Abstract: A composition can be used to treat water containing nitrogen compounds and phosphorus compounds. The composition includes iron filings, clay particles, aluminum particles, and sand particles. The iron filings, clay particles, and aluminum particles act to remove nitrogen compounds and phosphorus compounds from water. Specifically, the clay particles attract the nitrogen compounds and the phosphorus compounds to be absorbed onto a surface of the iron filings and the clay particles. The aluminum particles react with the nitrogen compounds via an oxidation reaction to form ammonia compounds and react with the phosphorus compounds to produce aluminum phosphate. The relationship between the iron filings, clay particles, and aluminum particles remove nitrogen and phosphorus compounds from water and recover the compounds in usable forms, namely, ammonia and aluminum phosphate.

Abstract: One or more techniques and/or systems are disclosed for a center frame positioning method for an agricultural sprayer. The method comprises activating a center frame positioning system and collecting and processing position data related to a position of a suspended center frame in the center frame positioning system. The method further comprises evaluating the position data to determine whether any adjustment to the position of the suspended center frame is needed and controlling actuator force in at least one actuator to adjust the position of the suspended center frame based on the evaluating the position data.

Abstract: Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.

Abstract: A method to inhibit neutrophil recruitment to damaged tissue, thereby inhibiting inflammation in a subject. The method includes administering to an anti-inflammatory amount of a myeloid-derived growth factor (“MYDGF”). Also disclosed are corresponding pharmaceutical compositions of matter containing the MYDGF.

Abstract: This specification discloses systems, methods, devices, and other techniques for determining the location of a seizure-generating region of the brain of a mammal.

Abstract: Disclosed herein are compositions and methods that involve inserting connector protein channels of bacteriophage DNA packaging motors into copolymeric membranes via liposome-polymer fusion, which can be used as nanopore sensors for biomedical applications such as high throughput protein sequencing or cancer diagnosis. For example, disclosed are compositions comprising a copolymeric membrane into which a connector protein channel of a bacteriophage packaging motor has been inserted.

Abstract: This disclosure provides methods of using BAF complex modulating compounds as inhibitors of BAF-mediated transcription in target cells. The BAF complex modulating compounds include 12-membered macrolactam compounds that can target a BAF-specific subunit (e.g., ARID1A) to prevent nucleosomal positioning, relieving transcriptional repression of HIV-1. The subject methods can provide for reversal of latency of HIV-1 in cells in vitro or in vivo. Use of the macrolactam BAF complex modulating compounds represent a method of HIV latency reversal with a unique mechanism of action, which can be optionally combined with other Latency Reversal Agents to improve reservoir targeting. The subject methods can be utilized in conjunction with any convenient methods of treating HIV or HIV latency, including methods related to immune system activation, antiretroviral therapies and/or anti-HIV agents.

Abstract: Permanent magnet materials are provided. The permanent magnet materials are cerium based materials including zirconium and iron in combination with cobalt. The permanent magnet materials may have the formula Ce2ZrFe15?xCox wherein 6?x?15. In some embodiments, the permanent magnet materials have the formula Ce2+yZr1?yFe(15?x)(2?z)/2)CoxCu((15?x)z/2) wherein 6?x?15, 0?y?0.4, and z=0 or 1. In other embodiments, the permanent magnet materials have the formula Ce2Zrx(Fe1?yCoy)17?2x, where 0<x?1 and 0.4?y?1. Permanent magnets including the permanent magnet materials are also provided.

Abstract: Systems and methods are provided that allow developers to quickly and easily develop augmented reality (AR) applications that enrich the real-world with data from the cloud. Given that the development of an AR application is a complex and time-consuming process, the systems and methods described herein allow software developers to concisely describe their needs in a succinct program, written in the QWL domain-specific language. The systems and methods take this program and automatically generate an AR application.

Abstract: This document provides methods and materials for using low coverage whole genome sequencing techniques to assess genomes. For example, methods and materials for using targeted nucleic acid amplification and/or capture techniques in combination with low coverage whole genome sequencing techniques to obtain high coverage sequencing data for one or more pre-selected regions of a genome are provided.

Abstract: The present invention relates to a cable using cold-drawn shape memory alloy wires, which facilitates concrete prestressing or other operations, and has excellent adhesion to concrete and manufacturability. The cable using cold-drawn shape memory alloy wires includes: a core wire configured by a cold-drawn shape memory alloy deformed by cold drawing to have an increased length; and a plurality of peripheral wires configured by cold-drawn shape memory alloy wires which are deformed by cold drawing to have an increased length and are couple to the core wire while being wound in a same direction along the circumference of the core wire.

Abstract: Aspects of the disclosure are directed to methods and/or apparatuses involving modifying flow and/or concentration of an agent being injected for characterizing a vascular system. As may be implemented in accordance with one or more embodiments, a liquid including an agent is injected into a vascular system, by dynamically modulating a flow rate of the agent being injected over a range of flow rates. The vascular system is characterized based on a response of the vascular system to the dynamic modulation. In some implementations, such an approach involves using an injector that operates to separately control the rate at which an agent and other liquid such as saline are injected. These approaches can be implemented with modulation schemes using one or more of a variety of functions.

Abstract: Herein reported are new tricyclic cytidine compounds, such as 8-diethylamino-tC (8-DEA-tC), that respond to DNA and/or RNA duplex formation with up to a 20-fold increase in fluorescent quantum yield as compared with the free nucleoside, depending on neighboring bases. This turn-on response to duplex formation is by far the greatest of any reported nucleoside analogue that can participate in Watson-Crick base pairing. Measurements of the quantum yield of 8-DEA-tC mispaired with adenosine and, separately, opposite an abasic site show that there is almost no fluorescence increase without the formation of correct Watson-Crick hydrogen bonds. Kinetic isotope effects from the use of deuterated buffer show that the duplex protects 8-DEA-tC against quenching by excited state proton transfer. DFT calculations provide a rationale for the observed photophysical properties that is dependent on duplex integrity and the electronic structure of the analogue.

Abstract: An autonomous system for providing consistent images of leaves of plants is disclosed which includes a mobility system configured to move from an originating position to a position above a plant in a field, a robotic system coupled to the mobility system, the robotic system includes a manipulator providing a plurality of degrees of freedom, and an imaging system having an imaging chamber and one or more cameras, the imaging system coupled to the manipulator, the manipulator and the imaging system cooperate to position the imaging system about a leaf of a plant such that the manipulator articulates the imaging chamber substantially parallel and in line with the leaf and further moves the imaging system so that the leaf enters the imaging chamber thereby allowing the imaging system to obtain images of the leaf.

Abstract: A method and an apparatus are disclosed for video coding using improved cross-component linear model (CCLM) prediction. The video coding method and the apparatus generate a first predictor of a current chroma block according to CCLM prediction, and additionally generate a second predictor of the current chroma block based on the neighboring pixels of the current chroma block in intra prediction of the current chroma block. The video coding method and the apparatus perform weighted combination on the first predictor and the second predictor.

Abstract: Disclosed is a method of operating a swap memory device configured to communicate with a host device and a main memory device. The method includes receiving, from the host device, a request corresponding to target data, determining, by the swap memory device, a first address of the target data and a second address of a target data block that includes the target data, based on the request, providing, by the swap memory device, the target data to the host device based on the first address, and providing, by the swap memory device, the target data block to the main memory device based on the second address.

Abstract: A system includes a vacuum chamber configured to enclose the material sample within, an infrared camera, a power supply, a heating stage, and a temperature controller. The infrared camera is configured to measure a temperature within the vacuum chamber and generate an output temperature value. The heating stage is coupled with a pair of electrodes, and the pair of electrodes are configured to apply a power signal to the heating stage from the power supply to affect the temperature within the vacuum chamber. The temperature controller is configured to receive the output temperature value and selectively adjust the temperature within the vacuum chamber to thereby maintain the temperature within the vacuum chamber within a desired temperature range.

Abstract: Provided herein are chimeric receptors, engineered cells and pharmaceutical compositions for enhancement of long-term clearance of protein aggregates in the central nervous system via phagocytosis or engulfment. Further provided herein are methods of treatment of subjects suffering from, or diagnosed with, a neurodegenerative disease by administering these receptors, modified cells, and/or pharmaceutical compositions. Administration of one or more, or a plurality of these modified cells, to a subject may provide treatment of a neurodegenerative disease such as Alzheimer's Disease (AD) or Parkinson's Disease (PD). Advantageously, the modified cells, pharmaceutical compositions, and methods of the present disclosure meet existing needs in the art by providing clearance of accumulations of protein aggregates in brain tissue in PD and AD pathologies.

Abstract: Provided are methods for treating and/or preventing genotoxic stress-induced cardiac toxicity, which in some embodiments include administering to a subject an effective amount of an inhibitor of t-CH, of neutrophil activation, of neutrophil migration, or any combination thereof. In some embodiments, the genotoxic stress-induced cardiac toxicity results from exposure to one or more anti-tumor and/or anti-cancer therapies, including but not limited to treatment with one or more chemotherapeutics (e.g., doxorubicin) and/or treatment with radiation. In some embodiments, the genotoxic stress-induced cardiac toxicity, the chemotherapy-induced cardiac toxicity, the chemotherapy-induced heart damage, and/or the chemotherapy-induced reduction in cardiac function is characterized by a reduction in cardiac contractility, a thinning of a ventricular wall, a reduction in cardiomyocyte size, or any combination thereof.

Abstract: A method for evaluating for the presence of the COVID disease by detecting one or more biomarkers using a breathalyzer. The breath sample taken from the subject is passed over a sensor which changes resistance in the presence of nitric oxide as a function of concentration. The resistance pattern of the subject having the COVID disease will have a distinct shape, approximating the appearance of the small Greek letter omega (?). Test results can be generated in less than a minute.