Patents Assigned to Diagnostics, Inc.
  • Patent number: 11125749
    Abstract: A system for providing colorimetric and ratiometric comparison and quantification for medical test results, comprising a testing device including an alignment target and including a plurality of immunoassay test strips, the plurality of immunoassay test strips each including a test line and a control line, and a colorimetry device configured to operate with a mobile device, the mobile device including a camera and a software application stored thereon, wherein the software application provides executable instructions to detect color properties of a color of the test line and a color of a control line of at least one of the plurality of immunoassay test strips, determine a risk value for each of at least one disease risks tested using the biologic sample, wherein the risk value is a rating determined from the color properties of the color of the test line, and provide medical test results based on the risk value.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: September 21, 2021
    Assignee: Reliant Immune Diagnostics, Inc.
    Inventors: Jovan Hutton Pulitzer, Henry Joseph Legere, III
  • Patent number: 11125737
    Abstract: A microcapillary sensor array includes a sensor body that is elongated along a longitudinal axis. The sensor body has a first end, a second end spaced from the first end along the longitudinal axis, an outer surface, and an inner surface. The inner surface defines a hollow capillary that extends from the first end toward the second end along the longitudinal axis. The microcapillary sensor array includes a sensing element that extends through the sensor body from the outer surface to the hollow capillary and a conductive element in contact with the sensing element. The conductive element detects a response signal generated by a reaction between the sensing element and a fluid as the fluid flows through the hollow capillary contacting the sensing element.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: September 21, 2021
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: Jennifer Samproni
  • Publication number: 20210282709
    Abstract: Devices, kits, and methods for (a) determining the presence and/or concentration of at least one analyte(s) of interest present in a patient's fluid sample and devices and methods of calibration related thereto, and (b) preventing, mitigating, and/or eliminating biofouling of an indwelling, wearable biosensor are disclosed and/or claimed herein.
    Type: Application
    Filed: June 7, 2017
    Publication date: September 16, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: David Ledden
  • Publication number: 20210285868
    Abstract: A method and system is described that includes obtaining a whole blood sample and obtaining a first light absorbance profile of the whole blood sample. Next, the whole blood sample is hemolyzed to generate a hemolyzed sample of blood and a second light absorbance profile of the hemolyzed sample of blood is obtained. The level of hemolysis in the whole blood sample is determined by comparing the first light absorbance profile and the second light absorbance profile.
    Type: Application
    Filed: June 7, 2017
    Publication date: September 16, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Jeffrey Jasperse
  • Publication number: 20210283594
    Abstract: An embodiment of the present disclosure is a sample vessel for a holding a sample for analysis by a sample analyzer. The sample vessel includes a body that includes a bottom, an open top spaced from the bottom along a first axis, a side wall that extends from the open top to the bottom, and an interior chamber for holding a sample and that extends from the open top toward the bottom along the first axis. The body includes an opaque portion, a first translucent portion, and a second translucent portion spaced from the first translucent portion a distance that extends along a second axis that is perpendicular to the first axis. The first and second translucent portions are each disposed along the bottom of the body.
    Type: Application
    Filed: July 17, 2017
    Publication date: September 16, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Jeffrey Jasperse, Normand Desmarais
  • Publication number: 20210287789
    Abstract: Methods of troubleshooting non-event malfunctions. The methods include providing a database including pre-populated non-event issues and associated corrective actions, inputting search criteria regarding a particular non-event issue via entry of a search string at the user interface, parsing and normalizing the search string into a meta-data schema to produce a normalized search string, searching the database with the normalized search string to generate a listing of one or more particular corrective actions, and receiving the listing of one or more particular corrective actions that are associated with the normalized search string. Apparatus configured to carry out the methods are provided, as are other aspects.
    Type: Application
    Filed: July 24, 2017
    Publication date: September 16, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Arnold Rudorfer, Steven Magowan, Joel Cambron
  • Publication number: 20210285945
    Abstract: Devices, kits, and methods for determining the presence or absence of at least one analyte in a liquid test sample.
    Type: Application
    Filed: June 7, 2017
    Publication date: September 16, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: David LEDDEN, Lloyd SCHULMAN
  • Patent number: 11118219
    Abstract: The technology relates in part to methods and compositions for isothermal amplification of nucleic acids.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: September 14, 2021
    Assignee: Nat Diagnostics, Inc.
    Inventors: Andrew P. Miller, Honghua Zhang
  • Patent number: 11119108
    Abstract: Methods and reagents are disclosed for preparing a liquid solution of a receptor. The methods comprise combining in a liquid medium the receptor, a chelating agent and a C2-C6 polyol. An amount of the chelating agent and the C2-C6 polyol is sufficient to achieve a stable and active receptor in the liquid solution, which is maintained at a temperature of about 2° C. to about 40° C. The compositions may be employed in assays for the determination of analytes that include receptor-binding analytes.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: September 14, 2021
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: David Kiaei
  • Publication number: 20210278412
    Abstract: The present invention relates to the detection and quantitative measurement of proteins with the Coomassie Brilliant Blue Assay with improved sensitivity and maintaining high linearity over a broad measuring range. In particular the present invention relates to a method of detecting a protein in a protein-containing sample, comprising providing a sample comprising a protein, a reagent comprising Coomassie Brilliant Blue, combining the sample and the reagent and determining of the absorption to determine the amount of protein in the sample, wherein the pH-value of the reagent is between pH-value 0.85 and pH-value 1.1, and the ratio of the absorption value at a first wavelength of between about 580 to 620 nm to the one at a second wavelength of between about 520 to 370 nm is used in the spectral photometric determination of the amount of protein.
    Type: Application
    Filed: August 10, 2017
    Publication date: September 9, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Frank Vitzthum, Herbert Schwarz, Anja Haude-Barten
  • Publication number: 20210269879
    Abstract: This invention relates to methods and compositions for assessing the suitability of a graft for transplantation or implantation by measuring total and/or specific cell-free nucleic acids (such as cf-DNA) and/or cell lysis. Specifically, the method comprising obtaining an amount of total cf DNA and/or graft-specific cfDNA released from a potential graft (e.g., ex vivo), e.g., prior to contacting of the potential graft with blood cells of a potential recipient, and/or subsequent to contacting of the potential graft or cells thereof with blood cells from a potential recipient, assessing the amount(s) to determine the suitability of the potential graft for transplantation or implantation.
    Type: Application
    Filed: December 14, 2018
    Publication date: September 2, 2021
    Applicant: TAI Diagnostics, Inc.
    Inventors: Aoy Tomita Mitchell, Michael Mitchell
  • Publication number: 20210270849
    Abstract: Methods of detecting and flagging and/or suppressing aberrant results caused by incomplete dispersion of an immunoassay reagent used in a turbidimetric immunoassay are disclosed.
    Type: Application
    Filed: June 28, 2019
    Publication date: September 2, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Tie Wei
  • Publication number: 20210270820
    Abstract: Nanodiamond particles and related devices and methods, such as nanodiamond particles for the detection and/or quantification of analytes, are generally described. In some embodiments, the device comprises a plurality of nanodiamond particles and a species bound to the nanodiamond particles. In certain embodiments, the plurality of nanodiamond particles may be exposed to a sample suspected of containing an analyte. In some cases, the analyte may bind to the species such that the presence of the analyte in the sample may be detected. In some embodiments, the devices, systems, and methods described herein are useful for the detection of an analyte in a sample obtained from a subject for, for example, diagnostic purposes. In some cases, the systems, devices, and methods described herein may be useful for diagnosing, prevent, treating, and/or managing a disease or bodily condition.
    Type: Application
    Filed: May 10, 2021
    Publication date: September 2, 2021
    Applicant: Debina Diagnostics, Inc.
    Inventors: Giora Z. Feuerstein, Mark E. Sternberg
  • Patent number: 11106028
    Abstract: An optical microscopy device for detecting cellular components of a sample, includes: a light source apparatus for emitting a light beam; a specimen carrier, which can be positioned in the beam path of the light beam, for receiving the sample; an objective lens which is provided downstream of the specimen carrier in the beam path of the light beam; and a camera chip which has pixels of a predefined pixel size, the camera chip being designed to detect the light beam after it passes through the objective lens and being designed to generate a camera image, a field number in the intermediate image downstream of the objective lens being greater than 25 millimeters.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: August 31, 2021
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Thomas Engel, Oliver Schmidt
  • Patent number: 11103173
    Abstract: An electrocardiography patch is provided. A pair of electrodes are exposed on a contact surface of a flexible backing. A circuit includes a pair of circuit traces and each circuit trace is electrically coupled to one of the electrodes in the pair. A plurality of electrical pads are positioned between the electrodes and above at least a portion of the circuit traces. A pair of the electrical pads interface with the electrodes. A pair of battery leads electrically interface a battery to another pair of the electrical pads.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: August 31, 2021
    Assignee: Bardy Diagnostics, Inc.
    Inventors: Jon Mikalson Bishay, Gust H. Bardy, Jason Felix
  • Publication number: 20210264650
    Abstract: A data display includes a grid including: a first column configured to display particular data values of a first data parameter; a plurality of rows, each row configured to display a particular data value of the first data parameter in the first column; and a second column including a vertically-extending graph, wherein the particular data value in one or more of the plurality of rows is plotted as a data point horizontally aligned with a corresponding row on the vertically-extending graph, wherein a plurality of data points display moving data values of the first data parameter.
    Type: Application
    Filed: August 28, 2019
    Publication date: August 26, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Dariusz Tarnawski
  • Patent number: 11096579
    Abstract: A system and method for remote ECG data streaming in real-time is provided. ECG data is encrypted on a physiological monitor placed on a patient via a near-field communication chip on the physiological monitor. A continuous connection is established between the physiological monitor and a cloud-based server via a wireless transceiver on the physiological monitor. The encrypted ECG data is transmitted from the physiological monitor to the cloud-based server. The ECG data is then transmitted from the cloud-based server to a device associated with a medical professional in real-time.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: August 24, 2021
    Assignee: Bardy Diagnostics, Inc.
    Inventors: Ezra M. Dreisbach, Gust H. Bardy
  • Publication number: 20210255200
    Abstract: Measurement of circulating ST2 and/or IL-33 concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e.g., mortality, and the detection of severe disease.
    Type: Application
    Filed: April 27, 2021
    Publication date: August 19, 2021
    Applicant: Critical Care Diagnostics, Inc.
    Inventors: James V. Snider, Sven Jacobson
  • Patent number: 11091807
    Abstract: The present invention provides assay systems and methods for detection of copy number variation at one or more loci and polymorphism detection at one or more loci in a mixed sample from an individual.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: August 17, 2021
    Assignee: Ariosa Diagnostics, Inc.
    Inventors: Andrew Sparks, Arnold Oliphant, Jacob Zahn, Ken Song, John Stuelpnagel
  • Publication number: 20210247398
    Abstract: Kits containing a chemiluminescent detection system and microfluidics devices and methods for determining the concentration of biotin in a sample are disclosed. The kits, microfluidics devices, and methods utilize a sensitizer capable of generating singlet oxygen in its excited state and having avidin or an analog thereof directly or indirectly bound thereto, as well as a singlet oxygen-activatable chemiluminescent compound having biotin or an analog thereof directly or indirectly bound thereto.
    Type: Application
    Filed: July 24, 2019
    Publication date: August 12, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Tie Q. Wei, Zhu Teng, Xiaodong Liu, Martin Drinan