Patents Assigned to Evolva SA
  • Use of nootkatone to treat mosquito infestations
    Patent number: 11896008
    Abstract: Compositions and methods for treating and preventing mosquito infestations are disclosed herein. Also disclosed herein are compositions and methods to reduce or prevent the spread of diseases for which mosquitoes may act as a vector.
    Type: Grant
    Filed: October 5, 2021
    Date of Patent: February 13, 2024
    Assignee: EVOLVA SA
    Inventors: Jean Amick, Ryan Murphy
  • METHOD FOR PRODUCING PHYTOSPHINGOSINE OR PHYTOCERAMIDE
    Publication number: 20230374559
    Abstract: A method for producing an objective substance, such as phytosphingosine (PHS) and phytoceramide (PHC), comprising a desired alkyl chain using yeast is provided. The objective substance is produced by cultivating yeast having an ability to produce the objective substance in a culture medium containing a fatty acid.
    Type: Application
    Filed: July 12, 2023
    Publication date: November 23, 2023
    Applicants: AJINOMOTO CO., INC., EVOLVA SA
    Inventors: Vsevolod Aleksandrovich Serebrianyi, Olga Aleksandrovna Sofyanovich, Anna Mikhailovna Ozerova, Takashi Kakiyama, Nobuhiro Hiratsuka, Yasuhiro Tateyama, Corina Wirdnam, Sabina de Andrade Pereira TAVARES, Markus Schwab
  • METHOD FOR PRODUCING PHYTOSPHINGOSINE OR PHYTOCERAMIDE
    Publication number: 20230374558
    Abstract: A method for producing an objective substance such as phytosphingosine (PHS) and phytoceramide (PHC) using yeast is provided. The objective substance is produced by cultivating yeast having an ability to produce the objective substance and modified so that the expression and/or activity of a protein(s) encoded by NEM1 and/or SPO7 gene(s) is reduced in a culture medium.
    Type: Application
    Filed: July 12, 2023
    Publication date: November 23, 2023
    Applicants: AJINOMOTO CO., INC., EVOLVA SA
    Inventors: Howard RIEZMAN, Sabina de Andrade Pereira TAVARES, Markus SCHWAB, Vsevolod Aleksandrovich SEREBRIANYI, Olga Aleksandrovna SOFYANOVICH, Anna Mikhailovna OZEROVA, Naoki IWANAGA
  • Production of steviol glycosides in recombinant hosts
    Patent number: 11821015
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: November 21, 2023
    Assignee: Evolva SA
    Inventors: Veronique Douchin, Swee Chuang Lim Hallwyl, Kim Olsson
  • Production of steviol glycoside in recombinant hosts
    Patent number: 11807888
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: November 7, 2023
    Assignee: EVOLVA SA
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Methods of repelling biting arthropods, reducing pathogen spread and treating arthropod infestation
    Patent number: 11800867
    Abstract: The invention relates to biting arthropod repellent compositions comprising nootkatone. The application also relates to a method of repelling said biting arthropods by application of the nootkatone composition to a hard or soft surface, to a method of treating an arthropod infestation and to a method of reducing the transmission of a parasite or disease pathogen spread by a biting arthropod using the nootkatone composition.
    Type: Grant
    Filed: November 12, 2021
    Date of Patent: October 31, 2023
    Assignee: EVOLVA SA
    Inventors: Jean Davin Amick, Bryan N. Julien, Kim Thu Le Greenbaum
  • Use of nootkatone to kill sap-sucking insects
    Patent number: 11737459
    Abstract: Compositions comprising nootkatone and a carrier as well as methods for treating and preventing infestations of sap-sucking insects in plants are disclosed herein.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: August 29, 2023
    Assignee: EVOLVA SA
    Inventors: Jean Davin Amick, Bryan N. Julien, Henrik Meyer
  • Methods for improved production of Rebaudioside D and Rebaudioside M
    Patent number: 11530431
    Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: December 20, 2022
    Assignee: EVOLVA SA
    Inventors: Michael Dalgaard Mikkelsen, Jorgen Hansen, Ernesto Simon, Federico Brianza, Angelika Semmler, Kim Olsson, Simon Carlsen, Louis Düring, Alexei Ouspenski, Paula Hicks
  • Production of steviol glycosides in recombinant hosts
    Patent number: 11466302
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: October 11, 2022
    Assignee: EVOLVA SA
    Inventors: Helene Lunde Robertsen, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • Production of steviol glycosides in recombinant hosts
    Patent number: 11396669
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: July 26, 2022
    Assignee: Evolva SA
    Inventors: Jon Heal, Philipp Berninger, Kim Olsson, Joe Sheridan, Laura Occhipinti, Laura Brembati, Christian Nyffenegger, Christophe Folly
  • Production of mogroside compounds in recombinant hosts
    Patent number: 11248248
    Abstract: The invention relates to recombinant microorganisms and methods for producing mogroside compounds and mogroside precursors.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: February 15, 2022
    Assignee: EVOLVA SA
    Inventor: Jens Houghton-Larsen
  • Production of steviol glycosides in recombinant hosts
    Patent number: 11168343
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: November 9, 2021
    Assignee: EVOLVA SA
    Inventors: Veronique Douchin, Micheael Dalgaard Mikkelsen, Iben Møller-Hansen
  • Method for producing sphingoid base or sphingolipid
    Patent number: 11155841
    Abstract: A method for producing an objective substance such as sphingoid bases and sphingolipids using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance in a culture medium containing an additive that is able to associate with, bind to, solubilize, and/or capture the objective substance, and collecting the objective substance from cells of the yeast and/or the culture medium.
    Type: Grant
    Filed: February 16, 2018
    Date of Patent: October 26, 2021
    Assignees: Ajinomoto Co., Inc., Evolva SA
    Inventors: Markus Schwab, Corina Daniela Wirdnam, Thomas Oestergaard Tange, Maud Babau, Anaelle Hatsch, Fanny Delegrange, David Fischer, Sabina de Andrade Pereira Tavares
  • Recovering and purifying resveratrol produced by microbial fermentation
    Patent number: 11136283
    Abstract: The present invention relates to a process for recovering and purifying resveratrol produced by microbial fermentation. More particularly, the present invention relates to a process for recovering and purifying resveratrol produced by yeast fermentation.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: October 5, 2021
    Assignee: EVOLVA SA
    Inventors: Nicholas Lawrence Ohler, Satish Kumar Bachu, Oliver Frankovic
  • Method for producing phytosphingosine or sphinganine
    Patent number: 11111511
    Abstract: A method for producing an objective substance such as phytosphingosine and sphinganine using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance and modified so that the expression and/or activities of proteins encoded by LCB4 and CKA2 genes are reduced in a culture medium, and collecting the objective substance from cells of the yeast and/or the culture medium.
    Type: Grant
    Filed: February 16, 2018
    Date of Patent: September 7, 2021
    Assignees: AJINOMOTO CO, INC., EVOLVA SA
    Inventors: Markus Schwab, Maud Babau, David Fischer, Anaelle Hatsch, Sabina de Andrade Pereira Tavares, Curt Aime Friis Nielsen, Jens Klein, Corina Daniela Wirdnam
  • Methods and materials for biosynthesis of mogroside compounds
    Patent number: 11091787
    Abstract: Methods for recombinant and enzymatic production of mogroside compounds and compositions containing mogroside compounds are provided by this invention.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: August 17, 2021
    Assignee: EVOLVA SA
    Inventors: Jens Houghton-Larsen, Katarzyna Krzystanek, Angelika Semmler, Iver Klavs Riishede Hansen, Soren Damkiaer, Yaoquan Liu, Jorgen Hansen, Sathish Kumar, Muthuswamy Panchapagesa Murali, Nina Nicoline Rasmussen
  • Production of steviol glycoside in recombinant hosts
    Patent number: 11041183
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: June 22, 2021
    Assignee: EVOLVA SA
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Efficient production of steviol glycosides in recombinant hosts
    Patent number: 11021727
    Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretions of steviol glucosides of interest.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: June 1, 2021
    Assignee: EVOLVA SA
    Inventors: Ernesto Simon, Iben Nordmark Anderson, Michael Dalgaard Mikkelsen, Jorgen Hansen, Veronique Douchin
  • Compositions and methods for the biosynthesis of vanillin or vanillin beta-d-glucoside
    Patent number: 11008592
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: May 18, 2021
    Assignees: INTERNATIONAL FLAVORS & FRAGRANCES INC., EVOLVA SA
    Inventors: Joergen Hansen, Esben Halkjaer Hansen, Honey Polur, Joseph M. Sheridan, Jonathan R. Heal, William D. O. Hamilton
  • Production of steviol glycosides in recombinant hosts
    Patent number: 10982249
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: April 20, 2021
    Assignee: Evolva SA
    Inventors: Veronique Douchin, Swee Chuang Lim Hallwyl, Kim Olsson