Patents Assigned to Foundation
  • Motion tracking system for real time adaptive imaging and spectroscopy
    Patent number: 8571293
    Abstract: This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P).
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: October 29, 2013
    Assignees: The Queen's Medical Center, The University of Hawaii, The Medical College of Wisconsin, Inc., UWM Research Foundation, Inc.
    Inventors: Thomas Michael Ernst, Thomas Edmund Prieto, Brian Stewart Randall Armstrong
  • Targeting complement factor H for treatment of diseases
    Patent number: 8569225
    Abstract: The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: October 29, 2013
    Assignees: MUSC Foundation for Research Development, The Regents of the University of Colorado, a body corporate
    Inventors: Gary Gilkeson, Stephen Tomlinson, V. Michael Holers, Baerbel Rohrer
  • Method of detecting compromised computers in a network
    Patent number: 8572197
    Abstract: A method of detecting a compromised machine on a network. The method receives an email message from a machine on the network and classifies it as either spam or non-spam. A probability ratio is then updated, according to whether the message was spam or non-spam, by applying a sequential probability ratio test. If the probability ratio is greater than or equal to a first threshold, then the machine is compromised. If the probability ratio is less than or equal to a second threshold, then the machine is normal. The operations of receiving a message, classifying the message, updating the probability ratio, and indicating the machine is normal or compromised until the probability ratio is greater than or equal to the first threshold are repeated for a plurality of messages. Such repeated operations are performed on each of the messages one at a time, as each of the messages is received.
    Type: Grant
    Filed: October 1, 2012
    Date of Patent: October 29, 2013
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Zhenhai Duan, Peng Chen
  • Materials and methods for the production of biodiesel
    Patent number: 8569021
    Abstract: The subject invention provides novel microorganisms comprising polynucleotides and polypeptides encoding a methyltransferase. The subject invention provides novel methods for the production of biodiesel.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: October 29, 2013
    Assignee: University of Tennessee Research Foundation
    Inventors: Feng Chen, Nan Zhao
  • BPMV-based viral constructs useful for VIGS and expression of heterologous proteins in legumes
    Patent number: 8569579
    Abstract: The invention provides Bean pod mottle virus (BPMV) vectors useful for expression of heterologous proteins in plants such as soybean. The BPMV vectors are also useful for virus-induced gene silencing. The vectors of the invention include modifications of BPMV RNA1 sequences so that infection with the vectors produces only moderate symptoms. The vectors also comprise novel RNA2 vectors which specifically provide for non-translated VIGS constructs and further which do not require in frame insertion of heterologous sequences to be expressed.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: October 29, 2013
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: John H. Hill, Chunquan Zhang, Steve Whitham
  • Nanowire fabrication
    Patent number: 8568876
    Abstract: Techniques for making nanowires with a desired diameter are provided. The nanowires can be grown from catalytic nanoparticles, wherein the nanowires can have substantially same diameter as the catalytic nanoparticles. Since the size or the diameter of the catalytic nanoparticles can be controlled in production of the nanoparticles, the diameter of the nanowires can be subsequently controlled as well. The catalytic nanoparticles are melted and provided with a gaseous precursor of the nanowires. When supersaturation of the catalytic nanoparticles with the gaseous precursor is reached, the gaseous precursor starts to solidify and form nanowires. The nanowires are separate from each other and not bind with each other to form a plurality of nanowires having the substantially uniform diameter.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: October 29, 2013
    Assignee: Korea University Research and Business Foundation
    Inventor: Kwangyeol Lee
  • Substituted 3-(1H-benzo[d]imidazol-2-yl)-1H-indazole analogs as inhibitors of the PDK1 kinase
    Patent number: 8569511
    Abstract: In one aspect, the invention relates to substituted 3-(1H-benzo[d]imidazol-2-yl)-1H-indazole analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the PDK1 kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions for treating disorders associated with dysfunction of the PDK1 kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: March 31, 2012
    Date of Patent: October 29, 2013
    Assignee: University of Utah Research Foundation
    Inventors: David J. Bearss, Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Sunil Sharma
  • Image interpolation method and apparatus using pattern characteristics of color filter array
    Patent number: 8571312
    Abstract: An image interpolating method and apparatus, in which horizontal and vertical Differences of Absolute Inter-channel Differences (DAIDs) are calculated from a color filter array (CFA) image, and an unknown pixel is interpolated in horizontal and vertical directions estimated in consideration of the DAIDs of R, G, and B pixels. Therefore, the image interpolating method and apparatus provide a large Peak Signal and Noise Ratio (PSNR), a Structural Similarity (SSIM), and high visual quality images.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: October 29, 2013
    Assignees: Samsung Electronics Co., Ltd., Industry-University Cooperation Foundation Sogang University
    Inventors: Soon-keun Chang, Rae-hong Park, Ji-won Lee
  • Accumulation field effect microelectronic device and process for the formation thereof
    Patent number: 8569834
    Abstract: A gated microelectronic device is provided that has a source with a source ohmic contact with the source characterized by a source dopant type and concentration. A drain with a drain ohmic contact with the drain characterized by a drain dopant type and concentration. An intermediate channel portion characterized by a channel portion dopant type and concentration. An insulative dielectric is in contact with the channel portion and overlaid in turn by a gate. A gate contact applies a gate voltage bias to control charge carrier accumulation and depletion in the underlying channel portion. This channel portion has a dimension normal to the gate which is fully depleted in the off-state. The dopant type is the same across the source, drain and the channel portion of the device. The device on-state current is determined by the doping and, unlike a MOSFET, is not directly proportional to device capacitance.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: October 29, 2013
    Assignee: The Penn State Research Foundation
    Inventors: Stephen J. Fonash, Yinghui Shan, Somasundaram Ashok
  • White-emitting compounds using excited-state intramolecular proton transfer, organic electroluminescent element and laser material using the same
    Patent number: 8569510
    Abstract: Provided are a white-emitting monomolecular compound using excited-state intramolecular proton transfer (ESIPT) characteristics, and an organic electroluminescence device and a laser device comprising same. The white-emitting monomolecular compound according to the present invention is prepared by covalently bonding at least two types of molecules which produce different colors and have excited-state intramolecular proton transfer (ESIPT) characteristics. The white-emitting monomolecular compound according to the present invention achieves white luminescence irrespective of the concentration thereof and of the state of the materials thereof, and therefore can be used in a variety of fields including an organic electroluminescence device and a laser device.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: October 29, 2013
    Assignees: Dongwoo Fine-Chem Co. Ltd., SNU R&DB Foundation
    Inventors: Soo Young Park, Sang Hyuk Park, Ji Eon Kwon
  • Quantum cascade lasers with electrically tunable emission wavelengths
    Patent number: 8571082
    Abstract: The present invention provides a QCL device with an electrically controlled refractive index through the Stark effect. By changing the electric field in the active area, the energy spacing between the lasing energy levels may be changed and, hence, the effective refractive index in the spectral region near the laser wavelength may be controlled.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: October 29, 2013
    Assignees: Maxion Technologies, Inc., The Research Foundation of State University of New York, Board of Regents, The University of Texas System
    Inventors: Gregory Belenky, John D. Bruno, Mikhail V. Kisin, Serge Luryi, Leon Shterengas, Sergey Suchalkin, Richard L. Tober, Mikhail Belkin
  • Cyclin dependent kinase inhibitors
    Patent number: 8569356
    Abstract: The invention relates to cyclin dependent kinase inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions for treating cell proliferative disorders, especially cancer.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: October 29, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: David A. Ostrov, Brian K. Law, Patrick Corsino
  • Protease inhibitors, compositions and methods of use
    Patent number: 8569245
    Abstract: This invention relates to grassystatins A, B and C, and their isolated or purified forms. The compounds of the invention are useful as aspartic protease, gamma secretase, or metalloprotease inhibitors. Methods of using the compounds and compositions thereof are also disclosed.
    Type: Grant
    Filed: June 26, 2010
    Date of Patent: October 29, 2013
    Assignees: University of Florida Research Foundation, Inc., Smithsonian Institution
    Inventors: Hendrik Luesch, Valerie J. Paul, Jason C. Kwan
  • User-based collaborative filtering recommendation system and method for amending similarity using information entropy
    Patent number: 8572017
    Abstract: The present invention relates to a user-based collaborative filtering recommendation method and system and, more specifically, relates to a user-based collaborative filtering recommendation method and system which amends the similarity between the recommend probable user and the other user to improve the accuracy in the prediction of preference by using the relation between the user preference information entropies of the recommend probable user and the other user.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: October 29, 2013
    Assignee: Sungkyunkwan University Foundation For Corporate Collaboration
    Inventors: Kwang Seok Hong, Hyeong Joon Kwon
  • Water toxicity detecting apparatus and method using sulfur particles
    Patent number: 8569045
    Abstract: Provided are a water toxicity detecting apparatus and a method using sulfur particles.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: October 29, 2013
    Assignee: University-Industry Cooperation Foundation, Kangwon University
    Inventor: Sang Eun Oh
  • Variable focus liquid lens
    Patent number: 8570659
    Abstract: A variable focus liquid lens includes: a lens barrel which is configured to include a first cavity to contain first and second liquids which are not mixed with each other in upper and lower portions of the first cavity, respectively; a fluid pressure driving unit which is configured to include a second cavity, a fluid pressure generating groove, and an actuator generating a fluid pressure on the second liquid so as to adjust the fluid pressure of the second liquid by using the actuator; a first transparent elastic membrane sealing an upper portion of the first cavity of the lens barrel; and a conductive transparent substrate sealing a lower portion of the second cavity of the fluid pressure driving unit. The focal length is adjusted by changing the curvatures of the surfaces of the first and second liquids and the curvature of the first transparent elastic membrane by a voltage.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: October 29, 2013
    Assignee: Kyungpook National University Industry-Academic Cooperation Foundation
    Inventors: Seong Ho Kong, Hak-Rin Kim, June Kyoo Lee, Kyung-Woo Park
  • System and methods for multi-object multi-surface segmentation
    Patent number: 8571278
    Abstract: A system and methods for the efficient segmentation of globally optimal surfaces representing object boundaries in volumetric datasets is provided. An optical surface detection system and methods are provided that are capable of simultaneously detecting multiple interacting surfaces in which the optimality is controlled by the cost functions designed for individual surfaces and by several geometric constraints defining the surface smoothness and interrelations. The present invention includes surface segmentation using a layered graph-theoretic approach that optimally segments multiple interacting surfaces of a single object using a pre-segmentation step, after which the segmentation of all desired surfaces of the object are performed simultaneously in a single optimization process.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: October 29, 2013
    Assignee: The University of Iowa Research Foundation
    Inventors: Milan Sonka, Xiaodong Wu, Yin Yin, Xiangmin Zhang
  • Method for modifying lignin structure using monolignol ferulate conjugates
    Patent number: 8569465
    Abstract: Described is an isolated lignified plant cell wall including lignin, wherein the lignin includes a ferulate residue incorporated therein, such as from coniferyl ferulate and/or sinapyl ferulate. Also described is a method to make the isolated lignified plant cell wall, and the lignin produced by the method.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: October 29, 2013
    Assignees: Wisconsin Alumni Research Foundation, The United States of America, as represented by the Secretary of Agriculture
    Inventors: John Ralph, John H. Grabber, Ronald D. Hatfield, Fachuang Lu
  • Attack resistant continuous network service trustworthiness controller
    Patent number: 8572735
    Abstract: An attack resistant continuous network service trustworthiness controller comprising: state estimation module(s), response selection module(s), actuation module(s), and client dispatcher communication module(s) for maintaining the availability and integrity of online server(s). The state estimation module(s) are configured to generate state estimate(s) for online server(s) using behavior data obtained using sensor module(s). The response selection module(s) are configured to determine corrective action(s) to maintain the availability and integrity of online server(s) when state estimate(s) indicate that the integrity of an online server(s) is compromised. The actuation module(s) are configured to activate actuator(s) based upon the corrective action(s). Client dispatcher communication module(s) are configured to communicate online server availability information to a client dispatcher.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: October 29, 2013
    Assignee: George Mason Research Foundation, Inc.
    Inventors: Anup K. Ghosh, Yih Huang, Arun Sood
  • STREAMING SERVICE TRANSMITTING/RECEIVING DEVICE AND METHOD
    Publication number: 20130282871
    Abstract: Provided is an apparatus and method for transmitting and receiving a streaming service. An inter-arrival jitter may correspond to a delay variation in arrival time between TCP packets arriving at an apparatus for receiving the streaming service. The apparatus for receiving the streaming service may determine a de-jitter buffering time to absorb a network jitter before TS packets in a TCP packet is input to a T-STD buffer model. Based on the de-jitter buffering time, an initial playout delay lime at the apparatus for receiving the streaming service may be determined.
    Type: Application
    Filed: October 20, 2011
    Publication date: October 24, 2013
    Applicants: Industry-Academy Cooperation Foundation,Yonsei University, Electronics and Telecommunictions Research Instutute
    Inventors: Soon Heung Jung, Kwang Deok Seo, Jin Young Lee, Seong Jun Bae, Jung Won Kang, Sang Woo Shim, Truong Cong Thang, Sang Taick Park, Won Ryu