Abstract: The present invention relates to the use of a phosphate ester emulsifier for reducing the cloth staining tendency of at least one UV filter substance selected from the group consisting of a triazine derivative, an amino substituted hydroxybenzophenone and/or a benzotriazol derivative. Furthermore, the invention relates to topical compositions comprising a phosphate ester emulsifier and at least one benzotriazol and at least one UV filter substance selected from the group consisting of a triazine derivative and an amino substituted hydroxybenzophenone as well as mixtures thereof.
Abstract: The present invention relates to novel compositions for treating seeds. Moreover, the present invention is directed to the production of these compositions and the uses of these compositions.
Type:
Application
Filed:
December 21, 2012
Publication date:
October 16, 2014
Applicant:
DSM IP ASSETS B.V.
Inventors:
Frederik Jan Hendrik Schreurs, Jacobus Stark, Angelique De Rijk
Abstract: The invention relates to a novel method for the production of ?-carotene from submerged cultures of mucoral fungi such as Blakeslea, Choanephora or Phycomyces by adding lectin to the culture medium and performing pH control once fermentation has started. The method involves ?-carotene recovery stage that makes it possible to simplify the process, optimize yields and increase purification of the product.
Type:
Grant
Filed:
July 18, 2001
Date of Patent:
October 14, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Javier Costa Perez, Antonio Estrella Castro, Ana Teresa Marcos Rodriguez, J. Emiliano Gonzalez De Prado, Enrique R. Peiro Cezon, Alfonso Collados De La Vieja, Manuel Esteban Morales
Abstract: Disclosed are chimeric polyunsaturated fatty acid (PUFA) olyketide synthase (PKS) proteins and chimeric PUFA PKS systems, including chimeric PUFA PKS proteins and systems derived from Schizochytrium and Thraustochytrium. Disclosed are nucleic acids and proteins encoding such chimeric PUFA PKS proteins and systems, genetically modified organisms comprising such chimeric PUFA PKS proteins and systems, and methods of making and using such chimeric PUFA PKS proteins and systems.
Type:
Grant
Filed:
October 2, 2012
Date of Patent:
October 14, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Craig A. Weaver, Ross Zirkle, Daniel H. Doherty, James G. Metz
Abstract: The present invention relates to the use of Listeria bacteriophage endolysins for controlling Listeria contamination of pasta filata cheese and related food products. The present invention also relates to the use of Listeria bacteriophage endolysins for extending the shelf life of pasta filata cheese and related food products. Furthermore, the present invention relates to a food product comprising pasta filata cheese and a Listeria bacteriophage endolysin as well as a method of making such a food product.
Type:
Application
Filed:
May 29, 2012
Publication date:
October 9, 2014
Applicant:
DSM IP ASSETS B.V.
Inventors:
Jacobus Stark, Maartje Maria Franse, William Robert King
Abstract: Partially deamidated rice endosperm protein or rice endosperm protein which is partially conjugated with mono-, di-, oligo- or polysaccharides is used as novel protective hydrocolloid for fat-soluble active ingredients and/or fat-soluble colorants. The present invention further includes compositions comprising that rice endosperm protein and at least one fat-soluble active ingredient/colorant, as well as their manufacture, that rice endosperm protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions. The present invention is directed to theses uses and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a rice endosperm protein and such a composition, respectively.
Type:
Grant
Filed:
March 22, 2008
Date of Patent:
October 7, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Navagnana S. Heittiarachchy, Bruno H. Leueberger, Ilankovan Paraman, Christian Schaefer
Abstract: The invention relates to a process for the isomerization of unsaturated fatty acids or esters or amides thereof, said process comprising reacting: (a) an unsaturated fatty acid or ester or amide thereof; (b) a source of Pd; (c) a bidentate diphosphine of formula I, R1R2>P1-R—P2<R3R4??(I) wherein P1 and P2 represent phosphorus atoms; R1, R2, R3 and R4 represent tert-butyl; and wherein R represents an optionally substituted aromatic group spanning P1 and P2; (d) a lower alcohol; and (e) an acid co-catalyst, under conditions for isomerization to take place. The process is particularly advantageous for the isomerization of substituted alkenes harboring a hydroxy group when the desired end product has a keto group, such as ricinoleic acid or ester thereof.
Type:
Grant
Filed:
July 12, 2012
Date of Patent:
October 7, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Natascha Sereinig, Michèle Catherine Christianne Janssen, Johannes Gerardus De Vries
Abstract: The invention relates to the field of recombinant DNA technology for the production of chondroitin, including the production of chondroitin sulfate via a combination of recombinant bacterial fermentation and post-fermentation sulfation.
Type:
Application
Filed:
February 20, 2014
Publication date:
October 2, 2014
Applicants:
Seikagaku Corporation, DSM IP ASSETS B.V.
Inventors:
Daniel H. DOHERTY, Craig A. WEAVER, Kentaro MIYAMOTO, Toshikazu MINAMISAWA
Abstract: The present invention to stable carotenoid emulsions, which—when used in a liquid formulation (especially a beverage, such as a soft drink)—allows to obtain transparent formulation (even after pasteurization).
Abstract: This invention relates to a method of marketing 25-hydroxyvitamin D3 (25-OH D3) comprising providing an effective dose of 25-OH D3 and informing the potential consumer that it is beneficial for increasing or maintaining executive functioning, or lessening the decrease of cognitive functioning. Kits containing the 25-OH D3 and information regarding its benefits in this area are also part of this invention.
Abstract: This invention relates to a novel process for the synthesis of R-biphenylalaninol and to intermediate compounds that are formed in the process according to the invention, i.e. novel intermediates useful in the synthesis of R-biphenylalaninol. The in vention also relates to R-biphenylalaninol, The process according to the invention, the intermediates to of R-biphenylalaninol and of R-biphenylalaninol are all useful in the synthesis of pharmaceutically active compounds.
Type:
Application
Filed:
August 16, 2012
Publication date:
October 2, 2014
Applicants:
DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG, DSM IP ASSETS B.V.
Inventors:
Petrus Johannes Hermsen, Peter Hans Ermann, Peter Hans Riebel, Michael Wolberg, Andreas Hendrikus Maria De Vries
Abstract: The invention relates to R-hydroxynitrile lyases with improved substrate acceptance, increased activity and increased selectivity, obtainable by introducing random mutations with the aid of random mutagenesis and/or saturation mutagenesis techniques, identifying by means of screening or selection and, where appropriate, subsequently combining advantageous mutations, and to the use thereof.
Type:
Grant
Filed:
December 11, 2007
Date of Patent:
September 30, 2014
Assignee:
DSM IP Assets BV
Inventors:
Richard Gaisberger, Anton Glieder, Zhibin Liu, Beate Pscheidt
Abstract: The invention relates to a surgical repair article, comprising a structural member of high performance polyethylene (HPPE) filament(s). The invention also relates to a method of making such a surgical repair article, and to a kit of parts comprising the article. The surgical repair article comprises a structural member of high performance polyethylene (HPPE) filament(s), and a biodegradable coating applied to the surface of the structural member, wherein the coating comprises a sol/gel produced inorganic oxide and a biologically active compound incorporated therein. The article combines high tensile strength, biocompatibility and favorable bioactive compound delivery characteristics.
Type:
Grant
Filed:
August 5, 2010
Date of Patent:
September 30, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Claudia Maria Vaz, Gerardus Aben, Edith Elisabeth Van Den Bosch
Abstract: Non-fibrous-reinforced thermoplastic moulding compositions comprising a metal powder as a heat stabilizer are provided. The metal powder has a weight average particle size (dm) of at most 1 mm and the metal in the metal powder is selected from the group consisting of elementary metals from Group VB, VIIB, VIIB and VIIIB of the Periodic Table, and mixtures thereof. A thermoplastic polyamide is also provided with an Mw of at most 50,000 g/mol, or a blend of at least two thermoplastic polymers with Tmelt or Tg differing by at least 20° C., or a second thermostabilizer. The invention also relates to the use of these compositions in high temperature applications.
Abstract: The process of the present invention comprises reacting an aldehyde or ketone with an alcohol in the presence of a solid acid, and removing removing water and methanol from the reaction product by pervaporation, characterized in that a membrane having a flux density for water of 0.04 to 2.8 kg/(hm2) is used to remove the water and another membrane having a flux density for methanol of 2.0 to 100 kg/(hm2) is used to remove the methanol.
Abstract: Disclosed are novel acyl-CoA synthetases and novel acyltransferases, nucleic acid molecules encoding the same, recombinant nucleic acid molecules and recombinant host cells comprising such nucleic acid molecules, genetically modified organisms (microorganisms and plants) comprising the same, and methods of making and using the same. Also disclosed are genetically modified organisms (e.g., plants, microorganisms) that have been genetically modified to express a PKS-like system for the production of PUFAs (a PUFA PKS system or PUFA synthase), wherein the organisms have been modified to express an acyl-CoA synthetase, to express an acyl transferase, to delete or inactivate a fatty acid synthase (FAS) expressed by the organism, to reduce competition for malonyl CoA with the PUFA synthase or to increase the level of malonyl CoA in the organism, and in one aspect, to inhibit KASII or KASIII.
Type:
Application
Filed:
March 21, 2013
Publication date:
September 25, 2014
Applicant:
DSM IP Assets B.V.
Inventors:
James G. METZ, Jerry M. Kuner, James Casey Lippmeier
Abstract: Compositions containing a combination of hydroxytyrosol and resveratrol or liqustilide or (?)-epigallocatechin gallate or honokiol or genistein or Magnolia bark extract or a combination of oleuropein and resveratrol or ligustilide are used to treat inflammatory disorders.
Type:
Grant
Filed:
July 12, 2007
Date of Patent:
September 23, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Daniel Raederstorff, Nathalie Richard, Joseph Schwager, Karin Wertz
Abstract: A method to increase the production of a desired chemical compound in a microorganism by introduction of a DNA sequence at the 5? end of the encoding DNA gene sequence capable of forming a stem loop and capable of increasing the stability of mRNA transcripts from one or more genes, thus stabilized mRNAs, corresponding DNA sequences and microorganisms.
Type:
Grant
Filed:
December 1, 2006
Date of Patent:
September 23, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Abel Ferrandez, John B. Perkins, Michèle Schaber
Abstract: A thermostabilized thermoplastic moulding composition includes a) a thermoplastic polyamide composition which consists of a blend of at least two polyamides. The at least two polyamides include a1) at least 50 mass %, relative to the total mass of the thermoplastic polyamide composition, of a first polyamide (PA-1) selected from the group consisting of polyamide-4,6, polyamide-6,6 and semi-aromatic polyamides and mixtures thereof; and a2) an amount of 1-50 mass %, relative to the total mass of the thermoplastic polyamide composition, of a second polyamide (PA-2) selected from the group consisting of polyamide-6 and copolymers thereof. The composition also contains b) 0.001-3 mass %, relative to the total mass of the thermoplastic polyamide composition, of a copper salt; and c) 0.01-10 mass %, relative to the total mass of the thermoplastic polyamide composition, of iron oxide. The moulding composition exhibits reduced deterioration when exposed to an elevated temperature of 230° C.