Abstract: This invention relates to a process for producing solid formulations. These solid formulations comprise therapeutically active or nutritious plant extracts, which are known for being bad-tasting. These new solid formulation are neutral in taste. Furthermore the present invention relate to these solid formulations as well as to their use in the production of food, feed, nutritional supplement and personal care products.
Type:
Grant
Filed:
September 9, 2016
Date of Patent:
April 21, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Markus Beck, Andrea Bulbarello, Kevin Prudence, Loni Schweikert, Kai Urban
Abstract: The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention relates to a CRISPR-CAS system for a yeast host cell.
Type:
Grant
Filed:
January 6, 2016
Date of Patent:
April 14, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
René Verwaal, Bernard Meijrink, Nathalie Wiessenhaan, Brenda Vonk, Johannes Andries Roubos
Abstract: In the steam pelleting of feed components which include starch, the addition of an alpha-amylase to the raw material meal can reduce energy consumption (energy input) in the feed press, and increase the throughput (capacity per hour), and it may be possible to reduce the temperature in the pellet press.
Type:
Grant
Filed:
June 24, 2014
Date of Patent:
April 14, 2020
Assignees:
Novozymes A/S, DSM IP Assets B.V.
Inventors:
Christel Thea Joergensen, Anders Viksoe-Nielsen, Dan Pettersson
Abstract: The present invention relates to a polymer fiber made of a polyamide composition comprising a semi-crystalline semi-aromatic polyamide (PPA), wherein the PPA consists of repeat units derived from aromatic dicarboxylic acid comprising at least 80 mole % of terephthalic acid, relative to the total amount of aromatic dicarboxylic acid and diamine comprising at least 5 mole % of a first diamine and at least 5 mole % of a second diamine relative to the total amount of diamine; and 0-5 mole % of other monomeric units, relative to the total amount of aromatic dicarboxylic acid, diamine and other monomeric units, wherein the PPA has a melting temperature (Tm) of at least 310° C. measured by the DSC method according to ISO-11357-1/3, 2011 and with a heating rate of 10° C./min.
Type:
Grant
Filed:
January 12, 2015
Date of Patent:
April 7, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Pim Gerard Anton Janssen, Alexander Antonius Marie Stroeks
Abstract: Processes for making high-performance polyethylene multi-filament yarn are disclosed which include the steps of a) making a solution of ultra-high molar mass polyethylene in a solvent; b) spinning of the solution through a spinplate containing at least 5 spinholes into an air-gap to form fluid filaments, while applying a draw ratio DRfluid; c) cooling the fluid filaments to form solvent-containing gel filaments; d) removing at least partly the solvent from the filaments; and e) drawing the filaments in at least one step before, during and/or after said solvent removing, while applying a draw ratio DRsolid of at least 4, wherein in step b) each spinhole comprises a contraction zone of specific dimension and a downstream zone of diameter Dn and length Dn with Ln/Dn of from 0 to at most 25, to result in a draw ratio DRfluid=DRsp*DRag of at least 150, wherein DRsp is the draw ratio in the spinholes and DRag is the draw ratio in the air-gap, with DRsp being greater than 1 and DRag at least 1.
Type:
Grant
Filed:
August 8, 2017
Date of Patent:
April 7, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Joseph Arnold Paul Maria Simmelink, Jacobus Johannes Mencke, Martinus Johannes Nicolaas Jacobs, Roeloef Marissen
Abstract: The invention relates to a variant polypeptide having lactase activity. The invention also relates to a nucleic acid sequence encoding such a variant polypeptide, to a nucleic acid construct comprising said nucleic acid sequence, to a recombinant expression vector comprising said nucleic acid construct and to a recombinant host cell comprising said expression vector. Further, the invention relates to a method for producing a lactase variant via use of such a host cell. Also, the invention relates to a method of producing a lactase polypeptide variant. The invention further relates to a composition comprising a lactase variant, to use of such a lactase variant or to the use of a lactase variant-containing composition in the preparation of a dairy product, to a process for the production of a dairy product and to the resulting dairy product.
Type:
Grant
Filed:
May 4, 2018
Date of Patent:
April 7, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
René Marcel De Jong, Ulrike Maria Müller, Petrus Jacobus Theodorus Dekker
Abstract: The present invention relates to the use of novel promoters for heterologous gene expression, preferably for expression of genes in organisms of the genus Yarrowia, to the genetically modified organisms of the genus Yarrowia, and to a process for producing biosynthetic products by cultivating the genetically modified organisms.
Type:
Grant
Filed:
January 29, 2015
Date of Patent:
April 7, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Jessica Leigh McGrath, Bastien Chevreux, Peter Scott Yorgey
Abstract: The invention relates to the use of at least one bacterial amylase in combination with a mixture of at least two essential oil compounds selected from the group consisting of thymol, eugenol, meta-cresol, vaniline and guajacol in feed for ruminant animals of the subfamily Bovinae for improving weight gain, milk yield and/or Feed Conversion Ratio (FCR). Examples of bovine animals are beef cattle and dairy cows.
Type:
Grant
Filed:
February 12, 2016
Date of Patent:
April 7, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Tiago Acedo, Irmgard Immig, Luis Tamassia
Abstract: The present invention is directed to a new process for supplementation of beverages with soluble and bio available iron in the form of ferric pyrophosphate. This process allows iron supplementation of beverages at low cost, without affecting either the original taste or the colour of the beverages. It is also directed to a concentrate ferric pyrophosphate-citrate solution and its use in the preparation of an iron enriched beverage. The invention also relates to a beverage obtainable by this process.
Abstract: The invention relates to a cell capable of converting one or more pentose sugar and one or more hexose sugar into fermentation product constitutively expressing one or more heterologous or homologous polypeptide having the amino acid sequence set out in SEQ ID NO: 20, or a variant polypeptide thereof having at least 45% identity to SEQ ID NO 20. In an embodiment the heterologous polypeptide has glyoxalase activity.
Type:
Grant
Filed:
March 13, 2019
Date of Patent:
March 31, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Maria Bernedina Elizabeth Jonkers, Paul Klaassen, Aloysius Wilhelmus Rudolphus Hubertus Teunissen, Rene Marcel De Jong
Abstract: The present invention relates to a process for preparing a yeast hydrolysate comprising less than 100 ppm gluten and at least 1 ppm gluten based on salt-free yeast dry matter.
Abstract: The present invention relates to a recombinant host comprising a recombinant nucleic acid sequence encoding a polypeptide having at least about: a. 85% identity to the amino acid sequence set forth in SEQ ID NO: 1; b. 85% identity to the amino acid sequence set forth in SEQ ID NO: 3; c. 85% identity to the amino acid sequence set forth in SEQ ID NO: 6; d. 85% identity to the amino acid sequence set forth in SEQ ID NO: 9; e. 85% identity to the amino acid sequence set forth in SEQ ID NO: 11; f. 85% identity to the amino acid sequence set forth in SEQ ID NO: 14; g. 85% identity to the amino acid sequence set forth in SEQ ID NO: 17; h. 85% identity to the amino acid sequence set forth in SEQ ID NO: 20; i. 85% identity to the amino acid sequence set forth in SEQ ID NO: 22; or j. 85% identity to the amino acid sequence set forth in SEQ ID NO: 25.
Type:
Grant
Filed:
March 16, 2016
Date of Patent:
March 31, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Viktor Marius Boer, Johannes Gustaaf Ernst Van Leeuwen, Priscilla Zwartjens, Catharina Petronella Antonia Maria Kolen
Abstract: Liquid radiation curable compositions are disclosed which are suitable for hybrid (i.e. cationic and free-radical) polymerization when processed via additive fabrication equipment utilizing sources of actinic radiation with peak spectral intensities in the UV/vis region. Also disclosed are methods of creating three-dimensional parts via additive fabrication processes utilizing sources of actinic radiation with peak spectral intensities in the UV/vis region employing liquid radiation curable compositions suitable for hybrid polymerization, and the parts cured therefrom.
Type:
Grant
Filed:
June 8, 2016
Date of Patent:
March 31, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Tai Yeon Lee, Luke Kwisnek, Johan Jansen
Abstract: The present invention relates to a thermoplastic composition comprising: a) a polyamide component comprising at least three amide monomer units and b) a stabilizer characterized in that at least one of the at least three amide monomer units is an aliphatic amide monomer unit having a carbon to nitrogen ratio (C/N) equal to, or above 6.5, in that at least two of the at least three amide monomer units are semi-aromatic amide monomer units which polymerized provide at least one semi-crystalline semi-aromatic polyamide having a melting temperature of at least 290° C. as measured by DSC at a heating rate of 10° C./min according to standard ISO 1 1357-3 (2009), and in that the amount of aliphatic amide monomer unit is in the range from 20 to 60 wt. % relative to the total weight of the at least three amide monomer units in the polyamide components and the total amount of semi-aromatic amide monomer units is in the range from 40 to 80 wt.
Type:
Grant
Filed:
September 29, 2015
Date of Patent:
March 24, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Zhujuan Wang, Johannes Hoekstra, Pim Gerard Anton Janssen
Abstract: The invention relates to a process for the preparation of a fermentation product from lignocellulosic material, comprising the following steps: a) optionally, pre-treatment of the lignocellulosic material, b) optionally, washing of the optionally pretreated lignocellulosic material, c) enzymatic hydrolysis of the optionally washed and/or optionally pretreated lignocellulosic material using an enzyme composition comprising at least two cellulases and whereby the enzyme composition at least comprises LPMO, and optionally purifying the hydrolyzed lignocellulosic material, d) fermentation of the hydrolyzed lignocellulosic material to produce a fermentation product, and e) optionally, recovery of a fermentation product, wherein oxygen is consumed in amounts corresponding to between 20 and 5000 mmol molecular oxygen per kg glucan present in the lignocellulosic material, the oxygen is added after the pretreatment and before and/or during the enzymatic hydrolysis of the lignocellulosic material, preferably in an a
Type:
Grant
Filed:
October 29, 2018
Date of Patent:
March 24, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Bertus Noordam, Michael Petrus Jozef Berkhout
Abstract: The present invention relates to polyethylene material that has a plurality of unidirectionally oriented polyethylene monolayers cross-plied and compressed at an angle to one another, each polyethylene monolayer composed of ultra high molecular weight polyethylene and essentially devoid of resins. The present invention further relates to ballistic resistant articles that include or incorporate the inventive polyethylene material and to methods of preparing the material and articles incorporating same.
Abstract: The present invention relates to a process for preparing a granular nylon salt material, wherein an aqueous mixture, comprising at least 65 wt. % of salt components, and at most 35 wt. % of an aqueous medium, the weight percentages (wt. %) being relative to the total weight of the aqueous mixture, is flashed from a pressure vessel via a flash valve into a flash chamber, thereby evaporating the aqueous medium in an amount sufficient to result in a residual moisture content of at most 7.5 wt. %, and forming a granular nylon salt material. The invention also relates to a process for preparing a nylon polymer, comprising direct solid state polymerization of the granular salt material prepared by flash granulation.
Type:
Grant
Filed:
July 24, 2015
Date of Patent:
March 17, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Bas Van Laarhoven, Eric Grolman, Michiel Muyris
Abstract: The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention relates to a CRISPR-CAS system for a lipolytic yeast host cell.
Type:
Grant
Filed:
January 6, 2016
Date of Patent:
March 17, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Bernard Meijrink, René Verwaal, Bianca Elisabeth Maria Gielesen, Johannes Andries Roubos
Abstract: The present invention relates to a new process for the preparation of ammeline and/or ammelide from melamine by a solid-to-solid reaction in an aqueous reaction mixture comprising a biocatalyst, wherein the biocatalyst comprises at least one enzyme belonging to the amidohydrolase superfamily and having aminohydrolase activity towards 1,3,5-triazine compounds. The invention further relates a product obtainable by the process according to the invention, wherein the product comprises ammeline and/or ammelide.
Type:
Grant
Filed:
November 19, 2014
Date of Patent:
March 17, 2020
Assignee:
DSM IP ASSETS B.V.
Inventors:
Petronella Catharina Raemakers-Franken, Renier Henricus Maria Kierkels