Abstract: Polymorph I of dasatinib monohydrate and Polymorph II of dasatinib, their preparation methods and pharmaceutical compositions containing the same are provided. These polymorphs have better physicochemical properties, are more stable and are more suitable for industrial scale production.

Abstract: The present invention describes a projectile (100,100a,100b,100c,100d) containing two luminescent dye components (123,125) and a dye powder (126). The first luminescent dye component (123) is contained in an ampoule (122) while the second luminescent dye component is contained in a vial (124) disposed inside the ampoule (122). A front crusher (120,120a) is provided at a front of the ampoule to crush into the ampoule and vial, thereby allowing the dye components to react and give a luminous glow. Upon impact at a target, a nose cap (110) of the projectile (100,100a,100b,100c,100d) breaks and a rear crusher (130) behind the ampoule throws the ampoule (122) forward and sputters the luminous dye out of the nose cap (110); at the same time, the dye powder (126) surrounding the ampoule is sputtered out to mark the point of impact. In addition, a thermal glow is also provided to mark the point of impact. Projectiles also allow light tracing.

Abstract: A fluorescence detecting device receives fluorescence emitted by n kinds of measurement objects within wavelength bands FLk (k is an integer of 1 to n) set so that the fluorescence intensity of fluorescence emitted by a measurement object k becomes higher than that of fluorescence emitted by the other one or more measurement objects, and acquires fluorescent signals corresponding to the wavelength bands FLk (k is an integer of 1 to n). Each of the fluorescent signals is subjected to frequency-down conversion by mixing it with a modulation signal for modulating the intensity of a laser beam Lk (k=1) corresponding to at least one of the wavelength bands FLk to produce fluorescence data including the phase delay and intensity amplitude of the fluorescent signal. The fluorescence data is corrected to calculate the phase delay and a fluorescence relaxation time is calculated using the phase delay.

Abstract: A universal microelectromechanical (MEMS) nano-sensor platform having a substrate and conductive layer deposited in a pattern on the surface to make several devices at the same time, a patterned insulation layer, wherein the insulation layer is configured to expose one or more portions of the conductive layer, and one or more functionalization layers deposited on the exposed portions of the conductive layer to make multiple sensing capability on a single MEMS fabricated device. The functionalization layers are adapted to provide one or more transducer sensor classes selected from the group consisting of: radiant, electrochemical, electronic, mechanical, magnetic, and thermal sensors for chemical and physical variables and producing more than one type of sensor for one or more significant parameters that need to be monitored.

Abstract: This invention relates to stabilized aggregates of small primary crystallites of zeolite Y that are clustered into larger secondary particles. At least 80% of the secondary particles may comprise at least 5 primary crystallites. The size of the primary crystallites may be at most about 0.5 micron, or at most about 0.3 micron, and the size of the secondary particles may be at least about 0.8 micron, or at least about 1.0 ?m. The silica to alumina ratio of the resulting stabilized aggregated Y zeolite may be 4:1 or more.

Abstract: A park lock of a transmission, including a park gear; a park pawl rotating about a pawl shaft, the park pawl having a pawl portion locking the park gear, the park pawl including a cam contact portion; a park rod responsive to an operation of a controller, the park rod having a cam portion pressing the cam contact portion to have park pawl engage the park gear; a park sleeve receiving the cam portion and defining a first contact point providing a reactive force to the cam contact portion of the park pawl pressing against the cam portion at a second contact point; a pawl torsional spring biasing the park pawl towards disengagement; and a pawl stopper limiting the rotation of the park pawl wherein motions are constrained within a plane of the transmission and components are rotatingly disposed in parallel axis bores in one half of a transmission case.

Abstract: A method of operating a differential mobility spectrometer includes an ionization chamber, a filter channel and a detection region. In the ionization chamber, analyte ions are produced from a sample, the so-obtained ions are then subjected in the filter channel to a time-varying electric field. The time-varying electric field has a longitudinal field component drawing the analyte ions from the ionization chamber through the filter channel into the detection region and a transversal field component, which is the superposition of an asymmetrically oscillating transversal field causing the analyte ions to move to and fro in transversal direction and a compensation field for selecting a species of analyte ions by substantially canceling the average transversal velocity of the selected species.

Abstract: A multilayer substrate includes a first outer conductive patterned layer, a first insulating layer exposing a portion of the first outer conductive patterned layer to define a first set of pads, a second outer conductive patterned layer, and a second insulating layer exposing a portion of the second outer conductive patterned layer to define a second set of pads. The multilayer substrate further includes inner layers each with an inner conductive patterned layer, multiple inner conductive posts formed adjacent to the inner conductive patterned layer, and an inner dielectric layer, where the inner conductive patterned layer and the inner conductive posts are embedded in the inner dielectric layer, and a top surface of each of the inner conductive posts is exposed from the inner dielectric layer.

Abstract: A method and apparatus for carrying out auto-calibration of one or more piezoelectric elements in a force transducer assembly of a vehicle wheel balancing system. Output electrical signals from the piezoelectric transducers in response to application of a known imbalance force are measured and recorded. Subsequently, during an auto-calibration procedure, a known input signal is selectively applied to at least one piezoelectric element in the force transducer assembly, and at least one output electrical signal is received from the force transducer assembly. The obtained auto-calibration output signals are evaluated with respect to the output signals obtained from a previous auto-calibration, and compensation values are derived there from for application to subsequent output signals obtained during imbalance measurements.

Abstract: The present disclosure provides systems and methods for extending a deterministic network over a wide geographical area. According to one embodiment, an IED may transmit data frames using a deterministic frame-based communication protocol, such as EtherCAT, via a local deterministic fieldbus. A first transceiver may encapsulate the data frames for transmission over a multiplexing synchronized optical network, such as a SONET network. A second transceiver may de-encapsulate the encapsulated data frames and transmit them via a remote deterministic fieldbus, such that communication between the local and remote deterministic fieldbuses is deterministic. Accordingly, an IED may communicate with a high level of determinism and/or in real-time with various components in a power delivery system across a wide geographical area including multiple deterministic fieldbuses.

Abstract: A unified input and display system and method for enabling sensing interferences made by a user (such as touch or hovering) using multiple interference techniques and instruments. One system comprises: a touch screen that enables emitting and guiding light to enable a user to input drawings by physically interfering the light emitted therefrom and displaying of the interference therethrough; a sensing system comprising a multiplicity of optical sensors arranged according to a predefined layout positioned in relation to the touch screen in a manner that allows the sensors to sense light arriving from the touch screen and translate the sensing into frames each including a pixilated image data of the sensed light; and a screen unification module enabling to unify frames sensed by the sensors at a given moment into a single screen reading comprising a unified whole-screen pixilated image data.

Abstract: An apparatus and methods for detecting radiation. A plurality of substantially parallel active collimation vanes are sensitive to the incident radiation for generating at least a first detection signal, and a rear detector detects incident radiation that passes between the substantially parallel active collimation vanes and generates a second detection signal. A processor receives and processes both the first and second detection signals. The active collimator vanes may be enclosed within a light-tight enclosure, and a first photodetector may be provided for detecting scintillation arising at the active collimation vanes, while a second photodetector may be provided for detecting scintillation arising at the rear detector.

Abstract: The present invention provides novel promoter and terminator sequences for use in gene expression in eukaryotic cells, such as algal cells. The invention further provides expression cassettes comprising a promoter, as described herein, operably linked to a gene. The invention further provides expression vectors and host eukaryotic cells, such as algal cells, for expressing a protein encoded by the gene; and methods for stably transforming eukaryotic algae such as Tetraselmis with transgenes.

Abstract: A semiconductor package substrate includes a core portion, an upper circuit layer and a plurality of pillars. The pillars are disposed on and project upward from the upper circuit layer. Top surfaces of the pillars are substantially coplanar. The pillars provide an electrical interconnect to a semiconductor die. Solder joint reliability as between the substrate and the semiconductor die is improved.

Abstract: PROBLEM There is provided a method for producing polylactic acid, which is capable of obtaining polylactic acid at low cost, and having high molecular weight. SOLUTION A method for producing polylactic acid by polymerizing molten lactide using at least one reactor having plug flow characteristics with ?(?), calculated from the following FORMULA (1), of 0.3 or smaller: ?(?)=?0?(E(?)×ABS(1??))d???(1) in the Formula (1), E(?) is a residence time distribution function determined by impulse response by starch syrup having a viscosity of 3 Pa·s, and ? is ratio of elapsed time ? and mean residence time ?0.

Abstract: One embodiment is a gas turbine engine premix injector including a mixing duct, a plurality of air inlet slots leading to the duct, a plurality of gaseous fuel inlet apertures leading to the duct, a plurality of vanes positioned in the duct downstream from said air inlets, a plurality of liquid fuel inlet apertures leading to the duct, and a plurality of discharge windows positioned between the vanes.

Abstract: The disclosed apparatus may include a mounting structure. A first arm may be secured to the mounting structure and extend from the mounting structure. A load cell may be mechanically coupled to the first arm to detect a first load applied to the first arm by relative movement between the first load cell and a viscous material in which the first arm may be submerged or at least partially disposed. A second arm may be secured to the mounting structure and extend from the mounting structure. A second load cell may be mechanically coupled to the second arm to detect a second load applied to the second arm by relative movement between the second load cell and the viscous material. In one embodiment, load data related to the first and second loads may be used to estimate or determine at least one characteristic of the viscous material.

Abstract: A radio frequency (RF) power amplifier with no reference voltage for biasing is disclosed. The RF power amplifier includes a three-terminal current source circuit, a current mirror circuit and an output-stage circuit. The three-terminal current source circuit receives a first system voltage and accordingly outputs a first current and a second current, and a source voltage exists between a first output terminal of the first current and a second output terminal of the second current. The current mirror circuit receives the first current and the second current and accordingly generates a bias current. The output-stage circuit receives the bias current so as to work at an operation point.

Abstract: A test device for testing at least a portion of a virtual electronic control unit with a simulation environment in a simulator, having the virtual electronic control unit and the simulation environment. The virtual electronic control unit has a software component with an external data interface. The simulation environment has a data interface for direct data exchange with the virtual electronic control unit. A test device with reduced adaptation effort is implemented via a virtual electronic control unit pin module that has at least one virtual electronic control unit interface and is connected via the virtual electronic control unit interface to the external data interface of the software component of the virtual electronic control unit.

Abstract: The present invention relates to an apparatus comprising a reactor body to which gas and water are supplied to create a gas hydrate; an upper cover which is engaged to an upper portion of the reactor body, a scraper mounted rotationally within the reactor body, and a motor for providing a driving force to the scraper. It is possible to remove gas hydrate particles attached to at least one of an inner surface of the reactor body and an inner surface of the upper cover, by a rotary driving of the scraper. According to the invention, it is possible to prevent a material hindering a heat transfer by attaching on a wall surface of the reactor, through a process of scraping out gas hydrate particles, when the scraper which is rotationally driven about a center axis of the reactor is close to the inner surface of the reactor.