Abstract: The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders.
Type:
Application
Filed:
August 31, 2010
Publication date:
August 23, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Preparation and isolation of amino vinyl cyclopropane carboxylic acid derivatives and salts thereof, methods of resolving enantiomers, and methods of identifying compositions and/or enzymes that are capable of resolving racemic or partially enantiomerically enriched mixtures.
Type:
Application
Filed:
January 2, 2012
Publication date:
May 31, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Ian N. Taylor, Michael C. Lloyd, Adrian Heseltine
Abstract: The application relates to processes for preparing fipamezole and its pharmaceutically acceptable salts, and intermediates thereof. It also provides intermediate compounds of Formula III and Formula IV, and processes for their preparation.
Type:
Application
Filed:
January 31, 2012
Publication date:
May 24, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Ranjan Bhowmik Dipal, Lingam Yedugani, Raghavndra Rao Kamaraju, Subba Rao Jammula, Swapna Manikonda, Vilas H. Dahanukar
Abstract: Methods of producing compositions of trans-4-amino-2-cyclopentene-1-carboxylic acid derivatives are described. Also described is an amine salt of a compound having formula A, having components present in both cis and trans structures.
Type:
Application
Filed:
January 2, 2012
Publication date:
April 26, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Richard Lloyd, Justine Ann Peterson, Mark Jackson
Abstract: A hydrate of esomeprazole magnesium in the form of an amorphous solid is provided. Methods of preparation and use of, as well as formulation containing the hydrate of esomeprazole magnesium in the form of an amorphous solid are also provided.
Type:
Grant
Filed:
September 28, 2009
Date of Patent:
March 13, 2012
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
Abstract: The present application relates to processes for the preparation and purification of decitabine structurally represented by formula (I): and to processes for the preparation of a crystalline form of decitabine.
Type:
Application
Filed:
October 27, 2011
Publication date:
February 23, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Pharmaceutical formulations comprising multiple drugs, for treating or preventing cardiovascular disease. Embodiments are capsules containing individual drugs, or combinations of drugs, in the form of small tablets.
Type:
Application
Filed:
October 28, 2011
Publication date:
February 23, 2012
Applicants:
Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Ltd.
Abstract: Substantially non-porous polymeric microparticles comprising a hydrophobic polymer and a plasticizer, and containing therein a bioactive or bioinactive agent.
Type:
Application
Filed:
October 17, 2011
Publication date:
February 16, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LIMITED
Abstract: The present application provides novel thiazole derivatives that are useful as activators of Adenosine 5?-Monophosphate-Activated Protein Kinase and pharmaceutical compositions containing such compounds.
Type:
Grant
Filed:
June 30, 2006
Date of Patent:
December 20, 2011
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
Abstract: A 5(S)-(2?-hydroxyethoxy)-20(S)-camptothecin diasterisomer is described which is a better inhibitor of topoisomerase I than either the diastereoisomeric mixture 5(RS)-(2?-hydroxyethoxy)-20(S)-camptothecin, or the 5(R)-(2?-hydroxyethoxy)-20(S)-camptothecin diastereoisomer. Pharmaceutical compositions of the 5(S)-(2?-hydroxyethoxy)-20(S)-camptothecin diastereoisomer are also described as are methods of using the compound for the inhibition of topoisomerase I and for the treatment of cancer.
Type:
Grant
Filed:
October 12, 2009
Date of Patent:
December 20, 2011
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
Abstract: Controlled release pharmaceutical compositions comprising ropinirole or pharmaceutically acceptable salts thereof, wherein embodiments have ropinirole embedded in a matrix comprising one or more polymers, and the composition in monolithic form or in multiparticulate form.
Type:
Application
Filed:
August 14, 2008
Publication date:
November 24, 2011
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LIMITED
Abstract: A process for preparing crystalline Form A of tadalafil (I), comprising crystallization from a solution of tadalafil in a solvent comprising a C3-C7 ester, a ketone, dimethylformamide, dimethylsulfoxide, ethanol, acetonitrile, a chlorinated hydrocarbon, t-butanol, N,N-dimethylacetamide, dioxane, N-methyl pyrrolidone, or a mixture of any two or more thereof.
Type:
Grant
Filed:
October 26, 2005
Date of Patent:
November 22, 2011
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
Inventors:
Eswaraiah Sajja, Venkata Naga Kali Vara Prasada Raju Vetukuri, Srinivas Reddy Ningam, Ravindra Vedantham, Rajyalakshmi Bodepudi
Abstract: Eszopiclone is prepared by reacting zopiclone with an enatiomerically pure di-p-toluoyl tartaric acid, recovering a solid salt, and reacting a solid salt with a base. Zopiclone is prepared by reacting 6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]-pyrazine with 1-chlorocarbonyl-4-methylpiperazine hydrochloride.
Type:
Grant
Filed:
December 19, 2008
Date of Patent:
November 15, 2011
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.,
Abstract: The present invention relates to docetaxel and processes for preparing docetaxel, including process-related intermediates. The present invention also relates to processes for preparing substantially pure docetaxel and intermediates.
Type:
Application
Filed:
May 20, 2011
Publication date:
November 10, 2011
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Substantially non-porous polymeric microparticles comprising a hydrophobic polymer and a plasticizer, and containing therein a bioactive or bioinactive agent.
Type:
Grant
Filed:
June 5, 2006
Date of Patent:
November 8, 2011
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.,
Abstract: There is provided a process for preparing 21-acetyloxy-6-alpha-fluoro-pregna-1,4,9(11),16-tetraene-3,20-dione compound of Formula I, which comprises reacting 21-acetyloxy-pregna-1,3,5,9(11),16-pentaene-3-oxo acetate with a fluorinating agent.
Type:
Grant
Filed:
March 21, 2008
Date of Patent:
November 1, 2011
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
Inventors:
Sergio Ferrino, Diego Torres, Vilas Dahanukar