Patents Assigned to DexCom, Inc.
  • CONTINUOUS ANALYTE SENSORS AND METHODS OF MAKING SAME
    Publication number: 20110024043
    Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice.
    Type: Application
    Filed: July 1, 2010
    Publication date: February 3, 2011
    Applicant: DexCom, Inc.
    Inventors: Robert Boock, Jeff Jackson, Huashi Zhang, Jason Mitchell
  • Optimized sensor geometry for an implantable glucose sensor
    Patent number: 7881763
    Abstract: An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a curved portion of the body such that when a foreign body capsule forms around the sensor, a contractile force is exerted by the foreign body capsule toward the sensing region. The body is partially or entirely curved, partially or entirely covered with an anchoring material for supporting tissue ingrowth, and designed for subcutaneous tissue implantation. The geometric design, including curvature, shape, and other factors minimize chronic inflammatory response at the sensing region and contribute to improved performance of the sensor in vivo.
    Type: Grant
    Filed: May 2, 2006
    Date of Patent: February 1, 2011
    Assignee: DexCom, Inc.
    Inventors: James H. Brauker, Victoria Carr-Brendel, Paul V. Neale, Laura A. Martinson, Mark A. Tapsak
  • Biointerface membranes incorporating bioactive agents
    Patent number: 7875293
    Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: January 25, 2011
    Assignee: DexCom, Inc.
    Inventors: Mark Shults, James H. Brauker, Victoria Carr-Brendel, Mark Tapsak, Dubravka Markovic
  • SYSTEMS AND METHODS FOR PROCESSING, TRANSMITTING AND DISPLAYING SENSOR DATA
    Publication number: 20110009727
    Abstract: Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate displayable sensor information to a plurality of different types of display devices.
    Type: Application
    Filed: September 10, 2010
    Publication date: January 13, 2011
    Applicant: DexCom, Inc.
    Inventors: MICHAEL ROBERT MENSINGER, John Michael Dobbles, Apurv U. Kamath, Beat Stadelmann, Deborah M. Ruppert, Nasser Salamati, Richard C. Yang
  • PERFORMANCE REPORTS ASSOCIATED WITH CONTINUOUS SENSOR DATA FROM MULTIPLE ANALYSIS TIME PERIODS
    Publication number: 20110004085
    Abstract: A method of providing performance reports to persons associated with the monitoring of an analyte level, such as blood glucose concentrations in a host, is provided. The performance reports can indicate a measure of an analyte variability of the host over a first analysis time period compared to a measure of analyte variability of the host over one or more other analysis time periods. The analyte level of the host can be received in each of a plurality of sensor readings from a continuous analyte sensor, such as multiple sensor readings per hour, so that the analyte variability that is used in determining the performance report of the host can be based on not just a few metered readings taken by the host, but a plurality of intermittent readings that are taken by a continuous analyte sensor, for example.
    Type: Application
    Filed: April 29, 2010
    Publication date: January 6, 2011
    Applicant: DexCom, Inc.
    Inventors: Michael R. Mensinger, Deborah M. Ruppert
  • CALIBRATION TECHNIQUES FOR A CONTINUOUS ANALYTE SENSOR
    Publication number: 20100331655
    Abstract: Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
    Type: Application
    Filed: September 1, 2010
    Publication date: December 30, 2010
    Applicant: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, Peter C. Simpson, James H. Brauker, Paul V. Goode, JR.
  • CALIBRATION TECHNIQUES FOR A CONTINUOUS ANALYTE SENSOR
    Publication number: 20100331648
    Abstract: Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
    Type: Application
    Filed: September 1, 2010
    Publication date: December 30, 2010
    Applicant: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, Peter C. Simpson, James H. Brauker, Paul V. Goode, JR.
  • SYSTEMS AND METHODS FOR PROCESSING, TRANSMITTING AND DISPLAYING SENSOR DATA
    Publication number: 20100331656
    Abstract: Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate displayable sensor information to a plurality of different types of display devices.
    Type: Application
    Filed: September 10, 2010
    Publication date: December 30, 2010
    Applicant: DexCom, Inc.
    Inventors: MICHAEL ROBERT MENSINGER, John Michael Dobbles, Apurv U. Kamath, Beat Stadelmann, Deborah M. Ruppert, Nasser Salamati, Richard C. Yang
  • SYSTEMS AND METHODS FOR PROCESSING, TRANSMITTING AND DISPLAYING SENSOR DATA
    Publication number: 20100331657
    Abstract: Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate displayable sensor information to a plurality of different types of display devices.
    Type: Application
    Filed: September 10, 2010
    Publication date: December 30, 2010
    Applicant: DexCom, Inc.
    Inventors: MICHAEL ROBERT MENSINGER, John Michael Dobbles, Apurv U. Kamath, Beat Stadelmann, Deborah M. Ruppert, Nasser Salamati, Richard C. Yang
  • HOUSING FOR AN INTRAVASCULAR SENSOR
    Publication number: 20100331644
    Abstract: An apparatus houses an intravascular sensor and is configured to measure the analyte in a biological sample of a host. The apparatus includes a fluid coupler having a first end configured to mate with a connecting end of a catheter and a second end configured to mate with a tubing assembly including, for example, an infusion pump, and a housing connected to the fluid coupler. The housing is configured to receive a sensor disposed within the fluid coupler such that when the fluid coupler is mated to the catheter, the sensor can be exposed to a biological sample. The housing is also configured to electrically couple the sensor with an external device, such as a processor for receiving and analyzing the sensor output. The housing and the fluid coupler are connected such that a fluidic seal is formed thereby preventing fluid in the fluid coupler from entering the housing.
    Type: Application
    Filed: July 1, 2010
    Publication date: December 30, 2010
    Applicant: DexCom, Inc.
    Inventors: Paul V. Neale, Jake S. Leach, Peter C. Simpson, Jennifer Blackwell
  • Analyte measuring device
    Patent number: 7860545
    Abstract: An implantable analyte-measuring device including a membrane adapted to promote vascularization and/or interfere with barrier cell layer formation. The membrane includes any combination of materials, architecture, and bioactive agents that facilitate analyte transport to provide long-term in vivo performance of the implantable analyte-measuring device.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: December 28, 2010
    Assignee: DexCom, Inc.
    Inventors: Mark C. Shults, James H. Brauker, Victoria Carr-Brendel, Mark A. Tapsak, Dubravka Markovic, Stuart J. Updike, Rathbun K. Rhodes
  • Analyte sensor
    Patent number: 7857760
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: December 28, 2010
    Assignee: DexCom, Inc.
    Inventors: Mark Brister, James Brauker, J. Michael Dobbles
  • TRANSCUTANEOUS ANALYTE SENSOR
    Publication number: 20100324403
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Application
    Filed: August 27, 2010
    Publication date: December 23, 2010
    Applicant: DexCom, Inc.
    Inventors: Mark Brister, Jack Pryor, James R. Petisce, John Nolting, Jacob S. Leach, Luis Pestana, Nelson Quintana, Vance Swanson
  • TRANSCUTANEOUS ANALYTE SENSOR
    Publication number: 20100305869
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Application
    Filed: August 9, 2010
    Publication date: December 2, 2010
    Applicant: DexCom, Inc.
    Inventors: James H. Brauker, Apurv Ullas Kamath, Paul Goode, Mark Brister
  • ANALYTE SENSOR
    Publication number: 20100298684
    Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
    Type: Application
    Filed: February 26, 2010
    Publication date: November 25, 2010
    Applicant: DexCom, Inc.
    Inventors: Jacob S. Leach, Mark Brister, Sean Saint, James R. Petisce, Mark C. Shults, David K. Wong, Kum Ming Woo
  • Device and method for determining analyte levels
    Patent number: 7835777
    Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: November 16, 2010
    Assignee: DexCom, Inc.
    Inventors: Mark C. Shults, Stuart J. Updike, Rathbun K. Rhodes
  • DUAL ELECTRODE SYSTEM FOR A CONTINUOUS ANALYTE SENSOR
    Publication number: 20100286496
    Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
    Type: Application
    Filed: July 19, 2010
    Publication date: November 11, 2010
    Applicant: DexCom, Inc.
    Inventors: Peter C. Simpson, James H. Brauker, Paul V. Goode, Apurv U. Kamath, James R. Petisce, Kum Ming Woo, Melissa A. Nicholas, Robert J. Boock, Monica A. Rixman, John Burd, Rathburn K. Rhodes, Mark A. Tapsak
  • Analyte sensor
    Patent number: 7828728
    Abstract: The present invention relates generally to membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the invention relates to novel silicone-hydrophilic polymer blend membranes, and to devices and implantable devices including these membranes.
    Type: Grant
    Filed: February 14, 2007
    Date of Patent: November 9, 2010
    Assignee: DexCom, Inc.
    Inventors: Robert Boock, Monica Rixman, James H. Brauker, James R. Petisce, Peter C. Simpson, Mark Brister, Mark A. Tapsak, Victoria Carr-Brendel
  • Dual electrode system for a continuous analyte sensor
    Patent number: 7831287
    Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: November 9, 2010
    Assignee: DexCom, Inc.
    Inventors: Mark Brister, James R. Petisce, Peter Simpson
  • POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS
    Publication number: 20100280341
    Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.
    Type: Application
    Filed: March 5, 2010
    Publication date: November 4, 2010
    Applicant: DexCom, Inc.
    Inventors: Robert Boock, Monica A. Rixman, Huashi Zhang, Michael J. Estes, Kristina Lawrence