Abstract: Disclosed herein are a method and apparatus for encoding/decoding a deep neural network. According to the present disclosure, the method for decoding a deep neural network may include: in a plurality of layers of the deep neural network, entropy decoding quantization information for a current layer; performing dequantization on the current layer; and obtaining a plurality of layers of the deep neural network. At least one of global quantization and local quantization is performed on the current layer.
Type:
Application
Filed:
December 11, 2020
Publication date:
January 12, 2023
Applicants:
Korea Electronics Technology Institute, INDUSTRY-UNIVERSITY COOPERATION FOUNDATION KOAEA AEROSPACE UNIVERSITY
Inventors:
Byeong Ho CHOI, Sang Seol LEE, Sung Joon JANG, Sung Jei KIM, Jae Gon KIM, Hyeon Cheol MOON
Abstract: The present invention relates to a compound comprising an EZH2 inhibitor and an E3 ligase binder, and a pharmaceutical composition for preventing or treating EZH2-associated disease and a pharmaceutical composition for selective protein degradation containing the same as an active ingredient. Since the compound of the present invention can selectively degrade EZH2, it can be effectively used for the treatment of EZH2-related diseases and cancers, particularly, cancers in which EZH2 is overexpressed, and can be usefully used for the selective degradation of EZH2.
Type:
Application
Filed:
October 29, 2020
Publication date:
January 12, 2023
Applicant:
DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION
Inventors:
Ji-Hoon Yu, Chun Young lm, SoYoung Kim, Ye Ri Han, Doohyun Lee, Hui-Jeon Jeon, Sang-Hyun Min, Bae Jun Oh, Sang-Wook Park, Dong-Kyu Choi, Young-Kyu Kim, Sung Hwan Kim, Yuri Lee, Seungyeon Lee, Nam Hui Kim, Sang Bum Kim, Ju-Sik Min
Abstract: Provided is a switched capacitor-based electrical stimulation device which supplies a direct current (DC) power, detects a charging voltage charged in any one of a plurality of capacitors, controls the DC power supplied to a capacitor module to repeat a charging level and a resting level according to a charging pattern when the charging voltage is lower than a target voltage, and outputs an electric current to electrodes which contact a human body based on an output pattern.
Type:
Application
Filed:
May 26, 2022
Publication date:
January 12, 2023
Applicant:
Korea University Research and Business Foundation
Inventors:
Hyung-Min LEE, Kyeongho EOM, Han-Sol LEE, Minju PARK
Abstract: A selector according to an embodiment of the present disclosure includes a first electrode; a second electrode disposed opposite to the first electrode; an ion supply layer disposed between the first electrode and the second electrode to be on the side of the first electrode and doped with a metal, wherein the doped metal diffuses toward the second electrode; a switching layer disposed between the first electrode and the second electrode to be on the side of the second electrode, wherein the doped metal diffuses from the ion supply layer into the switching layer so that metal concentration distribution inside the switching layer is changed to generate metal filaments; and a diffusion control layer inserted between the ion supply layer and the switching layer, wherein the diffusion control layer serves to adjust electrical characteristics related to the generated metal filaments as the amount of the diffusing metal is adjusted in proportion to a thickness of the diffusion control layer.
Type:
Application
Filed:
September 21, 2021
Publication date:
January 12, 2023
Applicant:
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)
Inventors:
Jea Gun PARK, Soo Min JIN, Dong Won KIM, Hea Jee KIM, Dae Seong WOO, Sang Hong PARK, Sung Mok JUNG, Dong Eon KIM
Abstract: A modular robotic surgical system comprising: a base; a plurality of tool-receivers arranged as separate units, each tool-receiver unit operable to move an elongate surgical tool received therein; a plurality of interface coupling pairs, each coupling pair comprising a first coupler as part of the base and a second coupler as part of each of the tool-receiver units; wherein each of the tool-receiver units is independently and interchangeably attachable to the base via the coupling pair.
Type:
Application
Filed:
November 26, 2020
Publication date:
January 12, 2023
Applicants:
Microbot Medical Ltd., Technion Research & Development Foundation Limited
Inventors:
Simon SHARON, Idan BOADER, Evgeny KOFMAN, Eran COHEN, Eyal MORAG, Harel GADOT, Moshe SHOHAM
Abstract: The present disclosure provides isolated polynucleotides encoding a mature Mycobacterium tuberculosis protein selected from Ag85A, Ag85B, and Ag85C, where the protein does not include a signal for glycosylation, such as a N-glycosylation consensus sequon. Also disclosed are M. tuberculosis proteins selected from Ag85A, Ag85B, and Ag85C that do not include a signal for glycosylation, such as a N-glycosylation consensus sequon, and/or are not glycosylated, and methods for using the polynucleotides and proteins.
Type:
Application
Filed:
December 8, 2020
Publication date:
January 12, 2023
Applicant:
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
Abstract: The present application provides compositions and methods for preparing and using “heavy” nucleotide derivatives of thymidine or uridine by replacing the oxygen atom attached to one or more of positions with non-radioactive oxygen-18 (18O), administering it to a subject to target a tumor including incorporation into tumor cell DNA, and then treating the tumor with proton beam therapy to transmutate the 18O to 18F, resulting in a break of the new fluorine-phosphorous bond. This chemical event destabilizes ribose-phosphate DNA back-bone and base pairing thus produce single- and double strand breaks, clusters lesions that can lead to irreparable DNA damage and enhanced tumor cell killing. The atomic, chemical, and physical aspects result in the use of lower radiation doses and significantly alter acute and late morbidity of radiotherapy. Heavy thymidine and heavy uridine derivatives labeled with 18O have been made and tested.
Type:
Application
Filed:
June 27, 2022
Publication date:
January 12, 2023
Applicants:
UNIVERSITY OF VIRGINIA PATENT FOUNDATION, HAMPTON UNIVERSITY
Inventors:
Tyvin A. RICH, Dongfeng PAN, Mahendra D. CHORDIA
Abstract: Provided is a neuromorphic circuit including an input module configured to generate an input voltage, an output module configured to measure a current transmitted from the input module and generate an output voltage, synapse modules configured to electrically connect the input module and the output module and determine a current to be transmitted to the output module and including a memory element to which a weight is assigned, and a crossing module configured to control a direction of current flowing through the synapse modules.
Type:
Application
Filed:
May 26, 2022
Publication date:
January 12, 2023
Applicant:
Korea University Research and Business Foundation
Inventors:
Hyung-Min LEE, Minil KANG, Min-Seong UM
Abstract: An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative helical cuff body configured to be disposed around a nerve, and a plurality of electrically conductive contacts carried by the helical cuff body that are spaced from one another.
Type:
Application
Filed:
September 1, 2021
Publication date:
January 12, 2023
Applicant:
The Alfred E. Mann Foundation for Scientific Research
Inventors:
William Andrew Brandt, Brian Ralph Dearden
Abstract: There is set forth herein a method including building a first photonics structure using a first wafer having a first substrate, wherein the building the first photonics structure includes integrally fabricating within a first photonics dielectric stack one or more photonics device, the one or more photonics device formed on the first substrate; building a second photonics structure using a second wafer having a second substrate, wherein the building the second photonics structure includes integrally fabricating within a second photonics dielectric stack a laser stack structure active region and one or more photonics device, the second photonics dielectric stack formed on the second substrate; and bonding the first photonics structure and the second photonics structure to define an optoelectrical system having the first photonics structure bonded the second photonics structure.
Type:
Grant
Filed:
September 19, 2019
Date of Patent:
January 10, 2023
Assignee:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Inventors:
William Charles, Douglas Coolbaugh, Douglas La Tulipe, Gerald L. Leake, Jr.
Abstract: The invention generally provides methods of treating or preventing infection and/or disease associated with different fungal pathogens in a subject in need, using an isolated antiserum generated against an immunogenic peptide of one fungal pathogen that contains antibodies that cross-protect the subject from infection and/or disease associated with one or more different fungal pathogens. The antiserum may be generated against a Kexin peptide derived from one of a Pneumocystis, Aspergillus, Candida, or Cryptococcus fungal pathogen. The resulting cross-protective, isolated antiserum may be used as a therapeutic for treating or protecting a subject who receives the antiserum against infection and/or disease associated with multiple fungal pathogens, in addition to the pathogen against which the antiserum is generated.
Type:
Grant
Filed:
September 26, 2018
Date of Patent:
January 10, 2023
Assignee:
University of Georgia Research Foundation, Inc.
Inventors:
Karen A. Norris, Whitney Rabacal, Emily Rayens
Abstract: Disclosed is a method for operating a communication node supporting a low power mode in a wireless LAN. A method for operating a station, which includes a PCR and a WURx, comprises the steps of: allowing the WURx, which operates in a wake-up state, to receive a wake-up packet from an access point; transitioning an operating state of the PCR from a sleep state to the wake-up state when the wake-up packet is received; allowing the PCR, which operates in the wake-up state, to receive a data frame from an access point; and allowing the PCR to transmit, to the access point, a response to the data frame.
Type:
Grant
Filed:
December 8, 2020
Date of Patent:
January 10, 2023
Assignees:
Electronics and Telecommunications Research Institute, Korea National University of Transportation Industry-Academic Cooperation Foundation
Inventors:
Yong Ho Kim, Sung Hyun Hwang, Igor Kim, Seung Keun Park
Abstract: Disclosed are fast cell allocation scheduling device and method for a mobile node in a 6TiSCH network, in which when link quality of the mobile node is changed, a fixed path directed to a route node is allocated to establish a movement-route node fixed path minimizing a delay time between the mobile node and the route node.
Type:
Grant
Filed:
August 25, 2021
Date of Patent:
January 10, 2023
Assignee:
Pusan National University Industry-University Cooperation Foundation
Abstract: A compositions-of-matter in the form of HIPE-templated hydrogels, comprising a crosslinked polymer of zwitterionic monomers, which exhibit unusual antipolyelectrolyte characteristics, dual pH-, and temperature-responsiveness, as well as processes of obtaining the same and using the same.
Type:
Grant
Filed:
October 30, 2018
Date of Patent:
January 10, 2023
Assignee:
Technion Research & Development Foundation Limited
Abstract: There is set forth herein an integrated photonics structure having a waveguide disposed within a dielectric stack of the integrated photonics structure, wherein the integrated photonics structure further includes a field generating electrically conductive structure disposed within the dielectric stack; and a heterogenous structure attached to the integrated photonics structure, the heterogenous structure having field sensitive material that is sensitive to a field generated by the field generating electrically conductive structure.
Type:
Grant
Filed:
November 18, 2020
Date of Patent:
January 10, 2023
Assignees:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE, MORTON PHOTONICS INCORPORATION
Inventors:
Douglas Coolbaugh, Douglas La Tulipe, Paul A. Morton, Nicholas G. Usechak
Abstract: The present invention relates to a method for producing a carbon nanotube fiber aggregate and provides a carbon nanotube fiber aggregate having an improved level of alignment through ultrasonic wave application and low speed recovery.
Type:
Grant
Filed:
October 27, 2017
Date of Patent:
January 10, 2023
Assignee:
POSTECH ACADEMY-INDUSTRY FOUNDATION
Inventors:
Eugene Oh, Juhan Kim, Ji Eun Kim, Won Jae Lee, Hyunjung Cho, Kun-Hong Lee
Abstract: Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens from Clostridium Perfringens as vaccines to prevent necrotic enteritis (NE).
Type:
Grant
Filed:
August 3, 2018
Date of Patent:
January 10, 2023
Assignee:
University of Florida Research Foundation, Incorporated
Abstract: This document provides methods and materials involved in reducing venous neointimal hyperplasia (VNH) of an arteriovenous fistula (AVF) or graft. For example, methods and materials for using stem cells (e.g., mesenchymal stem cells), extracellular matrix material, or a combination of stem cells and extracellular matrix material to reduce VNH of AVFs or grafts are provided.
Type:
Grant
Filed:
June 17, 2020
Date of Patent:
January 10, 2023
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: Provided is a substrate deforming device for proximity exposure, the device comprising: a mask holder for holding an exposure mask; a first plate which is spaced apart from the exposure mask in a certain direction, and holds a to-be-exposed substrate; a position adjustment part for adjusting the position of the exposure mask; a gap adjustment part for adjusting a gap between the exposure mask and the to-be-exposed substrate; a first sensor for measuring the position of at least one among the exposure mask and the to-be-exposed substrate; a second sensor for measuring the gap between the exposure mask and the to-be-exposed substrate; and a control unit which performs a first control according to the measurement result from the first sensor, and after the first control, performs a second control according to the measurement result from the second sensor. The first control reduces the relative distance between the exposure mask and the to-be-exposed substrate by means of the position adjustment part.
Type:
Grant
Filed:
October 29, 2021
Date of Patent:
January 10, 2023
Assignee:
INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
Abstract: An exemplary integrated nuclear quadrupole resonance-based detection system comprises a front-end device having a hand-held form factor, wherein the front-end device is configured to scan a sample in or near a sample coil using inbuild electronics and acquire a nuclear quadrupole resonance measurement. The system further includes a swappable sample coil that is attached to an opening at a face of the front-end device and is tuned to a resonant frequency of the sample; and a swappable impedance matching network that is attached to the opening at the face of the front-end device and is configured to tune the resonant frequency of the sample coil. The inbuild electronics comprises a wireless transfer module that is configured to communicate the acquired nuclear quadrupole resonance measurement with a back-end device of the integrated nuclear quadrupole resonance-based detection system. Other systems and methods are also provided.
Type:
Grant
Filed:
July 30, 2021
Date of Patent:
January 10, 2023
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
Swarup Bhunia, Naren Vikram Raj Masna, Soumyajit Mandal, David Joseph Ariando