Abstract: The invention describes a method and a microscopy system for imaging and analysing stochastically and independently blinking point-like emitters. A multiple-order cumulants analysis in conjunction with an established blinking model enables the extraction of super-resolved environment-related parameter maps, such as molecular state lifetimes, concentration and brightness distributions of the emitter. In addition, such parameter maps can be used to compensate for the non-linear brightness and blinking response of higher-order cumulant images—used for example in Super-resolution Optical Fluctuation Imaging (SOFI)—to generate a balanced image contrast. Structures that otherwise would be masked by brighter regions in the conventional cumulant image become samples using spectral cross-cumulants.

Abstract: Semiconductor device comprising a source electrode, a drain electrode and a semiconducting layer consisting of a single or double 2-dimensional layer(s) made from one of the following materials: MoS2, MoSe2, WS2, WSe2, MoTe2 or WTe2.

Abstract: Integrated receiving circuit for radiofrequency signals an amplifying element using the multiplication zone of a reverse biased semiconductor junction operating in Geiger mode for amplifying an input radiofrequency signal (Vin) and converting it into a digital signal. And a digital part for digitally processing the digital signal.

Abstract: A mechanical teleoperated device for remote manipulation includes a slave unit having a number of slave links interconnected by a plurality of slave joints; an end-effector connected to the slave unit; a master unit having a corresponding number of master links interconnected by a plurality of master joints; and a handle connected to a distal end of the master unit. The device further includes first device arranged to kinematically connect the slave unit with the master unit, second device arranged to kinematically connect the end-effector with the handle, and a mechanical constraint device configured to ensure that one master link of the master unit is guided along its longitudinal axis so that the corresponding slave link of the slave unit always translates along a virtual axis parallel to the longitudinal axis of the guided master link in the vicinity of the remote manipulation when the mechanical teleoperated device is operated.

Abstract: A system and method for in-vivo multi-path analysis and testing of binary software including binary device drivers is disclosed. The system and method may be used to test a binary software system and may comprise a virtual machine, a symbolic execution engine and a modular plugin architecture. In addition, a device driver testing system is also disclosed wherein symbolic execution may be used to explore the device driver's execution paths and check for device driver behavior.

Abstract: A frequency-drift amplification device for a pulsed laser, including: a stretcher for time-stretching an incident laser pulse; at least one amplifying medium for amplifying the laser pulse; a main compressor for time-compressing the laser pulse to a desired duration for an output pulse of the amplification device; and at least one adjustment compressor between the stretcher and the main compressor, and in which the laser pulse undergoes four diffractions on diffraction gratings to time-compress the stretched laser pulse to a duration that is greater than the desired duration for the output pulse of the amplification device.

Abstract: Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged along an supportive backing layer. The microelectrode elements are dimensioned and shaped so as to target individual neurons, groups of neurons, and neural tissue as may be located in an animal nervous system, such as along a region of a cortex of a human brain. Beneficially, the neurological probe can be used to facilitate location of the neurological target and remain implanted for long-term monitoring and/or stimulation.

Abstract: The present invention relates to methods of increasing lifespan, delaying aging, and/or preventing or treating an age-related disease or a mitochondrial disease in a subject, comprising inducing a nuclear-mitochondrial OXPHOS protein dyssynchrony, including inhibiting the mitochondrial translation machinery function, as well as methods for screening agents that are able to increase lifespan, inhibit or delay aging, and/or prevent or treat an age-related disease or disorder, or a mitochondrial disease or disorder, in a subject.

Abstract: In bus communications methods and apparatus, a first set of physical signals representing the information to be conveyed over the bus is provided, and mapped to a codeword of a sparse signaling code, wherein a codeword is representable as a vector of a plurality of components, some of which are quiescent components and some of which are non-quiescent components, wherein the number of quiescent components and non-quiescent components meet a sparseness requirement.

Abstract: A method for determining the geometry and/or the localisation of an object comprising the steps of: sending one or more signals by using one transmitter; receiving by one or more receivers the transmitted signals and the echoes of the transmitted signals as reflected by one or more reflective surfaces building by a computing module a first Euclidean Distance Matrix (EDM) comprising the mutual positions of the receivers; adding to the EDM matrix a new row and a new column, the new row and a new column comprising time of arrivals of said echoes and computing its rank or distance to an EDM matrix determining the geometry and/or the position of the object based on said rank or distance.

Abstract: A method of storing one or more bits of information comprising: forming a magnetic bubble; and storing a said bit of information encoded in a typology of a domain wall of said magnetic bubble. Preferably a bit is encoded using a symmetric topological state of the domain wall and a topological state including at least one winding rotation of a magnetisation vector of the domain wall. Preferably the magnetic bubble is confined in an island of magnetic material, preferably of maximum dimension less than 1 ?m.

Abstract: A method and computing system are proposed for producing an authenticable security device with two sides. The verso side is covered with an adjustable luminescent emissive layer formed by invisible luminescent ink halftones and possibly a UV absorbing printed layer. The recto side is covered with transmissive non-luminescent ink halftones. The backlit colors resulting from the emissions of the luminescent layer or resulting from illumination by normal white light through the transmissive non-luminescent ink halftones are predicted by a backlighting model. This model enables computing the surface coverages of the luminescent and/or non-luminescent ink halftones in order to obtain a desired color either under excitation light (UV light) or under normal white light. This enable creating authenticable backlit images substantially similar to pre-stored reference images, either under normal white light, under excitation light, or under both the normal white light and the excitation light.

Abstract: A method for automatic localization of objects in a mask. The method includes building a dictionary of atoms, wherein each atom models the presence of one object at one location and iteratively determining the atom of said dictionary which is best correlated with said mask, until ending criteria are met. The invention system concerns also automatically detects objects in a mask. At least one fixed camera is provided for acquiring video frames. A computation device is used for calibrating at least one fixed camera for extracting foreground silhouettes in each acquired video frames for discretizing said ground plane into a non-regular grid of potential location points for constructing a dictionary of atoms, and, for finding objects location points with the previous method. And a propagating device is provided to propagate the result in at least one fixed camera view.

Abstract: A Network-On-Chip (NOC) organization comprises a die having a cache area and a core area, a plurality of core tiles arranged in the core area in a plurality of subsets, at least one cache memory bank arranged in the cache area, whereby the at least one cache memory bank is distinct from each of the plurality of core tiles. The NOC organization further comprises an interconnect fabric comprising a request tree to connect to a first cache memory bank of the at least one cache memory bank, each core tile of a first one of the subsets, the first subset corresponding to the first cache memory bank, such that each core tile of the first subset is connected to the first cache memory bank only, and allow guiding data packets from each core tile of the first subset to the first memory bank, and a reply tree to connect the first cache memory bank to each core tile of the first subset, and allow guiding data packets from the first cache memory bank to a core tile of the first subset.

Abstract: A method and passive device for the coherent combination of two amplified and/or spectrally broadened optical beams using at least one bidirectional optical component (A1, A2), the device includes an amplitude division ring interferometer having optical splitting and recombining elements disposed so as to receive an incident optical beam (S0) and to split it spatially into a first secondary input beam (H1) and a second secondary input beam (H2), optical guiding elements disposed so as to define an optical path in the form of a ring in the interferometer, the at least one bidirectional optical component being disposed on the optical path of the ring interferometer, the splitting and recombining elements being disposed in such a way as to receive and to recombine spatially, temporally and coherently the first secondary output beam (H1?) and the second secondary output beam (H2?), so as to form a coherent output beam.

Abstract: A method and a system for increasing the lifespan of a plasma obtained in the atmosphere. The method includes the following steps: emitting a femtosecond laser pulse, referred to as a first pulse, generating a column of plasma by the filamentation phenomenon, and emitting a second YAG laser pulse, focused by way of an axicon on a line in the plasma column, the energy of the photons of the second laser pulse being greater than the attachment energy of the electrons in the plasma to neutral molecules such as oxygen molecules. The duration of the second pulse is greater than the duration of the first pulse, and the delay between the two pulses is greater than one microsecond.

Abstract: An omnidirectional sensor array system, for example a panoptic camera, comprising a plurality of sensors arranged on a support of predetermined shape to acquire data, wherein said sensors are directional and wherein each sensor is attached to a processing node which comprises integrated electronics that carries out at least a portion of the signal processing algorithms locally in order to reduce the computational load of a central hardware unit.

Abstract: The present invention provides methods of increasing muscle mass and muscle mitochondrial oxidative metabolism. Additionally, the invention provides treating various disorders associated with mitochondrial dysfunction, including but not limited to metabolic disorders, muscular dystrophy disorders, neurodegenerative diseases, chronic inflammatory diseases, and diseases of aging.

Abstract: Method for automatic online delineation of an electrocardiogram (ECG) bio signal, said method comprising the detection of said bio signal through several leads followed by the combination of those multiple acquisitions into a single root-mean-squared (RMS) curve, said RMS curve being then undergoing a real-time single-lead delineation based on a mathematical processing.

Abstract: The corrugated component for the transmission and manipulation of electromagnetic signals with frequency up to several THz, comprises an assembly of a plurality of plates stacked together in a hollow guiding rod wherein said plates have at least one aperture of alternating diameter to form a slot or a ridge in alternate fashion, wherein the external shape of said plates corresponds to the internal shape of the hollow guiding rod. The invention also concerns a method for assembling such a corrugated component.