Abstract: Devices and methods for ligating structures where the loop of the ligation element can be temporarily pre-tightened without locking the loop. This pre-tightening without locking allows the loop of the ligation element to be loosened and repositioned, if necessary, before locking the loop around the anatomical structure.
Type:
Grant
Filed:
October 20, 2009
Date of Patent:
February 24, 2015
Assignees:
Mayo Foundation for Medical Education and Research, Aegis Medical Innovations Inc.
Inventors:
Paul A. Friedman, Charles J. Bruce, Samuel J. Asirvatham, Trevor A. McCaw, Elliot Y. K. Hong
Abstract: This document provides methods and materials for treating cardiovascular tissue. For example, stem cells, compositions containing stem cells, methods for obtaining stem cells, compositions for generating stem cells expressing particular markers, and methods for repairing cardiovascular tissue are provided.
Type:
Grant
Filed:
March 28, 2012
Date of Patent:
February 24, 2015
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: Integrated surgical systems and methods for using same are provided that can receive scanned images and produce a three dimensional model from the images. Based at least in pan on the three dimensional model, a processor generates code defining an optimized tool path, which is sent to a surgical machining system that can machine the desired portion of the patient. In one exemplary aspect, the integrated system operates in a clearly defined and pre-programmed manner with no necessity for in-situ sensory or guidance feedback.
Type:
Grant
Filed:
November 3, 2008
Date of Patent:
February 24, 2015
Assignee:
University of Utah Research Foundation
Inventors:
Alagar K. Balaji, William T. Couldwell, Joel D. MacDonald, Bradley C. Hansen, Aniruddha Lapalikar, Bharat Thakkar, Brenda Marie Thomas
Abstract: A system, a composition, a method and a kit for identifying anti-bacterial agents are provided. The invention described herein is useful in identifying inhibitors of any bacterial stress response. Moreover, the invention can be applied to any sRNA and its target, any transcription factor and its target, and any transcription factor/sRNA pair (i.e., a transcription factor that regulates a sRNA). In particular, the present invention provides a system, a composition, a method and a kit for the identification of cyclic peptides that block the ?E pathway in Escherichia coli.
Type:
Grant
Filed:
December 16, 2011
Date of Patent:
February 24, 2015
Assignee:
The Penn State Research Foundation
Inventors:
Sarah Ellen Ades, Kenneth Charles Keiler
Abstract: A system and method are described for capturing and analyzing gamma rays from neutron excitation of a region in 3-space being analyzed for explosives. A processor analyzes the results, determining whether underground explosives are present in a particular region of the ground. In one embodiment, one gamma ray energy band is used to infer an amount of silicon in the region, while another indicates the combined amount of silicon and nitrogen. The concentration of nitrogen in the region is inferred and used to trigger an “explosive found” or a “no explosive found” signal. In other embodiments, the system or method uses inferences about other elemental constituents of the ground being examined, sometimes taking as input analyzes from prior scans, and providing output indicating the likelihood of the presence of explosives in the region.
Abstract: Disclosed is a composition comprising MZ for use as a dietary supplement or food additive for oral consumption for improving the visual performance of a human subject.
Type:
Grant
Filed:
December 2, 2013
Date of Patent:
February 24, 2015
Assignee:
Howard Foundation Holdings Limited
Inventors:
John Nolan, Stephen Beatty, James Loughman, Alan N. Howard, David Thurnham
Abstract: A process and corresponding apparatus and system for use in preparing soaps from fatty acid containing oil compositions, and in turn, for preparing greases by the use of such soaps in combination with one or more base oils.
Type:
Grant
Filed:
April 22, 2010
Date of Patent:
February 24, 2015
Assignee:
University of Northern Iowa Research Foundation
Abstract: A method for removing ammonia from a gas stream divides the gas steam into a plurality of separate gas streams and sprays a dilute acid solution into the streams. The acid solution is aqueous sulfuric acid and ammonium sulfate is produced. A device is used to divide the gas stream, the device having a plurality of conduits in fluid communication with a plenum. Spray nozzles are located in each conduit to spray the acid solution into the gas streams. The device creates less than 10 Pa back pressure to the gas stream.
Type:
Grant
Filed:
September 25, 2013
Date of Patent:
February 24, 2015
Assignee:
Ohio State Innovation Foundation
Inventors:
Lingying Zhao, Lara Jane S. Hadlocon, Roderick Manuzon
Abstract: Provided is an image processing apparatus. The image processing apparatus may perform an intersection test for rendering of a ray tracing scheme. The image processing apparatus may include a first calculator and a second calculator. The first calculator may perform a ray-plane test to determine whether a ray intersects a plane including a primitive and a barycentric test to determine whether the ray intersects the primitive. The second calculator may calculate a hit point based on the ray which intersects the primitive.
Type:
Grant
Filed:
June 6, 2011
Date of Patent:
February 24, 2015
Assignees:
Samsung Electronics Co., Ltd., Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
Chan Min Park, Tack Don Han, Jeong Soo Park, Jae Ho Nah, Yun Hye Jung
Abstract: A method to produce levulinic acid (LA) and gamma-valerolactone (GVL) from biomass-derived cellulose or lignocellulose by selective extraction of LA using GVL and optionally converting the LA so isolated into GVL, with no purifications steps required to yield the GVL.
Type:
Grant
Filed:
December 15, 2011
Date of Patent:
February 24, 2015
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
James A. Dumesic, Stephanie G. Wettstein, David Martin Alonso, Elif Ispir Gurbuz
Abstract: Embodiments of the subject invention relate to an air vehicle and a power source. Embodiments can operate at reasonable power levels for hovering and withstanding expected wind gusts. Embodiments can have a diameter less than 15 cm. Embodiments can have one or more smooth (continuous curvature) surface and can be operated using electromagnetic and electrohydrodynamic principles. The wingless design of specific embodiments can allow operation with no rotating or moving components. Additional embodiments can allow active response to the surrounding flow conditions. The issue of low lift to drag ratio and degradation of airfoil efficiency due to the inability of laminar boundary layers attachment can also be significantly reduced, or eliminated. The electromagnetic force can be generated by applying a pulsed (alternating/rf) voltage between a set of grounded and powered electrodes separated by a polymer insulator, dielectric, or other material with insulating properties.
Type:
Grant
Filed:
December 19, 2012
Date of Patent:
February 24, 2015
Assignee:
University of Florida Research Foundation, Inc.
Abstract: Disclosed is a pharmaceutical natural composition containing both statin compounds (mevinolin and mevinolinic acid) serving as cholesterol biosynthesis inhibitors and coenzyme Q (ubiquinone-10: CoQ10 and ubiquinone-9: CoQ9) compounds which are substances that inhibit factors causing complications such as myalgia involved in long-term use of the statin, prepared using Monascus sp. and natural medicinal substances such as ginseng, mushrooms and cereals.
Type:
Grant
Filed:
December 28, 2009
Date of Patent:
February 24, 2015
Assignee:
Sungshin Women's University Industry-Academic Cooperation Foundation
Abstract: Disclosed is a novel family of macrocyclic compounds, coined calixurenes, which comprises linear and cyclic oligomers composed of alternating moieties of an aromatic unit and a ureatic unit, linked to one another via a bridging moiety. The disclosed calixurenes feature multiple heteroatom-containing groups, and can be designed so as to feature other functionalities, and can thus be used in a variety of applications. Further disclosed are processes of preparing the calixurenes, articles containing same and uses thereof.
Type:
Grant
Filed:
August 12, 2010
Date of Patent:
February 24, 2015
Assignee:
Technion Research & Development Foundation Limited
Abstract: Described herein are compounds that may be selectively activated to produce active anti-cancer agents in tumor cells. Also disclosed are pharmaceutical compositions comprising the compounds, and methods of treating cancer using the compounds.
Abstract: A logic device may include a first functional block, the first functional block including, a first storage block, a second storage block, and a first function controller. In a first operation time period, the first function controller may be configured to receive a first configuration selection signal and a first configuration command signal that instructs a first function be configured, select the first storage block as a configured storage block in the first operation time period based on the first configuration selection signal, and configure the first function in the first storage block based on the first configuration command signal.
Type:
Grant
Filed:
August 29, 2012
Date of Patent:
February 24, 2015
Assignees:
Samsung Electronics Co., Ltd., University of Seoul Industry Cooperation Foundation
Inventors:
Hyun-sik Choi, Ho-jung Kim, Ki-chul Kim, Jai-kwang Shin, Joong-ho Choi, Hyung-su Jeong
Abstract: A process for producing proppants from waste mineralogical material. The process can include providing the waste mineralogical material in a form such as particles, fines, dust, powders, and the like, and forming a plurality of “green” pellets from the waste mineralogical material. Thereafter, the plurality of green pellets are fed into a provided flame drop tower that has a combustion flame, a hot zone, and a collection basin located downstream from the hot zone. The plurality of green pellets pass through the hot zone, are melted and subsequently solidified in the shape of a sphere downstream from the hot zone to form vitrified glass spheres. In some instances, the vitrified glass spheres are subjected to a devitrification step.
Type:
Grant
Filed:
January 17, 2013
Date of Patent:
February 24, 2015
Assignee:
The Penn State Research Foundation
Inventors:
Ryan P. Koseski, John R. Hellmann, Barry E. Scheetz
Abstract: Mutant fibroblast growth factor (FGF) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the Fgf-1 subfamily of genes from a mammalian species, such as human, and with a specific amino acid substitution of an alanine at a position corresponding to amino acid position 66 of human FGF-1 with a cysteine and/or a specific amino acid substitution of a phenylalanine at a position corresponding to amino acid position 132 of human FGF-1 with a tryptophan (based on the 140 amino acid numbering scheme of human FGF-1) are provided. Other amino acid mutations or substitutions may be combined. Polynucleotide sequences encoding the mutant FGF proteins and host cells containing such polynucleotide sequences are provided. Methods of administering a mutant FGF protein to an individual to treat an ischemic condition or disease or a wound or tissue injury are also provided.
Type:
Grant
Filed:
November 6, 2012
Date of Patent:
February 24, 2015
Assignee:
Florida State University Research Foundation
Abstract: Androgen receptor-based vaccines for eliciting an immune reaction in vivo against cells expressing androgen receptor are disclosed. The vaccines are useful in the treatment of prostate cancer. Also disclosed are methods for inducing immune reaction to androgen receptor or treating prostate cancer in a mammal, using the vaccines and pharmaceutical compositions comprising the vaccines.
Abstract: The subject invention provides advantageous systems and processes for anaerobic digestion of organic waste streams, particularly agricultural waste streams. According to this invention, a new process is provided in which a liquid fraction from an organic waste stream comprising soluble compounds is segregated and incubated in a reactor separate from the solids fraction of the organic waste stream. Digestion of waste in both reactors occurs substantially simultaneously and both reactors produce biogas (thus both reactors function essentially like single stage reactors but allow for continuous or intermittent loading). According to one aspect of the invention, at least one cross-flow baffle is provided for use in an anaerobic digester to collect biogas and break up clumped solids in the reactor. In another aspect of the invention, packing media for use in an anaerobic digester is provided.
Type:
Grant
Filed:
March 14, 2013
Date of Patent:
February 24, 2015
Assignee:
University of Florida Reearch Foundation, Inc.
Inventors:
Pratap Pullammanappallil, Kerry Johanson, Ioannis Martinos Polematidis, John M. Owens, David P. Chynoweth
Abstract: Devices for production of electricity and/or hydrogen gas are provided by the present invention. In particular, microbial fuel cells for production of electricity and modified microbial fuel cells for production of hydrogen are detailed. A tube cathode is provided which includes a membrane forming a general tube shape. An anode is provided which has a specific surface area greater than 100 m2/m3. In addition, the anode is substantially non-toxic to anodophilic bacteria. Combinations of particular anodes and cathodes are included in microbial fuel cells and modified microbial fuel cells.