Patents Assigned to Foundation
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Publication number: 20110256164Abstract: Provided are methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER/neu oncogene, GP2, with the effect of inducing and maintaining protective or therapeutic immunity against breast cancer in a patient in clinical remission, including patients having low to intermediate levels of HER2/neu expression. The methods comprise administering to the patient an effective amount of a vaccine composition comprising a pharmaceutically acceptable carrier, an adjuvant such as GM-CSF, and the GP2 peptide. The methods may further comprise administering a periodic booster vaccine dose as needed due to declining GP2-specific T cell immunity. Also provided are vaccine compositions for use in the methods.Type: ApplicationFiled: December 9, 2009Publication date: October 20, 2011Applicant: The Henry M. Jackson Foundation for the Advancemen t of Military Medicine, Inc.Inventors: George Peoples, Sathibalan Ponniah
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Publication number: 20110256112Abstract: A method of increasing the velocity of AV conduction in a mammal that may be in heart block or at risk of heart block by causing, in an AV node and/or His bundle having less than normal conduction speed, the expression of a sodium channel or gap junction protein, such as the SkM-1 channel, Cx43 or Cx32, so as to increase the velocity of conduction by the AV node.Type: ApplicationFiled: March 6, 2009Publication date: October 20, 2011Applicants: The Trustees Of Columbia University In The City Of New York, The Research Foundation of State University of New YorkInventors: Ira Cohen, Peter Brink, Michael Rosen, Richard Robinson
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Publication number: 20110253330Abstract: Flame retardant composite materials are provided which include at least one first paper which comprises carbon nanofibers and graphite oxide particles. The composite materials may further include at least one second paper which comprises carbon nanofibers. The composites may further include one or more structural material layers sandwiched between the first and second papers. Occupant structures are also provided with fire and smoke retardant surfaces composed of carbon nanofibers/graphite oxide particles papers at least partially surrounding occupants of the occupant structures.Type: ApplicationFiled: April 18, 2011Publication date: October 20, 2011Applicant: Florida State University Research Foundation, Inc.Inventors: Chuck Zhang, Zhiyong Liang, Ben Wang, Qiang Wu
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Publication number: 20110253535Abstract: Provided is a multi-channel apparatus for non-gel based two-dimensional protein separation. One or more flat channels are arranged in parallel and have an isoelectric focusing section for primarily separating proteins from protein samples according to isoelectric point (pI) and a flow field-flow fractionation section for secondarily separating the primarily separated proteins according to molecular weight, thereby making it possible to simultaneously separate the proteins in multiple channels, to increase a protein separation speed, and to overcome limitation to sample injection due to an increase in channel volume. The apparatus can separate the proteins according to pI and molecular weight, be safe from denaturation of the protein in the process of protein separation, automatically remove an ampholyte used for pI-based separation, and separately detecting the separated proteins to identify the proteins using nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS-MS).Type: ApplicationFiled: May 25, 2009Publication date: October 20, 2011Applicant: Yonsei University - Industry Academic Cooperation FoundationInventors: Myeong Hee Moon, Ki Hun Kim
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Publication number: 20110255307Abstract: There are provided an apparatus and a method for controlling the power quality of a power generation system. According to the present invention, there is provided an apparatus for controlling the power quality of a power generation system including a DC/AC inverter converting DC voltage into AC voltage and supplying inverter current to a grid, including: a grid voltage phase follower generating a grid signal; a fundamental extractor extracting a magnitude of a fundamental wave of a load current introduced into a non-linear load connected between the DC/AC inverter and the grid; a first calculator subtracting a preset current compensation value from the magnitude of the fundamental wave from the fundamental extractor; and a second calculator generating an inverter current instruction value for the DC/AC inverter by using the output value of the first calculator and the grid signal and the load current from the grid voltage phase follower.Type: ApplicationFiled: October 18, 2010Publication date: October 20, 2011Applicants: SUNGKYUNKWAN UNIVERSITY Foundation for Corporate Collaboration, SAMSUNG ELECTRO-MECHANICS CO., LTD.Inventors: Tae Hoon KIM, Jae Hyung KIM, Jun Gu KIM, Yong Hyok JI, Chung Yuen WON, Doo Young SONG, Byoung Kuk LEE, Dong Seong OH, Tae Won LEE, Jin Wook KIM
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Publication number: 20110257981Abstract: Disclosed is an LPC residual signal encoding/decoding apparatus of an MDCT based unified voice and audio encoding device. The LPC residual signal encoding apparatus analyzes a property of an input signal, selects an encoding method of an LPC filtered signal, and encode the LPC residual signal based on one of a real filterbank, a complex filterbank, and an algebraic code excited linear prediction (ACELP).Type: ApplicationFiled: October 13, 2009Publication date: October 20, 2011Applicants: Kwangwoon University Industry-Academic Collaboration Foundation, Electronics and Telecommunications Research InstituteInventors: Seung Kwon Beack, Tae Jin Lee, Min Je Kim, Kyeongok Kang, Dae Young Jang, Jin Woo Hong, Jeongil Seo, Chieteuk Ahn, Hochong Park, Young-cheol Park
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Patent number: 8038849Abstract: A process for producing a carbon-particle structure, including the step of irradiating opaque carbon dioxide at and/or near its critical point, as light is scattered, with a UV-wavelength laser beam to produce a carbon-particle structure.Type: GrantFiled: May 12, 2009Date of Patent: October 18, 2011Assignee: Toyo University Educational FoundationInventors: Toru Maekawa, Yoshikazu Yoshida, Takahiro Fukuda
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Patent number: 8039243Abstract: The present invention provides a bacterium having a genome that is genetically engineered to be smaller than the genome of its native parent strain. A bacterium with a smaller genome can produce a commercial product more efficiently. The present invention also provides methods for deleting genes and other DNA sequences from a bacterial genome. The methods provide precise deletions and seldom introduces mutations to the genomic DNA sequences around the deletion sites. Thus, the methods can be used to generate a series of deletions in a bacterium without increasing the possibility of undesired homologous recombination within the genome. In addition, some of the methods provided by the present invention can also be used for replacing a region of a bacterial genome with a desired DNA sequence.Type: GrantFiled: December 9, 2005Date of Patent: October 18, 2011Assignee: Wisconsin Alumni Research FoundationInventor: Frederick R. Blattner
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Patent number: 8038907Abstract: Novel, simple methods are presented directed to the synthesis of aligned nanofibers of polyaniline and substituted derivatives on a substrate. The production of these fibers is achieved via various methods by controlling the concentration of aniline monomer or substituted aniline derivatives or an oxidant in the reaction medium and maintaining said concentration at a level much lower than conventional polyaniline synthesis methods. Methods are disclosed relating to the use of a permeable membrane to control the release of a monomer and/or oxidant as well as a bulk polymerization method.Type: GrantFiled: April 2, 2007Date of Patent: October 18, 2011Assignee: The Ohio State University Research FoundationInventors: Arthur J. Epstein, Nan-Rong Chiou, Ly James Lee, Chunmeng Lu
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Patent number: 8041420Abstract: Apparatus for measuring the electrical impedance of a tissue sample comprises a probe and a sheath comprising an elongated tubular body having one closed end and one open end providing an internal cavity. The sheath is composed of a material which when contacted with a tissue sample is capable of providing a conductive path through the sheath between the electrodes and the tissue sample. The resistivity of the material forming the sheath when contacted with the tissue sample is greater than the resistivity of the tissue sample. The probe is received within the internal cavity of the sheath. The sheath is impervious to bacteria and viruses.Type: GrantFiled: June 2, 2006Date of Patent: October 18, 2011Assignees: The University of Sheffield, Sheffield Teaching Hospitals NHS Foundation TrustInventors: Brian Hilton Brown, John Anthony Tidy
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Patent number: 8041773Abstract: Computational grids have traditionally not scaled effectively due to administrative hurdles to resource and user participation. Most production grids are essentially multi-site supercomputer centers, rather than truly open and heterogeneous sets of resources that can join and leave dynamically, and that can provide support for an equally dynamic set of users. Large-scale grids containing individual resources with more autonomy about when and how they join and leave will require self-organizing grid middleware services that do not require centralized administrative control. Dynamic discovery of high-performance variable-size clusters of grid nodes provides an effective solution for implementation of grids. A brute force approach to the problem of identifying these “ad-hoc clusters” would require excessive overhead in terms of both message exchange and computation.Type: GrantFiled: September 23, 2008Date of Patent: October 18, 2011Assignee: The Research Foundation of State University of New YorkInventors: Nael Abu-Ghazaleh, Weishuai Yang, Michael Lewis
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Patent number: 8039589Abstract: Variant costimulatory polypeptides, nucleic acids encoding such polypeptides, and methods for using the polypeptides and nucleic acids to enhance a T cell response are provided herein.Type: GrantFiled: October 31, 2007Date of Patent: October 18, 2011Assignee: Mayo Foundation for Medical Education and ResearchInventor: Lieping Chen
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Patent number: 8039502Abstract: A new class of phosphoinositide-dependent kinase-1 (PDK-1) inhibitors of Formula I: wherein X wherein X is —CF3, Ar is selected from and R is selected from where R? is L-Lys, D-Lys, ?-Ala, L-Lue, L-Ile, Phe, SO2CH2CH2NH2, SO2NH2, Asn, Glu or Gyl, and R? is methyl, ethyl, allyl, CH2CH2OH, CH2CN, CH2CH2CN, CH2CONH2,Type: GrantFiled: July 24, 2008Date of Patent: October 18, 2011Assignee: The Ohio State University Research FoundationInventors: Ching-Shih Chen, Hao-Chieh Chiu, Dasheng Wang, John S. Gunn, Larry S. Schlesinger
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Patent number: 8037647Abstract: The present invention relates to apparatus and systems for absorbing seismic energy to prevent non-linear displacement in a structure. A seismic damper according to embodiments of the present invention includes a flat plate which can be perforated to include a plurality of apertures and/or cut-outs. A central aperture is formed in the flat plate and one or more cut-outs are formed along outer edges of the flat plate. The area of the flat plate between the aperture and the cut-outs forms one or more nodes on which stresses from seismic activity are focused, and which can deform to absorb energy, thereby reducing or preventing non-linear displacement of a brace system to which the seismic damper is attached. The nodes are located at the intersection between one or more tabs, the tabs being arranged to be connected to braces within the brace system.Type: GrantFiled: October 30, 2007Date of Patent: October 18, 2011Assignee: University of Utah Research FoundationInventors: Lawrence D. Reaveley, Tyler J. Ross
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Patent number: 8039605Abstract: Disclosed herein are novel methods for screening for compounds useful in treating or preventing tuberculosis. In exemplary embodiments, screening methods are based on the implementation or manipulation of triacylglycerol hydrolase like polypeptides or polynucleotides encoding the same. The methods are useful in identifying agents active against TB infection.Type: GrantFiled: August 25, 2009Date of Patent: October 18, 2011Assignee: University of Central Florida Research Foundation, Inc.Inventors: Pappachan E. Kolattukudy, Chirajyoti Deb, Jaiyanth Daniel
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Patent number: 8039669Abstract: The invention provides methods and reagents for the metathesis of secondary amides via a transacylation mechanism employing catalytic quantities of an imide initiator and a Brønsted base. Equilibrium-controlled exchange between various amide reactant pairs is demonstrated for substrates bearing a variety of N-alkyl and N-aryl substituents.Type: GrantFiled: December 1, 2008Date of Patent: October 18, 2011Assignee: Wisconsin Alumni Research FoundationInventors: Christen Bell Smith, Denis A. Kissounko, Samuel H. Gellman, Shannon S. Stahl
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Patent number: 8039861Abstract: The present invention relates to a gallium nitride (GaN) compound semiconductor light emitting element (LED) and a method of manufacturing the same. The present invention provides a vertical GaN LED capable of improving the characteristics of a horizontal LED by means of a metallic protective film layer and a metallic support layer. According to the present invention, a thick metallic protective film layer with a thickness of at least 10 microns is formed on the lateral and/or bottom sides of the vertical GaN LED to protect the element against external impact and to easily separate the chip. Further, a metallic substrate is used instead of a sapphire substrate to efficiently release the generated heat to the outside when the element is operated, so that the LED can be suitable for a high-power application and an element having improved optical output characteristics can also be manufactured. A metallic support layer is formed to protect the element from being distorted or damaged due to impact.Type: GrantFiled: March 28, 2011Date of Patent: October 18, 2011Assignees: Seoul Opto Device Co., Ltd., Postech FoundationInventor: Jong Lam Lee
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Patent number: 8040960Abstract: A method for transmitting a signal in a wireless communication system. The method comprises the steps of: grouping two subcarriers having different channel characteristics; identifying a number of all cases occurring when either equal symbols or different symbols, among symbols determined upon applying a first modulation scheme, are mapped to the two subcarriers; and mapping two subcarriers corresponding to each of the number of all cases to one symbol according to a second modulation scheme, and transmitting the signal, wherein a modulation order of the second modulation scheme is two times higher than a modulation order of the second modulation.Type: GrantFiled: October 31, 2007Date of Patent: October 18, 2011Assignees: Samsung Electronics Co., Ltd., Industry-Academic Cooperation FoundationInventors: Sang-Min Lee, Myeon-Gyun Cho, Yu-Seok Kim, Keum-Chan Whang, Jae-Won Kang, Sun-Young Lee
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Patent number: 8040952Abstract: Scalable multi-view image encoding and decoding methods and apparatuses are provided. The scalable multi-view image encoding and decoding methods and apparatuses filter multi-view images input from a plurality of cameras in spatial-axis and in temporal-axis directions using motion compensated temporal filtering (MCTF) or hierarchical B-pictures and scalably code the filtered multi-view.Type: GrantFiled: March 30, 2006Date of Patent: October 18, 2011Assignees: Samsung Electronics, Co., Ltd., Industry Academic Cooperation Foundation Kyunghee UniversityInventors: Gwang-Hoon Park, Won-jun Choi
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Patent number: PP22199Abstract: A new and distinct cultivar of crapemyrtle, ‘Gamad VII’ is provided. ‘Gamad VII’ is a Lagerstroemia indica×Lagerstroemia fauriei, which is characterized by compact growth habit, high Cercospora resistance, and early July flowering with abundant true pink flowers.Type: GrantFiled: May 18, 2010Date of Patent: October 18, 2011Assignee: University of Georgia Research Foundation, Inc.Inventor: Michael A. Dirr