Abstract: A charger for a motor vehicle and to a method for charging an energy store of the motor vehicle.

Abstract: A method for generating driving instructions for the driver of an electrically driven vehicle includes the following steps: (a) acquire route information for at least one route section of a driving route lying ahead of the vehicle, (b) determine temperature information, acting in a temperature-varying fashion on at least one drive component, for the at least one route section on the basis of the route information, and (c) output a driving instruction to the driver on the basis of the temperature information for the at least one route section.

Abstract: This mixing machine comprises a mixing head that attaches to a container, forming a closed mixing receptacle. The head is pivotably supported in a frame such that the closed mixing receptacle can pivot to perform the mixing. The mixing head also has a rotationally driven tool which cleans the bottom of the head, supplying a low-energy transport stream for material to at least one second tool carried by the head. The second tool performs the mixing and is located inside the movement path of the bottom-cleaning first tool. The first tool has a scoop positioned in the direction of rotation of the tool with its edge facing in the direction of rotation and outward in the radial direction. The first tool comprises a first scoop section, a second, wall-cleaning scoop section and a recess open toward its closure more remote from the wall through which the second tool passes during rotation of the first tool.

Abstract: Parenteral (injectable) celecoxib emulsions and nanoemulsions are disclosed as are their use to treat pain in patients so afflicted. The emulsions are generally oil in water emulsions often comprised of an oil phase including an oil and a lecithin wherein the mean droplet size of the discontinuous oil phase is about 200 nanometers or less.

Abstract: The invention relates to a method for regulating the temperature of the calibration volume of an apparatus for comparative calibration of temperature sensors to a target temperature, wherein said calibration device comprises heat sources and/or heat sinks, which are in thermal contact via a heat conducting part or a plurality of heat conducting parts with the calibration volume, wherein in at least one process step the real thermal state is calculated, wherein the Kalman filter is fed the measurement values of a temperature sensor located in the calibration device, and in at least one more process step the future thermal state is calculated using a thermal model of the dynamics of states.

Abstract: Apparatus, methods, and computer-readable media are provided for segmentation, processing (e.g., preprocessing and/or postprocessing), and/or feature extraction from tissue images such as, for example, images of nuclei and/or cytoplasm. Tissue images processed by various embodiments described herein may be generated by Hematoxylin and Eosin (H&E) staining, immunofluorescence (IF) detection, immunohistochemistry (IHC), similar and/or related staining processes, and/or other processes. Predictive features described herein may be provided for use in, for example, one or more predictive models for treating, diagnosing, and/or predicting the occurrence (e.g., recurrence) of one or more medical conditions such as, for example, cancer or other types of disease.

Abstract: A method for transmitting electric power and signals between a wall and a leaf pivotally mounted on the wall. The method includes transmitting the electric power so as to be galvanically isolated, and transmitting the signals optically or optoelectronically.

Abstract: The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine, particularly in pain therapy.

Abstract: An electric axle drive has a transmission arrangement with two gears, with an electric machine for driving two output shafts of the axle of the motor vehicle, a first spur gear stage which can be driven by the electric machine for driving an intermediate shaft and a planetary carrier of a planetary gear mechanism, which planetary carrier is connected fixedly to the intermediate shaft and receives planetary gears, and with an internal gear of the planetary gear mechanism for driving a second spur gear stage, a sun gear of the planetary gear mechanism and shifting elements for shifting the two gears. A first shifting element is configured as a clutch, by way of which the internal gear and the sun gear or the internal gear and the planetary carrier or the sun gear and the planetary carrier can be connected in a torque-transmitting manner.

Abstract: An inductive position-measuring device for absolute position determination includes a scale having a first measuring graduation extending in a measurement direction and a second measuring graduation disposed opposite to the first measuring graduation and extending parallel thereto. A scanner is disposed in a gap between the first measuring graduation and the second measuring graduation. The scanner is displaceable relative to the scale in the measurement direction for purposes of position measurement. The scanner includes a first coil arrangement for scanning the first measuring graduation and generating a first position-dependent scanning signal, and a second coil arrangement, disposed opposite to the first coil arrangement, for scanning the second measuring graduation and generating a second position-dependent scanning signal. At least one intermediate layer of soft magnetic material disposed between the first coil arrangement and the second coil arrangement.

Abstract: The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders.

Abstract: A rollover protective device (1) for a passenger vehicle has a supporting device (3) extending in the vertical elevation (2) when installed correctly. A crossbar (5) is fastened to the supporting device (3) and extends in a lateral direction (4) when installed correctly. The crossbar (5) is of beam-shaped design and is formed by a sheet metal construction (6) with a deformed front side and/or upper side (7, 8) and an inner supporting structure (9).

Abstract: A wheel suspension for the rear axle of a vehicle has a wheel carrier for fastening a rear wheel. A link system including at least two links is fastened on the wheel carrier to enable fastening on a vehicle body of the vehicle. The wheel carrier has a link portion for direct or indirect mounting on the vehicle body of the vehicle.

Abstract: The present invention is related to a method for risk detection, diagnosis, prognosis and monitoring of Alzheimer's disease (AD). The method comprises the steps of: (1) measuring the level of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) in a sample from the subject, and (2) comparing the level of GAPDH in the sample with two or more AD reference levels of GAPDH.

Abstract: An aseptic fluid connector having a male connector and a female connector engageable to aseptically transfer fluid therethrough. The male connector includes a closure and a piercing member comprising a hollow shaft for receiving fluid therein, a tip, and at least one port in fluid communication with the interior of the hollow shaft for passage of the fluid therethrough. The closure and/or the shaft is movable between (i) a first position wherein the closure closes the port(s), and (ii) a second position opening the port(s). The female connector includes a pierceable septum. The male and female connector are engageable such that the piercing member pierces the pierceable septum. Only when the pierceable member has fully penetrated the pierceable septum can the closure and/or the shaft move from the first position, to the second position to aseptically transfer fluid therethrough.

Abstract: The present invention relates to an in vitro method for determining HIV neutralizing antibodies in a sample. It further relates to a fusion protein to be used in said method and a nucleic acid encoding said fusion protein.