Patents Assigned to Foundation
  • Method, system and computer program product for real-time detection of sensitivity decline in analyte sensors
    Patent number: 8135548
    Abstract: A computer implemented method for receiving a plurality of analyte sensor related signals, determining a probability of signal attenuation associated with the received plurality of analyte sensor related signals, verifying the presence of signal attenuation when the determined probability exceeds a predetermined threshold level, and generating a first output signal associated with the verification of the presence of signal attenuation is provided. Also provided are systems and kits.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: March 13, 2012
    Assignees: Abbott Diabetes Care Inc., University of Virginia Patent Foundation
    Inventors: Marc D. Breton, Boris P. Kovatchev, Erwin S. Budiman, Kenneth J. Doniger
  • Method and system for image reconstruction
    Patent number: 8135186
    Abstract: Disclosed is an imaging system including a source generating an x-ray beam, a detector array receiving the x-ray beam and generating projection data, a translatable table configured for disposal of an object thereon and operable to translate in relation to the source and the detector array, the source and the detector array rotating about the translatable table to scan the object, and an image reconstructor electrically coupled to the detector array and configured to reconstruct an image in response to the projection data via an iterative reconstruction technique configured to perform a targeted statistical reconstruction.
    Type: Grant
    Filed: January 25, 2008
    Date of Patent: March 13, 2012
    Assignees: Purdue Research Foundation, General Electric Company, University of Notre Dame Du Lac
    Inventors: Charles A. Bouman, Ken David Sauer, Jean-Baptiste Thibault, Zhou Yu
  • Lanthanum oxide-doped glass-ceramics
    Patent number: 8133828
    Abstract: Glass-ceramic compositions exhibiting high reliability and tensile strength are described. The compositions can include crystal phases including roedderite and/or potassium fluorrichterite. The glass-ceramic compositions are bioactive, and can be used as components of a wide variety of biomedical devices such as dental restorations.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: March 13, 2012
    Assignee: The Ohio State University Research Foundation
    Inventors: Isabelle L. Denry, Julie A. Holloway
  • RFID system preventing recognition error and communication method thereof
    Patent number: 8134466
    Abstract: A radio frequency identification (RFID) tag is provided that prevents a recognition error of the RFID tag due to the occurrence of a shadow region. The RFID tag includes a first tag performing communication with an RFID reader and a second tag connected to the first tag and suitable for use with a different communication type from the first tag. Thus, when information stored in the first tag can not be read, the second tag is activated and externally transmits information and when information stored in the first tag can be read, the second tag is deactivated and does not externally transmit information. A communication method of an RFID system including an RFID reader communicating with an RFID tag is also provided.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: March 13, 2012
    Assignees: Samsung Techwin Co., Ltd., Industry-University Cooperation Foundation Hanyang Universtiy
    Inventors: Ki-yong Jeon, Sung-ho Cho
  • Method and apparatus for estimating noise by using harmonics of voice signal
    Patent number: 8135586
    Abstract: Disclosed is a method and an apparatus for estimating noise included in a sound signal during sound signal processing. The method includes estimating harmonics components in a frame of an input sound signal; using the estimated harmonics components, computing a Voice Presence Probability (VPP) on the frame of the input sound signal; determining a weight of an equation necessary to estimate a noise spectrum, depending on the computed VPP; and using the determined weight and the equation necessary to estimate a noise spectrum, estimating the noise spectrum, and updating the noise spectrum.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: March 13, 2012
    Assignees: Samsung Electronics Co., Ltd, Korea University Industrial & Academic Collaboration Foundation
    Inventors: Hyun-Soo Kim, Hanseok Ko, Sung-Joo Ahn, Jounghoon Beh, Hyun-Jin Yoon
  • Liquid crystal display panel with improved display characteristics and mask used to fabricate the same
    Patent number: 8134678
    Abstract: A liquid crystal display (LCD) panel with improved display characteristics includes a first display plate and a second display plate which face each other with a liquid crystal layer therebetween, a seal bonding the first display plate to the second display plate to prevent leakage of the liquid crystal layer, and an impurity blocking and liquid crystal flowing structure disposed inside a perimeter of the seal to prevent impurities from flowing from the seal to an active region in the first and second display plates while providing a flow path allowing liquid crystals to flow to the seal.
    Type: Grant
    Filed: October 4, 2006
    Date of Patent: March 13, 2012
    Assignees: Samsung Electronics Co., Ltd., Seoul National University Industry Foundation
    Inventors: Yoon-jang Kim, Dong-jin Seo, Yun-seok Lee, Cheon-jae Maeng, Ji-hyeon Son, Jae-yong Shin
  • Method of forming myeloid precursor cells from human embryonic stem cells
    Patent number: 8133732
    Abstract: This invention relates to the culture of dendritic cells from human embryonic stem (ES) cells. Human ES cells are first cultured into hematopoietic cells by co-culture with stromal cells. The cells now differentiated into the hematopoietic lineage are then cultured with GM-CSF to create a culture of myeloid precursor cells. Culture of the myeloid precursor cells with the cytokines GM-CSF and IL-4 causes functional dendritic cells to be generated. The dendritic cells have a unique phenotype, as indicated by their combination of cell surface markers.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: March 13, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Igor I. Slukvin, James A. Thomson, Maksym A. Vodyanyk, Maryna E. Gumenyuk
  • Short-channel silicon carbide power mosfet
    Patent number: 8133789
    Abstract: A silicon carbide power MOSFET having a drain region of a first conductivity type, a base region of a second conductivity type above the drain region, and a source region of the first conductivity type adjacent an upper surface of the base region, the base region including a channel extending from the source region through the base region adjacent a gate interface surface thereof, the channel having a length less than approximately 0.6 ?m, and the base region having a doping concentration of the second conductivity type sufficiently high that the potential barrier at the source end of the channel is not lowered by the voltage applied to the drain. The MOSFET includes self-aligned base and source regions as well as self-aligned ohmic contacts to the base and source regions.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: March 13, 2012
    Assignee: Purdue Research Foundation
    Inventors: James A. Cooper, Maherin Matin
  • Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds
    Patent number: 8133515
    Abstract: 1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: March 13, 2012
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Geert-Jan Boons, Jun Guo, Xinghai Ning, Margaretha Wolfert
  • Hidden markov model (“HMM”)-based user authentication using keystroke dynamics
    Patent number: 8136154
    Abstract: Hidden Markov Models (“HMMs”) are used to analyze keystroke dynamics measurements collected as a user types a predetermined string on a keyboard. A user enrolls by typing the predetermined string several times; the enrollment samples are used to train a HMM to identify the user. A candidate who claims to be the user provides a typing sample, and the HMM produces a probability to estimate the likelihood that the candidate is the user he claims to be. A computationally-efficient method for preparing HMMs to analyze certain types of processes is also described.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: March 13, 2012
    Assignees: The Penn State Foundation, Louisiana Tech Unversity Research Foundation
    Inventors: Vir V. Phoha, Shashi Phoha, Asok Ray, Shrijit Sudhakar Joshi, Sampath Kumar Vuyyuru
  • Methods and compositions for forming patterns with isolated or discrete features using block copolymer materials
    Patent number: 8133534
    Abstract: Methods of directing the self assembly of block copolymers on chemically patterned surfaces to pattern discrete or isolated features needed for applications including patterning integrated circuit layouts are described. According to various embodiments, these features include lines, t-junctions, bends, spots and jogs. In certain embodiments a uniform field surrounds the discrete feature or features. In certain embodiments, a layer contains two or more distinct regions, the regions differing in one or more of type of feature, size, and/or pitch. An example is an isolated spot at one area of the substrate, and a t-junction at another area of the substrate. These features or regions of features may be separated by unpatterned or uniform fields, or may be adjacent to one another. Applications include masks for nanoscale pattern transfer as well as the fabrication of integrated circuit device structures.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: March 13, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark P. Stoykovich, Huiman Kang, Konstantinos C. Daoulas, Juan J. de Pablo, Marcus Muller, Paul Franklin Nealey
  • Use of nicotinic acid adenine dinucleotide phosphate or derivative thereof as agent for treating type-2 diabetes
    Patent number: 8133872
    Abstract: The administration of nicotinic acid adenine dinucleotide phosphate (NAADP) or a pharmaceutically acceptable salt thereof to a host in need thereof for the treatment of type-2 diabetes has been disclosed.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: March 13, 2012
    Assignee: Industrial Cooperation Foundation, Chonbuk National University
    Inventors: Uh Hyun Kim, Kwang Hyun Park, Myung Kwan Han
  • Colorimetric detection of uranium in water
    Patent number: 8133740
    Abstract: Disclosed are methods, materials and systems that can be used to determine qualitatively or quantitatively the level of uranium contamination in water samples. Beneficially, disclosed systems are relatively simple and cost-effective. For example, disclosed systems can be utilized by consumers having little or no training in chemical analysis techniques. Methods generally include a concentration step and a complexation step. Uranium concentration can be carried out according to an extraction chromatographic process and complexation can chemically bind uranium with a detectable substance such that the formed substance is visually detectable. Methods can detect uranium contamination down to levels even below the MCL as established by the EPA.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: March 13, 2012
    Assignees: Clemson University Research Foundation, Savannah River Nuclear Solutions, LLC
    Inventors: Timothy A. DeVol, Amy E. Hixon, David P. DiPrete
  • INFLUENZA VIRUS-NEUTRALIZING ANTIBODY AND SCREENING METHOD THEREFOR
    Publication number: 20120058124
    Abstract: Provided is an anti-influenza virus antibody that exhibits neutralizing activity beyond the barrier of the two groups of influenza viruses categorized according to the conservativeness of hemagglutinin amino acids, a method of producing the same, and a test method for determining whether the subject carries the neutralizing antibody.
    Type: Application
    Filed: August 4, 2011
    Publication date: March 8, 2012
    Applicants: The Research Foundation for Microbial Diseases of Osaka University, FUJITA HEALTH UNIVERSITY
    Inventors: Yoshikazu KUROSAWA, Yoshitaka IBA, Nobuko OHSHIMA, Yoshinobu OKUNO
  • METHOD OF USING AN ANTI-CD137 ANTIBODY AS AN AGENT FOR RADIOIMMUNOTHERAPY OR RADIOIMMUNODETECTION
    Publication number: 20120058047
    Abstract: The current invention relates to the development and methods of use of a recombinant agonistic antibody anti-human CD137, and glycosylation variants thereof. These antibodies act as anti-cancer agents and/or immune modulators that are effective in shrinking solid tumors or other cancerous indications and preventing their recurrence. The types of cancer for which the contemplated antibody is effective in treating also include leukemia and lymphoma. In a preferred embodiment the recombinant antibodies of the current invention were produced in and purified from the milk of transgenic animals. In another preferred embodiment of the current invention the agonistic anti-CD137 antibodies of the invention can be conjugated to radionuclides for radioimmunodetection or radioimmunotherapeutic purposes, or conjugated to a toxin for enhanced therapeutic treatment of various cancers.
    Type: Application
    Filed: February 26, 2010
    Publication date: March 8, 2012
    Applicants: Mayo Foundation for Medical Education and Research, GTC Biotherapeutics, Inc.
    Inventors: Scott E. Strome, Daniel Schindler, Lieping Chen, Harry M. Meade, Yann Echelard
  • EXPANDABLE SPACE-OCCUPYING TISSUE RETRACTORS
    Publication number: 20120059225
    Abstract: This document provides methods and materials for retracting tissue during a minimally invasive surgical procedure (e.g., an endoscopic surgical procedure). For example, methods and materials for using an expandable space-occupying tissue retractor during an endoscopic surgical procedure such as a laparoscopic cholecystectomy procedure or a NOTES procedure are provided.
    Type: Application
    Filed: September 1, 2011
    Publication date: March 8, 2012
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Christopher J. Gostout, Juliane Bingener-Casey, Eduardo Aimore Bonin
  • SYNTHETIC PEPTIDES AND PEPTIDE MIMETICS
    Publication number: 20120058933
    Abstract: The present invention provides Parotid Secretory Protein peptides, nucleic acids encoding the peptides, and methods of using the peptides, and methods of screening GL13 mimetics.
    Type: Application
    Filed: May 8, 2008
    Publication date: March 8, 2012
    Applicant: University of Louisville Research Foundation
    Inventor: Sven-Ulrik Gorr
  • ALKYLATED SEMI SYNTHETIC GLYCOSAMINOGLYCOSAN ETHERS, AND METHODS FOR MAKING AND USING THEREOF
    Publication number: 20120058161
    Abstract: Described herein are alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated and alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including use for ocular or ophthalmic treatment.
    Type: Application
    Filed: November 23, 2011
    Publication date: March 8, 2012
    Applicant: University of Utah Research Foundation
    Inventors: Glenn D. Prestwich, Jianxing Zhang, Thomas P. Kennedy, Narayanam V. Rao
  • STABILIZED BIOACTIVE PEPTIDES AND METHODS OF IDENTIFICATION, SYNTHESIS, AND USE
    Publication number: 20120059145
    Abstract: An intracellular selection system allows screening for peptide bioactivity and stability. Randomized recombinant peptides are screened for bioactivity in a tightly regulated expression system, preferably derived from the wild-type lac operon. Bioactive peptides thus identified are inherently protease- and peptidase-resistant. Also provided are bioactive peptides stabilized by a stabilizing group at the N-terminus, the C-terminus, or both. The stabilizing group can be a small stable protein, such as the Rop protein, glutathione sulfotransferase, thioredoxin, maltose binding protein, or glutathione reductase, an ?-helical moiety, or one or more proline residues.
    Type: Application
    Filed: August 31, 2011
    Publication date: March 8, 2012
    Applicant: University of Georgia Research Foundation, Inc.
    Inventor: Elliot ALTMAN
  • DETECTION OF BIOTARGETS USING BIORECEPTOR FUNCTIONALIZED NANOPARTICLES
    Publication number: 20120058548
    Abstract: A system for determining a presence of biomolecule targets includes a vessel holding a sample solution suspected of containing the biomolecule targets and a plurality of probes including bioreceptor functionalized metal nanoparticles including a plurality of metal atoms. The biomolecule targets when present in the sample solution bind to the plurality of probes. A separation device is for separating the plurality of probes into a first group of probes having the biomolecule targets bound thereto and a second group of probes not having the biomolecule targets bound thereto. A reagent is introduced via a port for breaking down the metal nanoparticles in the first group or second group of probes, wherein at least one signal moiety solution is formed. A device measures a parameter of the signal moiety solution.
    Type: Application
    Filed: September 6, 2011
    Publication date: March 8, 2012
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: QUN HUO, XIONG LIU, QIU DAI