Abstract: Disclosed are systems and methods for coupling translation of a target gene to a detectable response gene. A version of the invention includes a translation-coupling cassette. The translation-coupling cassette includes a target gene, a response gene, a response-gene translation control element, and a secondary structure-forming sequence that reversibly forms a secondary structure masking the response-gene translation control element. Masking of the response-gene translation control element inhibits translation of the response gene. Full translation of the target gene results in unfolding of the secondary structure and consequent translation of the response gene. Translation of the target gene is determined by detecting presence of the response-gene protein product.

Abstract: Multilayered films, particularly ultrathin multilayered films comprising cationic polymers which are useful for controlled release of anionic species, particularly for controlled release of nucleic acids. The multilayer films herein are useful for temporal controlled released of anionic species, particularly one or more anionic peptides, proteins, nucleic acids or other anionic biological agents. In one aspect, the invention relates to multilayer films which release anionic species (anions) with separate and/or distinct release profiles, particularly wherein the anions are one or more anionic peptides, proteins or nucleic acids or other anionic biological agents.

Abstract: A semiconductor device manufacturing method which achieves a contact of a low resistivity is provided. In a state where a first metal layer in contact with a semiconductor is covered with a second metal layer for preventing oxidation, only the first metal layer is silicided to form a silicide layer with no oxygen mixed therein. As a material of the first metal layer, a metal having a work function difference of a predetermined value from the semiconductor is used. As a material of the second metal layer, a metal which does not react with the first metal layer at an annealing temperature is used.

Abstract: Disclosed is a method for separating anthocyanins depleted in phenolic mixture content from fruits or vegetables feedstock containing anthocyanins and phenolic mixtures. The first step is to contact the feedstock with a cation-exchange resin at low pH for a time period effective for the resin to selectively bind with the anthocyanins. Next, the non-bound phenolic mixture is separated from the resin for recovery. The bound resin is subjected to solvent wash to release the anthocyanins for recovery.

Abstract: A method and system for distributing images for display by client systems. A distribution system includes an image server system that is connected to image client systems via a communications link, such as the Internet. The image server system is responsible for providing image packages to the image client systems and for collecting information from the image client systems. Each image client system periodically sends a heartbeat communication to the image server system. Upon receiving a heartbeat communication, the image server system determines the state of the image client system that sent the heartbeat communication and responds appropriately. The response may include instructions for the image client system to retrieve new images, to retrieve software updates, to send usage data, and so on.

Abstract: Disclosed herein is an advanced treatment system processing contaminated water or fouled water/waste water, and particularly, a system for membrane fouling control and reduction in the amount of sludge producing in a membrane combined-type fouled water/waste water advanced treatment system, and more particularly, a system capable of making sludge soluble using plasma and then re-utilizing cell byproducts of destructed sludge as a supply source of external carbon source, and possibly capable of removing a cake layer formed on a membrane using each kind of radical and ozone generated by plasma.

Abstract: A changeable liquid lens array and a method of manufacturing the same. The changeable liquid lens array includes a substrate, a plurality of partition walls arrayed on the substrate and having a fluid travel path, cells defined by the plurality of partition walls, a first fluid comprised in the cells, a second fluid arranged on the first fluid, a first electrode arranged on at least one side surface of each of the partition walls, and a second electrode disposed to be separate from the partition walls. A shape of an interface between the first fluid and the second fluid changes based on a voltage that is applied to the first electrode and the second electrode.

Abstract: A system and method for sound source separation. The system and method use a beamforming technique. The sound source separation system includes a windowing processor; a DFT transformer; a transfer function estimator; and a noise estimator. The system also includes a voice signal extractor that cancels individual voice signals, except an individual voice signal that is desired to be extracted among individual voice signals, from the integrated voice signals. The system further includes a voice signal detector that cancels a noise part provided through the noise estimator from a transfer function of an individual voice signal which is desired to be detected and extracts a noise-canceled individual voice signal. Even when two or more sound sources are simultaneously input, the sound sources can be separated from each other and separately stored and managed, or an initial sound source can be stored and managed.

Abstract: An upper stack for a nuclear magnetic resonance spectrometer apparatus includes a cryostat having one or more chambers for holding samples in a frozen state. A sample loading tube that also allows He delivery extends to the cryostat, and a sample changer mechanism is disposable at least in part proximate to the cryostat for moving specimens from the cryostat to an NMR probe where they can be heated and melted using inductive heating. A sample ejection tube extends from the sample changer mechanism allowing a clear path for heating a sample in an NMR probe using a laser beam.

Abstract: A method, computer program product and system are provided for modeling non-controllable parameters affecting system performance. The method may include receiving historical values for each of a plurality of system parameters and grouping the system parameters into controllable, non-controllable, and performance parameters. The method may further include determining a first set of predictors from the non-controllable parameters using the historical values of these non-controllable parameters and, for each predictor in the first set, determining optimal time instances at which a value of each predictor is measured using non-uniform time scales. These optimal time instances may then be saved as a second set of predictors. One or more constraints may then be established for each of the controllable parameters. Finally, a dynamic model based on the second set of predictors, the controllable parameters, and the performance parameters may be constructed and optimized.

Abstract: A non transitory computer readable medium and a method of detecting excavation of an underground tunnel, the method includes: propagating a light pulse through an underground optic fiber; generating detection signals responsive to Brillion scattered light resulting from the propagating of the light pulse through the underground optic fiber; wherein the detection signals represent tension values at multiple locations along the underground optic fiber; and processing the detection signals to detect excavation of the underground tunnel.

Abstract: The present invention relates to a solution-finding method, which finds an approximate solution of an equation having difficulty in obtaining an actual solution and a complicated equation in numerical analysis. The method obtains an approximate solution of an equation having a solution in a predetermined interval. Initial values are calculated based on upper and lower limits of the interval. The initial values are applied to a solution-finding equation, including a sign function and the upper and lower limits, and the solution-finding equation is arranged so that a definite integral formula for the sign function is included in the equation. The definite integral formula in the solution-finding equation is calculated using numerical integration, and results of the definite integral formula are applied to the solution-finding equation, thus obtaining an approximate solution. This performance is iterated until the approximate solution satisfies an allowable error.

Abstract: Provided is an optical sensing membrane, including a mixture of two or more fluorescent dyes for detection of dissolved oxygen concentration, pH and temperature, immobilized on a support, a detection device including the optical sensing membrane and a detection method using the detection device.

Abstract: A cast iron brake caliper with improved fatigue life, and a process and process equipment for pre-stressing a cast iron brake caliper to provide improved fatigue life, is provided. In the process, a load is applied to a cast iron caliper, where the load is high enough to locally yield and plastically deform the cast iron material, but not high enough to cause material failure, such as cracking. Upon load removal, residual compressive stresses in the cast iron caliper lower the mid-point of the stress range the plastically-deformed region of the caliper sees during in-service use, and thereby lowers the peak stress seen in this region, increasing fatigue life. The process permits a cast iron brake caliper to be designed to use less material and thus fit within constrained wheel rim envelopes, without the need to resort to high cost materials or other alternative design strategies.

Abstract: Provided is an apparatus and method for transmitting a channel sounding signal from a user terminal in a multiple antenna system. In the method, a channel for each of a plurality of antennas is estimated. The receiving signal power of each of the antennas is calculated using the channel information obtained through the channel estimation. The antenna with the highest RX signal power is selected. Therefore, it is possible to enhance the signal reception performance of the user terminal.

Abstract: A menu user interface providing device and a method thereof are disclosed. In accordance with an embodiment of the present invention, the method of providing a menu user interface by a portable apparatus, including determining whether a main menu icon displayed on a touch screen is selected; determining whether a menu mode is an activation mode or an inactivation mode if the main menu icon is selected; and changing the menu mode into the activation mode if the menu mode is determined as the inactivation mode and forming an expanded menu by radically arranging a submenu of n hierarchies, n being a natural number, corresponding to the main menu icon and displaying the formed expanded menu through a touch screen. Accordingly, with the present invention, a user interface capable of inputting various data with easy manipulation and minimized multi-points can be provided.

Abstract: The present invention relates to methods and systems for conducting three-dimensional image analysis and diagnosis and possible treatment relating thereto. The invention includes methods of handling signals containing information (data) relating to three-dimensional representation of objects scanned by a scanning medium. The invention also includes methods of making and analyzing volumetric measurements and changes in volumetric measurements which can be used for the purpose of diagnosis and treatment.

Abstract: The present disclosure relates to methods for detecting an increased risk of preeclampsia, determining the presence of preeclampsia, reducing the likelihood that preeclampsia will develop and treating preeclampsia. It also provides methods of measuring relaxin levels in a biological sample of a pregnant woman.

Abstract: Compounds of formula I are provided where X1 and X2 are independently selected from H or hydroxy protecting groups. Such compounds are used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.

Abstract: Inhibitors of AMPA-type glutamate ion channels are useful as biochemical probes for structure-function studies and as drug candidates for a number of neurological disorders and diseases. Disclosed herein is the identification of an RNA inhibitor or aptamer by an in vitro evolution approach and characterization of its mechanism of inhibition on the sites of interaction by equilibrium binding and on the receptor channel-opening rate by a laser-pulse photolysis technique. The aptamer of the invention is a noncompetitive inhibitor of AMPA-type glutamate ion channels, one that selectively inhibits the GluA2Qflip AMPA receptor subunit without any effect on other AMPA receptor subunits or on kainate or NMDA receptors. Furthermore, the aptamer preferentially inhibits the closed-channel state of GluA2Qflip with a KI=1.5 ?M or by ˜15-fold over the open-channel state. The potency and selectivity of this aptamer rival those of small molecule inhibitors.