Abstract: The invention provides methods for the treatment of major depressive disorder in male subjects and methods for the treatment of psychiatric disorders at high altitudes by administering one or more creatine-containing compounds.

Abstract: The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a sensitizing agent followed by contacting the cell with a therapeutic RNAi agent.

Abstract: The invention relates to novel metal complexes useful as catalysts in redox reactions (such as, hydrogen (H2) production). In particular, the invention provides novel transition metal (e.g., cobalt (Co) or nickel (Ni)) complexes, in which the transition metal is coupled with N,N-Bis(2-pyridinylmethyl)-2,2?-Bipyridine-6-methanamine (DPA-Bpy), 6?-((bis(pyridin-2-ylmethyl)amino)methyl)-N,N-dimethyl-2,2?-bipyridin-6-amine (DPA-ABpy), or a derivative thereof. The invention also relates to a method of producing H2 from an aqueous solution by using the metal complex as a catalyst. In certain embodiments, the invention provides a metal complex of the formulae as described herein.

Abstract: Dual action lethal containers, systems, methods, compositions and formulas used to kill mosquitoes and their larvae. The containers can have separate interior larvicidal and adulticidal coatings separated from each other by horizontal water line holes in the container. Another container can use a novel combined coating of a larvicidal and adulticidal coating. Unique compositions of adulticidal coatings, larvicidal coatings and combined adulticidal and larvicidal coatings can be used as liners.

Abstract: Anti-angiogenic agents or polypeptides comprising an amino acid segment substantially similar to domain one of CD2 wherein the polypeptide has a ?-sheet formed by two segments. Methods of using such agents and polypeptide are also included.

Abstract: The method of testing for presence of a bug a multithreaded computer program under verification combines the efficiency of testing with the reasoning power of satisfiability modulo theory (SMT) solvers for the verification of multithreaded programs under a user specified test vector. The method performs dynamic executions to obtain both under- and over-approximations of the program, represented as quantifier-free first order logic formulas. The formulas are then analyzed by an SMT solver which implicitly considers all possible thread interleavings. The symbolic analysis may return the following results: (1) it reports a real bug, (2) it proves that the program has no bug under the given input, or (3) it remains inconclusive because the analysis is based on abstractions. In the last case, a refinement procedure is presented that uses symbolic analysis to guide further executions.

Abstract: The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as methods of modulating bone processes, and methods of treating bone-related disease, disorders, and symptoms thereof.

Abstract: Methods for derivatizing the surface of a substrate having a plurality of thiol groups thereon are disclosed herein. The method can include reacting the thiol groups with an o-quinone methide, which can optionally be generated by irradiating an o-quinone methide precursor compound. In some embodiments, the method can advantageously be reversible. Exemplary o-quinone methides having a cyclic alkyne attached thereto, and precursor compounds for generating such compounds, are also disclosed herein.

Abstract: Disclosed are methods for controlling molecular interactions where at least one member of a pair of chemical entities having a pH-dependent affinity is immobilized on the surface of an electrode. By changing the potential difference between the electrode and a counter electrode, the affinity of the pair of chemical entities is changed, changing the tendency of the pair to bind or to dissociate. Disclosed are also devices useful for implementing the methods of the present invention.

Abstract: Nanoelectromechanical devices use a cantilevered beam supported by a base. The cantilevered beam is constructed with a nanoscale gap (e.g., less than 10 nm) separating the cantilevered beam from an electrical structure. A low voltage (e.g., less than 2 volts) applied to the cantilevered beam can cause the beam to bend and make contact with the electrical structure. High switching speeds (e.g., less than 10 ns) can be provided. The electrical structure can be a second cantilevered beam or another structure.

Abstract: This invention relates to processes for preparing long-chain fatty acids of Formula I: and salts thereof, as well as intermediates for the processes, wherein L1 and L2 are described herein.

Abstract: A method of making Y-type hexagonal ferrite and an antenna using the same are provided. Y-type hexagonal ferrite includes a base ferrite composed of iron oxide, barium carbonate and cobalt oxide, and silicate glass ranging from 0.5 to 5 weight percent added to 100 weight percent of base ferrite. An antenna apparatus includes a magnetic carrier and an antenna pattern formed thereon. The magnetic carrier is formed of such Y-type hexagonal ferrite, and the antenna pattern resonates in a specific frequency band when electric power is supplied. To fabricate the Y-type hexagonal ferrite, a calcination process is performed in which iron oxide, barium carbonate and cobalt oxide are combined into base ferrite at a given calcination temperature after being mixed. A sintering process is performed to sinter the base ferrite and the silicate glass at a given sintering temperature which is lower than the calcination temperature after adding the silicate glass to the base ferrite.

Abstract: A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic photosensitizer and an imaging agent and methods for making and using same.

Abstract: The invention provides compositions (e.g., kits) and methods for determine the number of bacteria and other microbes in samples having low concentrations of microbes, for use, e.g., in biological warfare defense, microbe detection and agricultural and environmental sciences.

Abstract: The invention includes isolating pharmaceutical proteins from avian hard shell eggs containing pharmaceutical proteins wherein the pharmaceutical proteins are exogenous to the egg.

Abstract: Provided is a data reception error reduction system and method in acoustic communication in audible frequency range, and an apparatus applied thereto. The data reception error reduction system in the acoustic communication in audible frequency range may be configured to reduce a data reception error in a receiver by taking into consideration that a sound signal is noisy and is significantly affected by a change in the ambient environment when the acoustic communication is performed in the audio frequency band through modification of an audio signal or adding of a predetermined signal to an audio signal. Accordingly, the data reception error may be reduced in the receiver even in an environment where a sound signal is noisy and is significantly affected by a change in the ambient environment, and reliability of data transmission may increase.

Abstract: A receiver of a wireless communication system and method thereof include antennas configured to receive data, wherein the data comprises a preamble, a header, and a payload. The receiver also includes a synchronizer configured to perform time synchronization of the data received through corresponding paths of each antenna using corresponding preambles of the data. The receiver includes a header detector configured to detect a header from the data of each of the paths. A surviving path selector in the receiver is configured to select a signal of a surviving path from among the paths based on the header or the preamble. The receiver also includes combiner configured to combine the signal existing in the surviving path to demodulate the payload.

Abstract: An apparatus for creating and managing personalized services includes: a pre-processing unit for converting vendor- and device-specific sensor data into a normalized form; an analysis unit for determining a current state of entities being managed based on the normalized sensor data to thereby determine whether current services and/or resources that have been allocated to a user are being satisfied or not; and a personalization unit for examining state-related context data to determine what action to take. The personalization of the services and/or resources provided to a user or set of users is managed by context-sensitive policy rules. In addition, a set of abstractions, in the form of preferences, profiles, and subscriptions, are collectively used to determine the set of services and/or resources, as a function of context, that a user or set of users are entitled to receive.

Abstract: A method of stimulating neurons present in a living body is disclosed. The method comprises directing light to an artificial light absorbing medium implanted extracellularly at a target location having the neurons therein, wherein wavelengths and intensities of the light are selected so as to heat the light absorbing medium by light absorption. The heating is sufficient to stimulate neurons nearby the light absorbing medium. In some embodiments, the light is spatially modulating so as to encode a stimulation pattern therein.

Abstract: A method for preparing uniquely sized nanoparticles of CaF2 by simultaneously spray drying a first NH4F and a biocompatible salt solution and a second Ca(OH)2 and biocompatible salt solution to form CaF2 solid particles in a soluble salt matrix wherein the salt is more soluble than CaF2. The salt matrix may then be dissolved and the separate CaF2 nanosized particles collected for use as a dental therapeutic material. The technique is useful in the preparation of other discrete, nanoparticle sized compounds and combinations by carefully choosing the solvents and solutes of the two spray dried solutions.