Abstract: The invention relates to a second-generation-fatty acid conjugate and pharmaceutical compositions thereof. The second-generation-fatty acid conjugate are useful in the treatment of cancer in a human in need thereof.

Abstract: A method is disclosed for the direct synthesis of double stranded DNA molecules of a variety of sizes and with any desired sequence. The DNA molecule to be synthesis is logically broken up into smaller overlapping DNA segments. A maskless microarray synthesizer is used to make a DNA microarray on a substrate in which each element or feature of the array is populated by DNA of a one of the overlapping DNA segments. The complement of each segment is also made in the microarray. The DNA segments are released from the substrate and held under conditions favoring hybridization of DNA, under which conditions the segments will hybridize to form duplexes. The duplexes are then separated using a DNA binding agent which binds to improperly formed DNA helixes to remove errors from the set of DNA molecules. The segments can then be hybridized to each other to assemble the larger target DNA sequence.

Abstract: Briefly described, embodiments of this disclosure include methods of recovering bio-oil products, fuels, diesel fuels, and the like are disclosed.

Abstract: A synthesis route to grow textured thin film of gallium nitride on amorphous quartz substrates and on single crystalline substrates such as c-sapphire and polycrystalline substrates such as pyrolytic boron nitride (PBN), alumina and quartz using the dissolution of atomic nitrogen rather than molecular nitrogen to allow for growth at subatmospheric pressure.

Abstract: A nanowire memory device and a method of manufacturing the same are provided. A memory device includes: a substrate; a first electrode formed on the substrate; a first nanowire extending from an end of the first electrode; a second electrode formed over the first electrode to overlap the first electrode; and a second nanowire extending from an end of the second electrode corresponding to the end of the first electrode in the same direction as the first nanowire, wherein an insulating layer exists between the first and second electrodes.

Abstract: A method and system for controlling the transmission power of a terminal transmitting frames in a wireless communication system, the frames having a frame structure including a header field containing information related to a transmission rate and length of data transmitted in a frame and a data field having the data. The transmitting terminal transmits the header field to a receiving terminal at a maximum transmit power level available to the transmitting terminal so that second terminals other than the transmitting terminal and the receiving terminal within the wireless communication system can identify that resources are in use. The transmitting terminal transmits the data field at an optimum transmit power level great enough to allow the data field to reach the receiving terminal.

Abstract: The present invention includes a method and apparatus for monitoring drug compliance by detecting markers, such as odors, upon exhalation by a patient after medication is taken, wherein such markers result either directly from the medication itself or from an additive combined with the medication. In the case of olfactory markers, the invention preferably utilizes electronic sensor technology, such as the commercial devices referred to as “artificial noses” or “electronic noses,” to non-invasively monitor compliance. The invention further includes a reporting system capable of tracking compliance (remote or proximate) and providing the necessary alerts.

Abstract: Methods of reducing expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) and methods of treating a cancer in a cell are provided, the methods including contacting a cell with an effective amount of a PFKFB4 inhibitor. Short hairpin RNA (shRNA) and small interfering RNA (siRNA) inhibitors of PFKFB4 and their methods of use are also provided.

Abstract: Pharmaceutical compositions for treating and/or pre-treating or preconditioning the animal central nervous system against the effects of Alzheimer's Disease including the associated neurodegeneration and cognitive, behavioral and physical impairments. In one embodiment, an effective dose of deferoxamine (DFO) is administered to the upper one-third of the subject patient's nasal cavity to effectively bypass the blood-brain barrier, thereby allowing application of the DFO dose directly to the central nervous system.

Abstract: Compositions and methods for inhibiting undesirable plants.

Abstract: Embodiments of the subject invention relate to a gas sensor and method for sensing one or more gases. An embodiment incorporates an array of sensing electrodes maintained at similar or different temperatures, such that the sensitivity and species selectivity of the device can be fine tuned between different pairs of sensing electrodes. A specific embodiment pertains to a gas sensor array for monitoring combustion exhausts and/or chemical reaction byproducts. An embodiment of the subject device related to this invention operates at high temperatures and can withstand harsh chemical environments. Embodiments of the device are made on a single substrate. The devices can also be made on individual substrates and monitored individually as if they were part of an array on a single substrate. The device can incorporate sensing electrodes in the same environment, which allows the electrodes to be coplanar and, thus, keep manufacturing costs low.

Abstract: A method for reconstructing an image from emission data includes generating a compressed point-spread function matrix, generating an accumulated attenuation factor; and performing at least one image projection operation on an image matrix of the emission data using the compressed point-spread function matrix and the accumulated attenuation factor. The image projection operation can include rotating an image matrix and an exponential attenuation map to align with a selected viewing angle. An accumulated attenuation image is then generated from the rotated image matrix and rotated exponential attenuation map and a projection image is generated for each voxel by multiplying the accumulated attenuation image and point spread function matrix for each voxel. The rotating and multiplying operations can be performed on a graphics processing unit, which may be found in a commercially available video processing card, which are specifically designed to efficiently perform such operations.

Abstract: Compositions, methods, and combination therapies for the treatment of cancers, including lymphomas, leukemias, melanomas, lung cancer, and metastatic disease, are provided. Specifically, compositions comprising ligands to Pgrmc1 are disclosed for use in treating and inhibiting tumor growth and progression and inhibition of metastases. The compositions and methods using these ligands can be used alone or in combination with other reagents and cancer treatment modalities.

Abstract: A decentralized scheduling method in a wireless ad hoc network is provided which includes grouping nodes in the network cluster by cluster, determining a cluster head of each cluster, and sequentially performing scheduling cluster by cluster. Accordingly, it is possible to provide an efficient cluster-based scheduling method which is quickly adapt to changes and reduces power consumption.

Abstract: The present invention discloses a set of glycosylated warfarin analogs which are useful as anti-tumor or anti-metastatic agents and as reagents for studying sugar uptake in cells.

Abstract: An embodiment of the invention is a device for photo-stimulated color emission having at least one plurally doped semiconducting nanoparticle comprising at least one semiconducting material and a plurality of at least one dopant coupled with an irradiation source such that the plurally doped semiconducting nanoparticle emit electromagnetic radiation at two or more wavelengths where the intensities of the emissions depend on the intensity of the irradiation. In an embodiment of the invention, the plurally doped semiconducting nanoparticle can be a doped core/shell nanoparticle where the plurality of dopants can reside in exclusively the core, exclusively the shell, or in both the core and shell.

Abstract: A 3D contents data encoding method includes receiving a plurality of primitive data contained in 3D contents data, and encoding each of the received primitive data in accordance with a predetermined encoding order for the primitive data.

Abstract: The present invention relates to an agricultural water-recycling system comprising an iron (Fe)-ionizing module and a method of recycling agricultural water using the same, and more particularly to an agricultural water-recycling system comprising an iron (Fe)-ionizing module and a method of recycling agricultural water using the same, in which phosphorus (P) contained in effluent from a sewage treatment plant is removed by using the iron (Fe)-ionizing module comprising an iron (Fe)-ionizing electrode consisting of an iron plate serving as a cathode and a titanium plate serving as an anode and an electrode-washing device. According to the present invention, an effluent treatment process of a sewage treatment plant and an electrode washing process needed for iron ionization can be simultaneously performed, the iron ionization is controlled depending on the concentration of phosphorus contained in the effluent, thereby improving effluent treatment efficiency.

Abstract: Crosslinked proteins, proteins and polymers, and polymers and methods of making the same are disclosed. In one illustrative embodiment, a method is provided comprising the steps of attaching a chelator to one or more polymers; creating a coordination complex between the first protein, the second protein, and a metal ion; and crosslinking the first and second proteins by exposing the coordination complex to an oxidant.

Abstract: A silicon electro-optic waveguide modulator is formed using a metal-oxide-semiconductor (MOS) configuration. Various embodiments are described using different modes of operation of the MOS diode and gate oxide thicknesses. In one example, a high-speed submicron waveguide active device is formed using silicon-on-insulator. A micro-ring resonator intensity-modulator exhibits switching times on the order of tens of pS with modulation depth of 73% with a bias voltage of 5 volts.