closely matches the numerical results, irrespective of the skin thickness. Methods for estimating depth of cracks are provided for surface penetrating cracks and back cracks.Type: GrantFiled: March 6, 2007Date of Patent: April 14, 2009Assignee: Technion Research and Development Foundation Ltd.Inventors: Hagit Saguy, Daniel Rittel
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Publication number: 20090093418Abstract: A new class of paromomycin-derived aminoglycosides, which exhibit efficient stop-codon mutation suppression activity, low toxicity and high selectivity towards eukaryotic cells are provided. Also provided are chemical and chemo-enzymatic processes of preparing these paromomycin-derived aminoglycosides and intermediates thereof, as well as pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders.Type: ApplicationFiled: October 1, 2008Publication date: April 9, 2009Applicant: Technion Research & Development Foundation Ltd.Inventors: Timor Bassov, Tamar Ben-Yosef, Igor Nudelman, Annie Rebibo-Sabbah, Dalia Shallom-Shezifi, Mariana Hainrichson
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Publication number: 20090093056Abstract: Methods of generating and expanding proliferative, multipotent connective tissue progenitor cells from adult stem cells are provided. Also provided are methods of generating functional tendon grafts in vitro and bone, cartilage and connective tissues in vivo using the isolated cell preparation of connective tissue progenitor cells.Type: ApplicationFiled: January 11, 2007Publication date: April 9, 2009Applicant: Technion Research & Development Foundation Ltd.Inventors: Joseph Itskovitz-Eldor, Shahar Cohen
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Patent number: 7509886Abstract: The invention relates to a mechanical structure which provides motion in six degrees of freedom, which comprises: (a) a main plate; (b) a base; (c) at least three supporting structures, each comprising a lower, bridge-like section supported by the base, and an upper section connected to said bridge section and to said main plate, wherein: (I) said bridge-like structure comprising two supporting plates, two intermediate plates, and one middle plate, all being serially connected one to another by means of four transversal hinges; (II) each pair of said supporting plates being slidable in linear displacement parallel to the base; (III) said upper section comprising two plates, a lower plate connected to said middle plate by means of a hinge transversal to said lower plate but longitudinal with respect to said middle plate, and an upper plate connected to said lower plate by means of a longitudinal hinge and to said main plate by means of a transversal hinge; (d) At least six linear motors connected each to a corType: GrantFiled: November 8, 2004Date of Patent: March 31, 2009Assignees: Rafael Armament Development Ltd., The Technion Research & Development Foundation Ltd.Inventors: Ronen Ben Horin, Moshe Shoham, Hagay Bamberger
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Patent number: 7507794Abstract: The present invention is directed to compositions and methods related to soluble G-protein coupled receptors (sGPCR). In ceratin aspects the invention includes compositions and methods related to a soluble corticotropin releasing factor receptor related protein, sCRFR2, as well as its effects on CRFR signaling and interaction between CRF family ligand and CRFR receptors, including but not limited to CRFR2, CRFR1 and functional or signaling capable variants thereof.Type: GrantFiled: February 8, 2006Date of Patent: March 24, 2009Assignee: Research Development FoundationInventors: Alon Chen, Marilyn Perrin, Wylie Vale
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Publication number: 20090074832Abstract: Articles of manufacturing comprising electrospun elements having continuous or stepwise gradients of porosity, average pore size, weight per volume and/or of agents for promoting cell colonization, differentiation, extravasation and/or migration are provided. Also provided are methods of manufacturing and using same for guiding tissue regeneration.Type: ApplicationFiled: April 4, 2006Publication date: March 19, 2009Applicant: Technion Research & Development Foundation Ltd.Inventors: Eyal Zussman, Erella Livne, Samer Srouji, Shmuel Chervinsky
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Patent number: 7504381Abstract: A novel class of antimicrobial polymeric agents, which include a plurality of amino acid residues, such as positively charged amino acid residues, and at least one hydrophobic residue linking there between. such as an omega-amino-fatty acid residue designed to exert antimicrobial activity while being stable, non-toxic and avoiding development of resistance thereto and a process of preparing same are disclosed. Further disclosed are pharmaceutical compositions containing same and a method of treating medical conditions associated with pathological microorganisms, a medical device, an imaging probe and a food preservative utilizing same. Further disclosed are conjugates of an amino acid residue and a hydrophobic moiety residue and a process of preparing same.Type: GrantFiled: September 26, 2005Date of Patent: March 17, 2009Assignee: Technion Research & Development Foundation Ltd.Inventors: Amram Mor, Inna Radzishevsky
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Publication number: 20090068951Abstract: A signal processing method includes sampling an analog signal, which has a spectral density defining one or more bands, to produce a digitized signal. A spectral transform of the digitized signal is expressed as a matrix multiplied by a vector, wherein the vector includes multiple elements that represent the spectral density of the analog signal as a function of frequency within respective spectral slices. Indices of a subset of the elements of the vector, in which the spectral density is concentrated, is determined. The analog signal is reconstructed from the digitized signal using the subset of the elements of the vector and a corresponding subset of columns of the matrix having the indices.Type: ApplicationFiled: January 23, 2008Publication date: March 12, 2009Applicant: Technion Research & Development Foundation Ltd.Inventors: Moshe Mishali, Eldar Yonina
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Patent number: 7494936Abstract: A method for electrochemical etching of a semiconductor material using positive potential dissolution (PPD) in solutions that do not contain hydrofluoric acid (HF-free solutions). The method includes immersing an as-cut semiconductor material in an etching solution, and positive biasing at atypically highly positive (anodic) potentials, thereby significantly increasing the value of the anodic current density (measured as A/cm2) of the semiconductor material. The application of positive biasing at atypically highly positive (anodic) potentials, is combined with specifically controlling and directing illumination on the semiconductor material surface contacted and wetted by the etching solution. This is done for a necessary and sufficient period of time to enable a positive synergistic effect on the rate and extent of etching of the semiconductor material therefrom.Type: GrantFiled: May 16, 2005Date of Patent: February 24, 2009Assignee: Technion Research & Development Foundation Ltd.Inventors: Yair Ein-Eli, David Starosvetsky, Joseph Yahalom
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Patent number: 7495514Abstract: A low noise amplifier including a first-stage signal amplifier, a second-stage signal amplifier and a gain control unit is disclosed. The first-stage signal amplifier is for receiving an input signal and outputting a first output signal accordingly. The second-stage signal amplifier is coupled to the first-stage signal amplifier for outputting a second output signal according to the first output signal. The second-stage signal amplifier includes a first output transistor for outputting the second output signal. The gain control unit includes a first variable resistance device coupled to an input terminal of the first output transistor for adjusting voltage gain of the second output signal.Type: GrantFiled: February 17, 2006Date of Patent: February 24, 2009Assignees: Himax Technologies Limited, NCKU Research and Development FoundationInventors: Da-Rong Huang, Huey-Ru Chuang, Yuan-Kai Chu
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Patent number: 7488865Abstract: The present invention provides transgenic mice deficient in urocortin. Urocortin null mutant mice are hypersensitive to stress and display heightened anxiety-like behaviors in the elevated plus maze and open field tests. These mice also demonstrate physiological alterations in auditory thresholds and distortion product otoacoustic emissions. These results indicate that urocortin plays a modulatory role in anxiety-related behaviors and in contributing to the establishment of auditory thresholds. Such urocortin deficient mutant mice can provide useful models in the study of anxiety pathology and hearing physiology at the biochemical and molecular levels.Type: GrantFiled: May 19, 2003Date of Patent: February 10, 2009Assignee: Research Development FoundationInventors: Kuo-Fen Lee, Wylie Vale, Chien Li, Lingyun Zhao, Douglas E. Vetter
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Patent number: 7489024Abstract: An array of uncooled infrared sensors based on a micro-machined temperature sensitive MOS transistor. The sensor array is fabricated using a commercial CMOS process on SOI wafers, followed by backside silicon dry etching for each sensor pixel. Active sensor pixels may include either, an integrator and buffer, or simply the sensing transistor, serving also as the selection device. The transistor bias controls the selected device and the sensitivity of the sensor. PMOS transistors and switched operation are used for noise minimization.Type: GrantFiled: February 15, 2004Date of Patent: February 10, 2009Assignee: Technion Research & Development Foundation Ltd.Inventors: Eran Socher, Oflr Bochobza-Degani, Yael Nemirovsky