Abstract: The invention relates to a process for the preparation of a sugar product from ligno-cellulosic material, comprising the following steps: a) optionally pre-treatment of the ligno-cellulosic material; b) optionally washing of the optionally pre-treated ligno-cellulosic material; c) enzymatic hydrolysis of the optionally washed and/or optionally pre-treated ligno-cellulosic material using an enzyme composition comprising at least two cellulase and whereby the enzyme composition at least comprises GH61; and d) optionally recovery of a sugar product; wherein during part of the time of the enzymatic hydrolysis, oxygen is added to the ligno-cellulosic material and during part of the time of the enzymatic hydrolysis less oxygen is added to the ligno-cellulosic material compared to the other part of the time of the enzymatic hydrolysis, preferably no oxygen is added to the ligno-cellulosic material.
Type:
Grant
Filed:
November 7, 2013
Date of Patent:
May 1, 2018
Assignee:
DSM IP ASSETS B.V.
Inventors:
Bertus Noordam, Michael Petrus Jozef Berkhout, Aida Hiseni
Abstract: The present invention relates to amphiphilic block copolymers comprising reduction sensitive biodegradable polyesteramides. The present invention also relates to micelles comprising the amphiphilic block copolymers. The invention also relates to drug delivery systems comprising the micelles. The amphiphilic block copolymers comprise hydrophilic and hydrophobic blocks whereby the hydrophobic blocks comprise a biodegradable polyesteramide based on alpha-amino acids, diols, aliphatic dicarboxylic acids and optionally diamines whereby at least one of the dicarboxylic acids, diols or diamines comprises disulphide linkages.
Abstract: The invention relates to a method for modification of a host cell at a target locus, which method comprises: providing a host cell comprising, at a first locus, at least two site-specific recombination sites and a nucleic acid having an essential function or encoding a product having an essential function; introducing into the host cell, at the target locus, a further nucleic acid having the essential function or encoding for a product having the essential function; and carrying out recombination at the first locus via the at least two site-specific recombination sites, so that the nucleic acid having an essential function or encoding a product having an essential function is rendered non-functional, thereby to modify the host cell at the target locus. The invention also relates to a cell obtainable by a method of the invention.
Type:
Grant
Filed:
September 19, 2013
Date of Patent:
April 24, 2018
Assignee:
DSM IP ASSETS B.V.
Inventors:
Ilse De Lange, Bernard Meijrink, Johannes Andries Roubos, Siew-loon Ooi
Abstract: Matrix-filled liquid radiation curable resin compositions for additive fabrication are described and claimed. Such resins include a cationically polymerizable component that is an aliphatic epoxide, a multifunctional (meth)acrylate component, a cationic photoinitiator, a free-radical photo initiator, and a matrix of inorganic fillers, wherein the matrix further constitutes prescribed ratios of at least one microparticle constituent and at least one nanoparticle constituent. Also described and claimed is a process for using the matrix-filled liquid radiation curable resins for additive fabrication to create three dimensional parts, and the three-dimensional parts made from the liquid radiation curable resins for additive fabrication.
Type:
Grant
Filed:
November 25, 2015
Date of Patent:
April 24, 2018
Assignee:
DSM IP ASSETS, B.V.
Inventors:
Mingbo He, Beth Rundlett, Kangtai Ren, Caroline Liu, Tai Yeon Lee, Brad Seurer, Robin Papachristopoulos
Abstract: The present invention relates to a high-heat-delivery device suitable for use in an hair straightener, a hair curling iron or an ironing apparatus and suitable for heat transfer to a substrate by direct contact with said substrate, comprising at least one element (A) having a heat transfer contact surface area and at least one element (B) having a heat transfer contact surface, wherein the element (A) comprises a thermoconductive thermoplastic polymer composition comprising at least one polymer and a thermoconductive additive and wherein element (B) comprises a thermoplastic polymer composition comprising a polymer and at least one thermo-releasable substance. Further, the present invention relates to a method for releasing a thermo-releasable substance. Furthermore, the present invention relates to an ironing apparatus, a hair straightener and a hair curling iron comprising the high-heat delivery device.
Type:
Grant
Filed:
August 29, 2014
Date of Patent:
April 24, 2018
Assignee:
DSM IP ASSETS B.V.
Inventors:
Travis Baughman, Robin Elisabeth Maria Jacobus Daenen, Alexander Antonius Marie Stroeks, Franciscus Johannes Marie Derks, Pieter Gijsman
Abstract: The present invention relates to the use of a specific organic compound as flavor and fragrance material. Furthermore the invention relates to flavor and fragrance formulations comprising such a specific organic compound.
Type:
Grant
Filed:
October 7, 2013
Date of Patent:
April 17, 2018
Assignee:
DSM IP ASSETS B.V.
Inventors:
Raphael Beumer, Johannes Tschumi, Michael Gressly
Abstract: The present invention relates to a variant polypeptide having fumarate reductase activity, which has modified NADP(H)-dependent and/or NAD(H)-dependent activity as compared with a reference polypeptide having fumarate reductase activity. Such a variant may be overexpressed in a host cell in order to improve production of a dicarboxylic acid.
Type:
Grant
Filed:
December 12, 2014
Date of Patent:
April 17, 2018
Assignee:
DSM IP ASSETS B.V.
Inventors:
René Marcel De Jong, Zheng Zhao, Ben Den Dulk, Remko Tsjibbe Winter
Abstract: The invention relates to a method for forming a liquid radiation curable resin capable of curing into a solid upon irradiation comprising at least one thermally sensitive visual effect initiator. The liquid radiation curable resin is capable of curing into three-dimensional articles having selective visual effects. The resulting three-dimensional articles possess excellent color and/or transparency stability and excellent mechanical properties.
Type:
Grant
Filed:
January 21, 2011
Date of Patent:
March 27, 2018
Assignee:
DSM IP ASSETS, B.V.
Inventors:
Beth Ficek, John Southwell, Brett Register
Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
Type:
Grant
Filed:
March 22, 2010
Date of Patent:
March 27, 2018
Assignee:
DSM IP Assets B.V.
Inventors:
Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
Abstract: The present invention relates to a powderous formulation comprising powder particles. These powder particles do comprise polyunsaturated oils, especially polyunsaturated fatty acids, and the powder do have at the same time an excellent sensory profile, a fine particle structure and a high oil loading.
Type:
Grant
Filed:
November 28, 2013
Date of Patent:
March 20, 2018
Assignee:
DSM IP ASSETS B.V.
Inventors:
Jimbin Mai, Gang Su, Pablo Oliver Velarde Pena
Abstract: A cover assembly for an electrical connector at the end of a sheathed cable containing several insulated wires. An insulation piercing clip couples light bulb leads to the wires. A translucent housing encloses the light bulb, said insulation piercing clip, the entire section of unsheathed insulated wires, a portion of the electrical connector and a portion of the sheathed cable. The cover assembly is illuminated by the light bulb when power flows through the electrical connector and may be color coded to indicate connector function.
Abstract: The invention relates to an offshore drilling or production vessel comprising a platform and a mooring system attached thereto, said mooring system comprising: i.) a support frame with a winch-drum mounted thereon; ii.) a mooring line for mooring said platform to the ocean floor, said mooring line comprising a first portion and a second portion; wherein said first portion is hauled on and paid off by said winch-drum; wherein said second portion is anchored to the ocean floor; characterized in that the mooring line is a single length mooring line comprising high strength polyolefin fibers; wherein the first portion of the mooring line has a first mass (M1) of polyolefin fibers per unit length and the second portion of the mooring line has a second mass (M2) of polyolefin fibers per unit length; wherein the ratio M1/M2 is greater than 1 and wherein said first portion extends continuously into said second portion through a tapered portion of the mooring line.
Type:
Grant
Filed:
October 9, 2013
Date of Patent:
February 27, 2018
Assignee:
DSM IP ASSETS B.V.
Inventors:
Martin Pieter Vlasblom, Jorn Boesten, Rigobert Bosman
Abstract: Fine pitch electrical connector socket, comprising at least two opposing walls between which a passageway is defined for receiving an insert with contact pins, the walls being formed from a fiber reinforced flame retardant thermoplastic polymer composition comprising a polyamide polymer, a flame retardant system and a fibrous reinforcing agent, wherein the polyamide polymer comprises at least a semi-crystalline polyamide (A) having a melting temperature Tm-A of at least 280° C., and optionally a second polyamide (B); the polyamide polymer has a crystallization enthalpy ?Hc of at least 50 J/g, the melting temperature Tm-A and crystallization enthalpy ?Hc being measured by DSC with the method according to ISO11357-1/3 with a heating and cooling rate of 20° C.; the flame retardant system comprises a combination of (C-1) a metal salt of dialkylphosphinate and/or diphosphinate and (C-2) a metal salt of phosphoric acid; and the composition has a heat distortion temperature of at least 265° C.