Abstract: A method of preparing a specific solid self-nanoemulsifying drug delivery system involves applying an obtained self-nanoemulsifying drug delivery system on a mixture. The mixture contains (ia) 60 to 90 parts by weight of at least one dimethylaminoethyl methacrylate-butyl methacrylate-methyl methacrylate copolymer; (iia) 10 to 40 parts by weight of at least one methacrylic acid-ethyl acrylate copolymer; and (iiia) optionally, at least one additive; where the sum of (a) and (iia) is 100 parts by weight. The solid self-nanoemulsifying drug delivery system obtained by the method of the present invention is useful as a medicament.

Abstract: The invention relates to a method for computer-implemented monitoring of a goods delivery from a seller to a buyer by using an access-restricted DLT system. The DLT system comprises a first DLT node assigned to the buyer and a second DLT node assigned to the seller. In addition, the DLT system provides at least one smart contract with program instructions for entering and checking delivery orders, order confirmations, and outgoing goods logs in the course of goods deliveries from the seller to the buyer, and for validating the goods delivery. The method comprises, for example, initialising the goods delivery in the DLT system, for example, logging the goods delivery in the DLT system and/or, for example, validating the goods delivery in the DLT system.

Abstract: The invention concerns a method for producing a population of particles of a polymer, wherein the polymer is poly-butylene terephthalate (=PBT) or polyethylene terephthalate (=PET) or a copolymer comprising polybutylene terephthalate and/or polyethylene terephthalate, wherein the polymer is dissolved in an organic solvent which solvent is selected such that it completely solubilizes the polymer only at a temperature of the solvent above 100° C., wherein the method comprises heating the solvent and the solid polymer immersed in the solvent at least to a first temperature, at which first temperature the polymer completely dissolves, cooling the solution until a second temperature is reached at which second temperature clouding of the solution starts, further cooling the solution at a rate in a range of 0.05 ° C./min to 5° C./min or keeping the solution at the second temperature or at a temperature up to 3° C.

Abstract: The invention provides a process for preparing sphingolipids, compositions comprising sphingolipids and further components, and for the use of the compositions.

Abstract: The present invention relates to a process for the purification of hydrogen cyanide, comprising the steps of a) splitting a liquid feed stream (1) comprising hydrogen cyanide into at least a first liquid stream (2) and a second liquid stream (3), b) introducing the first liquid stream (2) into a distillation column (4) at a point between the top and the bottom of the distillation column, c) introducing the second liquid stream (3) into the distillation column (4) at the top of the distillation column, d) withdrawing an overhead vapor stream (5) enriched in hydrogen cyanide from the distillation column (4), and e), withdrawing a bottom stream (6) depleted in hydrogen cyanide, wherein the temperature of the second liquid stream (3) in step c) is lower than the temperature of the first liquid stream (2) in step b).

Abstract: A process for the epoxidation of propene involves reacting propene with hydrogen peroxide, in the presence of a methanol solvent and a shaped titanium zeolite epoxidation catalyst in a fixed bed reactor. The process then involves recovering methanol from the reaction mixture, treatment of the recovered methanol by passing it through a bed of an acidic ion exchange resin, and recycling the treated methanol to the epoxidation reaction; as well as regeneration of the acidic ion exchange resin. Catalyst breakage can be reduced or avoided by washing the regenerated bed of an acidic ion exchange resin with methanol until the methanol exiting the resin bed has an apparent pH higher than 1.8, before methanol treated with the acidic ion exchange resin is recycled to the epoxidation reaction.

Abstract: An apparatus and corresponding process can be used for producing nanocarriers and or nanoformulations and corresponding process products. The apparatus is characterized by a vertical orientation of the feed conduits leading to active element. The feed conduits are nested within one another and are axially movable in terms of their orientation to one another. The process provides for the mixing of at least two liquid phases with different acidities. The volume flow of the first phase is greater than that of the second phase.

Abstract: Hydroxy-substituted sphingolipids are useful as constituents in cosmetic formulations. A method for preparing the sphingolipids involves reacting a lysosphingolipid with a hydroxycarboxylic acid or an intramolecular cyclic ester of a hydroxycarboxylic acid. The sphingolipids can be used for therapy or prophylaxis of cell damage, including skin cell damage and cell damage induced by UV radiation.

Abstract: The use of long-chain citric acid esters as additives in aqueous polymer dispersions for production of porous polymer coatings, preferably for production of porous polyurethane coatings, is described.

Abstract: A composition contains n-heptyl-glyceryl ether and at least one further carefully chosen and synergistically active preservative.

Abstract: A polymeric blend contains a polyether block amide and a thermoplastic polymer, where the polyether block amide is based on a subunit 1 and a subunit 2. Subunit 1 is composed of at least one linear aliphatic diamine containing 5 to 15 carbon atoms and at least one linear aliphatic dicarboxylic acid containing 6 to 16 carbon atoms. Subunit 2 is composed of at least one polyether diol containing at least 3 carbon atoms per ether oxygen and primary OH groups at the chain ends. The sum total of the carbon atoms from diamine and dicarboxylic acid is an odd number and is 19 or 21 carbon atoms. The number-average molar mass of the subunit 2 is 200 to 900 g/mol. The thermoplastic polymer is selected from an ethylene/vinylene acetate, a thermoplastic polyester elastomer, a polyolefin elastomer, thermoplastic polyurethane, or any mixture thereof.

Abstract: The invention relates in particular to a process for the preparation of DL/LD-methionine diketopiperazine (I) characterized in that a DD/LL-methionylmethionine-containing aqueous solution or suspension, which has a pH of 3 to 7, measured using a pH electrode at 20° C., is reacted at a temperature of 150 to 220° C., preferably at 170 to 210° C., until an aqueous solution or suspension has formed containing at least a proportion of 30 mol %, preferably 50 mol %, especially 60 mol % of DL/LD-methionine diketopiperazine, based on the total content of DL/LD- and DD/LL-methionine diketopiperazine in the reaction mixture. This process forms part of an overall process for the preparation of DL/LD-methionylmethionine, which is obtained by hydrolysis from the DL/LD-methionine diketopiperazine (I) produced initially.

Abstract: Brushware contains the constituents of monofilaments or bristles, and at least one head, handle, and/or neck. The constituents contain or are made of polymers from the same polymer class selected from among polymers and/or copolymers, and wherein the polymer class is selected from polyamides or polyesters.

Abstract: A composition contains glycolipids and triethyl citrate (TEC). The TEC can assist in stabilizing a foam of a corresponding aqueous composition. A method can be used for preparing a corresponding formulation, preferably a cosmetical or pharmaceutical formulation, by providing the composition and diluting the composition. The pH of the composition may be adjusted during the dilution by adding an organic or inorganic base.

Abstract: A polymer composition can be used for selective absorbing sintering, SAS, or selective inhibition sintering, SIS. The polymer has open mesopores and the cumulative pore volume distribution of the mesopores, measured to DIN 66134, is at least 0.01 cm3/g.

Abstract: The invention provides a process for regenerating a catalyst used for the hydrogenation of an aromatic species, consisting of several steps. First the system is purged with nitrogen, then air is metered in stepwise, and the addition of nitrogen is subsequently ended until only air is present.

Abstract: The invention relates to a method for preparing C—H acidic (meth)acrylates and the uses thereof.

Abstract: The present invention relates to a computer-implemented method for identifying an incorrectly or non-calibrated infrared spectrometer, comprising the steps of a) recording an infrared spectrum of a sample with a first infrared spectrometer to provide a sample infrared spectrum, b) recording an infrared spectrum of the same sample as in step a) with a second infrared spectrometer to provide a reference infrared spectrum, wherein said second spectrometer is a correctly calibrated infrared spectrometer, or b?) providing a reference spectrum of the same sample as in step a), wherein said reference spectrum was recorded on a second infrared spectrometer, which is a correctly calibrated spectrometer, c) determining a difference between the wavelength of each extreme point in the sample of step a) and the wavelength of each extreme point in the reference spectrum of step b) or b?), and d) indicating the infrared spectrometer of step a) as incorrectly calibrated or non-calibrated, when at least one difference was det

Abstract: In a cyclic anthraquinone process for producing hydrogen peroxide, which comprises a distillation unit with vapor compression for concentrating hydrogen peroxide, aqueous condensate from the distillation unit is passed over a bed of a cation exchange resin in its protonated from to provide a purified condensate, and the purified condensate is used as extractant for extracting hydrogen peroxide in the anthraquinone process, as column reflux for the distillation unit or as a diluent for diluting an aqueous hydrogen peroxide solution.

Abstract: A process for removing butenes from C4-hydrocarbon streams containing butanes and butenes involves extractive distillation with a suitable solvent. The process also involves heat integration, which allows utilization of the heat of the solvent for heating and/or at least partly evaporating various streams.