Abstract: A hybrid drive (1) for a vehicle has an internal combustion engine (2), an electric machine (26) and a double clutch transmission (5) with a hollow first input shaft (9) and a second input shaft (11) that penetrates the first input shaft (9). A hollow transmission shaft (15) is parallel to the input shafts (9, 11), and a drive torque can be applied to the first or second input shafts (9, 11) via the internal combustion engine (2) and/or the electric machine (26) via the double clutch (5) of the double clutch transmission (10). The electric machine (26) is outside the double clutch transmission (10), and an output shaft (25) of the electric machine (26) penetrates the hollow transmission shaft (15). As a result, a compact configuration is ensured.

Abstract: A pharmaceutical dosage form for treating or preventing cardiovascular events comprises therapeutic amounts of: a ?-adrenergic receptor antagonist, a diuretic, or both; a cholesterol-lowering agent; an inhibitor of the renin-angiotensin system; and aspirin.

Abstract: The present invention refers to new indanyl sulphonamide compounds with general formula (I), as well as to their preparation procedure, their application as medicine and the pharmaceuticals composition which they are made up of. The new compounds of formula (I) show affinity for 5-HT6 receptors and are, therefore, effective for treating diseases mediated by these receptors.

Abstract: In the case of a vehicle door with an inside door part and an outside door part which are connected to an inner and outer door shaft reinforcing device, a mirror base of a vehicle exterior rearview mirror is held at a corner of the door. The mirror base is supported on a reinforcing element arranged within the vehicle door. The reinforcing element is arranged between a support of the outer door shaft reinforcing device and a further support of the inner door shaft reinforcing device.

Abstract: A method and device are provided for limiting, in a first operating condition, a motor vehicle internal-combustion engine torque. The operating condition, resulting from an operation of a motor vehicle brake, when the engine torque is simultaneously demanded by a driver's intention indicator, differs from a second operating condition, in which the brake is not operated. The limiting takes place at least partially by way of a controlled reduction of an advance angle efficiency in the first operating condition in comparison to the second operating condition.

Abstract: In an angle-measurement system and a method for producing an angle-measurement system, the angle-measurement system includes a bearing assembly and a scanning head, the bearing assembly including a graduated ring, an outer ring and rolling bodies. Rolling surfaces are formed both on the graduated ring and the outer ring, the rolling surface of the graduated ring having a smaller path radius than that of the outer ring. Furthermore, the rolling surface of the outer ring is arranged opposite the rolling surface of the graduated ring, and the rolling bodies are disposed between the two rolling surfaces such that the bearing assembly is free of radial play. In addition, an angle scaling is applied directly onto the graduated ring such that a geometrical pattern of the angle scaling in a first region deviates from a geometrical pattern in a second region as a function of rotational eccentricities of the bearing assembly. The angle scaling is able to be scanned by the scanning head.

Abstract: Duplex coating schemes and associated methods of formation, including a siloxane-based soft coating and a plasma-based SiOxCy hard coating used in combination to improve the durability of polymeric substrates.

Abstract: A 5(S)-(2?-hydroxyethoxy)-20(S)-camptothecin diasterisomer is described which is a better inhibitor of topoisomerase I than either the diastereoisomeric mixture 5(RS)-(2?-hydroxyethoxy)-20(S)-camptothecin, or the 5(R)-(2?-hydroxyethoxy)-20(S)-camptothecin diastereoisomer. Pharmaceutical compositions of the 5(S)-(2?-hydroxyethoxy)-20(S)-camptothecin diastereoisomer are also described as are methods of using the compound for the inhibition of topoisomerase I and for the treatment of cancer.

Abstract: A battery arrangement (1) has at least two battery cell packs (2, 3) arranged in a common battery housing (4). The battery housing (4) has at least one first opening (5) for supplying cooling air and at least one second opening (6) for discharging heated air. The battery cell packs (2, 3) are arranged one above the other and delimit a tunnel (7) therebetween in a height direction. At least one of the first and second openings (5, 6) is arranged substantially at the same level as the tunnel (7). The tunnel (7) is closed at a side facing one of the first and second openings (5, 6) so that air flowing between the first and second openings (5, 6) is channeled through or around the battery cell packs (2, 3).

Abstract: A process for preparation of montelukast or a salt thereof is provided, the process including reacting a late intermediate compound which is 2-[1-[1-R-3-[2-(7 chloro quinolin-2-yl)vinyl [phenyl]-3-[2-methoxy carbonyl phenyl]propyl sulfonyl methyl]cyclo propyl]acetic acid or a salt thereof with methyl magnesium chloride or methyl magnesium bromide in an organic solvent. In one embodiment, the process includes reacting an earlier intermediate compound which is methyl 2-(3-R-(3-(2-(7-chloro 2-quinolinyl)-ethenyl)-3 hydroxy propyl)benzoate with methane sulfonyl chloride or toluene sulfonyl chloride to obtain a mesylated or tosylated derivative of the earlier intermediate compound; followed by a reaction of the mesylated or tosylated derivative with 1-mercapto methyl cyclopropane acetic acid in a polar solvent in a presence of a base to obtain the late intermediate compound.

Abstract: A front structure of a motor vehicle has a lower bumper that runs in the vehicle transverse direction, and an upper bumper arranged above the lower bumper. The lower bumper and upper bumper are supported on the vehicle structure via crash boxes. The lower bumper defines a closed hollow profile and is supported on a front-end body, in particular on a luggage compartment depression, of the motor vehicle via the associated crash boxes.

Abstract: The method relates to the production of essentially pyrogene-free calcium phosphate starting from one or more calcium phosphate educts having a Ca/P molar ratio in the range of 1.00 to 2.00 and being formed in a pre-determined shape which remains essentially the same during the following procedural steps: A) transforming said educt(s) at least partly to beta-tricalcium phosphate (?-TCP), alpha-tricalcium phosphate (?-TCP), tetracalciumphosphate.(TetCP) or a mixture thereof at a temperature above 600° C.; B) cooling down the material obtained in step A with said ?-TCP, ?-TCP, TetCP or a mixture thereof to below 600° C.; C) reacting the material obtained in step B with said ?-TCP, ?-TCP, TetCP or a mixture thereof with water in gas or liquid phase or in an aqueous Solution at a temperature above room temperature to obtain an end-product which is essentially pyrogene-free.

Abstract: A bearing structure of a motor vehicle has at least two opposite node elements. Each of the node elements has at least one longitudinal beam segment and one transverse beam connection. A transverse beam joins the transverse beam connections to each other. A profiled transverse beam segment emerges from each transverse beam connection. The transverse beam segments are joined together by a glue connection in an overlap segment, and at least one open beam profile is set thereon to form the transverse beam.

Abstract: A hydraulic cement based on calcium phosphate for surgical use comprising A) a first component comprising powder particles of calcium phosphate; and B) a second component comprising water. The calcium phosphate comprises anhydrous, amorphous calcium phosphate (ACP) and the ACP is obtained by milling a calcium phosphate synthesized above 500° C. The cement according to the invention has the advantage of being very fast setting compared to prior art calcium phosphate cements. The setting reaction is finished much faster although the initial part of the reaction proceeds at the same speed as with known cements.

Abstract: A drive unit in a motor vehicle is mounted with two elastic motor mounts, of which each in each case couples an engine support, connected rigidly to the drive unit, elastically to a body structure of the motor vehicle, and with a torque support which is arranged above the two motor mounts transversely with respect to the vehicle longitudinal axis and which is coupled at one end to the drive unit and is coupled at another end to the body structure and is configured such that the two ends are connected, damped elastically, to one another. There is also provided a damping support arranged at a lower level than the torque support transversely with respect to the vehicle longitudinal axis and which is coupled at one end to the drive unit and is coupled at another end to the body structure. The damping support is configured such that transverse vibrations of the drive unit are damped.

Abstract: A headlamp for vehicles has at least one illumination device with one or more light-emitting diodes and with an optical system that is disposed in the light exit area and focuses the light of the light-emitting diodes for a forward lighting of the vehicle. At least one cooling body is provided for dissipating the heat output by the light-emitting diode, and the cooling body contains a number of cooling ribs. To configure the light cone, the cooling body is disposed in the optical axis of the light exit area of the light-emitting diodes between the light-emitting diodes and the optical system, at least the tip of a cooling rib of the cooling body is located at the focal point between the light-emitting diode and the optical system.