Abstract: A method of generating cultured chondrocytes/endochondral bone cells is provided. The method comprising isolating chondrocytes from mandibular condyle tissue, and culturing the isolated chondrocytes. A method of isolating chondrocytes from mandibular condyle tissue is further provided. The method comprises isolating mandibular condyle tissue from a mammal and treating the mandibular condyle tissue so as to selectively remove fibroblast-like cells and/or myocytes therefrom, the modified mandibular condyle tissue including chondrocytes, and selectively collecting the chondrocytes from the modified mandibular condyle tissue.
Type:
Grant
Filed:
July 28, 2003
Date of Patent:
January 5, 2010
Assignee:
Technion Research & Development Foundation Ltd.
Abstract: A fast automatic linear off-resonance correction method for MRI data uses a set of widely spaced demodulation frequencies to estimate a low-resolution field map from the image itself. A linear map is determined by fitting to this low-resolution map using a maximum-likelihood estimator with weights proportional to the pixel intensity.
Type:
Grant
Filed:
August 21, 2007
Date of Patent:
January 5, 2010
Assignee:
University of Virginia Patent Foundation
Abstract: A secure apparatus, system, device and method for coding surface acoustic wave identification tags and sensors to enable unique sensor operation and identification for a multi-sensor environment. In an embodiment, a pseudo noise sequence is applied to the orthogonally coded signal for increased security. An orthogonal frequency coding technique is applied to the SAW tag using periodic reflector gratings for responding to an orthogonal interrogation signal to transmit the sensor identification and sensed data. A transceiver interrogates the sensor with a stepped chirp corresponding to the orthogonal frequency coded chip frequency response, receives a response from the SAW device, applies an oppositely stepped chirp to the response and then uses matched filtering to produce a compressed pulse. The orthogonal frequency coding technique has an inherent advantage of processing gain, code division multiple access, spread spectrum and security.
Type:
Grant
Filed:
August 12, 2005
Date of Patent:
January 5, 2010
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A system provides for remote monitoring using asynchronous code division multiple access (CDMA) communication techniques between a base station and one or more transponders. Each transponder is attached or otherwise associated with an object or an environment to be monitored. Upon receipt of an interrogation signal, a transponder generates and transmits a coded transponder signal containing the monitored data. The coded transponder signal is generated using a spreading code. Each transponder is associated with a unique, mutually exclusive set of spreading codes. Each spreading code is based on a unique transponder address and the monitored data to be sent. A detector asynchronously monitors received signals for any of the available spreading codes. Once the detector detects a particular spreading code, the base station can identify the source transponder and extract the monitored data.
Type:
Grant
Filed:
August 10, 2004
Date of Patent:
January 5, 2010
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
Timothy Michael Schaefer, Jonathan Darrel Coker, Rick Allen Philpott, Edward Brian Welch, David R. Holmes, III
Abstract: Disclosed herein is an apparatus and method for deforming a curved surface using a three-dimensional target curve. The curved surface deformation apparatus of the present invention includes object curved surface selection means, sample vertex extraction means, basis function calculation means, target curve input means, control point variation calculation means, and object curved surface deformation means. The object curved surface selection means selects all or part of the curved surface of the NURBS model. The sample vertex extraction means extracts a plurality of vertexes from the object curved surface. The basis function calculation means calculates a basis function of the object curved surface. The target curve input means inputs a target curve, composed of a plurality of target. The target curve projection means projects the target curve onto the object curved surface.
Type:
Grant
Filed:
January 12, 2007
Date of Patent:
January 5, 2010
Assignee:
Chung-Ang University Industry-Academic Cooperation Foundation
Inventors:
Young Ho Chai, Jung Hoon Kwon, Jeong In Lee
Abstract: Thermoplastic surface modification is achieved with photocatalysts, such as titanium dioxide, tungsten oxide and mixtures thereof. A uniform coating of a powdered photocatalyst is applied to a thermoplastic surface that is wetted with an organic solvent. The coating is in a range between approximately 1.5 mg/cm2 to approximately 2.5 mg/cm2. After the uniform coating of photocatalyst is dried, the thermoplastic surface is heated to a temperature above its softening temperature, usually in a range between approximately 80° C. to approximately 130° C.; then, a mild pressure is applied to imbed the photocatalyst into the surface of the thermoplastic sheet. The method of modification is inexpensive, long-lasting and non-detrimental to the thermoplastic surface. A surface is provided with improved aesthetic appearance, extended lifetime and sustained protection from undesirable growth of nuisance organisms, such as algae, fungus, bacteria, mold, mildew and the like.
Type:
Grant
Filed:
December 10, 2004
Date of Patent:
January 5, 2010
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: Disclosed is a system and a method for rectifying stereo images, which are acquired by two cameras, in real-time by using a calibration matrix resulting from camera calibration. The system includes a coordinate generation module; a rectification coordinate generation module; a bilinear interpolation value generation module; a rectification coordinate memory; a bilinear interpolation memory; an image buffer; an rectification module; and a control module. A structure of a hardware system capable of real-time stereo rectification is provided, and the operation results have been verified by implementing a hardware device. The real-time stereo rectification system makes it possible to acquire rectified images in real-time without using a separate computer system or a software program.
Type:
Grant
Filed:
February 21, 2007
Date of Patent:
January 5, 2010
Assignee:
Sungkyunkwan University Foundation for Corporate Collaboration
Inventors:
Jae Wook Jeon, Seung Hun Jin, Jung Uk Cho, Sung Kee Park, Munsang Kim, Kyoung Mu Lee, Jong Eun Byun
Abstract: The effect of the action of collagenase in treating lesions containing collagen or mixed fibrin clots (e.g., burns or ulcers) is improved by applying collagenase to the wound in combination with an organogel and a phosphatidylcholine, of which lecithin is a readily available source, particularly when the collagenase is first mixed and stored with that choline and an organic solvent and is subsequently mixed with a second individually stored formulation comprising a gel-forming agent and water, the two formulations individually having satisfactory shelf lives and the resultant mixture being applied to the lesion promptly after being formed.
Type:
Grant
Filed:
March 30, 2005
Date of Patent:
January 5, 2010
Assignee:
Research Foundation of State University of New York
Inventors:
Harry Soroff, Marcia Simon, Thomas Fallon, Peter Fallon, Gabriele Hatch
Abstract: A shadow aperture backscatter radiography (SABR) system includes at least one penetrating radiation source for providing a penetrating radiation field, and at least one partially transmissive radiation detector, wherein the partially transmissive radiation detector is interposed between an object region to be interrogated and the radiation source. The partially transmissive radiation detector transmits a portion of the illumination radiation field. A shadow aperture having a plurality of radiation attenuating regions having apertures therebetween is disposed between the radiation source and the detector. The apertures provide illumination regions for the illumination radiation field to reach the object region, wherein backscattered radiation from the object is detected and generates an image by the detector in regions of the detector that are shadowed by the radiation attenuation regions.
Type:
Grant
Filed:
April 30, 2008
Date of Patent:
January 5, 2010
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
Daniel Shedlock, Alan M. Jacobs, Sharon Auerback Jacobs, Edward Dugan
Abstract: A technique for net shaping gear teeth of a high performance power transmission gear from a powder metal workpiece includes heating a powder metal workpiece in the form of a near net shaped gear blank having gear teeth surfaces above its critical temperature to obtain an austenitic structure throughout its surfaces, isothermally quenching the workpiece at a rate greater than the critical cooling rate of its surfaces to a uniform metastable austenitic temperature just above the martensitic transformation temperature, rolling the gear teeth surfaces of the workpiece to a desired outer peripheral profiled shape between opposed dies, each die having an outer peripheral profiled surface, while holding the workpiece at the uniform metastable austenitic temperature, the gear teeth surfaces undergoing densification, plastic deformation, and strengthening as a result of the rolling operation, and cooling the workpiece through the martensitic range to thereby harden the surfaces of the gear teeth.
Type:
Grant
Filed:
March 17, 2004
Date of Patent:
January 5, 2010
Assignee:
The Penn State Research Foundation
Inventors:
Nagesh Sontti, Maurice F. Amateau, Suren B. Rao
Abstract: Efficient apparatus, methods, systems and devices to generate, transmit and detect optical differential polarization-phase-shift keying signals are disclosed for high spectral efficiency optical communication systems. It includes an electrical encoder and an optical encoder for generation of differentially encoded polarization-phase modulated optical signals and optical demodulators and balanced detectors for detection of the optical signals. The optical signals are transmitted through optical fiber links or free space. The electrical encoder maps independent data channels into differentially-encoded data sequences. In the optical encoder, the encoded data sequences from the electrical encoder drive optical modulators to generate differentially-encoded polarization-phase modulated optical signals at a symbol rate equal to the bit rate of each input data channel.
Type:
Grant
Filed:
March 3, 2006
Date of Patent:
January 5, 2010
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: The invention provides a novel amino acid, neo-tryptophan, as well as polypeptides containing this novel amino acid such as neurotensin analogs. In addition, the invention provides neo-tryptophan derivatives, serotonin-like neo-tryptophan derivatives, and polypeptides containing such derivatives. The invention also provides methods for making neo-tryptophan, neo-tryptophan derivatives, serotonin-like neo-tryptophan derivatives, and compositions containing these compounds. Further, the invention provides methods for inducing a neurotensin response in a mammal as well as methods for treating a mammal having a serotonin recognition molecule.
Type:
Grant
Filed:
June 14, 2006
Date of Patent:
January 5, 2010
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
Elliott Richelson, Bernadette Marie Cusack, Yuan-Ping Pang, Daniel J. McCormick, Abdul Fauq, Beth Marie Tyler, Mona Boules
Abstract: Uniaxially patterned (UAP) dielectric layers have an optical anisotropy that can be dynamically controlled. In a three-layer optical waveguide structure, the pattern can be included in the core or in a cladding layer. The pattern influences the polarization properties of radiation propagating in the structure. Predicated on the effect are devices such as a polarization-insensitive amplifier, a polarizer, an optically controlled polarization switch, and an optically controlled modal coupler.
Type:
Grant
Filed:
May 23, 2006
Date of Patent:
January 5, 2010
Assignee:
Research Foundation of State University of New York
Abstract: The present invention provides methods for inhibiting the growth of androgen-independent prostate cancer tumor cells in a human comprising administering to the human. The invention further provides pharmaceutical and nutraceutical compositions containing chroman-derived compounds useful in the alleviation of cancer.
Abstract: The present invention relates to a method for inducing the differentiation of CD34+ hematopoietic stem cells into megakaryocytes and platelets, more particularly, a method for inducing the differentiation of CD34+ hematopoietic stem cells into megakaryocytes and platelets comprising the steps of coculturing CD34+ hematopoietic stem cells with stromal cells and adding the compound of Formula 1.
Type:
Application
Filed:
February 2, 2009
Publication date:
December 31, 2009
Applicant:
Ewha University-Industry Collaboration Foundation
Inventors:
Jhon Gil-Ja, Limb Jin-Kyung, Han So-Yeop
Abstract: Disclosed are a clustering device for a flash memory and a method thereof. The clustering device for a flash memory in accordance with an embodiment of the present invention can gather pages having similar update times and perform a write operation of the pages in a same block. Accordingly, the writing performance of the flash memory can be improved and the lifetime of the flash memory can be increased.
Type:
Application
Filed:
June 29, 2009
Publication date:
December 31, 2009
Applicant:
KOREA POLYTECHNIC UNIVERSITY Industry and Academic Cooperation Foundation
Inventors:
Ji Woong CHANG, Se Mi Park, Duck Ho Bae, Sang Wook Kim
Abstract: Provided herein are mitochondrial-nuclear exchanged cells and animals comprising mitochondrial DNA (mtDNA) from one subject and nuclear DNA (nDNA) from a different subject. Methods for producing a mitochondrial-nuclear exchanged animal and animals made by the methods are provided. Also provided are methods of screening for agents useful for treating a disease or disorder using mitochondrial-nuclear exchanged animals or cells, tissues or organs thereof.
Type:
Application
Filed:
June 17, 2009
Publication date:
December 31, 2009
Applicant:
The UAB Research Foundation
Inventors:
Scott Webster Ballinger, Danny R. Welch, Robert Allen Kesterson, Larry W. Johnson
Abstract: An alloy including a Pt-group metal, Ni and Al, wherein the concentration of Al is limited with respect to the concentration of Ni and the Pt-group metal such that the alloy includes substantially no ?-NiAl phase, and wherein the Pt-group metal is present in an amount sufficient to provide enhanced hot corrosion resistance.
Type:
Application
Filed:
May 4, 2007
Publication date:
December 31, 2009
Applicant:
Iowa State University Research Foundation, Inc.
Abstract: The present invention relates to a compound having benzopyran core, a preparation method of the derivatives by liquid phase synthesis and solid phase synthesis through diversity-oriented synthesis, and an anticancer agent comprising the compound that exhibit excellent cytotoxicity against cancer cells.
Type:
Application
Filed:
June 9, 2009
Publication date:
December 31, 2009
Applicant:
SNU R&DB Foundation
Inventors:
Seung Bum Park, Hwan Jong Jang, Sung Kon Ko, EunHa Kim, Sangmi Oh, Jongmin Park
Abstract: The subject invention pertains to a method and apparatus for sensing nitroaromatics. The subject invention can utilize luminescent, for example fluorescent and/or electroluminescent, aryl substituted polyacetylenes and/or other substituted polyacetylenes which are luminescent for sensing nitroaromatics. In a specific embodiment, the subject invention can utilize thin films of fluorescent and/or electroluminescent aryl substituted polyacetylenes and/or other substituted polyacetylenes which are fluorescent and/or electroluminescent. In a specific embodiment, the fluorescence from thin films of fluorescent, substituted polyacetylene, such as—poly-[1-phenyl-2-(4-trimethylsilylphenyl)ethyne] (PTMSDPA) is strongly quenched by the vapors of a variety of nitroaromatic compounds present at levels ranging from parts-per-million to parts-per-billion in air.
Type:
Application
Filed:
March 28, 2007
Publication date:
December 31, 2009
Applicant:
University of Florida Research Foundation, Inc.