Abstract: Aqueous compositions suitable for topical administration to the human or animal eye contain at least one water-soluble polymeric ophthalmic lubricant, such as hyaluronate, carbomer gel or hypromellose, together with a water-soluble analgesic. The analgesic may be an opiod, particularly an opioid having an affinity for 5-HT receptors, such as tramadol. The aqueous compositions may for example be used as artificial tears, and as general ophthalmic lubricants for treating conditions such as dry eye or blepharitis. Further compositions combine ophthalmologicallyactive agents, such as pharmaceuticals, with opioids, such as tramadol in particular. These compositions may be used to treat the eye while reducing pain or discomfort that would normally be produced by administering these particular pharmaceuticals to the eye, and increasing the efficacy of the pharmaceuticals.

Abstract: An apparatus, method, and computer program product are provided for software development testing utilizing one or more minimal testing features. An acceptance testing system receives one or more first minimal testing features for a first software development component to be developed by a first provider, and one or more second first minimal testing features for a second software development component to be developed by a second provider. Before completion of the second software development component, it is determined whether the first software development component is complete. If it is determined that the first software development component is complete, testing is performed on the first software development component utilizing the one or more first minimal testing features, before the completion of the second software development component.

Abstract: A system, method, and computer program product are provided for testing a network service associated with a communications network. In use, a network service to be tested is identified, the network service including at least one network service associated with a communication network. Further, test criteria associated with the network service to be tested is identified. Additionally, a test scenario is generated for testing the network service based on the testing criteria.

Abstract: Disclosed are a system, apparatus, and method for prioritizing and scheduling of notifications to a user on a user device based on the user's behavior profile and user state. The method includes collecting user related data by a plurality of data collectors. The data may be collected by the user's device and a server connected to the user's device. The data collected by the user's device and the server may be different. The collected data is analyzed to generate user states data and user behavior data. The prioritizing and scheduling of the messages is done based on the user states data and the behavior data.

Abstract: A system, method, and computer program product are provided for providing security in a Network Function Virtualization based (NFV-based) communication network. In operation, a security attack is identified. Additionally, a first hardware unit attacked by the security attack is identified. Further, a hardware unit in which to initiate a security defense software program is identified. Moreover, the security defense software program is initiated in the identified hardware unit.

Abstract: A hybrid analog-digital pixel circuit is fabricated on two wafers. A first wafer includes the analog pixel circuitry and a second wafer includes the digital control and processing circuitry. Externally accessible contact structures for electrically interconnecting the two wafers are arranged in groups. Each group includes externally accessible contact structures for carrying signals associated solely with operation of a corresponding pixel.

Abstract: A system, method, and computer program product are provided for accessing data on a big data platform. In use, a request associated with a data processing job to process data stored in a big data store is identified, the data being stored in a plurality of rows with each row being associated with a unique key. Additionally, a data processing job input associated with the request is received, the data processing job input including a set of keys required to be read for processing. Further, the set of keys is translated into one or more queries, the one or more queries including at least one of a request to read an individual key or a request to read a range of keys. Moreover, the data is loaded from the big data store based on the one or more queries.

Abstract: Herein described is a topical composition for application of an NSAID, the composition comprising a solution or suspension of the NSAID as active ingredient in a residual carrier system comprising a polyhydric alcohol, a glycol ether, an ester of a higher fatty acid and water, and the ingredients of the residual carrier system have the following concentrations in percentages by weight::polyhydric alcohol 50-90%; glycol ether 7.5-40%; ester 0.5-5%; and water up to 10%. Either the composition or the residual carrier system is a single phase at ambient conditions. The composition may also comprise a volatile solvent such as ethanol or isopropyl alcohol.

Abstract: The performance and ease of management of wireless communications environments is improved by a mechanism that enables access points (APs) to perform automatic channel selection. A wireless network can therefore include multiple APs, each of which will automatically choose a channel such that channel usage is optimized. Furthermore, APs can perform automatic power adjustment so that multiple APs can operate on the same channel while minimizing interference with each other. Wireless stations are load balanced across APs so that user bandwidth is optimized. A movement detection scheme provides seamless roaming of stations between APs.

Abstract: A system, method, and computer program product are provided for planning distribution of one or more network resources in a Network Function Virtualization based (NFV-based) communication network. In use, at least one Virtual Network Function (VNF) instance of a VNF is migrated between processing units in a NFV-based communication network, according to a change of load. Further, a lack of at least one network resource associated with at least one network node is reported for planning distribution of one or more network resources in the NFV-based communication network, the missing network resource at least partially limiting migration of one or more VNF instances.

Abstract: This invention relates to novel compounds which are inhibitors of the Rearranged during Transfection (RET) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to RET dysfunction or where modulation of RET activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (IBS) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung c

Abstract: A pixel arrangement includes a photodiode, a reset transistor configured to be controlled by a reset signal and coupled to a reset input voltage, a transfer gate transistor configured to transfer charge from the photodiode to a node, wherein the transfer gate transistor is controlled by a transfer gate voltage, and a source follower transistor controlled by the voltage on the node and coupled to a source follower voltage. A capacitor is coupled between the node and an input voltage. During a read operation the input voltage is increased to boost the voltage at the node. The increased input voltage may, for example, be one the reset input voltage, said source follower voltage, said transfer gate voltage and a boosting voltage.

Abstract: An optical module for use in a device includes an array of pixels configured to capture image data and a memory. The memory is configured to store identification information associated with said optical module. The identification information enables retrieval of information for controlling said optical module from a source outside said device.

Abstract: The invention provides a global optimization and dispatching method based on time scales. The method uses a target value system and a dispatch model. The global optimization and dispatching method takes input from the results from a variety of subtopics. The methods provide adjustment and optimization in accordance with the time scales that are given in the sub goal of each sub topic: long-term, mid-long-term, short-term, ultra short term and real time optimization. Smart distribution grid can improve operational efficiency, integrated application of new elements in the distribution network of distribution energy network, micro grid, energy storage device and non-linear loads. This invention is fully adapted to the smart grid trends, with a good prospective.

Abstract: The present invention concerns the use of a population of cells comprising: (a) neural precursor cells committed to an oligodendroglial fate; (b) uncommitted neural precursor cells (c) differentiated oligodendrocytes; or (d) a combination of any one of (a) to (c) for the treatment of CNS autoimmune diseases, or for the preparation of a pharmaceutical composition for treating CNS autoimmune diseases, the population of cells being derived from human pluripotent stem cells. The invention also provides methods for obtaining such populations of cells, namely, neural precursor cells committed to an oligodendroglial fate as well as differentiated oligodendrocytes which then can be used in the treatment of CNS autoimmune diseases. A preferred autoimmune disease in the context of the present invention is multiple sclerosis where the population of cells is administered to the CNS for local treatment of the disease.

Abstract: A system, method, and computer program product are provided for selecting at least one new physical element and/or virtual element for use in a system including a network function virtualization orchestrator (NFV-O). In use, information corresponding to data traffic associated with a network system including an NFV-O module is identified, the NFV-O module being operable to manage data flow associated with one or more Virtual Network Functions (VNFs) and one or more physical elements of the network system. Additionally, an overall expected usage of the network system is determined based on the information corresponding to the data traffic. Further a cost of implementing at least one of one or more new physical elements or one or more VNFs is determined, based on the overall expected usage.

Abstract: A variator having at least one roller which runs upon at least one race to transfer drive from one to the other at variable ratio. The variator has a fluid supply for supplying fluid to the race and roller thereby to provide a fluid film by which the roller and the race are separated in use. The roller has a running surface with root means square roughness Rq(roller) and the race having a root means square roughness Rq(race). The variator's specific film thickness is the minimum thickness of the fluid film in normal operation divided by the composite roughness, and is less than 1.0. At least one of the roller and the race has a powder metal surface with a Ra roughness above 0.1 micrometers.