Patents Assigned to Foundation
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Patent number: 8426620Abstract: Disclosed is a method for preparing a furan fatty acid, more particularly a method for preparing a furan fatty acid by heat-treating 7,10-dihydroxy-8(E)-octadecenoic acid (DOD) in hexane. The present disclosure provides a simple method for producing 7,10-EODA from a dihydroxyl fatty acid precursor. Considering the difficulties in purifying natural furan fatty acids because of easy attack by peroxyl radicals and small quantity and the complicated multiple steps for chemical synthesis, the present disclosure provides a useful way to produce the biologically activity F-acid cost-effectively in large scale.Type: GrantFiled: July 27, 2011Date of Patent: April 23, 2013Assignee: Kyungpook National University Industry-Academic Cooperation FoundationInventors: Hak ryul Kim, Joel B. Ellamar
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Patent number: 8426367Abstract: Provided herein are compositions and methods for binding outgrowth endothelial cells (OEC). The compositions consist of peptide ligands capable of binding OEC with high affinity and specificity. The compositions of the invention include peptides set forth in SEQ ID NO: 1-38 and variants and derivatives thereof. Compositions also include the nucleotide sequences encoding the peptides of the invention. The compositions find use in methods for the isolation of OEC and for the recruitment and retention of OEC to sites of therapeutic interest. Methods for the identification and isolation of other peptides capable of binding OEC are also provided.Type: GrantFiled: March 5, 2008Date of Patent: April 23, 2013Assignees: The University of North Carolina at Chapel Hill, North Carolina State University, The Ohio State University Research FoundationInventors: Cam Patterson, Anka Veleva, Stuart Cooper
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Patent number: 8428199Abstract: A transmitter and/or receiver for performing frequency domain equalization is provided. A transmitter includes a pilot position determination unit for determining positions for inserting pilots in a frequency domain based on frequency spectrums of data, and a pilot insertion unit for inserting the pilots between the frequency spectrums of the data according to the determined positions for inserting the pilots.Type: GrantFiled: October 6, 2008Date of Patent: April 23, 2013Assignees: Samsung Electronics Co., Ltd., Postech Academy-Industry FoundationInventors: Dong Sik Kim, Ui Kun Kwon, Gi Hong Im, Chang Yong Shin
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Patent number: 8426750Abstract: Provided are an electromagnetic shielding structure and a method of manufacturing the electromagnetic shielding structure. The electromagnetic shielding structure shields an electromagnetic wave having a specific frequency band, is miniaturized, and includes a strip line, and a couple of plate structures facing each other and connected to both ends of the strip line. The method of manufacturing the electromagnetic shielding structure is simple. An electromagnetic wave having a specific frequency band is shielded, and variation in electromagnetic shielding performance according to the position of an electromagnetic shielding construction is prevented, thus constructing a reliable electromagnetic shielding concrete building.Type: GrantFiled: September 17, 2009Date of Patent: April 23, 2013Assignee: Kyonggi University Industry & Academia Cooperation FoundationInventors: Hong Min Lee, Joong Kwan Kim
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Patent number: 8426630Abstract: A multi-step method for the continuous synthesis of ibuprofen or a synthetic precursor of ibuprofen is provided that does not require any intermediate purification or isolation steps and uses reagents compatible with downstream reactions. According to some embodiments, a method is provided wherein isobutylbenzene and a propionyl compound may be converted into a first product in a first Friedel Crafts acylation reaction. The first product may then be converted into a second product in a 1,2-aryl migration reaction. Finally, the second product may be converted into ibuprofen in a hydrolysis reaction. The present invention also provides a method wherein only the first and second reaction steps or only the second and third reaction steps are performed. An apparatus is also provided having two or more microreactors and two or more junctions in particular arrangements for the synthesis of ibuprofen or a synthetic precursor of ibuprofen.Type: GrantFiled: August 26, 2010Date of Patent: April 23, 2013Assignee: Florida State University Research FoundationInventors: D. Tyler McQuade, Andrew Bogdan, Sarah Lihoa Poe
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Patent number: 8428093Abstract: Semiconductor laser array devices capable of emitting mid- to long-wavelength infrared (i.e., 4-12 ?m) radiation are provided. The devices include a quantum cascade laser (QCL) structure comprising one or more active cores; an optical confinement structure; a cladding structure, and a plurality of laterally-spaced trench regions extending transversely through the cladding and optical confinement structures, and partially into the QCL structure. The trench regions define a plurality of laterally-spaced interelement regions separated by element regions in the laser array device. The element regions are characterized by a non-uniform structure across their widths. As a result of this structural non-uniformity, array modes composed of coupled first-order lateral modes of the element regions are preferentially suppressed relative to array modes composed of coupled fundamental lateral modes of the element regions.Type: GrantFiled: March 11, 2011Date of Patent: April 23, 2013Assignee: Wisconsin Alumni Research FoundationInventors: Dan Botez, Jeremy Daniel Kirch
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Patent number: 8425493Abstract: An implantable medication delivery device that is highly space efficient and can reliably and safely deliver controlled medication doses to a target site. The system includes a variable volume medication reservoir that is exposed to an ambient pressure equal to the ambient pressure at a system outlet port. A pump/valve subassembly is provided to draw medication from the reservoir and force a medication dose along a fluid transfer passageway to the outlet port. The pump/valve subassembly incorporates a safety mechanism, e.g., a balanced valve, which normally blocks medication flow to the outlet port and opens only in response to a pump induced unbalancing force. A protective shell is also disclosed for protecting the ambient reservoir.Type: GrantFiled: May 20, 2003Date of Patent: April 23, 2013Assignee: The Alfred E. Mann Foundation For Scientific ResearchInventors: Peter C. Lord, Clyde K. Nason, Darren Y. K. Yap, Stephen D. Das, Ronald J. Lebel
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Patent number: 8426935Abstract: Provided are an electronic device, a memory device, and a method of fabricating the devices for preventing physical distortion of functional elements from generating and improving electric contact properties between the functional elements and electric elements connecting to the functional elements. At least two grooves are formed in a substrate, and a conductive material is filled in the grooves to obtain electric elements having a surface at the same height as that of the substrate. In addition, a functional material layer (functional layer) is formed on an entire upper surface of the substrate and is patterned so as to obtain a functional element having both bottom surfaces contacting the electric elements.Type: GrantFiled: February 4, 2010Date of Patent: April 23, 2013Assignee: Korea University Research and Business FoundationInventors: Gyu Tae Kim, Kang Ho Lee, Hye Young Kim, Kyung Jin Lee, Woun Kang
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Patent number: 8428732Abstract: In one embodiment, a neural interface system includes an implantable neural probe having a flexible substrate, electrodes that extend from the substrate that are adapted to contact neural tissue of the brain, a signal processing circuit configured to process neural signals collected with the electrodes, and a wireless transmission circuit configured to wirelessly transmit the processed neural signals, and a backend computing device configured to wirelessly receive the processed neural signals, to process the received signals to reconstruct the collected neural signals, and to analyze the collected neural signals.Type: GrantFiled: May 22, 2009Date of Patent: April 23, 2013Assignee: University of Florida Research Foundation, Inc.Inventors: Toshikazu Nishida, John Gregory Harris, Rizwan Bashirullah, Jose Principe, Justin Sanchez
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Patent number: 8426191Abstract: The present invention provides derivatives of Escherichia coli constructed for the production of lactic acid. The transformed E. coli of the invention are prepared by deleting the genes that encode competing pathways followed by a growth-based selection for mutants with improved performance. These transformed E. coli are useful for providing an increased supply of lactic acid for use in food and industrial applications.Type: GrantFiled: December 7, 2009Date of Patent: April 23, 2013Assignee: University of Florida Research Foundation, Inc.Inventors: Shengde Zhou, Lonnie O'Neal Ingram, Keelnatham T. Shanmugam, Lorraine Yomano, Tammy B. Grabar, Jonathan C. Moore
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Publication number: 20130096692Abstract: Stents that have non-circular cross-sectional profiles and systems for delivering the stents are described herein.Type: ApplicationFiled: August 12, 2010Publication date: April 18, 2013Applicant: Mayo Foundation for Medical Education and ResearchInventors: Mark D. Topazian, Louis-Michel Wong Kee Song, Todd H. Baron, SR.
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Publication number: 20130094997Abstract: A blood oxygenator includes an integral pneumatic pump disposed substantially within a housing thereof, an inlet blood flow redirector, and an outflow blood collector. An atrium provided at an inlet of the oxygenator promotes even delivery of blood to the oxygenator. In use, the oxygenator provides an even dispersion of blood therethrough, establishing even perfusion and reducing areas of stagnant blood flow.Type: ApplicationFiled: August 13, 2012Publication date: April 18, 2013Applicant: The University of Kentucky Research FoundationInventors: Dongfang Wang, Joseph B. Zwischenberger
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Publication number: 20130094729Abstract: Apparatus or techniques can include obtaining information indicative of energy, such as ultrasonic energy, reflected from a tissue region, forming respective input matrices representative of the obtained information, the input matrices respectively comprising an ensemble-of-interest and at least one ensemble corresponding to a spatial location nearby a spatial location corresponding to the ensemble-of-interest, performing respective singular value decompositions on the respective input matrices to obtain respective sets of singular values corresponding to respective sets of singular vectors, obtaining respective output matrices including weighting a respective projection of a respective ensemble-of-interest onto at least one of the singular vectors included in a respective set of singular vectors, and, using the respective output matrices, at least one of determining a characteristic, or constructing an image, of at least a portion of the tissue region.Type: ApplicationFiled: October 12, 2012Publication date: April 18, 2013Applicant: University of Virginia Patent FoundationInventors: F. William Mauldin, JR., John A, Hossack, Abhay V. Patil
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Publication number: 20130096880Abstract: Disclosed is a test system and method that is configured to identify a position of a process control block, access the position of the process control block, and monitor performance factors related to the process control block.Type: ApplicationFiled: December 4, 2012Publication date: April 18, 2013Applicants: HYUNDAI MOTOR COMPANY, Ewha University - Industry Collaboration Foundation, KIA MOTORS CORPORATIONInventors: Hyundai Motor Company, Kia Motors Corporation, Ewha University - Industry Collaboration Foundatio
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Publication number: 20130094902Abstract: A vehicle sensing parking barricade device includes: an RFID (Radio Frequency Identification) tag which is attached to a vehicle for identifying the vehicle; a barricade bar which limits entrance of the vehicle; an RFID reader which is installed in a portion of the barricade bar and receives information from the RFID tag to determine whether or not the vehicle is authenticated to be parked; and a motor driver which receives a signal from the RFID reader 25 to drive the barricade bar 10 to limit the vehicle entrance depending on the vehicle authentication.Type: ApplicationFiled: December 29, 2011Publication date: April 18, 2013Applicant: Keimyung University Industry Academic Cooperation FoundationInventor: CHUN HO CHANG
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Publication number: 20130097391Abstract: Critical sections of multi-threaded programs, normally protected by locks providing access by only one thread, are speculatively executed concurrently by multiple threads with elision of the lock acquisition and release. Upon a completion of the speculative execution without actual conflict as may be identified using standard cache protocols, the speculative execution is committed, otherwise the speculative execution is squashed. Speculative execution with elision of the lock acquisition, allows a greater degree of parallel execution in multi-threaded programs with aggressive lock usage.Type: ApplicationFiled: November 26, 2012Publication date: April 18, 2013Applicant: Wisconsin Alumni Research FoundationInventor: Wisconsin Alumni Research Foundation
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Publication number: 20130096428Abstract: An access system and method for obtaining access to the interior vascular structures or other regions or collections of fluid or fluid-filled cavities inside the body. The system and method provides for injection of contrast agents (to confirm ideal position or condition), the passage of guide wires, and the eventual catheterization of the heart and other parts of the body via the pathway established through the puncture of a femoral artery. The system and method provides the ability to inject a contrast material and pass a guide wire through the same introducer device simultaneously (without necessarily moving it or removing any parts), with the device designed to prevent the backflow of the contrast material through the guide wire port during the contrast injection process The ideal location of access in the vein or artery can be seen by injecting contrast from a needle inside the structure and then using fluoroscopy.Type: ApplicationFiled: December 21, 2010Publication date: April 18, 2013Applicant: University of Virginia Patent FoundationInventors: George T. Gillies, Srijoy Mahapatra, D. Scott Lim, Michael Ragosta
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Publication number: 20130095042Abstract: Osteoporosis, is an exceedingly common malady that leads to bone fracture and results from an imbalance in the rate of osteoblastic bone formation with respect to osteoclastic bone degradation. Nanotechnology has raised exciting possibilities for the development of novel therapeutic agents. Embodiments of the disclosure provide silica-based fluorescent nanoparticles endowed with natural bone targeting capabilities and expressing potent pro-osteoblastogenic and concomitant anti-osteoclastogenic activities in vitro and the capacity to increase bone mineral density in vivo. Embodiments of the disclosure can achieve their stimulatory effects on osteoblasts, and inhibitory effects on osteoclasts, in part by suppressing NF-KB signal transduction. Embodiments of the present disclosure provide for derivatives of silica-based nanoparticles that represent a novel class of dual anti-catabolic and pro-anabolic agents that may be applicable to the amelioration of numerous osteoporotic conditions.Type: ApplicationFiled: November 20, 2012Publication date: April 18, 2013Applicants: Seoul National University Industry Foundation, EMORY UNIVERSITYInventors: Emory University, Seoul National University Industry Foundation
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Publication number: 20130095478Abstract: The present invention relates to htSNPs for determining a genotype of cytochrome P450 1A2 (CYP1A2), 2A6 (CYP2A6) and 2D6 (CYP2D6), PXR and UDP-glucuronosyltransferase 1a (UGT1A) genes and a gene chip using the same, and more particularly, to a selection method of htSNPs for determining a haplotype of human CYP1A2, CYP2A6, CYP2D6, PXR and UGT1A genes, a method of determining a genotype of the genes by using the htSNPs and a gene chip therefor.Type: ApplicationFiled: July 16, 2012Publication date: April 18, 2013Applicant: Inje University Industry Academic Cooperation FoundationInventors: Jae-Gook SHIN, Yin-Jin Jang, Sang-seop Lee, Hye-eun Jeong, In-june Cha, Woo-young Kim, Sung-su Yea, Eun-young Kim, Eun-young Cha, Ji-hong Shon, Eun-jeong Choi, Kang-mi Kim, Hyun-ju Jung
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Publication number: 20130097644Abstract: Provided are systems and methods of accessing a portion of a media file on a remote server. The method can comprise receiving a first uniform resource identifier associated with the media file; generating a first boundary point and a second boundary point associated with the portion of the media file, each of the first and second boundary points corresponding to a point in time between the beginning and ending points in time of the media file; generating a second uniform resource identifier configured to locate the portion of the media file between the first and the second boundary points; requesting from the remote server at least a part of the media file associated with the first uniform resource identifier; receiving at least the part of the media file from the remote server; and rendering the media file starting at the first boundary point and ending at the second boundary point.Type: ApplicationFiled: October 12, 2012Publication date: April 18, 2013Applicant: UAB Research FoundationInventor: UAB Research Foundation