Abstract: A method of verifying authenticity of a speculative control-flow instruction is disclosed which includes receiving a new speculative source-destination pair (PAIR), checking the PAIR against one or more memory tables each having memory source-destination pairs associated with previous combinations of source-destination pairs that have successfully cleared as non-speculative source-destination pairs, if the PAIR exists in the one or more memory tables, fetching the instruction associated with the destination, if the PAIR does not exist in the one or more memory tables i) waiting until speculation of the source has cleared as being non-speculative or one or more program counter clock cycles later, ii) updating the one or more memory tables, wherein the updating is associated with inclusion of the PAIR as a new authentic pair, and iii) fetching the non-speculative destination, and if the speculation of the source does not clear as non-speculative, then the source is nullified.

Abstract: There is provided a method and an apparatus capable of generating contrast-enhanced medical images that clearly show contrast-enhanced areas from non-contrast medical images of cross-sections of a patient's body provided by a medical imaging apparatus such as a CT scanner using a neural network model.

Abstract: Disclosed are an RF bio-sensor and a method for manufacturing the same, in which DNA may be detected in real time, which may greatly improve detection efficiency, and a relatively simple manufacturing method and detection method are used, and signal media materials can be reused, thus making it excellent in terms of economic efficiency, and the bio-sensor does not rely on enzymes or chemical reactions, but uses only high-frequency electrical signal analysis, thus not requiring labels and thus significantly reducing contamination problems.

Abstract: A method of manufacturing a liquid metal film using an imbibition phenomenon is provided. The method includes forming a microstructure on a polymer substrate, preparing a microstructured metal substrate by depositing a metal on the polymer substrate on which the microstructure is formed, and coating the microstructured metal substrate with a liquid metal.

Abstract: An inflammasome activates caspase-1 for cytokine maturation and cell death, and thus induces host defense in cells. An NLRP3 inflammasome promotes the release of highly inflammatory cytokines IL-1? and IL-18 to induce gasdermin D-mediated pyroptosis (pyroptotic cell death), and thus is involved in inflammatory processes. Therefore, targeting an NLRP3 pathway and modulating relevant immune responses can be a promising strategy for designing drug candidates for inflammatory diseases. A rationally designed ?2-helix-based peptide NIP3 inhibits the NLRP3 pathway. NIP3 has remarkably inhibited both the secretion of NLRP3-induced IL-1? and IL-18 and the expression of downstream proteins in lipopolysaccharide-primed nigericin-activated THP-1 cells. In addition, binding energy data suggests that NIP3 has a stronger affinity for ASCPYD than for NLRP3PYD. Therefore, according to empirical and in silico results, NIP3 exclusively inhibits the NLRP3-ASC-caspase-1 pathway.

Abstract: This document describes methods and materials for treating ventricular fibrillation. For example, this document describes methods and devices for electroporation of Purkinje tissue to treat ventricular fibrillation.

Abstract: The present disclosure relates to a carbon dioxide conversion apparatus for preparing carbon monoxide: including an oxidation electrode; a reduction electrode opposing and spaced apart from the oxidation electrode; and an ion-exchange membrane disposed between the oxidation electrode and the reduction electrode, wherein the oxidation electrode includes a hydrogen oxidation reaction (HOR) catalyst, and the reduction electrode is a gas diffusion electrode including a metal nanocluster catalyst, and an electrochemical carbon dioxide conversion method using the same. According to the present disclosure, the electrical energy required for conversion of carbon dioxide can be decreased significantly and the selectivity for carbon monoxide can be improved.

Abstract: A method to make mono- or di-hydroxy-hexanoates. Triacetic acid lactone is converted to a ?-hexalactone or a 4-hydroxy-?-hexalactone intermediate. The intermediate is treated with an acid in the presence of an alcohol to yield a 5-hydroxy-hexanoate or 4,5-dihydroxy-hexanoate.

Abstract: A cartridge for virus detection and a system for virus detection are disclosed. The cartridge includes a sample chamber capable of accommodating therein a sample solution containing therein magnetic beads capable of fixing a virus thereto, wherein a control hole is formed at the sample chamber; a lysis chamber connected to the sample chamber via a channel and capable of receiving the sample solution therefrom, wherein a lysis reaction is carried out in the lysis chamber; and a detection flow path having one or more first degassing holes formed at a downstream end thereof, wherein the detection flow path is capable of extracting the sample solution free of the magnetic beads from the lysis chamber under a negative pressure generated by an interaction between the control hole and the first degassing hole, and of detecting the virus therefrom.

Abstract: A substrate processing apparatus includes a substrate stage configured to support a semiconductor substrate, the substrate stage being rotatable at a predetermined angular velocity, and a discharge device above the substrate stage, the discharge device being configured to discharge a chemical solution onto the semiconductor substrate, and the discharge device including a nozzle arm movable along a radial direction from a central region of the substrate stage to a peripheral region surrounding the central region, a nozzle on the nozzle arm, the nozzle facing the substrate stage, and the nozzle being configured to discharge the chemical solution onto the semiconductor substrate at a predetermined angle relative to a surface of the semiconductor substrate, and an angle changer configured to change the predetermined angle such that the predetermined angle gradually decreases as the nozzle arm moves from the central region to the peripheral region.

Abstract: Disclosed is a method for delivering digital therapeutics. A method for delivering digital therapeutics according to an embodiment of the present invention may comprise the steps of: determining the degree of emotional disorder of a patient on the basis of diagnosis information and digital therapeutics usage information of the patient; determining digital therapeutics to be delivered to the patient according to the determined degree of emotional disorder, and delivering the determined digital therapeutics to a user terminal of the patient.

Abstract: Provided are bacterial minicells derived from genome reduced (GR) having a reduced number of expressed genes and/or is a bacterium having one or more mutated min genes. In some embodiments, the minicell has a recombinant protein present in and/or on the surface of the minicell. In some embodiments, the recombinant protein is an antigen and in some embodiments, the minicell induces an enhanced immune response against the antigen when administered to a subject. In some embodiments, the bacterium has an autotransporter (AT) expression vector encoding the recombinant protein to express the recombinant protein on the surface of the bacterium and/or the minicell derived therefrom. Also provided are vaccine compositions that include bacterial minicells, methods for producing antibodies, methods for vaccinating subjects, and expression vectors encoding heterologous proteins.

Abstract: The present invention discloses the use of benzene derivatives as immunosuppressants. The benzene derivatives as immunosuppressants are represented by Formula 1: wherein R is a linear alkyl group, a branched alkyl group or an alkyl group containing one or more carbon-carbon double bonds, X is an amide or ester group, and Y is a halo, methoxy, ethoxy, hydroxyl or nitro group. The benzene derivatives are used in the preparation of immunosuppressive medicaments. The benzene derivatives are effective for treating T cell-mediated immune diseases, for example, for preventing and treating rejection after organ and bone marrow transplantation and treating T cell-mediated autoimmune diseases, psoriasis, multiple sclerosis, rheumatoid arthritis, insulin-dependent diabetes mellitus, specific hemolytic anemia, ulcerative colitis, myasthenia gastrica, glomerulonephritis, Guillain-Barre syndrome, and allergic diseases such as allergic asthma and atopy due to their ability to inhibit the proliferation of T lymphocytes.

Abstract: A system for integrating a plurality of biosensor devices includes one or more communication interfaces adapted to communicate with each of the plurality of biosensor devices connected to a subject, and a processor executing software on a non-transitory memory to: establish a communication link with each of the plurality of biosensor devices, receive biodata from each of the plurality of biosensor devices through the one or more communication interfaces at a sampling rate, assign a timestamp to the received biodata such that the received data from the plurality of biosensor devices are synchronized, receive environmental data via one or more environmental sensors, store received biodata along with the assigned timestamp into a database and the environmental data, analyze stored data along with the assigned timestamp to predict an evoked response to one or more stimuli and the environmental data and provide a feedback based on the analysis.

Abstract: The present invention relates to a dry adhesive patch including a first layer flexible and having a structure with embossed or engraved structures on one surface, a second layer flexible and comprising an interlocking coupling surface formed to engage with the embossed or engraved structures of the first layer, and a microchannel structure layer stacked on the opposite surface of the interlocking coupling surface, wherein the microchannel structure layer comprises an adhesive surface comprising a plurality of embossed portions having a flat surface and microchannel grooves between the embossed portions and is exposed.

Abstract: There is provided a device for controlling an automatic checkout system. The device comprises a storage medium configured to store a product detection model trained based on training images in which parameters of a plurality of sample images are manipulated and one or more commands; and a processor configured to execute the one or more commands stored in the storage medium, wherein the instructions, when executed by the processor, cause the processor to: sequentially load a plurality of frame images, input the plurality of loaded frame images into the product detection model, detect at least one product from each of the plurality of frame images, track at least one product detected in each frame image, and count at least one product detected based on a tracking result.

Abstract: According to an embodiment, an IPL sterilization device includes a lamp configured to output light including a visible light region to sterilize a region including a surface of an object; a capacitor configured to transmit a voltage charged to the lamp; and a controller configured to control the capacitor, wherein the controller is configured to: control the lamp to be driven in an outputable state or an unoutputable state, change the lamp to the unoutputable state when the object satisfies an object overheat condition in the outputable state, and change the lamp to the outputable state when the object unsatifies the object overheat condition after the lamp satisfies the object overheat condition and changes the lamp to the unoutputable state, wherein the outputable state is a state in which the lamp is capable of outputting light by applying a driving pulse to the lamp by the capacitor, and the unoutputable state is a state in which the lamp is not capable of outputting light because the capacitor does not o

Abstract: The invention relates to compounds, compositions, and methods of treating viral infection, especially SARS-CoV-2 infection.

Abstract: A binary code similarity detection device performs a preprocessing operation of generating an assembly expression for the binary code by converting a machine language of an input binary code into an assembly language, extracting an assembly function or a command from the binary code converted to the assembly language, and detects a similarity to the assembly expression of a pre-stored binary code by inputting the assembly expression generated by the preprocessing operation to a trained model based on bidirectional encoder representations from transformers (BERT), and the trained model is generated by performing a pre-training step of causing the assembly expression to be understood and a fine-tuning step of inputting an assembly expression of a first binary code and an assembly expression of a second binary code to a pre-trained model and then fine-tuning the pre-trained model based on a similarity between the first binary code and the second binary code.

Abstract: The present invention relates to an isoxazole derivative or a pharmaceutically acceptable salt thereof, and to a composition comprising said derivative as an active ingredient for preventing or treating diseases associated with CSF-1R. The isoxazole derivative of the present invention inhibits CSF-1R, and therefore can be used as a disease associated with CSF-1R for preventing or treating degenerative brain diseases.