Patents Assigned to Foundation
  • Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof
    Patent number: 9023348
    Abstract: A composition-of-matter comprising an antibody or antibody fragment including an antigen-binding region capable of specifically binding an antigen-presenting portion of a complex composed of a human antigen-presenting molecule and an antigen derived from a pathogen is disclosed.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: May 5, 2015
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Yoram Reiter, Cyril Cohen
  • Recombinant pokeweed antiviral proteins, compositions and methods related thereto
    Patent number: 9023596
    Abstract: The present invention provides novel, modified pokeweed antiviral proteins, nucleic acids that encode the proteins, conjugates that incorporate the proteins, and methods to make and use the proteins. The present invention also provides methods to administer the conjugates to animals, for the purpose of directing toxin to particular cells.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: May 5, 2015
    Assignees: Colorado State University Research Foundation, Cedus, Inc.
    Inventors: Eric R. Weber, Torrance M. Nett
  • Electric bus and electric bus battery exchange system
    Patent number: 9026357
    Abstract: Provided is an electric bus and an electric bus battery exchange system. The electric bus according to the present invention includes: a battery exchange hole disposed on top of the electric bus for exchanging a discharged battery for a charged battery; a front camera unit taking front images in the process of entering the battery exchange station for battery exchange; a communication unit for receiving position information of the battery exchange unit from the battery exchange station; a route output unit outputting a predicted driving route for reaching a swapping point below the battery exchange unit based on the front images taken by the front camera unit and the position information of the battery exchange unit; and a display unit displaying the predicted driving route outputted by the route output unit, superimposed on the front images taken by the front camera unit.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: May 5, 2015
    Assignees: Kookmin University Industry Academy Cooperation Foundation, Industry-University Cooperation Foundation of Korea Aerospace University
    Inventors: Jun Seok Park, Won-Kyu Kim, Won-Jae Jung
  • Recombinant baculovirus vaccine
    Patent number: 9023365
    Abstract: A recombinant transfer vector capable of expressing a foreign gene fused to a viral gene under the control of dual promoters and a recombinant baculovirus, and methods for production thereof, as well as pharmaceuticals comprising the recombinant baculovirus as an active ingredient.
    Type: Grant
    Filed: February 8, 2007
    Date of Patent: May 5, 2015
    Assignees: Educational Foundation Jichi Medical University, Otsuka Pharmaceutical Co., Ltd.
    Inventors: Shigeto Yoshida, Yoshio Ohba, Norimitsu Hariguchi, Masami Mizukoshi, Masanori Kawasaki, Makoto Matsumoto, Yoshihiro Goto
  • Process for preparing tolvaptan intermediates
    Patent number: 9024015
    Abstract: The present invention provides a novel process for the preparation of 7-chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-one. The present invention also provides an improved process for the preparation of 7-chloro-1-(2-methyl-4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine. The present invention further provides an improved process for the preparation of 7-chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine.
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: May 5, 2015
    Assignee: Hetero Research Foundation
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Dasari Muralidhara Reddy, Maruthi Janakiram Reddy, Bandi Vamsi Krishna
  • In-pipe inspection robot
    Patent number: 9021900
    Abstract: Provided is an in-pipe inspection robot which moves along a path in a pipe to inspect suspected areas such as cracks in the pipe. An in-pipe inspection robot in accordance with an exemplary embodiment of the present invention has a configuration in which two or more operating units having a plurality of arms, which move forward and backward in a radial direction of a pipe, are connected to each other to move in a straight direction or to be bent relative to each other by means of a flexible link mechanism.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: May 5, 2015
    Assignee: Industry-Academic Cooperation Foundation Yonsei University
    Inventors: Hyun Seok Yang, Woong Sun Jeon
  • Insulated herpesvirus-derived gene expression cassettes for sustained and regulatable gene expression
    Patent number: 9023617
    Abstract: Disclosed are genetic expression cassettes, and vector comprising them useful for the delivery of nucleic acid segments encoding selected therapeutic constructs (including for example, peptides, polypeptides, ribozymes, and catalytic RN molecules), to selected cells and tissues of vertebrate animals. The disclosed genetic constructs are useful in the development of gene therapy vectors, including for example, viral vectors such as HSV, retroviral, lentiviral, AV, and rAAV vectors. The expression cassettes disclosed herein provide new tools in the field of gene therapy, and for the treatment of mammalian, and in particular, human diseases, disorders, and dysfunctions. The disclosed compositions may be utilized in a variety of investigative, diagnostic and therapeutic regimens, including the prevention and treatment of a variety of human diseases.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: May 5, 2015
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: David C. Bloom, Antonio L. Amelio
  • Liquid crystal display
    Patent number: 9025120
    Abstract: A liquid crystal display is provided, which includes a first substrate, a plurality of pixels, a second substrate, a plurality of floating electrodes, and a liquid crystal layer. The pixels are arranged in an array on the first substrate, and each of the pixels includes a first electrode and a second electrode, wherein a space is maintained between the first electrode and the second electrode. The floating electrodes are disposed on the second substrate and above the spaces. The liquid crystal layer is located between the first substrate and the second substrate, wherein the liquid crystal layer is optically isotropic when the first electrode and the second electrode have no voltage difference; and the liquid crystal layer is optically anisotropic when the first electrode and the second electrode have a voltage difference therebetween.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: May 5, 2015
    Assignees: Industrial Technology Research Institute, University of Central Florida Research Foundation, Inc.
    Inventors: Yi-Fan Liu, Yu-Cheng Lai
  • Method of detecting the presence of pneumococcal neuraminidases in -infected samples
    Patent number: 9023599
    Abstract: A method of providing protection against pneumococcal infection in a subject is disclosed. The method includes steps of administering to the subject a composition that includes combination of three recombinant pneumococcal neuraminidases: NanA, NanB, and NanC of S. pneumoniae strains CGSP14, wherein administration of the recombinant pneumococcal neuraminidases elicits an immune response to S. pneumoniae, and treats the subject. In one embodiment, the method further includes a step of adding adjuvants to enhance the immune response. The method also includes a step of using passive antibodies, wherein said passive antibodies are anti-neuraminidase antibodies generated from neuraminidases-immunized humanized animals: NanA, NanB, and NanC. Meanwhile, this invention also provides a method for the molecular diagnosis of pneumococcal infection.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: May 5, 2015
    Assignee: Chang Gung Medical Foundation, Linkou Branch
    Inventors: Cheng-Hsun Chiu, Rajendra Prasad Janapatla, Chyi-Liang Chen, Mei-Hua Hsu, Hsiu-Ling Chen, Chung-Tsui Huang, Hsin-Ju Chang, Wan-Ting Liao
  • Cell-permeable peptide
    Patent number: 9023987
    Abstract: The present invention relates to a novel human-derived cell permeable peptide-bioactive peptide conjugate and the use thereof. According to the present invention, cationic cell permeable peptides derived from human bone morphogenetic protein-4 have no toxicity and immunogenicity and thus exhibit high stability as compared to viral peptide delivery vehicles, and can transport cell impermeable material into cells and into an organism without any damage to cell or material, thereby significantly increasing target gene expression. In addition, the peptide may be applied to clinical use without having to undergo a large number of processes and mass-produced, such that the present invention may be useful in the development of a drug delivery system and treatment technologies using said peptide.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: May 5, 2015
    Assignees: Seoul National University R&DB Foundation, Nano Intelligent Biomedical Engineering Corporation Co., Ltd.
    Inventors: Chong-Pyoung Chung, Yoon-Jeong Park, Jue-Yeon Lee, Jin Sook Suh
  • Macrocyclic compounds and methods of treatment
    Patent number: 9023875
    Abstract: The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: May 5, 2015
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Hendrik Luesch, Taori Kanchan, Valerie J. Paul
  • Method of modeling cloud point of a mixture of fatty acid methyl esters using a modified UNIFAC model and a system therefor
    Patent number: 9026421
    Abstract: A method for predicting onset of liquid phase to solid phase transition of a mixture including a plurality of fatty acid methyl esters components. The method includes identifying chemical and molecular structure of each component of the mixture, calculating activity coefficients for each component in a liquid phase and a solid phase, calculating chemical potential for each component in the liquid phase and in the solid phase at a predetermined temperature and a predetermined pressure, and calculating the cloud point of the mixture. A system for carrying out the method is also disclosed.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: May 5, 2015
    Assignee: Purdue Research Foundation
    Inventors: Bernard Y Tao, Junli Liu
  • FGF having enhanced stability
    Patent number: 9023644
    Abstract: Methods are provided that exploit thermostable FGF-1 proteins for support of human pluripotent stem cell cultures. Also provided are compositions containing thermostable FGF-1 for culturing of human pluripotent stem cells.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: May 5, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Guokai Chen, James A. Thomson
  • Horizontal electric field-type liquid crystal display device and method of fabricating the same
    Patent number: 9025110
    Abstract: A horizontal electric field-type liquid crystal display (LCD) device is provided. The LCD device includes first and second substrates disposed opposite and apart from each other, a first electrode formed on an inner surface of the first substrate, a second electrode corresponding to the first electrode and configured to generate an electric field, and a liquid crystal (LC) layer formed between the first and second substrates, the LC layer including a polymer network and LC molecules confined in multiple domains by the polymer network.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: May 5, 2015
    Assignees: LG Display Co., Ltd., Pusan National University Industry-University Cooperation Foundation
    Inventors: Sung-Il Park, Sung-Gu Kang, Yu-Ri Shim, Sun-Yong Lee, Tae-Hoon Yoon, Byung-Wok Park, Byeong-Hun Yu, Dong-Han Song, Sun-Wook Choi
  • Therapeutic compounds
    Patent number: 9024071
    Abstract: The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating 5-HT2C and/or RSK disorders, including diseases and disorders mediated by GPCRs and/or RSKs.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: May 5, 2015
    Assignee: University of Florida Research Foundation, Inc.
    Inventor: Raymond G. Booth
  • White-emitting monomolecular compound using excited-state intramolecular proton transfer, organic electroluminescent element and laser device using the same
    Patent number: 9024036
    Abstract: Provided are a white-emitting monomolecular compound using excited-state intramolecular proton transfer (ESIPT) characteristics, and an organic electroluminescence device and a laser device comprising same. The white-emitting monomolecular compound according to the present invention is prepared by covalently bonding at least two types of molecules which produce different colors and have excited-state intramolecular proton transfer (ESIPT) characteristics. The white-emitting monomolecular compound according to the present invention achieves white luminescence irrespective of the concentration thereof and of the state of the materials thereof, and therefore can be used in a variety of fields including an organic electroluminescence device and a laser device.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: May 5, 2015
    Assignees: Dongwoo Fine-Chem Co. Ltd., SNU R&DB Foundation
    Inventors: Soo Young Park, Sang Hyuk Park, Ji Eon Kwon
  • EXTREME PCR
    Publication number: 20150118715
    Abstract: Methods, devices, and kits are provided for performing PCR in <20 seconds cycle, with improved efficiency and yield.
    Type: Application
    Filed: May 23, 2013
    Publication date: April 30, 2015
    Applicant: University of Utah Research Foundation
    Inventors: Carl T. Wittwer, Steven Jared Farrar
  • GENE IMPLICATED IN DROUGHT STRESS TOLERANCE AND TRANSFORMED PLANTS WITH THE SAME
    Publication number: 20150121570
    Abstract: The present invention relates to a composition for improving a tolerance to drought and oxidative stress of a plant, a plant transformed with the composition, a method for preparing a plant transformed with the composition, a method for improving a tolerance to a drought and oxidative stress and a composition and method for a germination rate of a plant. The nucleotide sequences of the present invention are involved in the drought and oxidative stress-tolerance and germination capacity, therefore may be effectively used for cultivating the plants with enhanced tolerance against abiotic stress or novel function of rapid growing or bolting.
    Type: Application
    Filed: April 22, 2014
    Publication date: April 30, 2015
    Applicant: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Woo Taek KIM, Eun Yu KIM, Moon Yong RYU, Yoon A CHOI
  • Grass ‘Tift 10’
    Patent number: PP25515
    Abstract: The new variety Pennisetum ‘Tift 10’ is provided. The new and distinct variety has high ornamental value, cold tolerance for short periods of time, and disease resistance. The asexually reproduced variety is reliably propagated vegetatively.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: May 5, 2015
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Wayne W. Hanna, S. Kristine Braman, Brian M. Schwartz
  • Grass ‘Tift 15’
    Patent number: PP25517
    Abstract: The new variety Pennisetum ‘Tift 15’ is provided. The new and distinct variety has high ornamental value, cold tolerance for short periods of time, and disease resistance. The asexually reproduced variety is reliably propagated vegetatively.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: May 5, 2015
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Wayne W. Hanna, S. Kristine Braman, Brian M. Schwartz