Abstract: Disclosed is a photocurable resin composition for additive fabrication comprising a polymerizable component that is polymerizable by free-radical polymerization, cat ionic polymerization, or both free-radical polymerization and cationic polymerization, and a photoinitiating system capable of initiating the free-radical polymerization, cationic polymerization, or both free-radical polymerization and cationic polymerization. The photocurable resin composition is a liquid at about 25° C., and is capable of curing to provide a solid upon irradiation with light emitted from a light emitting diode (LED), wherein the light has a wavelength of from about 100 nm to about 900 nm. Also disclosed is a three-dimensional article prepared from the photocurable resin composition for additive fabrication, and a process for preparing three-dimensional articles by additive fabrication.
Abstract: The invention relates to a substrate-based method for forming a three-dimensional object by additive fabrication by coating a liquid radiation curable resin comprising from 30 to 80 wt % of cationically curable compounds on a substrate, contacting the liquid radiation curable resin with a previously cured layer, selectively exposing the layer of liquid radiation curable layer to actinic radiation thereby forming a cured layer, separating the cured layer at the substrate, and repeating the steps a sufficient number of time in order to build up a three-dimensional object.
Abstract: Liquid radiation curable resins for additive fabrication comprising an R-substituted aromatic thioetber triaryl sulfonmm tetrakis(pentafluorophenyl)borate cationic photoinitiator is disclosed. A process for using the liquid radiation curable resins for additive fabrication and three-dimensional articles made from the liquid radiation curable resins for additive fabrication are also disclosed.
Type:
Application
Filed:
December 16, 2010
Publication date:
October 4, 2012
Applicant:
DSM IP ASSETS, B.V.
Inventors:
John Edmund Southwell, Jigeng Xu, Kangtai Ren, Ken Dake, Sam East
Abstract: The present invention provides novel diol compounds, novel cosmetic or dermatological sunscreen compositions containing these compounds and the use of the novel compounds as UV-filters. The compounds are particularly advantageous, because they adhere to the skin and therefore provide sunscreen protection for a prolonged period of time.
Type:
Grant
Filed:
February 28, 2008
Date of Patent:
October 2, 2012
Assignee:
DSM IP Assets B.V.
Inventors:
Jürgen H. Vollhardt, Yevgen Blyumin, Alexander Poschalko
Abstract: The present disclosure pertains to a process for preparing an oxime in which a carbonyl compound is reacted in the liquid phase with NH3 and H2O2 in the presence of a catalyst to form the corresponding oxime, wherein the catalyst comprises a catalytic component selected from the oxides of metals of group 5 and group 6. The use of a niobia catalyst is particularly preferred. The process according to the disclosure is suitable for the manufacture of numerous oximes, in particular cyclohexanone oxime.
Abstract: The present invention provides a method for the preparation of mycophenolate mofetil wherein mycophenolic acid or an amine salt of mycophenolic acid is esterified with 2-morpholinoethanol, the resulting mixture is extracted into water at a pH-value between 1.0 and 3.0, and mycophenolate mofetil is back-extracted in a water-immiscible solvent at a pH-value between 3.0 and 5.0.
Abstract: The present invention relates to a process for recovering succinic acid in crystal form from a fermentation broth comprising succinic acid, comprising the steps of a) bringing the fermentation broth to a pH of between 1 and 4, b) crystallizing the succinic acid from the fermentation broth to form succinic acid crystals, c) dissolving the succinic acid crystals at a temperature of between 30 and 90 degrees Celsius to form an aqueous solution comprising dissolved succinic acid, d) crystallizing the succinic acid from the solution to recover succinic acid in crystal form. The invention further relates to succinic acid in crystal form, comprising a sugar content of 1 to 100 ppm and a nitrogen content of 1 to 80 ppm.
Type:
Application
Filed:
November 19, 2010
Publication date:
September 20, 2012
Applicants:
ROQUETTE FRERES SA, DSM IP ASSETS B.V.
Inventors:
Maarten Job Van De Graaf, Fredoen Vallianpoer, Guillaume Fiey, Loic Delattre, Elisabeth Agnes Michèle Schulten
Abstract: This invention relates to the use of resin compositions for chemical anchoring, wherein the resin composition comprises at least: a. a thiol-containing component, and b. a resin containing one or more reactive moieties selected from the group of: i. non-aromatic carbon double bond moieties, and ii. epoxide moieties, and an initiator. Preferably, the resin composition further comprises a diluent, more preferably a reactive diluent. Furthermore, the present invention also relates to the use of a multi-component, preferably a 2-component system of which one component contains a thiol group(s) containing component for chemical anchoring by means of cold curing.
Type:
Grant
Filed:
October 5, 2006
Date of Patent:
September 18, 2012
Assignee:
DSM IP Assets B.V.
Inventors:
Johan Franz Gradus Antonius Jansen, Michael Alphonsus Cornelis Johannes Van Dijck, Marco Marcus Matheus Driessen
Abstract: The invention relates to a cosmetic or personal care composition comprising a polymer which polymer comprises oxazolidon groups. Examples of cosmetic and personal care compositions include hair spray compositions, mousses, gels, lotions, tonics, shampoos, conditioners, rinses, hand and body lotions, facial moisturizers, sunscreens, anti-acne preparations, topical analgesics, mascara's, eyeliners, blush, liquid lip color, nail polish foundations.
Abstract: The present invention relates to a method for preparing alpha-ketopimelic acid, comprising converting 2-hydroxyheptanedioic acid into alpha-ketopimelic acid, which conversion is catalysed using a biocatalyst. Further, the invention relates to a heterologous cell, comprising a nucleic acid sequence encoding an enzyme having catalytic activity in the conversion of 2-hydroxyheptanedioic acid into alpha-ketopimelic acid. Further, the invention relates to the use of a heterologous cell according to the invention in the preparation of caprolactam, diaminohexane or adipic acid.
Type:
Application
Filed:
September 10, 2010
Publication date:
September 13, 2012
Applicant:
DSM IP ASSETS B.V.
Inventors:
Petronella Catharina Raemakers-Franken, Axel Christoph Trefzer, Linda Vermote
Abstract: Compounds are provided according to structure 1: in which R?H or methyl and R2=optionally substituted C1-C20 alkyl, optionally substituted C6-C20 aryl, part of a oligomeric or polymeric residue (>C20), which can be optionally substituted.
Type:
Application
Filed:
March 13, 2012
Publication date:
September 13, 2012
Applicant:
DSM IP ASSETS B.V.
Inventors:
Joanna KLEIN NAGELVOORT, Cornelis DEN BESTEN, Johan Franz Gradus JANSEN
Abstract: The present invention relates to compositions containing fat-soluble active ingredients and/or colorants in a matrix based on improved modified polysaccharides, i.e. modified polysaccharides where parts were separated, and to a process for preparing these compositions as well as to these improved modified polysaccharides themselves and a process for the manufacture thereof. The present invention further relates to the use of the compositions of this invention for the to enrichment, fortification and/or for the coloration of food, beverages, animal feed, cosmetics and pharmaceutical compositions and to such food, beverages, animal feed, cosmetics and pharmaceutical compositions themselves.
Type:
Application
Filed:
April 23, 2012
Publication date:
September 13, 2012
Applicant:
DSM IP ASSETS B.V.
Inventors:
David SCHAFFNER, Christian SCHÄFER, Bernd SCHLEGEL
Abstract: Solids, including fibers can be easily removed from olive juice by mixing the olive juice with a water-miscible solvent to form two phases and separating the phases. Preferably the solvent is ethanol.
Abstract: The present invention relates to a process for the preparation of octahydrocyclopenta[b]pyrrole-2-carboxylic acid and esters thereof of general formula (1) in the presence of a cobalt and/or nickel comprising catalyst and to the use of compounds of general formula (1) in the synthesis of ramipril.
Abstract: Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity, e.g., lipases, saturases, palmitases and/or stearatases and methods for preparing low saturate or low trans fat oils, such as low saturate or low trans fat animal or vegetable oils, e.g., soy or canola oils.
Type:
Application
Filed:
May 14, 2012
Publication date:
September 6, 2012
Applicant:
DSM IP ASSETS B.V.
Inventors:
Tim HITCHMAN, Christopher L. G. DAYTON, Katie A. KLINE, Jonathan LYON, Mark A. WALL, Nelson R. BARTON
Abstract: The invention relates to a method for the prevention or reduction of haze in a beverage by the addition of a prolyl-specific and/or alamine specific endoprotease and the new beverages obtainable by the method according to the invention. It also relates to new endoproteases. It also relates to methods as described above wherein auxiliary enzymes are used in combination with the specific endoprotease. Sequence information of a genomic DNA, cDNA as well as protein sequences are provided.
Abstract: The present invention relates to a improved process for the biotechnological production of compounds for which ribose-5-phosphate, ribulose-5-phosphate or xylulose-5-phosphate is biosynthetic precursor like riboflavin (vitamin B2), FAD, FMN, pyridoxal phosphate (vitamin B6), guanosine, GMP, adenosine, AMP. The invention further pertains to the generation of the organism producing those compounds. It furthermore relates to the generation of mutated transketolases that allow normal growth on glucose but reduced growth on gluconate when introduced into the production strains and to polynucleotides encoding them.
Type:
Grant
Filed:
October 25, 2006
Date of Patent:
September 4, 2012
Assignee:
DSM IP Assets B.V.
Inventors:
Michael Hans, Dietmar Laudert, Hans-Peter Hohmann, Martin Lehmann
Abstract: The invention relates to a process for the production of a layered composite structure comprising (1) a semi-permeable membrane made of a polymer composition comprising a polyetherester elastomer and (2) at least one web layer bonded to the membrane, wherein the process comprises a step wherein a melt layer of the polymer composition is applied onto the at least one web layer, and wherein the polyetherester elastomer comprises polyether soft segments formed from poly(alkylene-ether)glycols comprising alkylene-ether segments formed from ethylene oxide and polyester hard segments consisting of ester units derivable from short chain diols and dicarboxylic acid consisting of 98-65 mole % terephthalic acid (TPA), 2-35 mole % isophthalic acid (IPA) and optionally 0-20 mole % other dicarboxylic acids, wherein the mole % is relative to the total molar amount of dicarboxylic acid.
Type:
Grant
Filed:
May 30, 2006
Date of Patent:
September 4, 2012
Assignee:
DSM IP Assets B.V.
Inventors:
Hermanus P. Snuverink Ook Lansink, Hendricus F. Aussems, Paul W. J. Heuvel Van Den, Angelika Schmidt
Abstract: Polypeptide and recombinant protein having esterase activity which exhibit the amino acid sequence SEQ. ID. No. 1 and the use thereof.
Type:
Application
Filed:
March 12, 2012
Publication date:
August 30, 2012
Applicant:
DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG
Inventors:
Gerhard Steinbauer, Michael Stanek, Peter Pojarliev, Wolfgang Skranc, Helmut Schwab, Joannes Kierkels, Marcel Wubbolts, Harald Pichler, Manuela Hermann, Christoph Zenzmaier
Abstract: The present invention is directed to a process for the manufacture of compounds of formula IV wherein R1 is an amino protecting group, and R2 is hydrogen or C1-10 alkyl, comprising a) reacting a compound of formula Ia, wherein M+ is a cation, preferably selected from the group consisting of Li+, Na+, K+, ½ Mg2+ and ½ Zn2+, (formula 1a) with an ammonium salt NH4+X?, wherein X? is an anion, preferably selected from the group consisting of chloride, bromide, sulfate and acetate, in a solvent to a compound of formula II b) reacting a compound of formula II with a nitrile R2—CN in the presence of a base to a compound of formula IV. The present invention is further directed to compounds of formula II and their use for the manufacture of vitamin B1.
Type:
Grant
Filed:
July 22, 2009
Date of Patent:
August 28, 2012
Assignee:
DSM IP Assets B.V.
Inventors:
Reinhard Karge, Ulla Letinois, Gerhard Shiefer