Patents Assigned to E
  • Publication number: 20090220949
    Abstract: The present invention is based on the identification of new mutations in KCNQ1 (also termed KvLQTI), KCNH2 (also termed HERG), SCN5A, KCNE1 (also termed minK), KCNE2 (also termed MiRP) genes that encode ionic channels involved in cardiac electrical activity and are potentially responsible for the Long QT Syndrome. According to a main aspect, the invention relates to nucleic acids, oligonucleotides and polynucleotides and mRNA, containing sequences of KCNQ1, KCNH2 SCN5A, KCNE1, KCNE2 genes and cDNAs in a mutated form and to respective variant proteins thereof. A preferred embodiment of the present invention is represented by a diagnostic method based on the identification of a group of about 70 non-private mutations in the KCNQ1, KCNH2 and SCN5A genes, detected at high frequency.
    Type: Application
    Filed: June 7, 2006
    Publication date: September 3, 2009
    Applicants: Fondzione Salvatore Maugeri Clinica Del Lavoro E Della Riabilitazione I.R.C.C.S., Universita' Degli Studi Di Pavia
    Inventor: Silvia Giuliana Priori
  • Publication number: 20090220954
    Abstract: Methods are disclosed for diagnosing increased risk of cardiovascular disease in a subject.
    Type: Application
    Filed: September 20, 2006
    Publication date: September 3, 2009
    Applicants: JOSLIN DIABETES CENTER, INC., ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO OSPEDALE CASA SOLLIEVO DELLA
    Inventors: Alessandro Doria, Vincenzo Trischitta
  • Patent number: 7582403
    Abstract: The invention provides metal compositions, including silver compositions, and thermal imaging donors prepared with the compositions. The donors are useful for thermal transfer patterning of a metal layers and optionally, a corresponding proximate portion of an additional transfer layer onto a thermal imaging receiver. The compositions are useful for dry fabrication of electronic devices. Also provided are patterned multilayer compositions comprising one or more base film(s), and one or more patterned metal layers, including EMI shields and touchpad sensors.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: September 1, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Richard Kevin Bailey, Graciela Beatriz Blanchet, Jonathan V. Caspar, John W. Catron, Reid John Chesterfield, Thomas C. Felder, Feng Gao, Lynda Kaye Johnson, Roupen Leon Keusseyan, Dalen E. Keys, Irina Malajovich, Jeffrey Scott Meth, Geoffrey Nunes, Gerard O'Neil, Rinaldo S. Schiffino, Nancy G. Tassi
  • Patent number: 7582748
    Abstract: The present invention relates to the synthesis of 2?-deoxy-?-L-thymidine, 2?-deoxy-?-L-uridine and 2?-deoxy-?-L-cytidine, and their derivatives, such as the 3?-O-acyl or 3?,5?-O-diacyl prodrugs, including the 3?-O-L-aminoacyl and 3?,5?-O-L-diaminoacyl prodrugs, and particularly the 3?-O-L-valinyl and 3?,5?-O-L-divalinyl prodrugs.
    Type: Grant
    Filed: March 22, 2004
    Date of Patent: September 1, 2009
    Assignee: Microbiologica Quimica E Farmaceutical Ltd.
    Inventor: Jaime A. Rabi
  • Patent number: 7582247
    Abstract: A fiber spinning process which provides an uncharged, electrically conductive polymer-containing liquid stream, issues said liquid stream in combination with a forwarding gas in a direction from at least one spinning nozzle in said spinneret, passes said liquid stream through an ion flow formed by corona discharge to impart electrical charge to the liquid stream, forms fine polymer fibers of said polymer and collects said fine polymer fibers.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: September 1, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Jack Eugene Armantrout, Michael Allen Bryner, Christel Berta Spiers
  • Patent number: 7582240
    Abstract: A thin, uniform membrane comprising polymeric fibrils or a combination of fibrils and particles, wherein the fibrils have randomly convoluted cross-sections, and a process for making the membrane are disclosed. The membrane may be on the surface of a substrate as part of a composite sheet, or as a stand-alone structure.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: September 1, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Robert Anthony Marin, Larry R. Marshall, Amanda Dawn Miller
  • Patent number: 7583427
    Abstract: A sub-assembly for use in forming an electro-optic display comprises (in this order) a light-transmissive substrate (120); discrete areas (204) of electro-optic material separated by gutter areas (205) essentially free from the electro-optic material; and an adhesive layer (122) and/or a release layer (124) peelable from the sub-assembly. A second sub-assembly comprises (in this order) a peelable release sheet (102); discrete areas of electro-optic material (204) separated by gutter areas (205) essentially free from the electro-optic material, and an adhesive layer (206) and/or a peelable release layer (208). Processes for producing these sub-assemblies and for using them to form electro-optic displays are also described.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: September 1, 2009
    Assignee: E Ink Corporation
    Inventors: Guy M. Danner, Valerie C. Northrop, Sandra Rifai, Shamus Ford Patry
  • Patent number: 7582757
    Abstract: There are provided compounds of Ir(III) having ?-diketimine ligands including the complexes having Formula I: L is the same or different at each occurrence and is a cyclometalating bidentate monoanionic ligand coordinated through a nitrogen atom and a carbon atom. R1 and R3 can be the same or different and are independently selected from hydrogen, halogen, alkyl, aryl, alkylaryl and heterocyclic groups. R10 and R11 can be the same or different and are independently selected from hydrogen, halogen, alkyl, aryl, alkylaryl, trialkylsilyl, triarylsilyl, and heterocyclic groups. R2 is hydrogen, alkyl, aryl, alkylaryl, heterocyclic groups, or fluorine. Adjacent R groups can join together to form 5- or 6-membered rings. R8 is H, F, or alkyl. There are also provided electronic devices containing such compounds.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: September 1, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Alexander Z. Bradley, Jeffrey A. Merlo
  • Patent number: 7583251
    Abstract: A dielectrophoretic display comprises a substrate having walls defining at least one cavity, the cavity having a viewing surface and a side wall inclined to the viewing surface; a suspending fluid contained within the cavity; a plurality of at least one type of particle suspended within the suspending fluid; and means for applying to the fluid an electric field effect effective to cause dielectrophoretic movement of the particles to the side wall of the cavity.
    Type: Grant
    Filed: May 1, 2007
    Date of Patent: September 1, 2009
    Assignee: E Ink Corporation
    Inventors: Alexi C. Arango, Joseph M. Jacobson, Karl R. Amundson
  • Patent number: 7584490
    Abstract: A system and method for scheduling advertisements in a television service network environment. An ad scheduler prepares an ad insertion schedule based on channel change statistical information and avail time information. The scheduler evaluates the statistical information, time durations between adjacent avails in a presentation stream, and the relatedness of market segments assigned to a plurality of advertisements. It schedules the ads into presentation stream groups based on this evaluation. The statistical ad scheduling allows the system to eliminate “forced” switching between multiple presentation streams, whereby system wears and malfunctions can be decreased.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: September 1, 2009
    Assignee: Prime Research Alliance E, Inc.
    Inventor: John A. Schlack
  • Publication number: 20090215968
    Abstract: A polyamide resin composition which can improve heat resistance and water absorbency while suppressing the deterioration of processability is provided. Provided is a polyamide resin composition having an aromatic polyamide resin and an epoxy group-containing phenoxy resin having an epoxy group in the molecule of the phenoxy resin, wherein the content of the epoxy group-containing phenoxy resin is 30 to 50% by mass.
    Type: Application
    Filed: May 17, 2006
    Publication date: August 27, 2009
    Applicants: NITTO SHINKO CORPORATION, E. I. DU PONT DE NEMOURS AND COMPANY, DUPONT TEIJIN ADVANCED PAPERS (JAPAN) LIMITED
    Inventors: Yasuyuki Kihara, Yoshiki Takahashi, Hidenori Takayama, Masanori Imai, Yasunori Tanaka, Shinji Naruse, David Wayne Anderson
  • Publication number: 20090215928
    Abstract: A nanofiller masterbatch comprising a nanofiller and an ethylene/ester copolymer having copolymerized units of ethylene and a comonomer selected from monoesters of C4-C8 unsaturated acids having at least two carboxylic acid groups, diesters of C4-C8 unsaturated acids having at least two carboxylic acid groups, and mixtures of two or more thereof; and a nanocomposite comprising a polyolefin and the nanofiller masterbatch are disclosed. Processes for preparing the nanofiller masterbatch and the nanocomposite are also disclosed.
    Type: Application
    Filed: December 11, 2008
    Publication date: August 27, 2009
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: RICHARD T. CHOU, Jingjing Xu
  • Publication number: 20090211251
    Abstract: The invention concerns a mechanism for operating a thermodynamic cycle, particularly a low-temperature power plant, as well as a related process, whereby a low-temperature mass stream (1) feeds a first heat stream to a working fluid (6) circulating in a first cycle at an initial temperature level (T1), whereby subsequent to an expansion of the working fluid in an expansion machine (7) a second heat stream is extracted from the working fluid (6) at a lower expansion temperature level (T5) with respect to the initial temperature level (T1) for an improvement of the energy exploitation of the thermodynamic cycle or the low temperature power plant, which is pumped to a higher pump temperature level and is fed to the low temperature mass stream (1) and/or fed at least partially to the first cycle.
    Type: Application
    Filed: January 22, 2009
    Publication date: August 27, 2009
    Applicant: E-POWER GMBH
    Inventors: Helge B. Petersen, Ingo Schroter
  • Publication number: 20090215951
    Abstract: The disclosure provides a highly loaded pearlescent pigment acrylic polymer slurry concentrate for use as a pearlescent pigment additive for an acrylic polymer sheet, comprising: (a) about 35 to about 45 wt. % of a pearlescent pigment based on the weight of the slurry concentrate; (b) about 1.0 to about 5.0 wt. % of a copolymer dispersant comprising a pigment functional component derived from a monomer selected from the group consisting of urethane or urea, epoxy-containing methacrylate esterified with aromatic carboxylic acids, aliphatic carboxylic acids, ammonia and primary, secondary and tertiary aliphatic amines, primary aromatic amines, and alkyl methacrylate; and a solvent functional component derived from a monomer selected from the group consisting of methyl methacrylate, butyl methacrylate, ethyl hexyl methacrylate, lauryl methacrylate, 1,2-propane diol, 6, hydroxyhexanoic acid, and 2-phenoxyethanol; (c) about 15 to about 45 wt. % of a (C1-C22) alkyl ((C1-C10)alk) acrylate; and (d) about 0.
    Type: Application
    Filed: February 19, 2009
    Publication date: August 27, 2009
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventor: Paul Roger Kust
  • Publication number: 20090215095
    Abstract: The invention provides compositions and methods for measuring human serum hepcidin levels. The invention provides methods for the oxidative refolding of a hepcidin polypeptide to a form that is mature, bioactive and folded as in the native configuration and molecular mass; a method for measuring the level of native, bioactive hepcidin in a vertebrate animal.
    Type: Application
    Filed: November 11, 2008
    Publication date: August 27, 2009
    Applicant: Mark E. Westerman, Ph.D.
    Inventors: Xavier Lauth, Mark E. Westerman, Vaughn E. Ostland, Jason A. Stannard, Michael W. Pennington
  • Patent number: 7579418
    Abstract: The present invention relates to the process of extruding melt drawing fluoropolymer onto conductor to form insulated conductor at a line speed of at least 533 m/min and having no more than 10 sparks and no more than 2 lumps/13.7 km of insulated conductor under conditions that comprise an adequate process window to allow for these results to be obtained at different conditions within the process window. The invention identifies the critical parameters for achieving this process window, namely melt flow rate of the fluoropolymer, preferably being 30±3 g/10 min, and the melt temperature of the extruding/melt-drawing step, preferably being 393° C.±6° C.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: August 25, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Patrick Anthony DeFeo, Glenn W. Heffner, Niall D. McKee, Sundar Kilnagar Venkataraman
  • Patent number: 7579420
    Abstract: A hyperbranched polymer having pendent olefinic groups and comprising polymer units derived from one or more terminally-unsaturated, acyclic aliphatic diene and polymer units derived from maleic anhydride. Optionally, the hyperbranched polymer may further comprise polymer units derived from one or more 1-alkenes and/or a chain transfer agent. A process to prepare the hyperbranched polymer comprises contacting maleic anhydride with at least one terminally unsaturated acyclic aliphatic diene having at least 7 carbon atoms in the presence of an effective amount of a radical initiator in an aprotic solvent under dilute conditions.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: August 25, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Stephen Ernest Jacobson, Patricia Metzger Cotts
  • Patent number: 7578037
    Abstract: The invention relates to a method for fixing a tool (10, 22, 64), especially a shaft tool, in a clamping chuck (8, 18, 60), whereby the tool (10, 22, 64) is introduced into the clamping chuck (8, 18, 60) and fixed therein (8, 18, 60) upon reaching an axial nominal position. According to the invention, the tool (10, 22, 64) is brought against an abutment (42, 70) and the position of a characteristic element of the tool (10, 22, 64) is measured. The tool (10, 22, 64) is positioned in the axial nominal position by moving the abutment (42, 70) along a positioning section (Z1) calculated from the measurement.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: August 25, 2009
    Assignee: E. Zoller GmbH & Co., KG Einstell-und Messgeräte
    Inventor: Christian Pfau
  • Patent number: 7579499
    Abstract: Hexafluoroisobutylene and its higher homologs are easily reacted with SO3 to give fluorosulfates of the formula CH2?C(R)CF2OSO2F, wherein R is a linear branched or cyclic fluoroalkyl group comprised of 1 to 10 carbon atoms and may contain ether oxygen. These compounds react under mild conditions with many nucleophiles to give CH2?C(R)CF2X, where X is derived from the nucleophile. This reaction provides a route to many substituted hexafluoroisobutylenes, which copolymerize easily with other fluoro- and hydrocarbon monomers such as vinylidene fluoride and ethylene.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: August 25, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Victor Filippovich Cherstkov, Nina Ivanova Delyagina, Viacheslav A. Petrov, Paul R. Resnick
  • Patent number: D599324
    Type: Grant
    Filed: August 4, 2007
    Date of Patent: September 1, 2009
    Assignee: E-J Electronics Co., Ltd.
    Inventor: Chun-Liang Shen