Patents Assigned to Foundation
  • Patent number: 9266937
    Abstract: Disclosed herein are novel proteins that have reduced binding to the interleukin-7 receptor, compositions containing such proteins, and methods of using the same.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: February 23, 2016
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventor: Annette Khaled
  • Patent number: 9267936
    Abstract: A method for forming neuromuscular junctions includes forming functional neuromuscular junctions between motoneurons and muscle cells by co-culturing one or more human motoneurons and one or more human muscle cells in a substantially serum-free medium. A synthetic mammalian neuromuscular junction includes a human motoneuron functionally linked to a human muscle cell in a substantially serum-free medium. An artificial substrate may be used to support the one or more neuromuscular junctions.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: February 23, 2016
    Assignee: University of Central Florida Research Foundation
    Inventors: James Hickman, Xiufang Guo
  • Patent number: 9265410
    Abstract: System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and system reduces and even eliminate many lens artifacts and reflections. By increasing the accuracy, quality, and field of view afforded during clinical examination of the retina, the method and system will allow practitioners to make more accurate diagnoses and will increase safety during retinal surgical procedures.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: February 23, 2016
    Assignee: University of Virginia Patent Foundation
    Inventor: Paul Andrew Yates
  • Patent number: 9269051
    Abstract: In a corpus of scientific articles such as a digital library, documents are connected by citations and one document plays two different roles in the corpus: document itself and a citation of other documents. A Bernoulli Process Topic (BPT) model is provided which models the corpus at two levels: document level and citation level. In the BPT model, each document has two different representations in the latent topic space associated with its roles. Moreover, the multi-level hierarchical structure of the citation network is captured by a generative process involving a Bernoulli process. The distribution parameters of the BPT model are estimated by a variational approximation approach.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: February 23, 2016
    Assignee: The Research Foundation for The State University of New York
    Inventors: Zhen Guo, Mark Zhang
  • Patent number: 9269340
    Abstract: A wireless sensor network for musical instruments is provided that will allow a musician to communicate natural performance gestures (orientation, pressure, tilt, etc) to a computer. User interfaces and computing modules are also provided that enable a user to utilize the data communicated by the wireless sensor network to supplement and/or augment the artistic expression.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: February 23, 2016
    Assignee: University of Florida Research Foundation, Incorporated
    Inventor: Chester James Udell, III
  • Patent number: 9268401
    Abstract: A multidirectional control system with shear feedback, comprising at least one stationary body, a plurality of tactors disposed within the at least one movable body or the at least one stationary body. In some embodiments, a moveable body is included, such that the tactors have at least one degree of freedom of motion with respect to the stationary body or the moveable body within which they are disposed and are operable to engage target areas of a user's skin; and a plurality of actuators capable of moving the tactors.
    Type: Grant
    Filed: October 10, 2011
    Date of Patent: February 23, 2016
    Assignee: University of Utah Research Foundation
    Inventor: William R. Provancher
  • Patent number: 9269127
    Abstract: A hybrid filtering method called Karhunen Loeve Transform-Wavelet (KW) filtering is presented to de-noise dynamic cardiac magnetic resonance images that simultaneously takes advantage of the intrinsic spatial and temporal redundancies of real-time cardiac cine. This filtering technique combines a temporal Karhunen-Loeve transform (KLT) and spatial adaptive wavelet filtering. KW filtering has four steps. The first is applying the KLT along the temporal direction, generating a series of “eigenimages”. The second is applying Marcenko-Pastur (MP) law to identify and discard the noise-only eigenimages. The third applying a 2-D spatial wavelet filter with adaptive threshold to each eigenimage to define the wavelet filter strength for each of the eigenimages based on the noise variance and standard deviation of the signal. Lastly, the inverse KLT is applied to the filtered eigenimages to generate a new series of cine images with reduced image noise.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: February 23, 2016
    Assignee: Ohio State Innovation Foundation
    Inventors: Yu Ding, Prashanth Palaniappan, Orlando P. Simonetti
  • Patent number: 9265735
    Abstract: Methods for treating Alzheimer's Disease (AD) using modulators of lysosomal activity are described herein. More particularly, methods described herein relate to the use and application of compounds or agents that enhance lysosomal activity for the treatment of AD. In a particular aspect, the method relates to the use and application of compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD. Also described herein are methods and assays for screening to identify compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: February 23, 2016
    Assignees: New York University, The Research Foundation for Mental Hygiene, Inc.
    Inventors: Ralph A. Nixon, Ju-Hyun Lee, Devin Wolfe
  • Patent number: 9265818
    Abstract: The present invention relates to methods for stable transfection of Babesia parasites, and for vaccines conferring immunity against parasitic arthropods.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: February 23, 2016
    Assignees: The United States of America, as represented by the Secretary of Agriculture, Washington State University Research Foundation
    Inventors: Carlos E. Suarez, Donald P. Knowles, Jr., Terry F. McElwain
  • Patent number: 9267893
    Abstract: Methods of obtaining a multidimensional image of a sample are provided comprising (a) directing a first coherent light pulse having a first frequency ?1 and a first wave vector k1 at a first location in the sample, (b) directing a second coherent light pulse having a second frequency ?2 and a second wave vector k2 at the first location, (c) directing a third coherent light pulse having a third frequency ?3 and a third wave vector k3 at the first location and (d) detecting a coherent output signal having a fourth frequency ?4 and a fourth wave vector k4. At least two, but optionally all three, of the coherent light pulses each excite a different transition to a discrete quantum state (e.g., transitions to vibrational states or to electronic states) of a molecule or molecular functionality in the sample. Steps (a)-(d) are repeated at a sufficient number of other locations in the sample to provide the multidimensional image.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: February 23, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: John Curtis Wright, Erin Selene Boyle
  • Patent number: 9266172
    Abstract: Embodiments disclosed herein relate to a method for synthesizing self-assembling nanoparticles with defined plasmon resonances. More particularly, certain embodiments disclosed herein relate to an improved method for synthesizing self-assembling gold/gold sulfide nanoparticles by dialyzing samples during the self-assembly process.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: February 23, 2016
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Andre M. Gobin, Dhruvinkumar Patel, Kurtis T. James, Guandong Zhang
  • Patent number: 9270198
    Abstract: A three-phase alternating current (AC) to direct current (DC) converter may include a three-phase AC filter receiving a three-phase AC power supply, a plurality of three-phase current source rectifiers (CSR) connected in parallel with each other and connected to a three-phase AC filter, and an output filter connected to the CSR's to generate a DC output. Each of the CSRs may include six switches and a free-wheeling diode. Each of the three filtered AC inputs from the three-phase AC filter may be connected via a switch of the six switches to selectably send current into a positive line, and each of three filtered AC inputs from the three-phase AC filter may be connected via another switch of the six switches to selectably receive current from a negative line. The free-wheeling diode may have a cathode connected to the positive line and an anode connected to the negative line.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: February 23, 2016
    Assignee: University of Tennessee Research Foundation
    Inventors: Leon Monroe Tolbert, Ben Guo, Fan Xu, Fei Wang, Benjamin J. Blalock
  • Patent number: 9265524
    Abstract: One aspect of the present disclosure relates to a cannula for passing a tissue graft through soft tissue. The cannula can comprise an elongated body including oppositely disposed first and second ends and an axis that extends between the first and second ends. The elongated body can further include a passage extending between the first and second ends. The second end can include a curved portion that terminates at a sharpened, pointed tip configured to pierce and/or cut soft tissue at the surgical repair site. The tip can be axially offset from the axis of the elongated body at an angle that is less than 180°.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: February 23, 2016
    Assignee: The Cleveland Clinic Foundation
    Inventors: Kathleen A. Derwin, Joseph P. Iannotti, Ryan A. Milks
  • Patent number: 9267002
    Abstract: A method of making a hyperbranched amphiphilic polyester compound includes drying under vacuum a mixture of 2-(4-hydroxybutyl)-malonic acid and p-toluene sulphonic acid as catalyst. The vacuum is then released with a dry inert gas after drying. The dried mixture is heated under the inert gas at a temperature sufficient for polymerization. The inert gas is evacuated while continuing to heat the mixture. The formed polymer is then dissolved in dimethylformamide and precipitated out by adding methanol. Modifications of the method yield nanoparticles of polyesters having properties suited for coencapsulating fluorescent dyes together with therapeutic drugs, resulting in theranostic nanoparticles, that is, nanoparticles useful in both therapeutic treatments and diagnostic methods.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: February 23, 2016
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: J. Manuel Perez, Santimukul Santra
  • Publication number: 20160049539
    Abstract: A method of forming a spectral selective coating is disclosed. The method may include providing particles on a substrate, wherein the particles include submicron particles. The method may farther include sintering the particles under atmospheric pressure to form a sintered layer an the substrate and texturing the sintered layer to provide a submicron surface roughness height on the sintered layer.
    Type: Application
    Filed: August 11, 2015
    Publication date: February 18, 2016
    Applicant: University of Virginia Patent Foundation
    Inventors: Mool GUPTA, Ankit SHAH
  • Publication number: 20160047682
    Abstract: An Automatic Pulse Tracer Velocimeter (APTV) including arc-type APTVs and cross-type APTVs along with a field station and a master station capable of wireless communication with a remote computing devices. The APTV measures flow velocity in a flowable medium by injecting a small amount of a conductive tracer solution into a water column. Following injection, a plurality of wire detector pairs positioned downstream of the injection point are programmed to continuously make conductivity measurements at pre-determined time intervals. A tracer curve of the conductivity measurements over time is created and used to obtain velocity measurements.
    Type: Application
    Filed: August 18, 2015
    Publication date: February 18, 2016
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: A. James Crawford, Ni-Bin Chang
  • Publication number: 20160048733
    Abstract: A method for detecting lanes on the road is disclosed. The method including: a phase that generates at least one spatiotemporal image by storing along the time axis at least one line image that contains pixels corresponding to at least one horizontal line established in a road video; a phase that detects, in lane patterns contained in each of the at least one spatiotemporal image, two or more lane points that correspond to the present moment; and a phase that detects lanes by tracing the two or more lane points over time in each of the at least one spatiotemporal image.
    Type: Application
    Filed: August 12, 2015
    Publication date: February 18, 2016
    Applicant: Korea University Research and Business Foundation
    Inventors: Soonhong Jung, Junsic Youn
  • Publication number: 20160046924
    Abstract: An intermediate composite capable of transferring a biological or chemical material to be patterned on a surface. The intermediate composite includes a hydrogel, and particles suspended in the hydrogel, generating a particle-gel composite (composite), the composite is configured to absorb a biological or chemical material (agent), and further configured to deposit the agent when the composite is positioned proximate to a surface on which the agent is to be deposited.
    Type: Application
    Filed: August 12, 2015
    Publication date: February 18, 2016
    Applicant: Purdue Research Foundation
    Inventors: Cagri A. Savran, Bin-Da Chan, Richard Lee Gieseck, III
  • Publication number: 20160046952
    Abstract: Provided herein are constructs for genome editing or genetic engineering in fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.
    Type: Application
    Filed: August 14, 2015
    Publication date: February 18, 2016
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Christopher Todd Hittinger, William Gerald Alexander
  • Publication number: 20160046955
    Abstract: The invention relates to nucleic acids encoding a p-coumaroyl-CoA:monolignol transferase and to inhibitory nucleic acids adapted to inhibit the expression and/or translation of a p-coumaroyl-CoA:monolignol transferase RNA. Inhibition of p-coumaroyl-CoA:monolignol transferase in plants improves the incorporation of monolignol ferulates into the lignin of plants, giving rise to plant biomass that is more easily processed into useful products such as paper and biofuels.
    Type: Application
    Filed: December 14, 2012
    Publication date: February 18, 2016
    Applicants: Board of Trustees of Michigan State University, Wisconsin Alumni Research Foundation, The Board of Trustees of Illinois State University
    Inventors: Curtis Wilkerson, John Ralph, Saunia Withers, John Sedbrook