Patents Assigned to Foundation
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Patent number: 8124110Abstract: The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and their use in diagnostic, therapeutic and vaccine applications. According to the present invention, the isolated molecules encoding for BigL1, BigL2 and BigL3 proteins are used for the diagnosis and prevention of infection with Leptospira species that are capable of producing disease in humans and other mammals, including those of veterinary importance.Type: GrantFiled: August 23, 2011Date of Patent: February 28, 2012Assignees: The United States of America as represented by the Department of Veterans Affairs, The Regents of the University of California, Cornell Research Foundation, Inc., Fundação Oswaldo Cruz - FIOCRUZInventors: Albert I. Ko, Mitermayer Galvão Reis, Julio Henrique Rosa Croda, Isadora Cristina Siqueira, David A. Haake, James Matsunaga, Lee W. Riley, Michele Barocchi, Tracy Ann Young
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Patent number: 8123564Abstract: An apparatus for connecting a computing device to different types of mobile devices that includes an enclosure that encloses a USB hub, mobile device cables connectable to different mobile devices, and a USB cable connectable to a computing device to extract data from connected mobile devices. The mobile device cables are coupled to the USB cable through the USB hub. The apparatus can include multimedia card readers within the enclosure that are coupled to the USB hub and connectable to different types of multimedia cards to extract data from connected multimedia cards. The multimedia card readers can be write-protected to only read information from connected multimedia cards. The apparatus can include biometric data gathering tools, camera or light within the enclosure. The enclosure can be tube, notebook or flask shaped. The apparatus can also include a wiring harness that seals one end of the enclosure from the other end.Type: GrantFiled: February 15, 2011Date of Patent: February 28, 2012Assignees: Purdue Research Foundation, Battlefield Telecommunications Systems, LLCInventors: Richard P. Mislan, Sean Lane
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Patent number: 8124832Abstract: Provided is a method for producing a cloned dog by enucleating an oocyte of a dog to produce an enucleated oocyte, transferring a somatic cell of the dog into the enucleated oocyte, carrying out electrofusion under optimized conditions to produce a nuclear transfer embryo, and transferring the nuclear transfer embryo into its surrogate mother.Type: GrantFiled: June 13, 2007Date of Patent: February 28, 2012Assignee: Seoul National University Industry FoundationInventors: Byeong Chun Lee, Sung Keun Kang, Dae Yong Kim, Min Kyu Kim, Goo Jang, Hyun Ju Oh, M. Shamim Hossein, Fibrianto Yuda, Hye Jin Kim, So Gun Hong, Jung Eun Park, Joung Joo Kim
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Patent number: 8124298Abstract: Provided are a metallic separator for fuel cell in which a Cr2N layer is formed on the surface of base metals, and a method of fabricating the metallic separator or fuel cell. The method comprises: plating chromium layer on the surface of the base metal; and forming a Cr2N layer by nitriding the chromium-plated layer in properly selected nitriding conditions. Only the Cr2N layer, which has lower electrical resistivity than CrN, is selectively fabricated on the surface of the base metal. The interfacial contact resistance of the separator is reduced and the efficiency of the fuel cell can be improved. In addition, since a low-priced general metals or alloys such as stainless steels, carbon steels, alloy steels or even nonferrous alloys can be used as the base metal, the cost of the fabrication of metallic separator can be significantly reduced. The thickness of the separator can be made as small as to 0.2 mm, the weight and total thickness of a fuel cell stack can be significantly reduced.Type: GrantFiled: December 7, 2006Date of Patent: February 28, 2012Assignee: Seoul National University Industry FoundationInventors: Dae Geun Nam, Hu Chul Lee
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Patent number: 8127357Abstract: A method of predicting a SYN flooding attack on a server. The method tracks the number of SYN signals received (or SYN+ACK signals sent) over the communications port of the server in a specified time interval, the arrival estimation window. The invention then predicts the number of anticipated ACK, RST or ACK+RST signals to be received over the communication port within a predetermined time length prediction window. The prediction may be made at multiple points within the prediction window. The prediction window is offset in time from the arrival estimation window. The prediction of ACK signals to be received is based upon the number of SYN signals received or SYN+ACK signals sent in the arrival estimation window. In one embodiment, a polynomial is fit to the data in the Arrival estimation window and extrapolated to the prediction window.Type: GrantFiled: November 30, 2010Date of Patent: February 28, 2012Assignee: Louisiana Tech Research Foundation; A Division of Louisiana Tech University Foundation, Inc.Inventors: Vir V Phoha, Kiran S Balagani
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Patent number: 8124178Abstract: A directed vapor deposition (DVD) method and system for applying at least one bond coating on at least one substrate for thermal barrier coating systems. To overcome the limitations incurred by conventional methods, the DVD system uses an electron beam directed vapor deposition (DVD) technique to evaporate and deposit compositionally and morphologically controlled bond coats at high rate. The present DVD system uses the combination of an electron beam and a combined inert gas/reactive gas carrier jet of controlled composition to create engineering films. In this system, the vaporized material can be entrained in the carrier gas jet and deposited onto the substrate at a high rate and with high materials utilization efficiency. The velocity and flux of the gas atoms entering the chamber, the nozzle parameters, and the operating chamber pressure can all be significantly varied, facilitating wide processing condition variation and allowing for improved control over the properties of the deposited layer.Type: GrantFiled: September 10, 2002Date of Patent: February 28, 2012Assignee: University of Virginia Patent FoundationInventors: Derek D. Hass, Haydn N. G. Wadley, Kumar P. Dharmasena, Yosef Marciano
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Patent number: 8125640Abstract: The present invention provides systems and methods for data acquisition and image analysis that utilize twisted nematic liquid crystals (“TNLCs”) to create maps of bio/chemical functionality patterned on surfaces. The method involves the acquisition of a series of images of TNLC film that contacts the analytic surface followed by analysis of the series of images to yield maps of twist angle of the liquid crystal across the surface. This analysis technique effectively condenses a large data set (stack of images) into a compact form (map of twist angle), revealing features on the surface that were not apparent in the individual images comprising the original stack.Type: GrantFiled: March 3, 2009Date of Patent: February 28, 2012Assignee: Wisconsin Alumni Research FoundationInventors: Nicholas L. Abbott, Aaron M. Lowe
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Patent number: 8124518Abstract: Nanowire devices comprising core-shell or segmented nanowires are provided. In these nanowire devices, strain can be used as a tool to form metallic portions in nanowires made from compound semiconductor materials, and/or to create nanowires in which embedded quantum dots experience negative hydrostatic pressure or high positive hydrostatic pressure, whereby a phase transitions may occur, and/or to create exciton crystals.Type: GrantFiled: May 9, 2011Date of Patent: February 28, 2012Assignee: University of Iowa Research FoundationInventors: Craig Pryor, Mats-Erik Pistol
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Patent number: 8123904Abstract: The present invention provides a method for producing an MDF board from pulp from a fibrous lignocellulose material using a treatment or pretreatment step which exposes the material to oxalic acid or oxalic acid derivatives (particularly dialkyl ester derivatives, particularly in the vapor phase). The treated wood is then subjected to a sugar extraction wash and refined using any one of the several pulping methods to produce a final pulp product. Once this is done the pulp is used to make MDF boards having improved water repellency properties.Type: GrantFiled: August 11, 2010Date of Patent: February 28, 2012Assignees: Wisconsin Alumni Research Foundation, Biopulping International Inc., The United States of America as represented by the Secretary of AgricultureInventors: Masood Akhtar, William R. Kenealy, Eric G. Horn, Ross E. Swaney, Jerrold Winandy
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Patent number: 8124358Abstract: Disclosed herein are methods of diagnosing, preventing and treating Alzheimer's disease based on the use of an inhibitor for the binding of amyloid-? (A?) to Fc?RIIb, and a method of screening the inhibitor. The inhibitor is selected from the group consisting of an Fc?RIIb protein or a variant thereof, an Fc?RIIb extracellular domain, an anti-Fc?RIIb antibody, an Fc?RIIb-specific peptide and an Fc?RIIb-specific siRNA. The inhibitor reduces the toxic signaling and intracellular translocation of A? and the neurotoxicity, neuronal cell death and memory impairment mediated by A? by inhibiting the binding between A? and Fc?RIIb. Thus, the inhibitor is useful in the diagnosis, prevention and treatment of Alzheimer's disease.Type: GrantFiled: November 29, 2007Date of Patent: February 28, 2012Assignee: Seoul National University Industry FoundationInventors: Yong-Keun Jung, Sungmin Song
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Patent number: 8124259Abstract: A microbial fuel cell (100) includes an anode compartment (110) including an anode (115) and anolyte (120). The anolyte (120) comprises a plurality of in-vivo cells (125) mixed with a plurality of electrically conducting nano or micro-scale fibers (128), wherein at least a portion of the plurality of electrically conducting fibers (128) are in electrical contact with a surface of the anode (115). A cathode compartment (140) includes a cathode (145) and a catholyte (150). A cation-exchange membrane (155) is disposed between the anode compartment (110) and the cathode compartment (140).Type: GrantFiled: October 20, 2005Date of Patent: February 28, 2012Assignee: University of Florida Research Foundation, Inc.Inventors: Andrew G. Rinzler, Lonnie O'Neal Ingram, Keelnatham T. Shanmugam, Jonathan C. Moore, Zhuangchun Wu
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Patent number: 8124979Abstract: Provided are a thin film transistor and a method of manufacturing the same. The thin film transistor includes: a lower structure; a semiconductor layer formed on the lower structure and including a plurality of doping regions; a first insulating layer and a second insulating layer formed on the semiconductor layer and separated from each other; a third insulating layer formed on the first insulating layer and the second insulating layer; and a gate electrode layer formed between regions of the third insulating layer respectively corresponding to the first insulating layer and the second insulating layer.Type: GrantFiled: February 15, 2008Date of Patent: February 28, 2012Assignees: Samsung Electronics Co., Ltd., Seoul National University Industry FoundationInventors: Ji-sim Jung, Myung-kwan Ryu, Jang-yeon Kwon, Kyung-bae Park, Min-koo Han, Sang-yoon Lee, Joong-hyun Park, Sang-myeon Han, Sun-jae Kim
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Patent number: 8124342Abstract: A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is treated with a high fidelity polymerase to permit the replication and amplification of the target nucleic acid sequence. In preferred embodiments, the polymerase comprises a polymerase holoenzyme. In further preferred embodiments, the recombination factor is bacteriophage T4 UvsX protein or homologs from other species, and the polymerase holoenzyme comprises a polymerase enzyme, a clamp protein and a clamp loader protein, derived from viral, bacteriophage, prokaryotic, archaebacterial, or eukaryotic systems.Type: GrantFiled: May 24, 2010Date of Patent: February 28, 2012Assignee: The Pann State Research FoundationInventors: Stephen J. Benkovic, Frank Salinas
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Patent number: 8122757Abstract: A propellant ignition testing apparatus having a compressively sealable chamber. A fixed end plate assembly is fixedly mounted on a support structure. A test chamber assembly having a combustion chamber for accommodating propellant is provided, and an initiator ignites propellant accommodated in the combustion chamber. A moveable end plate is disposed adjacent to the test chamber assembly on a side thereof remote from the fixed end plate assembly. A device is mounted on the support structure for generating a compressive force, with the moveable end plate being operatively connected to a moveable component of the device for moving the moveable end plate toward the test chamber assembly for sandwiching the combustion chamber of the test chamber assembly in a compressively sealed manner between the fixed end plate assembly and the moveable end plate.Type: GrantFiled: March 20, 2009Date of Patent: February 28, 2012Assignee: New Mexico Technical Research FoundationInventors: Clay Thompson, Huseyin Koksal, Jesse Piotrowicz, Alex Myers, Daniel Kitts, Joshua T. Fleming, David M. Baker, Ian Montano
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Patent number: 8123922Abstract: Nanopore based ion-selective electrodes and methods of their manufacture as well as methods for their use are disclosed and described. The nanopore based ion-selective electrode can include a pore being present in a solid material and having a nanosize opening in the solid material, a metal conductor disposed inside the pore opposite the opening in the solid material, a reference electrode material contacting said metal conductor and disposed inside the pore, a conductive composition in contact with the reference electrode and disposed in the pore, and an ion-selective membrane. The ion-selective membrane can be configured to isolate the metal conductor, reference electrode material, and conductive composition together within the pore.Type: GrantFiled: September 7, 2007Date of Patent: February 28, 2012Assignee: University of Utah Research FoundationInventors: Henry S. White, Ryan J. White, Richard B. Brown, Hakhyun Nam, Jun Ho Shim
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Patent number: 8124851Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products.Type: GrantFiled: November 12, 2008Date of Patent: February 28, 2012Assignees: North Carolina State University, University of Kentucky Research FoundationInventors: Ralph E. Dewey, Balazs Siminszky, Steven W. Bowen, Lily Gavilano
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Patent number: 8122883Abstract: Embodiments of the present invention described and shown in the specification and drawings include a system and method for monitoring the ventilation support provided by a ventilator and automatically supplying a breathing gas to a patient via a breathing circuit that is in fluid communication with the lungs of the patient.Type: GrantFiled: January 17, 2006Date of Patent: February 28, 2012Assignee: University of Florida Research Foundation, Inc.Inventors: Michael J. Banner, Paul B. Blanch, Neil R. Euliano, Jose C. Principe
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Patent number: 8124767Abstract: Disclosed are a luminescence biotin-transition metal complex conjugate and a method of amplifying signals using the same. More particularly, disclosed herein are a luminescence biotin-transition metal complex conjugate comprising an energy acceptor and biotin, and optionally an energy donor and a method of amplifying signals using the biotin-transition metal complex conjugate using intramolecular energy transfer. The luminescence biotin-transition metal complex conjugate using a transition metal probe provides a phosphorescence detection system capable of improved sensitivity.Type: GrantFiled: February 12, 2009Date of Patent: February 28, 2012Assignees: Samsung Electronics Co., Ltd., Seoul National Univeristy Industry FoundationInventors: Tae-hyuk Kwon, Jong-chul Kwon, Jong-in Hong
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Patent number: 8124771Abstract: Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.Type: GrantFiled: May 19, 2009Date of Patent: February 28, 2012Assignee: University of Tennessee Research FoundationInventors: Bob M. Moore, II, Steven Gurley, Suni Mustafa
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Patent number: 8124171Abstract: A method of manufacturing a tape-formed oxide superconductor, in which a tape-formed wire material (6 in FIG. 1) is extended between a pair of reels (5a and 5b). Besides, a reactive gas is supplied form the gas supply ports of a reactive gas supply pipe (3a) vertically to the upper side film surface of the tape-formed wire material (6), so as to react the film body of this tape-formed wire material into a superconducting layer, while at the same time, a gas after the reaction is discharged from the gas discharge ports of discharge pipes (4a and 4b) for discharging the gas after the reaction. Likewise, the reactive gas is supplied vertically to the lower side film surface of the tape-formed wire material (6), so as to react the film body of this tape-formed wire material into a superconducting layer, while at the same time, the gas after the reaction is discharged from the gas discharge ports of discharge pipes (4c and 4d) for discharging the gas after the reaction.Type: GrantFiled: March 22, 2006Date of Patent: February 28, 2012Assignees: International Superconductivity Technology Center, The Juridical Foundation, SWCC Showa Cable Systems Co., Ltd.Inventors: Yuji Aoki, Hiroshi Fuji, Sukeharu Nomoto, Ryo Teranishi, Teruo Izumi, Yuh Shiohara