Patents Assigned to Dipharma S.p.A.
  • Clopidogrel salts with alkyl-sulphuric acids
    Publication number: 20040132765
    Abstract: Clopidogrel salts with alkyl-sulphuric acids, having the following formula (I) 1
    Type: Application
    Filed: October 17, 2003
    Publication date: July 8, 2004
    Applicants: DINAMITE DIPHARMA S.P.A., ABBREVIATED DIPHARMA S.P.A.
    Inventors: Graziano Castaldi, Alberto Bologna, Domenico Magrone
  • Process for the preparation of high purity Pemirolast
    Patent number: 6703505
    Abstract: A novel process for the purification of Pemirolast, whose potassium salt is an anti-allergic pharmaceutical product, is disclosed.
    Type: Grant
    Filed: July 17, 2002
    Date of Patent: March 9, 2004
    Assignee: Dinamite Dipharma S.p.A.
    Inventors: Graziano Castaldi, Erminio Oldani
  • Process for the preparation of high purity pemirolast
    Publication number: 20030032805
    Abstract: A novel process for the purification of Pemirolast, whose potassium salt is an anti-allergic pharmaceutical product, is disclosed.
    Type: Application
    Filed: July 17, 2002
    Publication date: February 13, 2003
    Applicant: DINAMITE DIPHARMA S.P.A.
    Inventors: Graziano Castaldi, Erminio Oldani
  • Process for the preparation of terbinafine
    Patent number: 6515181
    Abstract: A process for the preparation of terbinafine which comprises the reaction of tert-butylacetylene with a compound of formula (II) characterized in that the reaction is carried out in the presence of copper (I) salts and of a base, in the absence of palladium.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: February 4, 2003
    Assignee: Dipharma S.p.A.
    Inventors: Graziano Castaldi, Giuseppe Barreca, Renzo Rossi
  • Process for the preparation of 2-(4-methylphenyl)-benzoic acid derivatives
    Patent number: 6433214
    Abstract: A process for the preparation of 2-(4-methylphenyl)benzoic acid C1-6alkyl esters by reaction of a sulfonic derivative of formula wherein R is C1-6alkyl and R1 is optionally perfluorinated C1-6alkyl or optionally substituted C1-6aryl, with a 4-methylphenylzinc halide.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: August 13, 2002
    Assignee: Dipharma S.p.A.
    Inventors: Graziano Castaldi, Antonio Tarquini, Renzo Rossi
  • Process for the preparation of 2-phenyl-imidazo [1, 2-a] pyridine-3-acetamides
    Patent number: 6384226
    Abstract: A process for the preparation of 2-phenyl-imidazo[1,2-a]pyridine-3-acetamides comprises the reaction of a 2-phenyl-imidazo[1,2-a]pyridine with an oxalic ester reactive derivative, followed by reduction of the carbonyl group and reaction with an amine.
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: May 7, 2002
    Assignee: Dinamite Dipharma S.p.A.
    Inventor: Graziano Castaldi
  • Process for the preparation of 2-phenyl-imidazo [1, 2-a] pyridine-3-acetamides
    Publication number: 20020019528
    Abstract: A process for the preparation of 2-phenyl-imidazo[1,2-a]pyridine-3 -acetamides comprises the reaction of a 2-phenyl-imidazo[1,2-a]pyridine with an oxalic ester reactive derivative, followed by reduction of the carbonyl group and reaction with an amine.
    Type: Application
    Filed: July 12, 2001
    Publication date: February 14, 2002
    Applicant: DINAMITE DIPHARMA S.p.A.
    Inventor: Graziano Castaldi
  • Process for the purification of (RR,SS)-2-(dimethylamino) methyl-1-(3-methoxyphenyl)-cyclohexanol from (RS,SR)-2-(dimethylamino)methyl-1-(3-methoxyphenyl) cyclohexanol
    Patent number: 6169205
    Abstract: A process for the purification of (RR,SS)-2-(dimethylamino)methyl-1-(3-methoxyphenyl)cyclohexanol, which comprises the selective precipitation of (RR,SS)-2-(dimethylamino)methyl-1-(3-methoxyphenyl)cyclohexanol in the presence of (RS,SR)-2-(dimethylamino)methyl-1-(3-methoxyphenyl)cyclohexanol from a solvent consisting of water and a water-miscible organic solvent.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: January 2, 2001
    Assignee: Dipharma S.p.A.
    Inventors: Walter Cabri, Domenico Magrone