Patents Assigned to DSM
  • Mixture of peptide-bound tryptophan and polypeptide-bound tryptophan
    Patent number: 8802088
    Abstract: The present invention relates to a composition which comprises tryptophan whereby 10 to 90%, preferably 20 to 80% of the tryptophan is present as free tryptophan or peptide-bound tryptophan and 10 to 90%, preferably 20 to 80% of the tryptophan is present as polypeptide-bound tryptophan.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: August 12, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Cinderalla C. Gerhardt, Luppo Edens
  • Talaromyces transformants
    Patent number: 8802415
    Abstract: The invention relates to a Talaromyces transformant comprising one or more recombinant gene, capable of producing cellulase in the absence of cellulase inducer in a glucose medium, having a cellulase activity of 2 WSU/ml or more, in 16 times or more diluted supernatant or broth.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: August 12, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Alrik Pieter Los, Brenda Vonk, Marco Alexander Van Den Berg, Robbertus Antonius Damveld, Cornelis Maria Jacobus Sagt, Adrianus Wilhelmus Hermanus Vollebregt, Margot Elisabeth Francoise Schooneveld-Bergmans
  • BIODEGRADABLE POLYESTERAMIDE COPOLYMERS FOR DRUG DELIVERY
    Publication number: 20140220099
    Abstract: The present invention relates to a poly (ester amide) (PEA) having a chemical formula described by structural formula (IV), wherein m+p varies from 0.9-0.1 and q varies from 0.1 to 0.9 m+p+q=1 whereby m or p could be 0 n is about 5 to about 300; (pref. 50-200) R1 is independently selected from the group consisting of (C2-C20) alkylene, (C2-C20) alkenylene, —(R9—CO—O—R10—O—CO—R9)—, —CHR11—O—CO—R12—COOCR11— and combinations thereof; R3 and R4 in a single backbone unit m or p, respectively, are independently selected from the group consisting of hydrogen, (C1-C6)alkyl, (C2-C6)alkenyl, (C2-C6)alkynyl, (C6-C10)aryl, (C1-C6)alkyl, —(CH2)SH, —(CH2)2S(CH3), —CH2OH, —CH(OH)CH3, —(CH2)4NH3+, —(CH2)3NHC(?NH2+)NH2, —CH2COOH, —(CH2)COOH, —CH2—CO—NH2, —CH2CH2—CO—NH2, —CH2CH2COOH, CH3—CH2—CH(CH3)—, (CH3)2—CH—CH2—, H2N—(CH2)4—, Ph-CH2—, CH?C—CH2—, HO-p-Ph-CH2—, (CH3)2—CH—, Ph-NH—, NH—(CH2)3—C—, NH—CH?N—CH?C—CH2—.
    Type: Application
    Filed: June 25, 2012
    Publication date: August 7, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Guy Draaisma, George Mihov
  • CRYSTAL FORMS OF ASTAXANTHIN
    Publication number: 20140221694
    Abstract: The invention describes previously undisclosed crystal forms of astaxanthin designated crystal form I and II. It has been surprisingly found that the two crystal forms of astaxanthin show an improved bioavailability, a relatively high solubility in specific organic solvents and an increased long-term stability. For example the new forms are stable in solid form for at least 90 days at a temperature of 20° C.-40° C. It was further found that the two crystal forms can be prepared from each other. Therefore the invention also relates to methods for preparing said crystal forms. In addition, the invention relates to administration forms (hereinafter also called “formulations”) comprising one of the two crystal forms according to the invention or mixtures thereof dissolved or suspended in oil or organic-solvent.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Jingfei GUO, Matthew J. JONES, Christian SCHAEFER, Joachim ULRICH, Viviane VERLHAC-TRICHET
  • SUNSCREENS
    Publication number: 20140219938
    Abstract: The present invention relates to a composition for topical application in the form of an oil-in-water (O/W) emulsion comprising in a physiologically acceptable medium at least a dibenzoylmethane derivative, an amino substituted hydroxybenzophenone derivative and a benzotriazol derivative.
    Type: Application
    Filed: June 6, 2012
    Publication date: August 7, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventor: Christine Mendrok-Edinger
  • COMPOSITION FOR THE REDUCTION OF DRIP LOSSES IN PORK
    Publication number: 20140221324
    Abstract: 25-hydroxyvitamin D3 has been found to reduce drip losses in swine carcasses. Feed containing about 25-75 ?g/kg 25-hydroxyvitamin D3 improves the water holding capacity of meats, including pork.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Arturo PINON-QUINTANA, Carlos SIMOES-NUNES
  • SUNSCREENS
    Publication number: 20140219942
    Abstract: The present invention relates to a composition for topical application comprising at least a benzotriazol derivative and a cosmetic solvent selected from the group consisting of benzoate solvents such as phenethyl benzoate, dimethyl capramide and diethylhexyl 2,6-naphthalate. Furthermore, the invention relates to the use of specific benzotriazol derivatives to mask the off-odor of cosmetic solvents such as particularly phenethyl benzoate, dimethyl capramide and diethylhexyl 2,6-naphthalate.
    Type: Application
    Filed: June 6, 2012
    Publication date: August 7, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventor: Christine MENDROK-EDINGER
  • BI-AXIALLY STRETCHED PRODUCT
    Publication number: 20140221600
    Abstract: This invention relates to a biaxially stretched product comprising a copolyamide comprising monomeric units of: aliphatic non-cyclic diamines X and aliphatic non-cyclic dicarboxylic acids Y or aliphatic non-cyclic ?,?-amino acids Z, and diamines M and diacids N in an amount between 0.1 to 2 wt % based on the total amount of copolyamide, and in which M and N are cyclic, and wherein the product has been stretched at a temperature of between the glass transition temperature (Tg) and the melting temperature (Tm). A method of preparation is claimed, as well as a multilayer film comprising the biaxially stretched product.
    Type: Application
    Filed: June 28, 2012
    Publication date: August 7, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Alexander Antonius Marie Sroeks, Serbia Tomic
  • Primer for coating coiled wires
    Patent number: 8795830
    Abstract: Disclosed is a method to provide a metal wire with a coating system comprising a primer and a topcoat, particularly a hydrophilic, lubricious topcoat. The method comprises applying directly onto the wire metal a primer coating composition, which is an aqueous coating composition comprising a multiphase vinyl polymer, the polymer comprising a first phase having a Tg in the range of from ?20° C. to 40° C. and a hard phase having a Tg in the range of from 25° C. to 120° C. The primer has good adhesion to both the metal surface and the topcoat, and provides the eventual coating system with, inter alia, a good flexibility.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: August 5, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Paul Wyman, de Nik Bont, Hinrike Malda, Mamix Rooijmans, Jurgen Scheerder, Rajasingham Satgurunathan, Thomas L. M. Frijns
  • Compositions of fat-soluble substances
    Patent number: 8795715
    Abstract: The invention relates to novel powderous, water-soluble compositions of fat-soluble substances and aqueous solutions or emulsions thereof, wherein the fat-soluble substance(s) are encapsulated as inner (discontinuous phase) within an outer (continuous) phase of a matrix substance.
    Type: Grant
    Filed: June 21, 2010
    Date of Patent: August 5, 2014
    Assignee: DSM IP Assets B.V.
    Inventor: Elger Funda
  • Solventless Extraction Process
    Publication number: 20140212936
    Abstract: The present invention provides a method for extracting lipids from microorganisms without using organic solvent as an extraction solvent. In particular, the present invention provides a method for extracting lipids from microorganisms by lysing cells and removing water soluble compound and/or materials by washing the lysed cell mixtures with aqueous washing solutions until a substantially non-emulsified lipid is obtained.
    Type: Application
    Filed: April 3, 2014
    Publication date: July 31, 2014
    Applicant: DSM IP Assets B.V.
    Inventors: Craig M. Ruecker, Swithwin Patrick Adu-peasah, Brian S. Engelhardt, George T Veeder, III
  • MARKETING N-METHYLSEROTONIN AND RELATED SUBSTANCES FOR USE IN TREATING/ LESSENING THE OCCURRENCE OF HOT FLASHES RELATED TO MENOPAUSE
    Publication number: 20140213536
    Abstract: Zanthoxylum piperitum (commonly known as Japanese pepper) seeds, including its mature seeds, contain the NMS precursor N-methylserotonin S-O-6-glucoside (“NMS-glucoside”) present in sufficient concentration and are metabolized with sufficient efficiency so as to provide an effective amount of NMS for use in amelioration of menopausal symptoms, including hot flashes/flushes. The Japanese pepper seeds or Japanese pepper seed extracts can also be used to enrich other sources of NMS or NMS precursors in order to provide a nutraceutical or food supplement for controlling hot flashes. This invention relates to the marketing of nutraceuticals and food supplements containing these ingredients. Target customers include perimenopausal women, menopausal women and post menopausal women who wish to reduce the risk of experiencing hot flashes.
    Type: Application
    Filed: January 24, 2014
    Publication date: July 31, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Christopher Michael BUTT, Michael WEISER
  • PREPARATION OF NITRILE COMPOUNDS
    Publication number: 20140213804
    Abstract: The invention relates to novel nitrile compounds according to formula I and II: (I) Formula I wherein: X=—CH3 or —C?N, (II) Formula II wherein: X=—CH3 or —C?N, each Y is independently chosen from —OH or RC(O)O—, each R is independently chosen from a C1?21 alkyl group. The invention also relates to processes for the preparation of nitrile compounds according to formula I and II and to uses of the nitrile compounds.
    Type: Application
    Filed: July 6, 2012
    Publication date: July 31, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Paulus Lambertus Alsters, Edwin Gerard Ijpeij
  • Unsaturated polyester resin
    Patent number: 8790762
    Abstract: The present invention relates to an unsaturated polyester resin comprising itaconate esters as reactive unsaturations, wherein the acid value of the resin is in the range of from 25 to 125 and the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 0.33 to 3. In one embodiment, the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 0.33 to 0.9. In another embodiment, the molar ratio of hydroxyl end groups and carboxylic acid end groups is in the range of from 1.1 to 3.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: July 29, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Marian Henryk Szkudlarek, Johan Franz Gradus Antonius Jansen, Silvana Rensina Antonnietta Di Silvestre, Stefanus Jacobus Duyvestijn
  • Metabolic engineering of xylose-fermenting eukaryotic cells
    Patent number: 8790903
    Abstract: The present invention relates to genetic modifications in eukaryotic host cells that have been transformed to express a xylose isomerase that confers on the host cell the ability to isomerize xylose to xylulose. These genetic modifications are aimed at improving the efficiency of xylose metabolism and include. e.g., reduction of nonspecific aldose reductase activity, increased xylulose kinase activity and increased flux of the pentose phosphate pathway. The modified host cells of the invention are suitable for the production of a wide variety of fermentation products, including ethanol, in fermentation processes in which a source of xylose or a source of xylose and glucose are used as carbon source.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: July 29, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Aaron Adriaan Winkler, Sipko Maarten Kuyper, Wilhelmus Theordorus Antonius Maria De Laat, Johannes Pieter Van Dijken, Jacobus Thomas Pronk
  • Mutant cellobiohydrolase
    Patent number: 8790894
    Abstract: The invention relates to Mutant cellobiohydrolase, being a mutant of SEQ ID NO:1, having a substitution at position N247(I,F,H,W) of SEQ ID NO: 1, wherein the mutant cellobiohydrolase has at least 50% sequence identity with SEQ ID NO: 1, and wherein the mutant cellobiohydrolase has CBHI activity.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: July 29, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Jan Metske Van Der Laan, Margot Elisabeth Francoise Schooneveld-Bergmans, Denise Ilse Jacobs
  • CARBOXYPEPTIDASE FOR CHEESE RIPENING
    Publication number: 20140205717
    Abstract: The present invention relates to a process for the flavour development in a fermented food whereby a carboxypeptidase is used.
    Type: Application
    Filed: February 19, 2014
    Publication date: July 24, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Albertus Alard Van DIJK, Baukje FOLKERTSMA, Petrus Jacobus Theodorus DEKKER
  • PROCESS FOR MAKING A POLYMERIC FILM
    Publication number: 20140205826
    Abstract: The invention relates to a process to make films and tapes from ultrahigh molecular weight polyethylene (UHMWPE) in the solid state. The films and tapes according to the invention have an improved thickness whereby the coefficient of variation of the thickness of the film of at most 6%.
    Type: Application
    Filed: June 29, 2012
    Publication date: July 24, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Reinard Jozef Maria Steeman, Marcel Jongedijk
  • PROCESS FOR 4-METHYLOXAZOLE-5-CARBOXAMIDE
    Publication number: 20140206880
    Abstract: A process for the preparation of 4-methyl-oxazole-5-carboxamide, an intermediate in the synthesis of pyridoxine, by reacting lower alkyl 4-methyl-oxazole-5-carboxy-late with a molar excess of anhydrous, liquid ammonia.
    Type: Application
    Filed: May 31, 2012
    Publication date: July 24, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Werner Bonrath, Jocelyn Fischesser, Hongyan Shen
  • USE OF PROLINE SPECIFIC ENDOPROTEASES TO HYDROLYSE PEPTIDES AND PROTEINS
    Publication number: 20140206036
    Abstract: The present invention relates to a process for the proteolytic hydrolysis of a peptide or a polypeptide, said peptide or polypeptide comprising 4 to 40, preferably 5 to 35, amino acid residues and said peptide or polypeptide is not hydrolysable by subtilisin whereby said peptide or polypeptide is hydrolysed by a proline specific endo protease at a pH of 6.5 or lower, preferably 5.5 or lower and more preferably 5.0 or lower to hydrolyse said peptide or polypeptide.
    Type: Application
    Filed: September 9, 2013
    Publication date: July 24, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Luppo EDENS, Robertus Antonius Mijndert VAN DER HOEVEN, Andre Leonardus DE ROOS, Melissa HARVEY