Abstract: It is intended to provide a promoter for inducing expression selectively and strongly in an immunocompetent cell and/or a blood cell such as a lymphocyte. In the invention, the object was achieved by finding that HHV6 MIE promoter, HHV7 MIE promoter and HHV7 U95 promoter unexpectedly induce a specific expression in an immunocompetent cell and/or a blood cell such as a T lymphocyte. By utilizing the promoters, a selective delivery of a DNA vaccine or the like can be realized.

Abstract: An NMR probe which includes a probe matrix (24) having a void sample (28) volume therein. A conductive coil (16, 26) can be at least partially embedded in the probe matrix (24). By embedding the conductive coil (16, 26) in the probe matrix (24), the fill-factor can be significantly increased. NMR probes can be formed by a method which includes wrapping a conductive wire (16) around a coil form (18) to produce a coil precursor assembly. The probe matrix (24) can be formed around the conductive wire and coil form with a matrix material using any suitable technique such as soft lithography and/or molding. The coil form can be removed from the probe matrix leaving a void sample volume (28) in the probe matrix. Advantageously, the NMR probes of the present invention allow for fill-factors approaching and achieving 100%.

Abstract: A bead for stitching, a vacuum cap for suction-holding an internal organ, and an apparatus for stitching an internal organ using the vacuum cap are disclosed. The bead includes a through hole which is formed vertically through the bead so that a stitching fiber passes through the bead. At least one of both ends of the bead is inclined relative to a transverse direction of the bead. The bead is shaped to pass through a hole formed in a stitching needle. That apparatus includes an endoscope tube having a stitching needle which is movable in a longitudinal direction thereof and a suction tube for drawing air, and a vacuum cap having at an end thereof a fastening hole to which the endoscope tube is fastened. A suction hole is formed in the vacuum cap in a direction crossing the fastening hole.

Abstract: The invention provides a pharmaceutical composition comprising at least one polypeptide of the following (a) to (d): (a) a polypeptide comprising the amino acid sequence of SEQ ID NO:1; (b) a polypeptide comprising an amino acid sequence comprising one or more amino acid deletions, insertions, substitutions or additions in the amino acid sequence of the above (a) and having a platelet aggregation inhibitory activity and/or a platelet adhesion inhibitory activity; (c) a polypeptide comprising the amino acid sequence of SEQ ID NO:3; and (d) a polypeptide comprising an amino acid sequence comprising one or more amino acid deletions, insertions, substitutions or additions in the amino acid sequence of the above (c) and having a platelet aggregation inhibitory activity and/or a platelet adhesion inhibitory activity, as an active component.

Abstract: A photolithography system using an optical microscope is provided that can form various types of selective patterns at a low cost in small-scale research using unit-size silicon substrates which is not targeted for mass production, without requiring an expensive photomask.

Abstract: The present invention provides a unit dosage of Apadenoson, a pharmacological stress agent, and use of the same as a pharmacologic agent for myocardial perfusion imaging.

Abstract: A transparent electrode multilayer film has at least one group III doped ZnO layer and at least one metal layer, where layers of doped ZnO alternate with metal layers. When a plurality of group III doped ZnO layers are present, the doped ZnO layers can have the same or different dopants and one or more dopants can be present in a doped ZnO layer. When a plurality of metal layers is present, the layers can be of the same or different metals, and a metal layer can be a single metal or a combination of two or more metals. The multilayer film can be free standing, but generally includes a substrate. Advantageous substrates are transparent and can be flexible for use as a flexible electrode. A method to form a transparent conductive multilayer film involves depositing at least one layer of a group III doped ZnO and at least one metal layer on a substrate.

Abstract: In a method for using resources in a communication system, a communication region is divided into inter-sector boundary regions, sector central regions, and a sector common region, and predetermined resources are allocated to the divided regions.

Abstract: Disclosed are methods for isolating cell populations enriched in tumor stem cells (cancer stem cells), and isolated cell populations substantially enriched in cancer stem cells that are tumorigenic in vivo. Also provided are new methods of tumor diagnosis and classification and personalized methods of treatment for subjects with tumors, based on the availability of populations of cancer stem cells derived from the subject's tumor using the disclosed methods.

Abstract: An apparatus for measuring light proceeding backward to which a plasmonic device is applied is disclosed. A disclosed optical apparatus according to the present invention includes: a plasmonic device including a thin metal film having apertures having a nano-sized diameter, disposed close to an object, and generating a near field in front of the apertures; a polarization modulation unit for adjusting the polarized state of light entering through the apertures of the plasmonic device, and making the light reflecting the strength of the near field proceed backward through the nano-apertures of the plasmonic device, and a measuring unit detecting properties of the object from the light proceeding backward from the polarization modulation unit.

Abstract: Techniques for bisecting a symmetric, substantially transmissive two-port network (a THRU structure) through an optimization solution of the relevant equations defined by transmission matrix mathematics are described. Bisect de-embedding may be performed using a single substantially symmetric THRU structure, a first half of a first substantially symmetric THRU structure and a second half of a second substantially symmetric THRU structure, and by combining bisect de-embedding with conventionally known de-embedding techniques.

Abstract: A method is provided to couple an aryl halide to an alkyne comprising reacting a compound of the formula ArX, wherein Ar is a substituted or unsubstituted aryl group and X is I or Br, with a compound of the formula HC?C—R1 wherein R1 is a substituted or unsubstituted organic group, in the presence of an effective amount of a phosphine-free, oxime-free palladium catalyst; (C1-C4)alkyl N+(?OAc) or an alkali metal carbonate, to yield a compound of the formula Ar—C?C—R1, wherein the reaction is carried out in the absence of an organic amine or copper(I).

Abstract: An airflow window system that includes at least three glazing layers positioned roughly parallel to each other to define at least two internal airflow cavities within the window system. A first of the glazing layers is adjacent a first of the airflow cavities, a second of the glazing layers is adjacent a second of the airflow cavities, and a center glazing layer is between the first and second glazing layers and separates the first and second airflow cavities. Airflow cavity openings are located adjacent the uppermost and lowermost extents of each airflow cavity, and airflow is enabled through the first airflow cavity between the openings thereof and enabled through the second airflow cavity between the openings thereof. The window system operates as a crossflow heat exchanger capable of supplying fresh outdoor air to an enclosed indoor space, while thermally tempering the incoming fresh air with outgoing indoor air.

Abstract: Methods are provided for mechanically chopping nanotubes and other nanoscale fibrous materials. The method includes forming a macroscale article which include the nanoscale fibers, and then mechanically cutting the macroscale article into a finely divided form. In one embodiment, these steps are repeated. The nanoscale fibers may be carbon nanotubes, which optionally are aligned in the macroscale article. The macroscale article may be in the form of or include one or more buckypapers. In one embodiment, the macroscale article further includes a solid matrix material in which the nanoscale fibers are contained or dispersed. The forming step can include making a suspension of nanoscale fibers dispersed in a liquid medium and then solidifying the liquid medium to form the macroscale article. After the mechanical cutting step, the medium can be dissolved or melted to enable separation of the chopped nanoscale fibers from the medium.

Abstract: An efficient new route for the preparation of dihydroeponemycin, an active eponemycin derivative, is provided, which includes the synthesis of the intermediate compound, a hydroxymethyl-substituted enone. In addition, a method is provided for synthesizing inhibitors, which includes PI?-modified analogues. These analogues selectively bind to a major immunoproteasome catalytic subunit LMP2 and inactivate its proteolytic activity in a method of treating diseases, including myeloma and other cancers, Huntington's disease and Alzheimer's disease.

Abstract: A method and design is provided for distributing and storing sets of temporally ordered information in a systematic and sequential fashion. This method is based on a model of how the brain functions in the distribution and storage of temporally ordered memories, but it can also be applied to the design of new biological, electronic or optical devices. These devices may be used in the testing and development of new therapeutic drugs, in the detection of toxic agents or impaired performance, or in the development of new industrial and consumer devices in which the orderly storage of sequential information is important.

Abstract: A high-pass two-dimensional ladder network has been described for high-field MRI and credential applications. The next-to-highest eigenvalue of the network corresponds to a normal mode giving rise to B1 fields with good spatial homogeneity above the resonator plane. Other eigenvalues may also be used for specific imaging applications. In its most basic form, the ladder network is a collection of inductively coupled resonators where each element of the array is represented by at least one conducting strip having a self-inductance L, joined by a capacitor C at one or more points along each resonator. In the strong coupling limit of the inductively coupled high-pass two-dimensional ladder network resonator array, the array produces a high-frequency resonant mode that can be used to generate the traditional quadrature B1 field used in magnetic resonance imaging, and in the limit of weak or zero coupling reduces to a phased array suitable for parallel imaging applications.

Abstract: The invention involves PKC? signaling. The invention provides, for example, transgenic animals, inhibitors of PKC? signaling, methods for inhibiting PKC? signaling, methods for identifying inhibitors of PKC? signaling, and methods for diagnosing cancer.

Abstract: A package for a semiconductor chip or other heat producing device has a supporting substrate to which the devices mount and electrically connect. An enclosure is formed over the heat producing devices and filled with a supercritical fluid that transports heat from the devices to a heat sink in thermal contact with the enclosure.

Abstract: The present invention provides compositions and methods for modulating the communication and virulence of quorum sensing bacteria. In various exemplary embodiments, the invention provides a combinatorial library of quorum sensing compounds including synthetic analogs of naturally occurring and non-naturally occurring acyl-homoserine lactone (AHL) analogs, and methods of synthesizing and using these compounds.