Abstract: A process for preparation of crystalline Form I of clopidogrel hydrogen sulphate, that include separating the crystalline Form I of clopidogrel hydrogen sulphate from a solution of clopidogrel freebase in a solvent, which is 2-propanol or 2-butanol is provided.
Type:
Grant
Filed:
March 11, 2005
Date of Patent:
August 10, 2010
Assignees:
Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Limited
Abstract: Solid pharmaceutical formulations are prepared using compositions comprising orlistat and having average particle sizes less than about 250 ?m.
Type:
Application
Filed:
September 17, 2008
Publication date:
August 5, 2010
Applicants:
DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
Inventors:
Soma Sekhar Kothamasu, Arti Sah, Uma Sowjanya Asapu, Maheswara Reddy Arumalla
Abstract: Processes for preparing substantially pure docetaxel, new crystalline forms of docetaxel and processes for preparation thereof, processes for preparing docetaxel trihydrate, and pharmaceutical compositions comprising docetaxel.
Type:
Application
Filed:
July 3, 2008
Publication date:
August 5, 2010
Applicants:
DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
Abstract: The present invention provides crystalline polymorphs of docetaxel and processes for preparing them, a method for preparing amorphous docetaxel, and a process for preparing docetaxel.
Type:
Application
Filed:
March 20, 2007
Publication date:
June 24, 2010
Applicants:
DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
Abstract: Compositions and/or formulations comprising solifenacin or a salt thereof and processes for preparing the same. Certain compositions and formulations contain a stable amorphous form of solifenacin succinate.
Type:
Application
Filed:
April 11, 2008
Publication date:
June 3, 2010
Applicants:
DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
Abstract: The present invention is related to novel polymorph of Fexofenadine and Fexofenadine hydrochloride of formula 1 and process of preparation thereof. The present invention is also directed to provide pure novel polymorphs of Fexofenadine and its hydrochloride by a simple process which is cost effective, commercially viable and environment friendly.
Type:
Grant
Filed:
July 31, 2001
Date of Patent:
April 20, 2010
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
Inventors:
M. Satyanarayana Reddy, S. Thirumalai Rajan, U. V. Bhaskara Rao
Abstract: There is provided a solid dispersion of imatinib mesylate that includes imatinib mesylate and a pharmaceutically acceptable carrier, wherein said carrier is a cellulose derivative. Also provided is a process for making a solid dispersion and a process for making imatinib.
Type:
Application
Filed:
March 12, 2008
Publication date:
April 8, 2010
Applicants:
DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
Abstract: A pharmaceutical dosage form for treating or preventing cardiovascular events comprises therapeutic amounts of: a ?-adrenergic receptor antagonist, a diuretic, or both; a cholesterol-lowering agent; an inhibitor of the renin-angiotensin system; and aspirin.
Type:
Application
Filed:
November 19, 2009
Publication date:
March 18, 2010
Applicants:
DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
Abstract: There is provided a compound, which is dehydroabietylamine salt of rosuvastatin. Also provided are processes for making rosuvastatin calcium that include formation of dehydroabietylamine salt of rosuvastatin.
Type:
Application
Filed:
November 29, 2007
Publication date:
March 18, 2010
Applicants:
DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
Inventors:
Satyanarayana Bollikonda, Sridhar Chaganti, Ranga Reddy Tamma, Loka Maheshwari Pochaiah h Dommati
Abstract: A process for preparation of montelukast or a salt thereof is provided, the process including reacting a late intermediate compound which is 2-[1-[1-R-3-[2-(7 chloro quinolin-2-yl)vinyl [phenyl]-3-[2-methoxy carbonyl phenyl]propyl sulfonyl methyl]cyclo propyl]acetic acid or a salt thereof with methyl magnesium chloride or methyl magnesium bromide in an organic solvent. In one embodiment, the process includes reacting an earlier intermediate compound which is methyl 2-(3-R-(3-(2-(7-chloro 2-quinolinyl)-ethenyl)-3 hydroxy propyl)benzoate with methane sulfonyl chloride or toluene sulfonyl chloride to obtain a mesylated or tosylated derivative of the earlier intermediate compound; followed by a reaction of the mesylated or tosylated derivative with 1-mercapto methyl cyclopropane acetic acid in a polar solvent in a presence of a base to obtain the late intermediate compound.
Type:
Application
Filed:
November 17, 2009
Publication date:
March 11, 2010
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LIMITED
Abstract: Duplex coating schemes and associated methods of formation, including a siloxane-based soft coating and a plasma-based SiOxCy hard coating used in combination to improve the durability of polymeric substrates.
Type:
Application
Filed:
April 4, 2008
Publication date:
March 11, 2010
Applicants:
DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
Abstract: The present invention relates to pharmaceutical formulations of atorvastatin or its pharmaceutically acceptable salts, solvates, hydrates, enantiomers, polymorphs or their mixtures; and processes for preparing the same, and their methods of use, treatment and administration. Further, the present invention relates to pharmaceutical compositions comprising an acid-solubility-enhanced form of atorvastatin or its salts.
Type:
Application
Filed:
September 27, 2007
Publication date:
February 4, 2010
Applicants:
DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
Abstract: A hydrate of esomeprazole magnesium in the form of an amorphous solid is provided. Methods of preparation and use of, as well as formulation containing the hydrate of esomeprazole magnesium in the form of an amorphous solid are also provided.
Type:
Application
Filed:
September 28, 2009
Publication date:
January 21, 2010
Applicants:
DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
Abstract: The present invention relates to solifenacin in solid form and a process for its preparation and to a process for the preparation of (1S)-1-Phenyl-1,2,3,4-tetrahydro-isoquinoline, a key intermediate in the synthesis of solifenacin and its salts.
Type:
Application
Filed:
July 18, 2007
Publication date:
December 31, 2009
Applicants:
Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc.
Abstract: A hydrate of esomeprazole magnesium in the form of an amorphous solid is provided. Methods of preparation and use of, as well as formulation containing the hydrate of esomeprazole magnesium in the form of an amorphous solid are also provided.
Type:
Grant
Filed:
August 28, 2003
Date of Patent:
November 3, 2009
Assignees:
Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.