Abstract: The invention relates to a method for assessing clinical activity and resistance to multiple anticancer drugs of mammalian cells, based on a dose-dependent inhibition with cytotoxic agents of the cellular rise in ornithine decarboxylase activity, following serum stimulation, which comprises the steps of: (a) determining by an immunological technique the rise in the ornithine decarboxylase protein levels, after adding serum containing medium to quiescent mammalian cells, and (b) obtaining the levels of the anticancer drug resistance from the ratio of 50% inhibitory concentration of ornithine decarboxylase obtained with an anticancer drug for drug resistant cells and drug sensitive cells. The immunological technique is selected from ELISA, radioimmunoassay, immunofluorescence, flow cytometry and fluorescence microscopy. The increase in the ornithine decarboxylase activity results from an increase in the number of ornithine decarboxylase molecules.

Abstract: R(+)-N-p-opargyl-1-aminoindan, its preparation and use and pharmaceutical compositions containing it. The novel compound was found to be useful for the treatment of human patients for Parkinson's disease, memory disorders, dementia of the Alzheimer type (DAT), depression and the hyperactive syndrome.

Abstract: The present invention provides novel DNA sequences, recombinant DNA (rDNA) molecules, processes for producing novel T-cell proteins expressed in T-cell development, the novel T-cell proteins in substantially pure form and antibodies which bind to the novel proteins. More particularly, it relates to novel DNA sequences expressed in appropriate hosts and the novel T-cell proteins produced in these hosts. The present invention also provides novel transmembrane proteins in substantially pure form, rDNA molecules encoding transmembrane proteins and processes for producing the novel transmembrane proteins.

Abstract: The invention relates to a preparation exhibiting enzymatic activity, which preparation has the capability of delignifying wood pulp at a temperature of at least 65.degree. C. and a pH of at least 9. Further, the invention relates to a method of producing said preparation by aerobically fermentating a selected Bacillus stearothermophilus strain. Furthermore, the invention relates to two isolated Bacillus stearothermophilus strains and mutants and variants thereof. The invention also relates to applications of the preparation of the invention, namely to a process comprising treatment of wood pulp with a preparation according to the invention, and a wood pulp and a fluff pulp treated with a preparation according to the invention, and also a paper, a board and a fluff made from a wood pulp treated with a preparation according to the invention.

Abstract: The measurement of gray scale or color composition integrated densities of irregularly shaped areas of a subject specimen is accomplished by using a video camera to derive an analog video image signal representative of the optical intensity of light associated with the specimen. A modified low cost high speed video digitizer converts the video image signal into a digital format which an interactive computer program converts into digital optical density values that are used to determine the net integrated density of each irregularly shaped area within the specimen.

Abstract: R(+)-N-propargyl-1-aminoindan, its preparation and use and pharmaceutical compositions containing it. The novel compound was found to be useful for the treatment of human patients for Parkinson's disease, memory disorders, dementia of the Alzheimer type (DAT), depression and the hyperactive syndrome.

Abstract: A method and apparatus for producing a frequency-controlled loop in a phase-diversity receiver for demodulating received ON-OFF-keyed (OOK) and phase shift keying (PSK) signals, by feeding a reference frequency signal and the received signals to a quadrature mixer (QM) which produces two output signals in phase quadrature at nominally zero intermediate frequency. Quadrature continuous wave signals void of the modulation are produced from the phase quadrature output signals. A voltage proportional to the frequency of the quadrature continuous wave signals is generated and is utilized for controlling the frequency of the generated reference frequency signal.

Abstract: Synthetic tRNAs are produced from tRNA.sup.Cys (AAA), tRNA.sup.Ser (AAA), tRNA.sub.e.sup.Ala (AAA), and tRNA.sub.i.sup.Ala (AAA) genes. Polyuridylic acid-dependent syntheses of polypeptides were carried out in vitro on E. coli ribosomes using the synthetic tRNAs.

Abstract: Immunogens for vaccination of mammals to prevent tick infestation and transfer of disease from ticks to host animals. The immunogens are derived from cells of pathogen-free ticks, preferably tick gut brush border cells or developing larvae cells, and provide positive responses to immunoblotting and cell mediated immune response to the host, and as well do not cause heightened cutaneous response to tick feeding.

Abstract: The invention relates to an apparatus for an efficient photodynamic therapy treatment. The apparatus comprises the following parts: (a) a lamp possessing a narrow beam light with half angle divergence up to 10.degree., possessing an intensity of at least 2 mW/nm with a spectral region in the range of 610 to 750 nm; (b) a glass lens to focus the beams of the light; (c) a red filter possessing a transmittance of 0.95 which provides a spectral region of above 610 nm, and (c) a light guide in the range of 3 to 12 mm diameter, which provides a minimum irradiance of 50 mW/cm.sup.2. According to a preferred embodiment the lamp is provided with a fixed internal reflector. In order to transmit the useful radiation and to remove the heat produced by the infra-red radiation, a 45.degree. dicroic mirror is attached to the apparatus.

Abstract: A method and apparatus for controlling an irrigation cycle of an area of soil or like material are disclosed. The irrigation cycle may stop as soon as a wetting front of the applied fluid reaches a depth Zi. The wetting front may continue downward into the soil by drainage and percolation to a predetermined final depth Zf. The irrigation cycle controlling apparatus may include an irrigation controller such as a water valve and a wetness sensor configured as a tubular rod. The wetness sensor may be composed of a plurality of porous, hydrophilic plastic material rings, which are separated from each other by a plurality of non-porous, non-conductive rings. A pair of electrodes may contact the top and bottom surfaces of each porous ring and may emit signals to a central processing unit in accordance with the degree of soil wetness. A switching circuit may be connected to the central processing unit and to each of the electrodes.

Abstract: The present invention provides a novel cDNA sequence (Pem), a gene product protein (Seq. id No. 1), and uses for this novel cDNA Sequence and the Pem gene product. The DNA sequence and recombinant DNA molecules of this invention are characterized in that each codes for a novel protein having the following characteristics: (1) is expressed by T lymphoma cells, (2) is not expressed in normal thymus, activated spleen cells, gut associated lymphoid tissue, or bone marrow, and is not detectable in adult brain, liver, large intestine or ovary, (3) is expressed in immortalized or cancerous cell lines, and (4) is expressed in embryonic development.

Abstract: The present invention provides novel DNA sequences, recombinant DNA (rDNA) molecules, processes for producing novel T-cell proteins expressed in T-cell development, the novel T-cell proteins in substantially pure form and antibodies which bind to the novel proteins. More particularly, it relates to novel DNA sequences expressed in appropriate hosts and the novel T-cell proteins produced in these hosts. The present invention also provides novel transmembrane proteins in substantially pure form, rDNA molecules encoding transmembrane proteins and processes for producing the novel transmembrane proteins.

Abstract: A method and apparatus for a contactless mode of electroreflectance (ER) which utilizes a condenser-like system, of which the front electrode is light transparent, i.e., for instance, consists of a transparent conductive coating on a transparent substrate which is separated from the sample surface by a thin layer of air. With the use of the method and apparatus of this invention, the contactless electroreflectance spectra could be measured at 300K from a number of materials including semi-insulating bulk GaAs, bulk Si, bulk Hg.sub.0.75 Cd.sub.0.25 Te, a GaAs structure with large uniform electric field and a GaAs/GaAlAs coupled double quantum well.

Abstract: A hydrophobic and oleophilic particular vermicular structure of expanded graphite, possessing the property of absorbing in a selective manner only large amounts of petroleum products from a water media is described. This expanded grahite is characterized by three main properties: (a) a specific density in the range of 0.003-0.1 g/ml; (b) a surface area in the range of 50-200 m.sup.2 g/ml; and (c) closed pores in the range of 3% to 20%. The particular structure of the expanded graphite can be used in the form of particulate, pillows, blankets, booms or as a filter medium. Preferred particles sizes of the expanded graphite are in the range of between 0.5 to 3 mm. The oil absorbed onto the expanded grahite can be released by pressure or recovered by solvent extraction.

Abstract: Novel discogens based on tricycloquinazoline derivatives and methods for their preparation are described. One method for their preparation is to nitrate veratraldehyde and after reducing the resulting nitrate to dimethoxy anthranil to obtain its trimerization thus producing a trisubstituted tricycloquinazoline. Another method is to start with dichlorotoluene and after its nitration to oxidize the nitrate into dichloronitrodiacetoxytoluene, its hydrolysis into benzaldehyde followed by a partial reduction to anthranil and finally by the trimerization of the anthranil to obtain the hexachlorotricycloquinazoline. The novel compounds are useful as fluorescent indicators for high performance oxygen sensors, organic conductors, liquid crystals and polymeric liquid crystals.

Abstract: Disclosed is a photo-deviometer by which accurate and reproducible measurements and photographs are obtained on a wide range of patients of all ages and ethnic background affected by strabismus.

Abstract: Spraying equipment for plants growing in parallel rows comprises a main horizontal air duct and several secondary ducts extending therefrom in downward direction between the rows of plants. Each duct is provided with air outlets directed towards the plants, which are alternately opened and closed by valves so as to eject the air in pulses. One spray nozzle each is positioned in the center of each air outlet serving to eject into the pulsating air stream a jet of spraying fluid which is thereby carried onto the plants covering these from top to bottom. The equipment is attached to the front or rear of a tractor which carries a supply of spraying fluid and a pump serving to supply the material to each nozzle through piping. A blower is positioned in the main duct supplying air under pressure to the secondary ducts and to the air outlets.

Abstract: The present invention provides a novel human cytokine termed Oncoinhibin. The protein Oncoinhibin is secreted by human erythroblastoid cells, has a molecular weight of approximately 28 kDa and exerts diverse neoplastic activity. The present invention also provides a method for the preparation of human Oncoinhibin.

Abstract: A method and apparatus are described for demodulating a modulated signal having a carrier component and a data component, in which the modulated signal is split into at least two parts one of which is delayed with respect to the other, and the two parts are multiply-coupled and linearly-combined to produce a combined output corresponding to a function of the data component independent of the carrier component frequency. In the described method and apparatus the undelayed part is coupled with the delayed part in a multiport coupler, wherein the parts are relatively phase-shifted to produce a plurality of phase-shifted signals; and the phase-shifted signals are linearly combined such that the data component, in the function of the combined output, is not affected by variations in frequency or phase of the carrier component. This enables a robust direct-detection DPSK receiver.