Patents Assigned to DSM
  • Patent number: 9994994
    Abstract: Hybrid rope (20) comprising a core element (22) containing high modulus fibers surrounded by at least one outer layer (24) containing wirelike metallic members (26). The core element (22) is coated (23) with a thermoplastic polyurethane or a copolyester elastomer, preferably the copolyester elastomer containing soft blocks in the range of 10 to 70 wt %. The coated material (23) on the inner core element (22) is inhibited to be pressed out in-between the wirelike members (26) of the hybrid rope (20) and the hybrid rope (20) has decreased elongation and diameter reduction after being in use.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: June 12, 2018
    Assignees: BRIDON INTERNATIONAL LTD., DSM IP ASSETS B.V.
    Inventors: Xavier Amils, Beste Durmus, Paulus Johannes Hyacinthus Marie Smeets
  • Patent number: 9994828
    Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: June 12, 2018
    Assignees: Dow AgroSciences LLC, DSM IP Assets B.V.
    Inventors: Terence A. Walsh, Daniel J. Gachotte, Cory M. Larsen, Scott Bevan, P. Ann Owens-Merlo, James G. Metz, Ross Zirkle
  • Patent number: 9994837
    Abstract: The invention relates to a variant polypeptide having lactase activity. The invention also relates to a nucleic acid sequence encoding such a variant polypeptide, to a nucleic acid construct comprising said nucleic acid sequence, to a recombinant expression vector comprising said nucleic acid construct and to a recombinant host cell comprising said expression vector. Further, the invention relates to a method for producing a lactase variant via use of such a host cell. Also, the invention relates to a method of producing a lactase polypeptide variant. The invention further relates to a composition comprising a lactase variant, to use of such a lactase variant or to the use of a lactase variant-containing composition in the preparation of a dairy product, to a process for the production of a dairy product and to the resulting dairy product.
    Type: Grant
    Filed: January 13, 2015
    Date of Patent: June 12, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: René Marcel De Jong, Ulrike Maria Müller, Petrus Jacobus Theodorus Dekker
  • Patent number: 9993515
    Abstract: The present invention relates to a process to produce a composition comprising water-soluble peptides and having a Trp/LNAA ratio of more than 0.15, which comprises hydrolyzing lysozyme, preferably hen eggs lysozyme, to prepare a hydrolysate having a DH of between 5 and 45.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: June 12, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Andre Leonardus De Roos, Luppo Edens, Rudolf Franciscus Van Beckhoven, Alexander Lucia Leonardus Duchateau, Joris Kloek
  • Patent number: 9987638
    Abstract: Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: June 5, 2018
    Assignee: DSM IP ASSETS, B.V.
    Inventors: John E. Nash, William T. Fisher, Douglas G. Evans
  • Patent number: 9988649
    Abstract: The present invention relates to processes for producing ethanol from lignocellulosic hydrolysates comprising hexoses, pentoses and acetic acid, whereby genetically modified yeast cells are use that comprise an exogenous gene encoding an acetaldehyde dehydrogenase and a bacterial gene encoding an enzyme with NAD+-linked glycerol dehydrogenase activity. The process is further characterized in that glycerol is present in or fed into the culture medium, whereby the modified yeast cell ferments the hexoses, pentoses, acetic acid and glycerol to ethanol. The invention further relates to yeast cells for use in such processes. The yeast cells advantageously comprise genetic modifications that improve glycerol utilization such as modifications that increase one or more of dihydroxyacetone kinase activity and transport of glycerol into the cell.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: June 5, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Adrianus Maria De Bont, Aloysius Wilhelmus Rudolphus Hubertus Teunissen, Paul Klaassen, Wouter Willem Antonius Hartman, Shimaira Van Beusekom
  • Patent number: 9986751
    Abstract: This invention relates to the use of the Aspergillus niger aspergilloglutamic peptidase in a feed composition containing cereals, pulses, oilseeds, and/or tubers to improve animal performance, reduce nitrogen excretion and/or reduce intestinal inflammation. Furthermore, the present invention relates to a feed composition or a feed additive comprising the Aspergillus niger aspergilloglutamic peptidase. The present invention relates to the discovery that the Aspergillus niger aspergilloglutamic peptidase is capable of efficiently hydrolyzing alpha-amylase/trypsin inhibitors that are present in wheat, barley and related cereal species, as well as hydrolyzing trypsin inhibitors that are present in pulses, oilseeds, and tubers.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: June 5, 2018
    Assignees: DSM IP ASSETS B.V., NOVOZYMES A/S
    Inventors: Maaike Johanna Bruins, Luppo Edens, Helena Maria Nan
  • Patent number: 9988615
    Abstract: The invention relates to a polypeptide having hemicellulase activity. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional protein and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: June 5, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Alrik Pieter Los, Rene Marcel De Jong, Maaike Appeldoorn
  • Patent number: 9980898
    Abstract: The invention relates to a polymer composition suitable for high-heat application comprising: a. At least one polymer 1 having a solubility parameter ?P1; b. A thermo-releasable substance being a liquid at 200° C. and having a solubility parameter ?sub in an amount of at least 0.1 wt % with respect to the total amount of composition; and wherein the amount of thermo-releasable substance is in the range from 0.5 wt % to 70 wt % with respect to the polymer 1; wherein ?=(?sub??P1)2 is in the range from 0.5 to 24.0 and wherein the solubility parameter is calculated by the software package Synthia, Materials Studio v.6.0.0 ©2011, based on the method by J. Bicerano, Prediction of Polymer Properties, Marcel Dekker, 3rd Ed, 2002, ISBN 0-8247-0821-0; Chapter 5, and in which the E-modulus of the composition as measured according to method ISO 527-1 at 200° C. is at least 50 MPa. The invention also relates to personal care devices and hair-straighteners comprising this polymer composition.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: May 29, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Travis Baughman, Robin Elisabeth Maria Jacobus Daenen, Alexander Antonius Marie Stroeks, Franciscus Johannes Marie Derks, Pieter Gijsman
  • Patent number: 9981935
    Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of a specific type and of at least one Bransted acid or in the presence a specific chiral compound having a Bransted acid functional group in the molecule.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: May 29, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Jonathan Alan Medlock, Ulla Letinois, Thomas Netscher, Werner Bonrath
  • Patent number: 9980889
    Abstract: The present invention relates to the use of p-hydroxybenzylamine or a salt thereof as antimicrobial agent as well as to composition comprising said agent.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: May 29, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Christine Mendrok-Edinger, Rainer Voegeli, Peter Wikstroem
  • Patent number: 9982280
    Abstract: The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; d) whereby less than 7.5 mg enzyme composition/g glucan (on dry matter and enzyme as protein) or less than 3.0 mg enzyme composition/g feedstock (on dry matter and enzyme as protein) is used; and e) fermentation of the hydrolysed ligno-cellulosic material to produce a fermentation product; and f) optionally recovery of a fermentation product; wherein before and/or during the enzymatic hydrolysis oxygen is added to the ligno-cellulosic material.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: May 29, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bertus Noordam, Michael Petrus Jozef Berkhout
  • Patent number: 9981061
    Abstract: An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may include, or have blended in, an additive, such as an osteoinductive factor, for example biocompatible ceramics and glass.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: May 29, 2018
    Assignee: DSM IP ASSETS, B.V.
    Inventors: Douglas G. Evans, Scott M. Goldman, Russell T. Kronengold
  • Publication number: 20180134986
    Abstract: The present invention relates to a polypeptide having phospholipase C activity, selected from the group consisting of i. a polypeptide comprising a mature polypeptide sequence of SEQ ID NO: 2; ii. a polypeptide that has least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identity to the mature polypeptide sequence of SEQ ID NO: 2; iii. a polypeptide encoded by a nucleic acid that hybridizes under medium stringency, preferably under high stringency conditions to the complementary strand of the mature polypeptide coding sequence of SEQ ID NO:1; iv. a polypeptide encoded by a nucleic acid that has at least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or 100% identity to the mature polypeptide coding sequence of SEQ ID NO: 1.
    Type: Application
    Filed: April 8, 2016
    Publication date: May 17, 2018
    Applicant: DSM IP ASSETS B.V.
    Inventors: Arjen SEIN, Rene Marcel DE JONG, Evert Tjeerd VAN RIJ, Willem BIJLEVELD, Maarten Hotse WILBRINK
  • Publication number: 20180135066
    Abstract: The invention provides recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms as well as products obtained from such organisms.
    Type: Application
    Filed: July 26, 2012
    Publication date: May 17, 2018
    Applicants: DSM IP ASSETS B.V., DOW AGROSCIENCES LLC
    Inventors: Terence A. Walsh, Daniel Gachotte, Ann Owens Merlo, Dayakar Reddy Pareddy, James Metz, Scott Bevan, Jerry Kuner
  • Patent number: 9968578
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: May 15, 2018
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Patent number: 9968120
    Abstract: Disclosed are homogenized formulations that comprise microcapsules, wherein the microcapsules comprise an agglomeration of primary microcapsules and a loading substance, where each individual primary microcapsule has a primary shell, and the loading substance is encapsulated by the primary shell, and wherein the agglomeration is encapsulated by an outer shell. Also, disclosed are methods of making and using homogenized formulations by providing a pre-homogenized composition comprising one or more microcapsules and then homogenizing the composition. Some specific homogenization processes described are ultrasonic and pressure-based homogenizations.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: May 15, 2018
    Assignee: DSM NUTRITIONAL PRODUCTS AG
    Inventors: Jonathan Michael Curtis, Wei Zhang, Sharon Ann Spurvey, Suzelle Rejeanne Robert
  • Patent number: 9963549
    Abstract: The present invention relates to a poly (ester amide) (PEA) having a chemical formula described by structural formula (IV), wherein m+p varies from 0.9-0.1 and q varies from 0.1 to 0.9 m+p+q=1 whereby m or p could be 0 n is about 5 to about 300; (pref. 50-200) R1 is independently selected from the group consisting of (C2-C20) alkylene, (C2-C20) alkenylene, —(R9—CO—O—R10—O—CO—R9)—, —CHR11—O—CO—R12—COOCR11— and combinations thereof; R3 and R4 in a single backbone unit m or p, respectively, are independently selected from the group consisting of hydrogen, (C1-C6)alkyl, (C2-C6)alkenyl, (C2-C6)alkynyl, (C6-C10)aryl, (C1-C6)alkyl, —(CH2)SH, —(CH2)2S(CH3), —CH2OH, —CH(OH)CH3, —(CH2)4NH3+, —(CH2)3NHC(?NH2+)NH2, —CH2COOH, —(CH2)COOH, —CH2—CO—NH2, —CH2CH2—CO—NH2, —CH2CH2COOH, CH3—CH2—CH(CH3)—, (CH3)2—CH—CH2—, H2N—(CH2)4—, Ph-CH2—, CH?C—CH2—, HO-p-Ph-CH2—, (CH3)2—CH—, Ph-NH—, NH—(CH2)3—C—, NH—CH?N—CH?C—CH2—.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: May 8, 2018
    Assignee: DSM IP ASSETS, B.V.
    Inventors: Guy Draaisma, George Mihov
  • Patent number: 9957643
    Abstract: The invention relates to a process for producing gel-spun ultra high molecular weight polyethylene (UHMWPE) fibres having high tensile strengths and improved creep rates wherein the UHMWPE used in said process is characterized by a difference in the phase angle according to Formula 1 ??=?0.001??100??(1) of at most 42°, wherein ?0.001 is the phase angle at an angular frequency of 0.001 rad/sec; and ?100 is the phase angle at an angular frequency of 100 rad/sec as measured with a frequency sweep dynamic rheological technique at 150° C. on a 10% solution of UHMWPE in paraffin oil, provided that ?100 is at most 18°. The invention further relates to gel-spun UHMWPE fibres produced thereof. The gel-spun UHMWPE fibres of the invention have a tensile strength of at least 4 GPa, and a creep rate of at most 5×10?7 sec?1 as measured at 70° C. under a load of 600 MPa.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: May 1, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Joseph Arnold Paul Maria Simmelink, Paulus Antonius Maria Steeman
  • Patent number: D818964
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: May 29, 2018
    Assignee: DSM&T Company, Inc.
    Inventor: Sergio Corona