Abstract: Methods of optimizing additive manufacturing processes for improved efficiencies and accuracies, particularly by simplifying the user interface portions of the processes. The methods use path-finding calculations, such as vector fields, vector trails, and texture maps, to form accurate models from which replica composite objects can be printed, without requiring complex parameter inputs and calculations from the user. The methods measure and plot vector fields by considering the location of a particle within the volume of an object at various points of time to develop a strand-like model that is used to manufacture a replica object.

Abstract: Provided is a database journaling method and apparatus for storing a log file in a storing apparatus by performing a lesser number of record commands to decrease a volume of data to be input and output by the storing apparatus, and the database journaling method may include determining whether a database is changed based on an operation performed on data in the database, generating a log file including log entries for the database when the database is changed, and performing journaling on the database by storing the generated log file in a storing apparatus, wherein each of the log entries includes a log record in which the data associated with a change of the database is stored, and metadata for the log record is recorded in a predetermined area embedded in the log record.

Abstract: Techniques are described for determining a voltammogram that characterizes a result of a fast-scan cyclic voltammetry process. The FSCV process can be performed using a sensing apparatus at least partially immersed in a volume of blood of a mammal. A system can process the voltammogram to determine a concentration of a neurochemical in the volume of blood of the mammal.

Abstract: Provided is an ultrasound diagnosis apparatus including a probe configured to transmit a plurality of plane waves at a plurality of steering angles and a controller configured to determine the plurality of plane waves so that a grating lobe of a synthetic transmit focusing beam pattern using the plurality of plane waves is located outside a region of interest.

Abstract: The present invention relates to methods of treating a patient who has colorectal cancer and to methods of reducing the likelihood that a patient will develop or experience a recurrence of colorectal cancer. The methods comprise a step of introducing, to the patient, an effective amount of an agent that targets an intestinal H+-coupled di/tripeptide transporter (PepT1). Useful compositions including, for example, the tripeptide KPV, vectors encoding such peptides, and cells (e.g., bacterial cells) including them, are also within the scope of the present invention, as are kits including such compositions.

Abstract: Devices and methods of allocating distributed energy resources (DERs) to loads connected to a microgrid based on the cost of the DERs are provided. The devices and methods may determine one or more microgrid measurements. The devices and methods may determine one or more real-time electricity prices associated with utility generation sources. The devices and methods may determine one or more forecasts. The devices and methods may determine a cost associated with one or more renewable energy sources within the microgrid. The devices and methods may determine an allocation of the renewable sources to one or more loads in the microgrid.

Abstract: This document provides methods and materials involved in extracting chromatin. For example, methods and materials for obtaining chromatin from formalin-fixed, paraffin-embedded (FFPE) tissues are provided.

Abstract: The present disclosure relates to a novel method for operating and controlling a vapor-compression cycle. The method of the present disclosure provides that a turbine-based expander in a heat pump model can achieve greater COP benefit in cooling than heating. Further, phase separation and an evaporator bypass are implemented within the turbine-based expander. Phase separation leads to successful energy recovery and compressor superheat control.

Abstract: A mechanical diagnosis method for combustion abnormality using engine noise includes: calculating an Energy K and a Loudness standard deviation index (NSTD) with Kurtosis analysis by a diagnosis controller 30 from noise data measured together with a signal component by rotation excitation of an engine 10; calculating a plurality of order frequency peak order component values by a Modulation Frequency Transform; and distinguishing a cylinder where abnormal combustion occurs from a cylinder where normal combustion occurs by applying a predetermined threshold to these calculated values, thereby classifying, by Modulation Frequency analysis, problem samples of the rotation excitation and combustion excitation influence of the engine in which the abnormality state determination of the engine has been difficult only with energy distribution while overcoming the limitation of Kurtosis analysis.

Abstract: A method for diagnosing a disease can include detecting, in a sample from a patient, an autoantibody binding to Septin-7. A polypeptide comprising Septin-7 or a variant thereof can be used for the diagnosis of a disease. Preferably, the polypeptide is used to detect an autoantibody binding to Septin-7 in a sample. A kit is useful for the diagnosis of a disease. The kit may include a polypeptide that includes Septin-7 or a variant thereof or a medical device that includes a polypeptide that includes Septin-7 or a variant thereof and an autoantibody to Septin-7.

Abstract: The present invention provides a compound having the structure: or a pharmaceutically acceptable salt or ester thereof, and a method of treating a subject afflicted with pain, a depressive disorder, a mood disorder or an anxiety disorder by administering the compound to the subject.

Abstract: An apparatus for injecting an infusion solution is provided, and the apparatus includes a housing including a receiving part to receive an infusion solution bag in the receiving part and an infusion solution tube connected with the infusion solution bag and withdrawn, and a pressing member received in the receiving part to self-inflate as air is supplied and to press the infusion solution bag.

Abstract: This present patent application relates to a method for controlling a targeted gene expression with an environmental trigger useful for manufacturing a natural product or an analogue thereof biologically. In particular, the present invention discloses an expression system comprises a gene expressing for a fusion protein of elastin-like polypeptides (ELPs) and a transcription factor, wherein a targeted gene expression is regulated by the phase change of the fusion protein initiated by an environmental trigger, including changes of temperature, pH value, ionic strength or a combination thereof. The method, the expression system and their products are within the scope of this invention.

Abstract: Herein provided is a new runner-type peanut variety designated ‘Georgia-18RU’ as well as the seeds, plants and derivatives of the new peanut variety ‘Georgia-18RU’. Also provided are tissue cultures of the new peanut variety ‘Georgia-18RU’ and the plants regenerated therefrom. Methods for producing peanut plants by crossing the new peanut variety ‘Georgia-18RU’ with itself or another peanut variety (such as another runner-type peanut variety) and plants produced by such methods are also provided. ‘Georgia-18RU’ is a unique runner-type peanut cultivar having a combination of high level of tomato spotted wilt virus (TSWV) resistance and leaf scorch resistance caused by Leptosphaerulina crassiasca (Séchet) Jackson and Bell, and high yield. ‘Georgia-18RU’ provides a medium maturity runner-type peanut cultivar with a prominent main stem, medium green foliage, medium-large runner seed size, and pink seedcoat color.

Abstract: A solid multiphase polymer blend material comprising: (i) a polyphenolic substance having a molecular weight of at least 500 g/mol; and (ii) a polyester having a molecular weight of at least 500 g/mol; wherein at least a portion of the polyphenolic substance is covalently bonded directly or through a linking moiety to the polyester. Methods for producing the blend material are also described, e.g., homogeneously melt blending a mixture comprising components (i) and (ii) under conditions resulting in covalent attachment of at least a portion of the polyphenolic substance directly or through a linking moiety to the polyester. Methods for producing objects made of the blend material by melt extrusion are also described.

Abstract: The present invention discloses mass spectrometry (MS)-based methods and tagging reagents for qualitative and quantitative analysis of post-translational modified (PTM) proteins in biological and clinical samples. The present invention utilizes thiol-containing tagging reagents which are able to bind to or derivatize biomolecules, preferably post-translational modified (PTM) polypeptides such as citrullinated and homocitrullinated polypeptides. The tagging reagents are preferably biotin-derived tags able to react with a side chain of the modified polypeptides.

Abstract: The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure: Formula (I)

Abstract: The present application relates generally to a process of manufacturing a plurality of products from chia seeds. The process comprises socking chia seeds in a large volume of water for a period of time followed by sonication at an elevated temperature to remove the soluble fiber, the mucilage of chia seeds using vacuum filtration. The oil component is extracted from mucilage removed chia seeds and the leftover is hydrolyzed in presence of an enzyme to afford a product of protein hydrolysates and a product of insoluble fiber of chia seeds. Both the process and the products are within the scope of this application.

Abstract: Provided is a holographic display apparatus capable of providing an expanded viewing window when reproducing a holographic image via an off-axis technique. The holographic display apparatus includes a spatial light modulator comprising a plurality of pixels arranged two-dimensionally; and an aperture enlargement film configured to enlarge a beam diameter of a light beam coming from each of the plurality of pixels of the spatial light modulator. The beam diameter of each light beam enlarged by the aperture enlargement film may be greater than the width of an aperture of each pixel of the spatial light modulator.